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Translational Bioinformatics In Healthcare And Medicine

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Translational Bioinformatics in Healthcare and Medicine

Translational Bioinformatics in Healthcare and Medicine Book
Author : Anonim
Publisher : Academic Press
Release : 2021-05-01
ISBN : 0323898904
Language : En, Es, Fr & De

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Book Description :

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. Covers recent advancements in translational bioinformatics and its healthcare applications Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content

Translational Bioinformatics Applications in Healthcare

Translational Bioinformatics Applications in Healthcare Book
Author : Khalid Raza,Nilanjan Dey
Publisher : CRC Press
Release : 2021-04-20
ISBN : 1000375161
Language : En, Es, Fr & De

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Book Description :

Translational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19–related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformatics Presents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics. Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and health informatics. Nilanjan Dey is an Associate Professor, the Department of Computer Science and Engineering, JIS University, Kolkata, India. His research interests include medical imaging, machine learning, computer-aided diagnosis, and data mining.

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine Book
Author : Qing Yan
Publisher : Academic Press
Release : 2017-04-18
ISBN : 0128043881
Language : En, Es, Fr & De

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Book Description :

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine Presents a problem-solving oriented methodology to deal with practical problems in various applications Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field

Biomedical Informatics Information Systems in Medicine and Health

Biomedical Informatics  Information Systems in Medicine and Health Book
Author : Cole Webb
Publisher : Unknown
Release : 2020-09-08
ISBN : 9781632428790
Language : En, Es, Fr & De

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Book Description :

Biomedical informatics is a field of information engineering that has applications in healthcare, particularly in the management and use of healthcare information. It is an interdisciplinary study that involves the design, adoption, development and IT-based innovations in healthcare services planning, delivery and management. Some of the tools of biomedical informatics are information and communication systems, computers, clinical guidelines, etc. It has applications in the areas of clinical medicine, pharmacy, nursing, public health, occupational therapy, biomedical research and physical therapy, among others. Some of the sub-fields of biomedical informatics are pathology informatics, imaging informatics, community health informatics, consumer health informatics, etc. Translational bioinformatics is an emerging field that integrates bio-statistics, molecular bioinformatics, clinical informatics and statistical genetics. It strives to identify the linkages between biological and clinical information, and enable better approaches to the study and treatment of diseases. This book explores all the important aspects of biomedical informatics in the present day scenario. The various studies that are constantly contributing towards advancing technologies and evolution of this field are examined in detail. The readers would gain knowledge that would broaden their perspective about the use of information systems in medicine and health.

Translational Informatics in Smart Healthcare

Translational Informatics in Smart Healthcare Book
Author : Bairong Shen
Publisher : Springer
Release : 2017-09-15
ISBN : 9811057176
Language : En, Es, Fr & De

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Book Description :

This book is about the transformation of the biomedical information to smart healthcare, the chapters are designed to discuss the health associated factors such as genetics, lifestyle, nutrition and environmental factors. The interactions of these factors and the informatics for the analyses of their effects on health are also covered. The era of aging is approaching and the P4 (predictive, preventive, personalized and participatory) medicine paradigm is becoming practical and reality. According to the Kondratiev's long wave theory, IT (information technology) and health will be the next technological revolution for the new economic cycle. This book is written for biomedical informatics scientists, clinicians, health practitioners and researchers, etc.

National Library of Medicine Programs and Services

National Library of Medicine Programs and Services Book
Author : National Library of Medicine (U.S.)
Publisher : Unknown
Release : 2011
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download National Library of Medicine Programs and Services book written by National Library of Medicine (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Translational Biomedical Informatics

Translational Biomedical Informatics Book
Author : Bairong Shen,Haixu Tang,Xiaoqian Jiang
Publisher : Springer
Release : 2016-10-31
ISBN : 9811015031
Language : En, Es, Fr & De

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Book Description :

This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

Translational Bioinformatics and Its Application

Translational Bioinformatics and Its Application Book
Author : Dong-Qing Wei,Yilong Ma,William C.S. Cho,Qin Xu,Fengfeng Zhou
Publisher : Springer
Release : 2017-03-31
ISBN : 9402410457
Language : En, Es, Fr & De

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Book Description :

This book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides clinical information, which can then be applied. Filling the gap between clinic research and informatics, the book is a valuable resource for human geneticists, clinicians, health educators and policy makers, as well as graduate students majoring in biology, biostatistics, and bioinformatics.

