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Virus as Populations

Virus as Populations Book
Author : Esteban Domingo
Publisher : Academic Press
Release : 2019-11-06
ISBN : 0128163321
Language : En, Es, Fr & De

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Book Description :

Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Quasispecies Concept and Implications for Virology

Quasispecies  Concept and Implications for Virology Book
Author : Esteban Domingo
Publisher : Springer Science & Business Media
Release : 2006-02-19
ISBN : 3540263977
Language : En, Es, Fr & De

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Book Description :

Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.

Emerging Viruses in Human Populations

Emerging Viruses in Human Populations Book
Author : Edward Tabor
Publisher : Elsevier
Release : 2006-12-19
ISBN : 9780080467900
Language : En, Es, Fr & De

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Book Description :

Infectious diseases are an ever present threat to humans. In recent years, the threat of these emerging viruses has been greater than ever before in human history, due in large part to global travel by larger numbers of people, and to a lesser extent to disruptions in the interface between developed and undeveloped areas. The emergence of new deadly viruses in human populations during recent decades has confirmed this risk. They remain the third leading cause of deaths in the US and the second world-wide. Emerging Viruses in Human Populations provides a comprehensive review of viruses that are emerging or that threaten to emerge among human populations in the twenty-first century. It discusses the apprehension over emerging viruses that has intensified due to concerns about bioterrorism. * Presents the history of emerging viruses * Includes chapters on SARS, Pandemic Threat of Avian Influenza Viruses, West Nile Virus, Monkeypox Virus, Hantavirus, Nipah Virus and Hendra Virus, Japanese Encephalitis Virus, Dengue and Crimean-Congo Hemorrhagic Fever Viruses * Discusses surveillance for newly emerging diseases

Plant Virus Evolution

Plant Virus Evolution Book
Author : Marilyn J. Roossinck
Publisher : Springer Science & Business Media
Release : 2008-02-23
ISBN : 9783540757634
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive look at the field of plant virus evolution. It is the first book ever published on the topic. Individual chapters, written by experts in the field, cover plant virus ecology, emerging viruses, plant viruses that integrate into the host genome, population biology, evolutionary mechanisms and appropriate methods for analysis. It covers RNA viruses, DNA viruses, pararetroviruses and viroids, and presents a number of thought-provoking ideas.

Journal of the National Cancer Institute

Journal of the National Cancer Institute Book
Author : Anonim
Publisher : Unknown
Release : 1974-03
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of the National Cancer Institute book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Basis of Virus Evolution

Molecular Basis of Virus Evolution Book
Author : Adrian J. Gibbs,Charles H. Calisher,Fernando GarcĂ­a-Arenal
Publisher : Cambridge University Press
Release : 2005-11-17
ISBN : 9780521022897
Language : En, Es, Fr & De

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Book Description :

This 1995 book covers virus evolution, genetics and interaction with host for virologists and evolutionists.

From Virus Populations to Epidemics

From Virus Populations to Epidemics Book
Author : Duncam Stewart Callaway
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The study of the population dynamics of disease ranges from the scale of individual cells interacting with virus particles to the structure of the host interaction network. This thesis represents a broad survey of the mathematics of disease across these scales. I have used differential equations to examine the role of competition among viral strains on the progression of HIV infected persons to AIDS, and the factors that lead to the persistence of viral replication in HIV patients undergoing potent drug therapies. At the epidemic level, I have used difference equations to understand the effect of pathogen mutation and host immunity on disease persistence. I have used generating function methods and concepts from graph theory to probe the kinds of host interactions, in particular the distribution of contact rates, which lead to successful vaccination programs. Lastly, I have explored a model of network growth to examine the assumptions made in previous work.

