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Vaccines For Biodefense And Emerging And Neglected Diseases

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Vaccines for Biodefense and Emerging and Neglected Diseases

Vaccines for Biodefense and Emerging and Neglected Diseases Book
Author : Alan D.T. Barrett,Lawrence R. Stanberry
Publisher : Academic Press
Release : 2009-03-05
ISBN : 9780080919027
Language : En, Es, Fr & De

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Book Description :

The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. * Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats * Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace * Each chapter will include a map of the world showing where that particular disease is naturally found

Vaccinology

Vaccinology Book
Author : W. John W. Morrow,Nadeem A. Sheikh,Clint S. Schmidt,D. Huw Davies
Publisher : John Wiley & Sons
Release : 2012-06-12
ISBN : 1118345347
Language : En, Es, Fr & De

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Book Description :

Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.

Human Subjects Research after the Holocaust

Human Subjects Research after the Holocaust Book
Author : Sheldon Rubenfeld,Susan Benedict
Publisher : Springer
Release : 2014-06-30
ISBN : 3319057022
Language : En, Es, Fr & De

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Book Description :

“An engaging, compelling and disturbing confrontation with evil ...a book that will be transformative in its call for individual and collective moral responsibility." – Michael A. Grodin, M.D., Professor and Director, Project on Medicine and the Holocaust, Elie Wiesel Center for Judaic Studies, Boston University Human Subjects Research after the Holocaust challenges you to confront the misguided medical ethics of the Third Reich personally, and to apply the lessons learned to contemporary human subjects research. While it is comforting to believe that Nazi physicians, nurses, and bioscientists were either incompetent, mad, or few in number, they were, in fact, the best in the world at the time, and the vast majority participated in the government program of “applied biology.” They were not coerced to behave as they did—they enthusiastically exploited widely accepted eugenic theories to design horrendous medical experiments, gas chambers and euthanasia programs, which ultimately led to mass murder in the concentration camps. Americans provided financial support for their research, modeled their medical education and research after the Germans, and continued to perform unethical human subjects research even after the Nuremberg Doctors’ Trial. The German Medical Association apologized in 2012 for the behavior of its physicians during the Third Reich. By examining the medical crimes of human subjects researchers during the Third Reich, you will naturally examine your own behavior and that of your colleagues, and perhaps ask yourself "If the best physicians and bioscientists of the early 20th century could do evil while believing they were doing good, can I be certain that I will never do the same?"

Neglected Tropical Diseases Sub Saharan Africa

Neglected Tropical Diseases   Sub Saharan Africa Book
Author : John Gyapong,Boakye Boatin
Publisher : Springer
Release : 2016-01-13
ISBN : 3319254715
Language : En, Es, Fr & De

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Book Description :

This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.

Vaccination Controversies A Reference Handbook

Vaccination Controversies  A Reference Handbook Book
Author : David E. Newton
Publisher : ABC-CLIO
Release : 2013-03-21
ISBN : 1610693124
Language : En, Es, Fr & De

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Book Description :

Why is there such an active and ongoing resistance to mandatory vaccination? This book examines why vaccination as a public health measure continues to be highly controversial.

Vaccinophobia and Vaccine Controversies of the 21st Century

Vaccinophobia and Vaccine Controversies of the 21st Century Book
Author : Archana Chatterjee
Publisher : Springer Science & Business Media
Release : 2013-06-25
ISBN : 1461474388
Language : En, Es, Fr & De

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Book Description :

Vaccinophobia and Vaccine Controversies of the 21st Century Archana Chatterjee, editor Once hailed as a medical miracle, vaccination has come under attack from multiple fronts, including occasionally from within medicine. And while the rates of adverse reactions remain low, suggestions that vaccines can cause serious illness (and even death) are inspiring parents to refuse routine immunizations for their children--ironically, exposing them and others to potentially serious illness. Vaccinophobia and Vaccine Controversies of the 21st Century explains clearly how this state of affairs came into being, why it persists, and how healthcare professionals can best respond. Current findings review answers to bedrock questions about known adverse events, what vaccine additives are used for, and real and perceived risks involved in immunization. Perspectives representing pediatricians, family practitioners, nurses, parents, pharmacy professionals, the CDC, and the public health community help the reader sort out legitimate from irrational concerns. In-depth analyses discuss the possibility of links with asthma, cancer, Guillain-Barre syndrome, SIDS, and, of course, autism. Included in the coverage: Communicating vaccine risks and benefits The vaccine misinformation landscape in family medicine Perceived risks from live viral vaccines The media's role in vaccine misinformation Autoimmunity, allergies, asthma, and a relationship to vaccines Vaccines and autism: the controversy that won't go away The conundrums described here are pertinent to practitioners in pediatrics, family medicine, primary care, and nursing to help families with informed decision making. In addition, Vaccinophobia and Vaccine Controversies of the 21st Century should be read by trainees and researchers in child development and maternal and child health as the book's issues will have an impact on future generations of children and their families.

