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Wound Healing Biomaterials Volume 1

Wound Healing Biomaterials   Volume 1 Book
Author : Magnus Ågren
Publisher : Woodhead Publishing
Release : 2016-06-03
ISBN : 0081006055
Language : En, Es, Fr & De

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Book Description :

Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care

Wound Healing Biomaterials Volume 2

Wound Healing Biomaterials   Volume 2 Book
Author : Magnus Ågren
Publisher : Woodhead Publishing
Release : 2016-05-30
ISBN : 0081006063
Language : En, Es, Fr & De

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Book Description :

Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. Includes more systematic and comprehensive coverage on the topic of wound care Provides thorough coverage of all specific therapies and biomaterials for wound healing Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more

Wound Healing Biomaterials

Wound Healing Biomaterials Book
Author : Magnus S. Ågren
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Wound Healing Biomaterials book written by Magnus S. Ågren, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advanced Wound Repair Therapies

Advanced Wound Repair Therapies Book
Author : David Farrar
Publisher : Elsevier
Release : 2011-06-21
ISBN : 0857093304
Language : En, Es, Fr & De

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Book Description :

Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds. Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices. With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair

Biomaterials for Treating Skin Loss

Biomaterials for Treating Skin Loss Book
Author : D P Orgill,C Blanco
Publisher : Elsevier
Release : 2009-01-28
ISBN : 1845695542
Language : En, Es, Fr & De

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Book Description :

The primary causes of wounds requiring skin replacement are severe burns and ulcers. Materials must provide an effective temporary barrier, promote healing and minimise scarring. Massive improvements have been made to skin repair biomaterials in the last ten years with widespread adoption of new developments in the medical sector. This book provides a comprehensive review of the range of biomaterials for treating skin loss. Part one discusses the basics of skin replacement with chapters on such topics as markets and regulation, biomechanics and the biological environment of skin. Part two then reviews epidermal and dermal replacement technology with chapters on such topics as alternative delivery of keratinocytes, collagen-based and human origin-based dermal replacement, and lyophilized xenogenic products. The final section explores combined dermis and epidermal replacement technologies and provides a round-up of skin replacement principles. With its distinguished editors and international team of contributors, Biomaterials for treating skin loss is a standard reference for those researching skin replacement technologies, particularly those interested in treating burns and ulcers. Comprehensively reviews the range of biomaterials for treating skin loss and skin replacement principles Examines the basis of skin loss from products and markets through to regulation and the biological environment of skin Highlights developments in epidermal and dermal replacement technology covering topics such as collagen-based and human origin-based dermal replacement

Biomaterials for Skin Repair and Regeneration

Biomaterials for Skin Repair and Regeneration Book
Author : Elena Garcia-Gareta
Publisher : Woodhead Publishing
Release : 2019-06-05
ISBN : 0081025475
Language : En, Es, Fr & De

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Book Description :

Biomaterials for Skin Repair and Regeneration examines a range of materials and technologies used for regenerating or repairing skin. With a strong focus on biomaterials and scaffolds, the book also examines the testing and evaluation pathway for human clinical trials. Beginning by introducing the fundamentals on skin tissue, the book goes on to describe contemporary technology used in skin repair as well as currently available biomaterials suitable for skin tissue repair and regeneration. Skin tissue engineering and the ideal requirements to take into account when developing skin biomaterials are discussed, followed by information on the individual materials used for skin repair and regeneration. As evaluation of biomaterials in animal models is mandatory before proceeding into human clinical trials, the book also examines the different animal models available. With a strong focus on materials, engineering, and application, this book is a valuable resource for materials scientists, skin biologists, and bioengineers with an interest in tissue engineering, regeneration, and repair of skin. Provides an understanding of basic skin biology Comprehensively examines a variety of biomaterial approaches Looks at animal models for the evaluation of biomaterial-based skin constructs

Bioactive Polysaccharide Materials for Modern Wound Healing

Bioactive Polysaccharide Materials for Modern Wound Healing Book
Author : Tina Maver,Uroš Maver,Tanja Pivec,Manja Kurečič,Zdenka Peršin,Karin Stana Kleinschek
Publisher : Springer
Release : 2018-04-23
ISBN : 3319896083
Language : En, Es, Fr & De

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Book Description :

This is the first concise book that includes different aspects of naturally-derived components for wound healing. It presents the first exhaustive review of modern techniques in wound dressing development. With a growing, ageing population and the rapid growth of the wound-care market, the authors explore the current trend of bio-based products (active components and host materials) in this field. After a short introduction into modern solutions in wound-care and modern techniques in wound-dressing development, the authors, leaders in the field, explore natural-based components (drugs, extracts, materials etc.); safety and efficiency assessments (biocompatibility, cytotoxicity and in vitro performance etc.); and model films as a platform for the development of new wound dressings.