Global Healthgrid

Global Healthgrid Book
Author : Tony Solomonides
Publisher : IOS Press
Release : 2008
ISBN : 1586038745
Language : En, Es, Fr & De

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Book Description :

HealthGrid 2008 is the sixth conference in this series of open forums for the integration of grid technologies and its applications in the biomedical, medical and biological domains to pave the path to an international research area in healthgrids. The main objective of the HealthGrid conference and the HealthGrid Association is the exchange and discussion of ideas, technologies, solutions and requirements that interest the grid and the life-sciences communities to foster the integration of grids into health. Subjects in this publication reflect the diversity of mature practice: Advancing Virtual Communities, offering a glimpse of the kind of communities that are brought together by means of collaboration grids; Public Health Informatics, exploring the diffusion of grid concepts and technologies in health informatics; Translational Bioinformatics, the contact point between medicine, healthcare and genomics; and Knowledge Management and Decision Support, one direction that is confidently expected to grow as the synergy of grids and 'evidence-based practice' in healthcare is exploited.

Bioinformatics of Human Proteomics

Bioinformatics of Human Proteomics Book
Author : Xiangdong Wang
Publisher : Springer Science & Business Media
Release : 2013-01-26
ISBN : 9400758111
Language : En, Es, Fr & De

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Book Description :

“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.

Application of Clinical Bioinformatics

Application of Clinical Bioinformatics Book
Author : Xiangdong Wang,Christian Baumgartner,Denis C. Shields,Hong-Wen Deng,Jacques S Beckmann
Publisher : Springer
Release : 2016-03-31
ISBN : 9401775435
Language : En, Es, Fr & De

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Book Description :

This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.

Health Informatics for Medical Librarians

Health Informatics for Medical Librarians Book
Author : Ana D. Cleveland,Donald B. Cleveland
Publisher : Neal Schuman Pub
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Written specifically for information professionals, this text helps you grasp the fundamentals of a rapidly emerging field and describes how medical libraries can be essential players in the health informatics revolution. The book includes discussion of the history, role, and infrastructure of medical informatics as well as its impact on access to medical information and the culture and quality of medical care. From data and information processing to database management, telecommunications and networks, computer-aided instruction, and special technologies like wearable computers, you'll find thorough information on medical knowledge and the use of information technology tools in the health sciences. All major arenas--including nursing, pharmaceutical, dental, public health, hospital, and veterinary informatics--are considered in detail. A must-have for every medical or health library and information center, this is also an ideal text for undergraduate or graduate-level courses in biomedical information management.

Human Genome Informatics

Human Genome Informatics Book
Author : Christophe Lambert,Darrol Baker,George P. Patrinos
Publisher : Academic Press
Release : 2018-08-02
ISBN : 0128134313
Language : En, Es, Fr & De

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Book Description :

Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field. Provides an overview of the most commonly used electronic tools to translate genomic information Brings an update on the existing human genomic databases that directly impact genome interpretation Summarizes and comparatively analyzes interpretation methods of whole genome data and their application in genomic medicine

Translational Informatics

Translational Informatics Book
Author : Philip R.O. Payne,Peter J. Embi
Publisher : Springer
Release : 2014-08-23
ISBN : 1447146468
Language : En, Es, Fr & De

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Book Description :

Integrative and translational methodologies and frameworks have transformed modern biomedical research and the delivery of clinical care. This shift has been manifested in a number of ways, including the rapid growth and increasing availability of high-throughput bio-molecular instrumentation and analysis platforms, innovative clinical research programs intended to accelerate knowledge translation, and initial efforts to deliver personalized healthcare informed by the genomic profiles of patients. A common theme of reports and publications concerned with such transformative changes in the biomedical and healthcare domains is concerned with the challenges and opportunities related to the collection, management, integration, analysis, and dissemination of large-scale, heterogeneous biomedical data sets. In particular, the absence of well-established and adopted theoretical and practical frameworks intended to address such needs is a major impediment to the realization of translational and knowledge-driven healthcare, in which the best possible scientific evidence is used to inform the care of every patient. In this vacuum, the development of integrative clinical or translational research paradigms is significantly limited by the propagation of both data and expertise silos. This book details for the first time the current state of this extremely potent area of healthcare innovation and policy and defines the interaction between clinical/translational science and biomedical informatics.​