Novel Technologies for Vaccine Development

Novel Technologies for Vaccine Development Book
Author : Igor S Lukashevich,Haval Shirwan
Publisher : Springer
Release : 2014-11-13
ISBN : 3709118182
Language : En, Es, Fr & De

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Book Description :

This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.

Mandell Douglas and Bennett s Principles and Practice of Infectious Diseases E Book

Mandell  Douglas  and Bennett s Principles and Practice of Infectious Diseases E Book Book
Author : John E. Bennett,Raphael Dolin,Martin J. Blaser
Publisher : Elsevier Health Sciences
Release : 2019-08-08
ISBN : 0323550274
Language : En, Es, Fr & De

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Book Description :

For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips. Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource. Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis. Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases. Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases. Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci. PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America. Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition.

Manual of Security Sensitive Microbes and Toxins

Manual of Security Sensitive Microbes and Toxins Book
Author : Dongyou Liu
Publisher : CRC Press
Release : 2014-04-08
ISBN : 1466553960
Language : En, Es, Fr & De

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Book Description :

Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern. The ultimate goal is to increase our awareness of these agents and enhance our preparedness against any future bio-emergencies. The book begins with an introduction containing a brief overview of the historical aspects of security sensitive microbes and toxins. This is followed by a concise summary of the current status in relation to the regulation of security sensitive microbes and toxins and a discussion of future development trends. The book is divided into seven parts: Microbes and Toxins Affecting Humans and Animals: Viruses Microbes and Toxins Affecting Human and Animals: Bacteria Microbes and Toxins Affecting Human and Animals: Fungus and Parasite Microbes and Toxins Affecting Human and Animals: Toxins Microbes Affecting Animals: Viruses Microbes Affecting Animals: Bacteria Microbes Affecting Plants Written by experts in the relevant areas of research, the chapters are authoritative reviews, each one covering a single microbe or toxin with respect to its classification, biology, epidemiology, pathogenesis, identification, diagnosis, treatment, and prevention. The chapters also discuss the limitations of our current knowledge and challenges relating to improved detection and control of the microbe or toxin.

Tropical Infectious Diseases Principles Pathogens and Practice E Book

Tropical Infectious Diseases  Principles  Pathogens and Practice E Book Book
Author : Richard L. Guerrant,David H. Walker,Peter F. Weller
Publisher : Elsevier Health Sciences
Release : 2011-04-05
ISBN : 1437737773
Language : En, Es, Fr & De

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Book Description :

Tropical Infectious Diseases: Principles, Pathogens and Practice, by Drs. Richard L. Guerrant, David H. Walker, and Peter F. Weller, delivers the expert, encyclopedic guidance you need to overcome the toughest clinical challenges in diagnosing and treating diseases caused by infectious agents from tropical regions. Sweeping updates to this 3rd edition include vaccines, SARS, hepatitis A-E, Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis and Omsk hemorrhagic fever, human papilloma virus, and mucormycosis. New full-color images throughout allow you to more accurately view the clinical manifestations of each disease and better visualize the life cycles of infectious agents. Definitive, state-of-the-art coverage of pathophysiology as well as clinical management makes this the reference you’ll want to consult whenever you are confronted with tropical infections, whether familiar or unfamiliar! Obtain complete and trustworthy advice from hundreds of the leading experts on tropical diseases worldwide, including cutting-edge summaries of pathophysiology and epidemiology as well as clinical management. Get the latest answers on vaccines, SARS, hepatitis A-E, Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis and Omsk hemorrhagic fever, human papilloma virus, mucormycosis, and much more. Implement best practices from all over the world with guidance from almost twice as many international authors - over 100 representing more than 35 countries. Accurately view the clinical manifestations of each disease and visualize the life cycles of infectious agents with new full-color images throughout.