Wound Closure Biomaterials and Devices

Wound Closure Biomaterials and Devices Book
Author : Chih-Chang Chu,J. Anthony von Fraunhofer,Howard P. Greisler
Publisher : CRC Press
Release : 2018-05-04
ISBN : 1351404008
Language : En, Es, Fr & De

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Book Description :

"Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï

Natural Polymers in Wound Healing and Repair

Natural Polymers in Wound Healing and Repair Book
Author : Mahesh K. Sah,Naresh Kasoju,Joao F. Mano
Publisher : Elsevier
Release : 2022-06-15
ISBN : 9780323905145
Language : En, Es, Fr & De

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Book Description :

Natural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trends presents comprehensive coverage of the development and the application of natural polymers in wound healing and repair, including fundamental concepts, traditional approaches, cutting-edge methods, and emerging trends. Since the introduction of a supporting matrix is inevitable in critical size wound management, biomaterials have become a central focus of wound healing and repair. A range of biomaterials have been introduced and are still being developed, depending on context and requirements. Due to the precisely controlled structures, processability, and possibilities of presence of cell receptor binding ligands, natural polymers have been explored for application in wound healing and repair. The application of natural polymers has evolved from their use in the simplest wound management material, to drug eluting matrices, to cell-laden constructs, and to 3D bio-printed skin equivalents. This book reflects the remarkable progress that has been made in recent years in this innovative field. This is an essential resource for researchers, scientists, and advanced students across polymer science, biomaterials, bio-based and sustainable materials, biomedicine, biomedical engineering, pharmaceuticals, and materials science and engineering. This book is also valuable to R&D professionals, scientists, technologists, and all those working in a medical setting who are interested in the latest developments in advanced materials for wound management, healing, and repair. Provides up-to-date coverage of natural polymer-based biomaterials in wound healing and repair, covering sources, processing, and properties Describes cellular and molecular events in wound healing and introduces conventional and advanced methodologies for wound management Offers a comprehensive understanding of state-of-the-art and emerging concepts in wound healing, including drug-eluting matrices, cell-laden systems, and personalized bio-fabrication strategies

Tissue Regeneration Using Scaffolding and Biomaterials in Wound Healing Systems

Tissue Regeneration Using Scaffolding and Biomaterials in Wound Healing Systems Book
Author : Terrell Antonio Hilliard
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Tissue Regeneration Using Scaffolding and Biomaterials in Wound Healing Systems book written by Terrell Antonio Hilliard, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Stimulation of Wound Healing and Vascularization with Calcium releasing Biomaterials

