Skip to main content

Virus As Populations

In Order to Read Online or Download Virus As Populations Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Virus as Populations

Virus as Populations Book
Author : Esteban Domingo
Publisher : Academic Press
Release : 2019-11-06
ISBN : 0128163321
Language : En, Es, Fr & De

GET BOOK

Book Description :

Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Virus As Populations

Virus As Populations Book
Author : Esteban Domingo
Publisher : Academic Press
Release : 2015-10-01
ISBN : 9780128008379
Language : En, Es, Fr & De

GET BOOK

Book Description :

Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere. Features current views on the key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

The Nature of RNA Virus Quasispecies Populations

The Nature of RNA Virus Quasispecies Populations Book
Author : Elizabeth Anne Duarte
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download The Nature of RNA Virus Quasispecies Populations book written by Elizabeth Anne Duarte, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Plant Virus Evolution

Plant Virus Evolution Book
Author : Marilyn J. Roossinck
Publisher : Springer Science & Business Media
Release : 2008-02-23
ISBN : 9783540757634
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book provides a comprehensive look at the field of plant virus evolution. It is the first book ever published on the topic. Individual chapters, written by experts in the field, cover plant virus ecology, emerging viruses, plant viruses that integrate into the host genome, population biology, evolutionary mechanisms and appropriate methods for analysis. It covers RNA viruses, DNA viruses, pararetroviruses and viroids, and presents a number of thought-provoking ideas.

The Evolution and Emergence of RNA Viruses

The Evolution and Emergence of RNA Viruses Book
Author : Edward C. Holmes
Publisher : Oxford University Press
Release : 2009-06-25
ISBN : 0199211124
Language : En, Es, Fr & De

GET BOOK

Book Description :

While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.

Emerging Viruses in Human Populations

Emerging Viruses in Human Populations Book
Author : Edward Tabor
Publisher : Elsevier
Release : 2006-12-19
ISBN : 9780080467900
Language : En, Es, Fr & De

GET BOOK

Book Description :

Infectious diseases are an ever present threat to humans. In recent years, the threat of these emerging viruses has been greater than ever before in human history, due in large part to global travel by larger numbers of people, and to a lesser extent to disruptions in the interface between developed and undeveloped areas. The emergence of new deadly viruses in human populations during recent decades has confirmed this risk. They remain the third leading cause of deaths in the US and the second world-wide. Emerging Viruses in Human Populations provides a comprehensive review of viruses that are emerging or that threaten to emerge among human populations in the twenty-first century. It discusses the apprehension over emerging viruses that has intensified due to concerns about bioterrorism. * Presents the history of emerging viruses * Includes chapters on SARS, Pandemic Threat of Avian Influenza Viruses, West Nile Virus, Monkeypox Virus, Hantavirus, Nipah Virus and Hendra Virus, Japanese Encephalitis Virus, Dengue and Crimean-Congo Hemorrhagic Fever Viruses * Discusses surveillance for newly emerging diseases

Genetic Diversity of RNA Viruses

Genetic Diversity of RNA Viruses Book
Author : John J. Holland
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642770118
Language : En, Es, Fr & De

GET BOOK

Book Description :

Many RNA viruses have been known for decades to be genetically and biologically quite variable. Some well-known examples are influenza viruses, foot and mouth disease viruses, and Newcastle disease virus. During the past decade, it has become clear that most, it not all. , RNA viruses (riboviruses and retroviruses) are much more mutable than was recognized previously, and that this great mutability generates extremely complex populations consisting of indeterminate mixtures of related variants (Le. , "mutant swarms" or "quasispecies" populations). This is also true of DNA viruses (such as hepatitis DNA genomes via RNA transcripts B virus) which replicate their that are reverse-transcribed back to DNA. This hypermutability of RNA replicons provides great biological adaptability for RNA virus genomes. It also allows (but does not necessitate) RNA viruses, so that they can extremely rapid evolution of evolve over a million times more quickly than their eukaryotic DNA-based hosts. The genetics of RNA replicons is so unusual (and often counterintuitive) that it has many important biological conse quences which are neither readily apparent nor widely under stood. Failure to understand the distinctive aspects of RNA genetics frequently generates confusion and controversy and can adversely impact vaccine and antiviral drug programs and other applications of medical virology. The 14 chapters in this volume describe advances in a number of significant areas of RNA virus genetics and evolution.

Genetic Variation and Evolution of Equine Infectious Anemia Virus Rev Quasispecies During Long Term Persistent Infection

Genetic Variation and Evolution of Equine Infectious Anemia Virus Rev Quasispecies During Long Term Persistent Infection Book
Author : Prasith Baccam
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

These two quasispecies populations differed in their pattern of evolution, with one population accumulating changes in a linear, time-dependent manner, while the other population evolved radially from a common variant. Changes in the population size of the two Rev quasispecies coincided with changes in the clinical stages of disease. Rev variants from each population were biologically tested, and significant differences in Rev activity were detected between the two populations. Together, these results suggested that the distinct Rev populations differed in selective advantage. A statistical correlation was found between Rev quasispecies activity and temperature of the pony over the course of infection. Furthermore, the Rev quasispecies activity differed significantly between different stages of clinical disease. This study suggests that distinct quasispecies populations, which differed in pattern of evolution and niche advantage, co-existed during long term persistent infection by EIAV. A multi-population quasispecies model challenges our current thinking of viral populations and may have significant biological implications.

Viruses as Complex Adaptive Systems

Viruses as Complex Adaptive Systems Book
Author : Ricard Solé,Santiago F. Elena
Publisher : Princeton University Press
Release : 2018-12-11
ISBN : 0691158843
Language : En, Es, Fr & De

GET BOOK

Book Description :

How complex systems theory sheds new light on the adaptive dynamics of viral populations Viruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts. New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances. Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages.