Chagas Disease

Chagas Disease Book
Author : Anonim
Publisher : Academic Press
Release : 2011-08-03
ISBN : 012385864X
Language : En, Es, Fr & De

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Book Description :

This thematic volume provides authoritative, up-to-date reviews addressing recent advances as well as an overview for the research and clinical communities on the endemic infection of Chagas disease. Lead researchers discuss epidemiology and control measures as well as various diagnosis techniques, treatments, and therapies currently being used. The text includes a history of Chagas disease and an outlook for the next century. Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts

Insight and Control of Infectious Disease in Global Scenario

Insight and Control of Infectious Disease in Global Scenario Book
Author : Roy Priti
Publisher : BoD – Books on Demand
Release : 2012-03-21
ISBN : 9535103199
Language : En, Es, Fr & De

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Book Description :

This book is projected as a preliminary manuscript in Infectious Disease. It is undertaken to cover the foremost basic features of the articles. Infectious Disease and analogous phenomenon have been one of the main imperative postwar accomplishments in the world. The book expects to provide its reader, who does not make believe to be a proficient mathematician, an extensive preamble to the field of infectious disease. It may immeasurably assist the Scientists and Research Scholars for continuing their investigate workings on this discipline. Numerous productive and precise illustrated descriptions with a number of analyses have been included. The book offers a smooth and continuing evolution from the principally disease oriented lessons to a logical advance, providing the researchers with a compact groundwork for upcoming studies in this subject.

Vaccinology

Vaccinology Book
Author : Gregg N. Milligan,Alan D. T. Barrett
Publisher : John Wiley & Sons
Release : 2015-02-16
ISBN : 0470656166
Language : En, Es, Fr & De

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Book Description :

Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Advances in Flavivirus Research

Advances in Flavivirus Research Book
Author : Michael R. Holbrook
Publisher : MDPI
Release : 2018-07-10
ISBN : 3038424862
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "Advances in Flavivirus Research" that was published in Viruses

Who Expert Committee on Biological Standardization

Who Expert Committee on Biological Standardization Book
Author : WHO Expert Committee on Biological Standardization. Meeting,World Health Organization,World Health Organization. Expert Committee on Biological Standardization
Publisher : World Health Organization
Release : 2013
ISBN : 9241209798
Language : En, Es, Fr & De

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Book Description :

"The WHO Expert Committee on Biological Standardization (ECBS) met in Geneva from 17 to 21 October 2011"--Introduction.

Bioinspired and Biomimetic Materials for Drug Delivery

Bioinspired and Biomimetic Materials for Drug Delivery Book
Author : Md Nurunnabi
Publisher : Woodhead Publishing
Release : 2021-07-30
ISBN : 0128219491
Language : En, Es, Fr & De

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Book Description :

Bioinspired and Biomimetic Materials for Drug Delivery delves into the potential of bioinspired materials in drug delivery, detailing each material type and its latest developments. In the last decade, biomimetic and bioinspired materials and technology has garnered increased attention in drug delivery research. Various material types including polymer, small molecular, protein, peptide, cholesterol, polysaccharide, nano-crystal and hybrid materials are widely considered in drug delivery research. However, biomimetic and bioinspired materials and technology have shown promising results for use in therapeutics, due to their high biocompatibility and reduced immunogenicity. Such materials include dopamine, extracellular exosome, bile acids, ionic liquids, and red blood cell. This book covers each of these materials in detail, reviewing their potential and usage in drug delivery. As such, this book will be a great source of information for biomaterials scientists, biomedical engineers and those working in pharmaceutical research. Explores latest developments for a broad range of bioinspired and biomimetic materials for drug delivery applications Helps researchers overcome the challenges of biocompatibility and immunogenicity in drug development Provides both theoretical and practical knowledge in regards to materials characterization and use in a range of drugs

The End of Plagues

The End of Plagues Book
Author : John Rhodes
Publisher : St. Martin's Press
Release : 2013-09-24
ISBN : 1137381310
Language : En, Es, Fr & De

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Book Description :