Virology Acute viral infections

Virology  Acute viral infections Book
Author : National Institutes of Health (U.S.)
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Virology Acute viral infections book written by National Institutes of Health (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Federation Proceedings

Federation Proceedings Book
Author : Federation of American Societies for Experimental Biology
Publisher : Unknown
Release : 1962
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Federation Proceedings book written by Federation of American Societies for Experimental Biology, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Annual Progress Report U S Army Medical Research Institute of Infectious Diseases

Annual Progress Report   U  S  Army Medical Research Institute of Infectious Diseases Book
Author : United States Army Medical Research Institute of Infectious Diseases
Publisher : Unknown
Release : 1975
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annual Progress Report U S Army Medical Research Institute of Infectious Diseases book written by United States Army Medical Research Institute of Infectious Diseases, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Effect of Within host Virus Population Growth and Interspecific Competition on Aphid Transmission and Population Structure of Barley Yellow Dwarf Virus

The Effect of Within host Virus Population Growth and Interspecific Competition on Aphid Transmission and Population Structure of Barley Yellow Dwarf Virus Book
Author : Gerod Sharper Hall
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Barley yellow dwarf virus (BYDV) (Luteoviridae) species PAV and PAS are ecologically similar in that they share aphid vectors and host species, but in agricultural fields in New York State we found that the prevalence of PAV was three times greater than that of PAS. To determine if differences in within-host population growth rate affect vector transmission efficiency, disease spread and the distribution of virus types in the host community, this study evaluated the biological characteristics of PAV and PAS species isolates in common agricultural hosts and the outcome of competitive interactions between species in mixed infections. In singly infected plants, PAS population size was 20% greater than that of PAV at 8 days post inoculation (DPI), but by 33 DPI the population size of PAV was 10% greater than that of PAS. In doubly infected plants, by 33 DPI the population size of PAV was 40% greater than that of PAS.

Diversity of Plant Virus Populations A Valuable Tool for Epidemiological Studies

Diversity of Plant Virus Populations  A Valuable Tool for Epidemiological Studies Book
Author : Fernando Escriu
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Plant viruses, as any other living organisms, differ genetically from each other as a result of processes (such as mutation, recombination and other forms of genetic exchange) that generate genetic variation in each generation during their reproduction and processes (such as selection, migration and genetic drift) that modulate this variation, determine the distribution of the genetic variants within a population (id est, the genetic structure of the population) and how it changes with time, in a dynamical phenomenon called evolution. For plant viruses, evolutionary forces that generate and modulate the genetic diversity of their populations are often associated to different phases in their biology and ecology, such as virus-host interactions and host to host transmission. Forces that shape the evolution of plant viruses are at the same time key factors affecting their pathogenic properties, including their ability to cause diseases (an aspect that is studied in the field of epidemiology). The present chapter aims to illustrate how measurement and analysis of genetic diversity and structure of plant virus populations are essential to the current knowledge on the evolutionary biology of plant viruses and how evolutionary factors have a relevant role in the dynamics of virus populations and therefore, in the epidemiology of plant virus diseases.

Journal

Journal Book
Author : National Cancer Institute (U.S.)
Publisher : Unknown
Release : 1969-07
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal book written by National Cancer Institute (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Virus Dynamics Mathematical Principles of Immunology and Virology

Virus Dynamics   Mathematical Principles of Immunology and Virology Book
Author : Martin Nowak,Robert M. May
Publisher : Oxford University Press, UK
Release : 2000-11-23
ISBN : 0191588512
Language : En, Es, Fr & De

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Book Description :

This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature

Biology of Populations

Biology of Populations Book
Author : Brenda K. Sladen,F. Sladen,Frederik Barry Bang
Publisher : Elsevier Publishing Company
Release : 1969
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book provides a collection of essays on population dynamics and other aspects of ecology, population genetics, ethology, and the nature of interactions of populations in disease. These essays illustrate how animal and plant biology supports public health.

Mucosal Transmission of Simian Immunodeficiency Virus in Rhesus Macaques

Mucosal Transmission of Simian Immunodeficiency Virus in Rhesus Macaques Book
Author : Jennifer Lea Greenier
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Mucosal Transmission of Simian Immunodeficiency Virus in Rhesus Macaques book written by Jennifer Lea Greenier, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Collected Reprints on Research by Grantees

Collected Reprints on Research by Grantees Book
Author : National Foundation
Publisher : Unknown
Release : 1959
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Collected Reprints on Research by Grantees book written by National Foundation, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fifth International Mycological Congress

Fifth International Mycological Congress Book
Author : Anonim
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Fifth International Mycological Congress book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Insect Viruses

Insect Viruses Book
Author : Karl Maramorosch
Publisher : Unknown
Release : 1968
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Insect Viruses book written by Karl Maramorosch, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bluetongue Virus

Bluetongue Virus Book
Author : Kyle Russell Bonneau
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Bluetongue Virus book written by Kyle Russell Bonneau, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.