Virus as Populations

Virus as Populations Book
Author : Esteban Domingo
Publisher : Academic Press
Release : 2015-09-25
ISBN : 0128009942
Language : En, Es, Fr & De

GET BOOK

Book Description :

Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere. Features current views on the key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Fitness Evolution and Generation of Resistant Variants During Large Population Transmission of Vesicular Stomatitis Virus in Interferon treated Cells

Fitness Evolution and Generation of Resistant Variants During Large Population Transmission of Vesicular Stomatitis Virus in Interferon treated Cells Book
Author : Martin J. Cilnis
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Fitness Evolution and Generation of Resistant Variants During Large Population Transmission of Vesicular Stomatitis Virus in Interferon treated Cells book written by Martin J. Cilnis, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Quasispecies Concept and Implications for Virology

Quasispecies  Concept and Implications for Virology Book
Author : Esteban Domingo
Publisher : Springer Science & Business Media
Release : 2006-02-19
ISBN : 3540263977
Language : En, Es, Fr & De

GET BOOK

Book Description :

Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.

Quantitative Viral Ecology

Quantitative Viral Ecology Book
Author : Joshua S. Weitz
Publisher : Princeton University Press
Release : 2016-01-05
ISBN : 0691161542
Language : En, Es, Fr & De

GET BOOK

Book Description :

When we think about viruses we tend to consider ones that afflict humans—such as those that cause influenza, HIV, and Ebola. Yet, vastly more viruses infect single-celled microbes. Diverse and abundant, microbes and the viruses that infect them are found in oceans, lakes, plants, soil, and animal-associated microbiomes. Taking a vital look at the "microscopic" mode of disease dynamics, Quantitative Viral Ecology establishes a theoretical foundation from which to model and predict the ecological and evolutionary dynamics that result from the interaction between viruses and their microbial hosts. Joshua Weitz addresses three major questions: What are viruses of microbes and what do they do to their hosts? How do interactions of a single virus-host pair affect the number and traits of hosts and virus populations? How do virus-host dynamics emerge in natural environments when interactions take place between many viruses and many hosts? Emphasizing how theory and models can provide answers, Weitz offers a cohesive framework for tackling new challenges in the study of viruses and microbes and how they are connected to ecological processes—from the laboratory to the Earth system. Quantitative Viral Ecology is an innovative exploration of the influence of viruses in our complex natural world.

Virus Dynamics Archaeal Populations and Water Chemistry of Three Acidic Hot Springs in Yellowstone National Park

Virus Dynamics  Archaeal Populations  and Water Chemistry of Three Acidic Hot Springs in Yellowstone National Park Book
Author : Jamie Christine Snyder
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

These three sites were monitored continuously for changes in virus populations, archaeal host populations, and water chemistry. Each monitor site was chemically unique, but the water chemistry did not significantly change over time. The archaeal population in each of the three hot springs was unique and was found to slowly change over time. We have discovered that although there can be a substantial change in viral population structures in between the collection of samples, it does not seem to be correlated with a changing environmental parameter. There also appears to be a strong culturing bias present in the SSVs when we compare the virus population monitored directly from the environment to the viruses isolated from an enrichment culture established from a particular hot spring. A long term goal is to contribute to the understanding of the relationships between time and resident viral populations within hot spring environments. We hope this work will contribute a further understanding of life in extreme environments.

Virus Dynamics Mathematical Principles of Immunology and Virology

Virus Dynamics   Mathematical Principles of Immunology and Virology Book
Author : Martin Nowak,Robert M. May
Publisher : Oxford University Press, UK
Release : 2000-11-23
ISBN : 0191588512
Language : En, Es, Fr & De

GET BOOK

Book Description :

This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature

The Persistence of Nuclear Polyhedrosis Virus and Entomopoxvirus in Populations of Spruce Budworm

The Persistence of Nuclear Polyhedrosis Virus and Entomopoxvirus in Populations of Spruce Budworm Book
Author : J. C. Cunningham,Canadian Forestry Service. Insect Pathology Research Institute, Sault Ste. Marie
Publisher : sault ste. marie, ont. : canadian forestry service
Release : 1975
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download The Persistence of Nuclear Polyhedrosis Virus and Entomopoxvirus in Populations of Spruce Budworm book written by J. C. Cunningham,Canadian Forestry Service. Insect Pathology Research Institute, Sault Ste. Marie, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Changing Perspectives

Changing Perspectives Book
Author : Femke A. E. Lambers
Publisher : Unknown
Release : 2020
ISBN : 9789463758147
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Changing Perspectives book written by Femke A. E. Lambers, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Quasispecies Concept and Implications for Virology

Quasispecies  Concept and Implications for Virology Book
Author : Esteban Domingo
Publisher : Springer
Release : 2005-12-21
ISBN : 9783540263951
Language : En, Es, Fr & De

GET BOOK

Book Description :

Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.

Polymerase Error Frequencies Population Equilibria and Evolution of RNA Viruses

Polymerase Error Frequencies  Population Equilibria  and Evolution of RNA Viruses Book
Author : David Allen Steinhauer
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Polymerase Error Frequencies Population Equilibria and Evolution of RNA Viruses book written by David Allen Steinhauer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Aphid Transmission of Blueberry Shoestring Virus and Seasonal Populations of Its Vector Illinois Pepperi MacGillivray

Aphid Transmission of Blueberry Shoestring Virus and Seasonal Populations of Its Vector Illinois Pepperi  MacGillivray  Book
Author : Kathryn Margaret Morimoto
Publisher : Unknown
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Aphid Transmission of Blueberry Shoestring Virus and Seasonal Populations of Its Vector Illinois Pepperi MacGillivray book written by Kathryn Margaret Morimoto, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.