At the turn of the twentieth century, smallpox claimed the lives of two million people per year. By 1979, the disease had been eradicated and victory was declared across the globe. Yet the story of smallpox remains the exception, as today a host of deadly contagions, from polio to AIDS, continue to threaten human health around the world. Spanning three centuries, The End of Plagues weaves together the discovery of vaccination, the birth and growth of immunology, and the fight to eradicate the world's most feared diseases. From Edward Jenner's discovery of vaccination in 1796, to the early nineteenth-century foundling voyages in which chains of orphans, vaccinated one by one, were sent to colonies around the globe, to the development of polio vaccines and the stockpiling of smallpox as a biological weapon in the Cold War, world-renown immunologist John Rhodes charts our fight against these plagues, and shows how vaccinations gave humanity the upper hand. Today, aid groups including the Bill and Melinda Gates Foundation and the World Health Organization have made the eradication of polio a priority, and Rhodes takes us behind the scenes to witness how soon we may be celebrating the eradication of polio.

Encyclopedia of Agriculture and Food Systems

Encyclopedia of Agriculture and Food Systems Book
Author : Anonim
Publisher : Elsevier
Release : 2014-07-29
ISBN : 0080931391
Language : En, Es, Fr & De

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Book Description :

Encyclopedia of Agriculture and Food Systems, Second Edition addresses important issues by examining topics of global agriculture and food systems that are key to understanding the challenges we face. Questions it addresses include: Will we be able to produce enough food to meet the increasing dietary needs and wants of the additional two billion people expected to inhabit our planet by 2050? Will we be able to meet the need for so much more food while simultaneously reducing adverse environmental effects of today’s agriculture practices? Will we be able to produce the additional food using less land and water than we use now? These are among the most important challenges that face our planet in the coming decades. The broad themes of food systems and people, agriculture and the environment, the science of agriculture, agricultural products, and agricultural production systems are covered in more than 200 separate chapters of this work. The book provides information that serves as the foundation for discussion of the food and environment challenges of the world. An international group of highly respected authors addresses these issues from a global perspective and provides the background, references, and linkages for further exploration of each of topics of this comprehensive work. Addresses important challenges of sustainability and efficiency from a global perspective. Takes a detailed look at the important issues affecting the agricultural and food industries today. Full colour throughout.

Small Animal Infectious Disease An Issue of Veterinary Clinics of North America Small Animal Practice

Small Animal Infectious Disease  An Issue of Veterinary Clinics of North America  Small Animal Practice Book
Author : Annette L. Litster
Publisher : Elsevier Health Sciences
Release : 2019-05-08
ISBN : 032367867X
Language : En, Es, Fr & De

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Book Description :

This issue of Veterinary Clinics: Small Animal Practice, edited by Dr. Annette Litster, is devoted to Small Animal Infectious Disease. Topics in this issue include: The dynamic nature of infectious disease risk in the 21st century: How dog transport impacts prevalence patterns; Dog transport and infectious disease risk: an international perspective; Effect of dog transport on high-risk infectious diseases (e.g. TVT, rabies etc.); H3N8 and H3N2; Feline panleukopenia: a re-emergent disease; Canine Lyme disease immunology; Canine leptospirosis diagnostics; Canine ehrlichiosis in the USA; Cutaneous and Renal Glomerular Vasculopathy (CRGV; Alabama Rot); Vector borne disease panel diagnostics; Feline vector-borne diseases; Canine brucellosis; and Current preventative strategies for rabies.

Frontiers in Anti Infective Agents Volume 5

Frontiers in Anti Infective Agents  Volume 5 Book
Author : Parvesh Singh,Vipan Kumar ,Rajshekhar Karpoormath
Publisher : Bentham Science Publishers
Release : 2021-09-14
ISBN : 9814998400
Language : En, Es, Fr & De

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Book Description :

Anti-infective agents are a distinct class of pharmacologically important molecules that has served mankind in different capacities to combat life-threating pathologic conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial and urinary anti-infective agents. However, evolutionary changes, adaptations and development of pathogenic microorganisms strains the therapeutic efficacy of these drugs thus limiting their clinical utility over the years. Frontiers in Anti-Infective Agents Volume 5 is a collection of notable research efforts, successful anti-infective drug development programmes and a comprehensive overview of the successes and failures of recent clinical trials in this domain. The volume covers interesting topics: 1) the treatment of acute wounds with the vikut® formula, 2) anti-infective treatment of ocular diseases and 3) sars-cov vaccine development and antimicrobial therapy for SARS symptoms. A chapter summarizing recent anti-infective approaches rounds up the contents of this volume. This volume is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.