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Unraveling The Complexities Of Metastasis

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Unraveling the Complexities of Metastasis

Unraveling the Complexities of Metastasis Book
Author : Ammad Ahmad Farooqi,Muhammad Zahid Qureshi,Uteuliyev Yerzhan Sabitaliyevi
Publisher : Academic Press
Release : 2020-09-15
ISBN : 9780128217894
Language : En, Es, Fr & De

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Book Description :

Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism. This book is a valuable source for cancer researchers, medical doctors and several members of biomedical field who need to understand better the complex mechanism of metastasis. Explains the mechanism of metastasis from basic to advanced level through easy and comprehensive chapters written by internationally distinguished researchers Provides simplified version of important process of metastasis for the readers to comprehend the latest advancements made in the field Presents colorful diagrams to make different aspects of scientifically difficult topics easier for young researchers and new-comers in the field of cancer metastasis

Molecular and Cellular Basis of Metastasis Road to Therapy

Molecular and Cellular Basis of Metastasis  Road to Therapy Book
Author : Anonim
Publisher : Academic Press
Release : 2016-09-03
ISBN : 0128041587
Language : En, Es, Fr & De

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Book Description :

Molecular and Cellular Basis of Metastasis: Road to Therapy, the latest in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, with this volume covering the molecular and cellular basis of metastasis. Presents groundbreaking information on the molecular and cellular basis of metastasis Provides information on cancer research Outstanding and original reviews Suitable for both researchers and students

ICRDB Cancergram

ICRDB Cancergram Book
Author : Anonim
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download ICRDB Cancergram book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Metastasis Research Protocols

Metastasis Research Protocols Book
Author : Susan A. Brooks,Udo Schumacher
Publisher : Springer Science & Business Media
Release : 2001
ISBN : 1592591361
Language : En, Es, Fr & De

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Book Description :

Although ninety percent of fatal cancer cases involve the spread of a primary tumor, the formation of metastases is still a poorly understood, complex process and a significant problem in the treatment of cancer patients. In Metastasis Research Protocols, leading international investigators describe the key methods needed to investigate why and how metastasis occurs. Volume I of this two-volume set, Analysis of Cells and Tissues, presents a comprehensive collection of established and leading-edge techniques for analyzing the expression of key molecules and for examining their production at the genetic level. The work focuses on the analysis and mapping of molecules produced by cells and tissues, and on the molecular biology underlying their expression. The traditional methods range from the histopathological and the immunocytochemical to SDS-PAGE, Western blotting, and enzyme zymography. Newer and more specialized techniques for analyzing the genetic aspects of metastasis include in situ hybridization to localize mRNAs, FISH, CGH, methylation analysis of CpG islands, RT-PCR, and differential display. The second volume of this set, Analysis of Cell Behavior In Vitro and In Vivo, moves to the level of living cells and tissues to present methodologies applicable to examining metastatic behavior in vitro and in the whole animal. Comprehensive and authoritative, the two volumes of Metastasis Research Protocols constitute a gold-standard collection of readily reproducible methods for understanding the metastatic cascade-first at the cellular and molecular levels, then at the level of the whole organism-responsible for the spread of cancer and for developing novel strategies to combat its spread.

Metastasis

Metastasis Book
Author : Lalage Wakefield,Kent W. Hunter
Publisher : IOS Press
Release : 2007
ISBN : 9781586037536
Language : En, Es, Fr & De

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Book Description :

"Metastasis is the most dreaded aspect of the carcinogenic process. More than ninety percent of all cancer deaths are attributable to the consequences of the primary tumor successfully colonizing distant organs. Unlike the situation with colon cancer, a patient with breast cancer can never be considered cured, since as many as a third of breast cancer patients who have apparently curative surgery for their primary tumors ultimately relapse with metastatic disease, sometimes decades later. Much effort is now devoted to understanding this process of metastasis, and finding ways to predict and prevent its occurrence. This publication covers recent advances in the field, specifically as they relate to breast cancer. The availability of new tools and technological approaches has prompted a reconsideration of the very definition of a metastasis. Furthermore, a number of commonly held myths are being explored and a new definition of a metastasis, with important implications for clinical staging, is being proposed. Also, a novel conceptual framework for cancer progression based on the system-level dynamics of regulatory networks is presented and the role of chemokines in mediating some of the evolving transactional processes between tumor and stroma is being reviewed."

Cancer Metastasis

Cancer Metastasis Book
Author : Volker Schirrmacher,Reinhard Schwartz-Albiez
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 364274236X
Language : En, Es, Fr & De

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Book Description :

These are the Proceedings of the 2nd International Metastasis Congress of the Metastasis Research Society which took place in the town hall (Stadthalle) of Heidelberg, FRG, in September, 1988. This first Metastasis Congress in the FRG was organized in conjunction with the German Association of Cancer Research (SEK) of the German Cancer Society. The congress topic generated tremendous interest and attracted about 400 scientists from 22 countries. Most participants came from Europe, Israel, and the United States. Why did we organize the Metastasis Congress? Only about 50% of all people who develop some form of cancer are curable. Despite improved patient care and increasingly innovative and effective techniques for diagnosing and treating primary cancers, the development of secondary cancer colonies, i. e. , metastasis, can not be prevented and is the major cause of death. In the Federal Republic of Germany there are still as many as 160 000 cancer patients per year who succumb to their disease, often after periods of terrible suffering, and this overall figure is not improving. Partly because of the complexity of the process, basic research on metastasis has lagged behind other disciplines such as carcino genesis and cancer genetics. Metastasis formation involves the ability of malig nant cells to invade adjacent tissue and to penetrate into lymphatic or blood circulatory systems, or both, and to spread to near or distant sites to form new tumor colonies. Meanwhile, research on metastasis is receiving much attention.