MEDINFO 2017 Precision Healthcare Through Informatics

MEDINFO 2017  Precision Healthcare Through Informatics Book
Author : A.V. Gundlapalli,M.-C. Jaulent,D. Zhao
Publisher : IOS Press
Release : 2018-01-31
ISBN : 1614998302
Language : En, Es, Fr & De

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Book Description :

Medical informatics is a field which continues to evolve with developments and improvements in foundational methods, applications, and technology, constantly offering opportunities for supporting the customization of healthcare to individual patients. This book presents the proceedings of the 16th World Congress of Medical and Health Informatics (MedInfo2017), held in Hangzhou, China, in August 2017, which also marked the 50th anniversary of the International Medical Informatics Association (IMIA). The central theme of MedInfo2017 was "Precision Healthcare through Informatics", and the scientific program was divided into five tracks: connected and digital health; human data science; human, organizational, and social aspects; knowledge management and quality; and safety and patient outcomes. The 249 accepted papers and 168 posters included here span the breadth and depth of sub-disciplines in biomedical and health informatics, such as clinical informatics; nursing informatics; consumer health informatics; public health informatics; human factors in healthcare; bioinformatics; translational informatics; quality and safety; research at the intersection of biomedical and health informatics; and precision medicine. The book will be of interest to all those who wish to keep pace with advances in the science, education, and practice of biomedical and health informatics worldwide.

Handbook of Personalized Medicine

Handbook of Personalized Medicine Book
Author : Ioannis S. Vizirianakis
Publisher : CRC Press
Release : 2014-02-12
ISBN : 9814411205
Language : En, Es, Fr & De

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Book Description :

This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Healthcare and Big Data Management

Healthcare and Big Data Management Book
Author : Bairong Shen
Publisher : Springer
Release : 2017-10-20
ISBN : 981106041X
Language : En, Es, Fr & De

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Book Description :

The book addresses the interplay of healthcare and big data management. Thanks to major advances in big data technologies and precision medicine, healthcare is now becoming the new frontier for both scientific research and economic development. This volume covers a range of aspects, including: big data management for healthcare; physiological and gut microbiota – data collection and analysis; big data standardization and ontology; and personal data privacy and systems level modeling in the healthcare context. The book offers a valuable resource for biomedical informaticians, clinicians, health practitioners and researchers alike.

Informatics Education in Healthcare

Informatics Education in Healthcare Book
Author : Eta S. Berner
Publisher : Springer Science & Business Media
Release : 2013-09-02
ISBN : 1447140788
Language : En, Es, Fr & De

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Book Description :

This book reviews and defines the current state of the art for informatics education in medicine and health care. This field has undergone considerable change as the field of informatics itself has evolved. Twenty years ago almost the only individuals involved in health care who had even heard the term “informatics” were those who identified themselves as medical or nursing informaticians. Today, we have a variety of subfields of informatics including not just medical and nursing informatics, but informatics applied to specific health professions (such as dental or pharmacy informatics), as well as biomedical informatics, bioinformatics and public health informatics. The book addresses the broad range of informatics education programs available today. The Editor and experienced internationally recognized informatics educators who have contributed to this work have made the tacit knowledge explicit and shared some of the lessons they have learned. This book therefore represents the key reference for all involved in the informatics education whether they be trainers or trainees.

Biomedical Informatics in Translational Research

Biomedical Informatics in Translational Research Book
Author : Hai Hu,Richard J. Mural,Michael N. Liebman
Publisher : Artech House
Release : 2008
ISBN : 159693039X
Language : En, Es, Fr & De

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Book Description :

This trailblazing resource on biomedical informatics provides medical researchers with innovative techniques for integrating and federating data from clinical and molecular studies. This volume helps researchers manage data, expedite their efforts, and make the most of targeted basic research.

Evolution of Translational Omics

Evolution of Translational Omics Book
Author : Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials
Publisher : National Academies Press
Release : 2012-09-13
ISBN : 0309224187
Language : En, Es, Fr & De

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Book Description :

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.