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Yy1 Is Pivotal In The Control Of The Pathogenesis And Drug Resistance Of Cancer

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YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer Book
Author : Benjamin Bonavida
Publisher : Academic Press
Release : 2020-11-02
ISBN : 0128226366
Language : En, Es, Fr & De

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Book Description :

YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic underlying mechanisms by which YY1 regulates its pro-cancerous activities. In addition, it also describes the role of YY1 in the regulation of tumor cell resistance to conventional chemo and immunotherapies and the important role of inhibiting YY1 in cancer. This book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in understanding further the role of YY1 in cancer. Provides a thorough understanding of the underlying mechanisms by which YY1 regulates cancer cell phenotype and unique characteristics Discusses the novel mechanisms of YY1 regulation of tumor cell resistance and means to overcome resistance Encompasses new examples of newly developed non-toxic and selective inhibitors targeting YY1

Sensitization of Cancer Cells for Chemo Immuno Radio therapy

Sensitization of Cancer Cells for Chemo Immuno Radio therapy Book
Author : Benjamin Bonavida
Publisher : Springer Science & Business Media
Release : 2008-07-31
ISBN : 9781597454742
Language : En, Es, Fr & De

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Book Description :

This book reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. It also introduces several current approaches developed by established investigators that are aimed at overcoming resistance. This is the first volume to compile studies on tumor cell sensitization. It will prove useful for students, scientists, clinicians and pharmaceutical companies.