Stimulation of Wound Healing and Vascularization with Calcium releasing Biomaterials Book
Author : Claudia Navarro Requena
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Chronic skin wounds are a major socioeconomic burden in developed societies, affecting specially elder and diabetic people. It is estimated that 1 to 2% of the population will suffer a chronic wound in their lifetime and, as global population ages and adopts a sedentary lifestyle, the incidence of these wounds will continue its upward trend. Chronic injuries are characterized for presenting a complicated and diverse pathophysiology that make them resistant to current therapies. For this reason, novel therapeutic strategies based on the release of growth factors and the use of tissue engineered constructs are being investigated and show promising results. However, very few biologically based products reach the market, mainly due to regulatory, economic and stability constraints, amplifying the need for easily translational novel treatments. Recently, inorganic biomaterials known as bioceramics have been acknowledged for their wound healing and vascularization capability, mainly due to their ion release. Based on this concept, the present thesis project was dedicated to investigate the potential application of novel bioceramics on wound healing and soft tissue regeneration. More specifically we focused on the role of the calcium ion and its release from newly designed bioceramics to stimulate wound healing and blood vessel formation in both in vitro and in vivo systems. Although it is known that calcium affects all the phases of wound healing, the concentrations and release profile that can improve the healing process has not been described. For this reason, we evaluated the effect of different concentrations of extracellular calcium in vitro on dermal fibroblast, a crucial cell type in the skin and the healing process, and found stimulation of relevant biological responses at specific concentrations. In addition, we compared whether similar effects could be obtained with the ion release of newly designed bioceramic particles containing equivalent calcium concentrations. Interestingly, while stimulating most of the effects, the ion release inhibited some responses triggered by calcium alone that are not desired in the context of chronic wound healing. Then, we investigated the cellular mechanism mediating some of the responses stimulated by calcium, focusing on the implication of the calcium-sensing receptor (CaSR). Several agonists of the receptor stimulated similar effects than calcium, suggesting the relevance of the CaSR on fibroblasts behavior, and opening a window to the design of novel bioceramics that release CaSR-agonists. In order to test the healing capability of the above mentioned bioceramic particles in vivo, they were incorporated in a mat of poly(lactic acid) (PLA) fibers. This novel dressing was applied on a model of chronic wounds in vivo, and compared with a mat of particle-free PLA and to a frequently used commercially available dressing. We found that the PLA-bioceramic mat accelerated wound closure and increased vasculature at the injured site at initial time-points. Thus, improved healing was achieved with the newly designed dressing. Finally, a different composite material was synthesized combining bioceramic particles and human mesenchymal stromal cells (hMSC) in a degradable hydrogel, and its vasculogenic potential was evaluated in soft tissue. This material supported hMSC survival and stimulated the release of the angiogenic factor IGF-1 from these cells in vitro. In addition, when implanted in soft tissue of immunocompromised mice, the composite construct improved hMSC survival and generated a more mature vasculature at the site of implantation. In conclusion, this thesis shows that calcium-releasing bioceramics can successfully contribute to the treatment of chronic wounds and soft tissue regeneration.

Soy Protein Based Biomaterials for Soft Tissue Engineering and Wound Healing

Soy Protein Based Biomaterials for Soft Tissue Engineering and Wound Healing Book
Author : Samira Tansaz
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Soy Protein Based Biomaterials for Soft Tissue Engineering and Wound Healing book written by Samira Tansaz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomimetic biomaterials

Biomimetic biomaterials Book
Author : E. Boughton,S.V. Mclennan
Publisher : Elsevier Inc. Chapters
Release : 2013-09-30
ISBN : 0128088133
Language : En, Es, Fr & De

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Book Description :

Scaffolds are increasingly being used to repair skin lesions, in particular in acute conditions such as burns. Their use in the repair of chronic wounds is less well established, but they offer a potential solution to this debilitating condition. The biomimetic approach of mimicking the structure and function of the dermis via design of scaffolds for soft tissue repair marks a shift from the traditional approach of simple replacement of tissue and has potential to improve healing in chronic wounds. This chapter will focus on a review of the scaffolds currently used for skin repair and examine their utility for repair of chronic wounds.

Bioactive Glass Based Injectable Biomaterials for Wound Healing Applications

Bioactive Glass Based Injectable Biomaterials for Wound Healing Applications Book
Author : Pegah Hassanzadeh
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Bioactive Glass Based Injectable Biomaterials for Wound Healing Applications book written by Pegah Hassanzadeh, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomaterials Medical Devices and Tissue Engineering An Integrated Approach

Biomaterials  Medical Devices and Tissue Engineering  An Integrated Approach Book
Author : F.H. Silver
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 9401107351
Language : En, Es, Fr & De

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Book Description :

are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.