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2009-08
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Unravelling Cancer Signaling Pathways A Multidisciplinary Approach

Unravelling Cancer Signaling Pathways  A Multidisciplinary Approach Book
Author : Kakoli Bose,Pradip Chaudhari
Publisher : Springer Nature
Release : 2019-11-25
ISBN : 9813298162
Language : En, Es, Fr & De

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Book Description :

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.

Scientific Foundations of Surgery

Scientific Foundations of Surgery Book
Author : James Kyle,Larry C. Carey
Publisher : Unknown
Release : 1989
ISBN : 9780815152422
Language : En, Es, Fr & De

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Book Description :

Download Scientific Foundations of Surgery book written by James Kyle,Larry C. Carey, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pain

Pain Book
Author : Nursing Now
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Pain book written by Nursing Now, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Scientific Report

Scientific Report Book
Author : Scripps Research Institute
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Scientific Report book written by Scripps Research Institute, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pediatric Radiation Oncology

Pediatric Radiation Oncology Book
Author : Edward C. Halperin
Publisher : Raven Press (ID)
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The definitive text and reference on pediatric radiation oncology is now in its thoroughly revised and updated Fourth Edition. This edition features a brand-new section on intensity modulated radiation therapy (IMRT), detailed information on three-dimensional treatment planning, and diagrams showing three-dimensional treatment plans for brain tumors, retinoblastoma, sarcomas, and neuroblastoma. The authors review the most recent clinical trials on management of leukemia, supratentorial and infratentorial brain tumors, retinoblastoma, neuroblastoma, Hodgkin's disease, non-Hodgkin's lymphoma, Ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, and Wilms' tumor. This edition also includes new information on the late effects of cancer treatment and the risk of treatment-induced secondary malignant neoplasms.

Internal Medicine for Dentistry

Internal Medicine for Dentistry Book
Author : Donald Kaye
Publisher : Mosby Incorporated
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Ultrasound in Liquid and Solid Metals focuses on the effect of intensive ultrasound on metals, including the analysis of the development of cavitation and acoustic flows in melts, mechanism of metals' spraying and crystallization, the formation of dislocation structure in crystals, diffusion, phase transformation, and plastic deformation. Physical fundamentals of intensive ultrasound effects are covered, and detailed discussions are presented on the engineering principles of equipment and material design for the practical use of ultrasound in the refining of melts, crystallization of ingots and molds, pulverization, plating, pressure working of metals, surface strengthening, and other processes.

Journal of Cellular Physiology

Journal of Cellular Physiology Book
Author : Anonim
Publisher : Unknown
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of Cellular Physiology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America Book
Author : National Academy of Sciences (U.S.)
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Proceedings of the National Academy of Sciences of the United States of America book written by National Academy of Sciences (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Kansas Veterinarian

The Kansas Veterinarian Book
Author : Anonim
Publisher : Unknown
Release : 1967
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Vols. for 1970- include an annual issue with title: Convention issue.

The Journal of Immunology

The Journal of Immunology Book
Author : Anonim
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Genetics Abstracts

Genetics Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Genetics Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Adult Chest Surgery 2nd edition

Adult Chest Surgery  2nd edition Book
Author : David J. Sugarbaker,Raphael Bueno,Yolanda Colson,Michael Jaklitsch,Mark J. Krasna,Steven Mentzer
Publisher : McGraw Hill Professional
Release : 2014-07-22
ISBN : 0071781900
Language : En, Es, Fr & De

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Book Description :

The most authoritative, comprehensive, and clinically focused guide to operative thoracic surgery--updated with the latest techniques and technologies Adult Chest Surgery is a thorough, hands-on guide to the modern practice of general thoracic surgery. Broad in scope and straightforward in style and presentation, this classic is an outstanding reference for any clinician in need of a comprehensive description of the clinical nature of general thoracic surgery. Like its award-winning predecessor, the second edition of Adult Chest Surgery focuses on providing concise descriptions of current techniques and surgical principles for the most common thoracic surgical problems encountered in the clinic and the operating room. This edition is enhanced by 40 new chapters devoted to a range of topics including new endoscopic techniques for antireflux surgery; percutaneous thoracic tumor ablation; peroral esophageal myotomy; robotic techniques for lobectomy, esophagectomy, and thymectomy; and other new minimally invasive approaches to standard thoracic resections. It is also enriched by more than 250 new detailed illustrations of procedures, bringing the total number to 850. Adult Chest Surgery features a logical organization based on anatomy, and each section has an overview chapter, which summarizes the relevant anatomy, pathophysiology, and diagnostic and procedural options. Throughout, operations and diagnostic procedures are highlighted in succinct, illustrated technique chapters.