Bioengineering In Wound Healing A Systems Approach

Bioengineering In Wound Healing  A Systems Approach Book
Author : Yarmush Martin L,Golberg Alexander
Publisher : World Scientific
Release : 2017-03-24
ISBN : 9813144599
Language : En, Es, Fr & De

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Book Description :

What is a wound, how does it heal, and how can we prevent scarring? The concept of wound healing has puzzled humans even before the advent of modern medicine. In recent years, bioengineering has tackled the problems of cancer, tissue engineering and molecular manufacturing. The broad spectrum of technologies developed in these fields could potentially transform the wound care practice. However, entering the world of wound healing research is challenging — a broad spectrum of knowledge is required to understand wounds and improve healing. This book provides an essential introduction of the field of wound healing to bioengineers and scientists outside the field of medicine. Written by leading researchers from various fields, this book is a comprehensive primer that gives readers a holistic understanding of the field of wound biology, diagnostics and treatment technologies. Contents:Scarless Tissue Regeneration (Alexander Golberg)Anatomy of the Human Skin and Wound Healing (Amit Sharma, Labib R Zakka and Martin C Mihm Jr)Deprived and Enriched Environments: How Sensory Stimulation Affects Wound Healing (Jonathan G Fricchione and John B Levine)Models of Ischemic and Vascular Wounds (Michael T Watkins and Hassan Albadawi)Developmental Biology of Skin Wound Healing: On Pathways and Genes Controlling Regeneration Versus Scarring (Sarah Susan Kelangi and Marianna Bei)Nutrition, Metabolism, and Wound Healing Process (Yong-Ming Yu and Alan J Fischman)Polarization Sensitive Optical Coherence Tomography for Imaging of Wound Repair (Martin Villiger and Brett E Bouma)Functional Imaging of Wound Metabolism (Jake Jones, Vasily Belov and Kyle P Quinn)Functional Skin Substitutes — The Intersection of Tissue Engineering and Biomaterials (Kevin Dooley, Julie Devalliere and Basak Uygun)Biomaterial-Based Systems for Pharmacologic Treatment of Wound Repair (Mara A Pop, Julia B Sun and Benjamin D Almquist)Laser Tissue Welding in Wound Healing and Surgical Repair (Russell Urie, Tanner Flake and Kaushal Rege)Bioprinting for Wound Healing Applications (Aleksander Skardal, Sean Murphy, Anthony Atala and Shay Soker)Electroporation Applications in Wound Healing (Laure Gibot, Tadej Kotnik and Alexander Golberg) Readership: Bioengineers, scientists, researchers and graduate students outside the field of medicine.

An Introduction to Tissue Biomaterial Interactions

An Introduction to Tissue Biomaterial Interactions Book
Author : Kay C. Dee,David A. Puleo,Rena Bizios
Publisher : John Wiley & Sons
Release : 2003-04-14
ISBN : 0471461121
Language : En, Es, Fr & De

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Book Description :

An Introduction to Tissue-Biomaterial Interactions acquaintsan undergraduate audience with the fundamental biological processesthat influence these sophisticated, cutting-edge procedures.Chapters one through three provide more detail about themolecular-level events that happen at the tissue-implant interface,while chapters four through ten explore selected material,biological, and physiological consequences of these events. Theimportance of the body’s wound-healing response is emphasizedthroughout. Specific topics covered include:Structure andproperties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples oftissue-biomaterial interactions The text also provides extensive coverage of the three pertinentinterfaces between the body and the biomaterial, between the bodyand the living cells, and between the cells and the biomaterialthat are critical in the development of tissue-engineered productsthat incorporate living cells within a biomaterial matrix. Idealfor a one-semester, biomedical engineering course, An Introductionto Tissue-Biomaterial Interactions provides a solid framework forunderstanding today’s and tomorrow’s implantablebiomedical devices.

Emerging Markets in Tissue Engineering

Emerging Markets in Tissue Engineering Book
Author : Pamela Bassett
Publisher : D&md Reports
Release : 1999-01-01
ISBN : 9781579361419
Language : En, Es, Fr & De

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Book Description :

Download Emerging Markets in Tissue Engineering book written by Pamela Bassett, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biopolymers as Wound Healing Materials Challenges and New Strategies

Biopolymers as Wound Healing Materials  Challenges and New Strategies Book
Author : Ali Demir Sezer,Erdal Cevher
Publisher : Unknown
Release : 2011
ISBN : 9789533076614
Language : En, Es, Fr & De

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Book Description :

Download Biopolymers as Wound Healing Materials Challenges and New Strategies book written by Ali Demir Sezer,Erdal Cevher, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.