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Translational Bioinformatics And Systems Biology Methods For Personalized Medicine

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Translational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine Book
Author : Qing Yan
Publisher : Academic Press
Release : 2017-04-18
ISBN : 0128043881
Language : En, Es, Fr & De

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Book Description :

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine Presents a problem-solving oriented methodology to deal with practical problems in various applications Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field

Bioinformatics and Biomarker Discovery

Bioinformatics and Biomarker Discovery Book
Author : Francisco Azuaje
Publisher : John Wiley & Sons
Release : 2011-08-24
ISBN : 111996430X
Language : En, Es, Fr & De

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Book Description :

This book is designed to introduce biologists, clinicians and computational researchers to fundamental data analysis principles, techniques and tools for supporting the discovery of biomarkers and the implementation of diagnostic/prognostic systems. The focus of the book is on how fundamental statistical and data mining approaches can support biomarker discovery and evaluation, emphasising applications based on different types of "omic" data. The book also discusses design factors, requirements and techniques for disease screening, diagnostic and prognostic applications. Readers are provided with the knowledge needed to assess the requirements, computational approaches and outputs in disease biomarker research. Commentaries from guest experts are also included, containing detailed discussions of methodologies and applications based on specific types of "omic" data, as well as their integration. Covers the main range of data sources currently used for biomarker discovery Covers the main range of data sources currently used for biomarker discovery Puts emphasis on concepts, design principles and methodologies that can be extended or tailored to more specific applications Offers principles and methods for assessing the bioinformatic/biostatistic limitations, strengths and challenges in biomarker discovery studies Discusses systems biology approaches and applications Includes expert chapter commentaries to further discuss relevance of techniques, summarize biological/clinical implications and provide alternative interpretations

Handbook of Personalized Medicine

Handbook of Personalized Medicine Book
Author : Ioannis S. Vizirianakis
Publisher : CRC Press
Release : 2014-02-12
ISBN : 9814411205
Language : En, Es, Fr & De

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Book Description :

This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Information Resources in Toxicology

Information Resources in Toxicology Book
Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
Publisher : Academic Press
Release : 2020-05-16
ISBN : 0128137258
Language : En, Es, Fr & De

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Book Description :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources. Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles. Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals. Explores recent internet trends, web-based databases, and software tools in a section on the online environment. Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents. Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field.

Advances in Biotechnology Research and Application 2011 Edition

Advances in Biotechnology Research and Application  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464921040
Language : En, Es, Fr & De

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Book Description :

Advances in Biotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biotechnology. The editors have built Advances in Biotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Technology for Smart Futures

Technology for Smart Futures Book
Author : Mohammad Dastbaz,Hamid Arabnia,Babak Akhgar
Publisher : Springer
Release : 2017-09-05
ISBN : 3319601377
Language : En, Es, Fr & De

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Book Description :

This book explores the nexus of Sustainability and Information Communication Technologies that are rapidly changing the way we live, learn, and do business. The monumental amount of energy required to power the Zeta byte of data traveling across the globe’s billions of computers and mobile phones daily cannot be overstated. This ground-breaking reference examines the possibility that our evolving technologies may enable us to mitigate our global energy crisis, rather than adding to it. By connecting concepts and trends such as smart homes, big data, and the internet of things with their applications to sustainability, the authors suggest that emerging and ubiquitous technologies embedded in our daily lives may rightfully be considered as enabling solutions for our future sustainable development.

Translational Bioinformatics in Healthcare and Medicine

Translational Bioinformatics in Healthcare and Medicine Book
Author : Anonim
Publisher : Academic Press
Release : 2021-05-13
ISBN : 0323898904
Language : En, Es, Fr & De

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Book Description :

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. Covers recent advancements in translational bioinformatics and its healthcare applications Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content

Psychoneuroimmunology

Psychoneuroimmunology Book
Author : Qing Yan
Publisher : Springer
Release : 2016-10-03
ISBN : 3319451111
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of the cutting-edge discoveries and the systems approaches related to the multi-disciplinary field of psychoneuroimmunology (PNI), which may provide the scientific basis for mind-body relationships, and aid in the development of personalized medicine. Specifically, the book focuses on the systems biology studies of complex mechanisms, such as stress and inflammation. There is strong evidence supporting the close relationship between stress, inflammation, and disorders including obesity, cardiovascular disease, diabetes, skin diseases, and sleep disorders. As inflammation is a critical connection among different diseases, further elucidating this connection may contribute to the findings of systemic therapeutic targets. Translational medicine is also addressed, by applying PNI approaches in clinical practice. A major challenge in current bioscience is the translation of basic scientific discoveries into better clinical outcomes. With the understanding of the translational implications of PNI, integrative interventions can be applied to modulate stress responses and to promote healthier behaviors. As an important feature of this book, a broad overview of the PNI-associated integrative interventions is provided. These interventions include nutritional supplements, meditation, and other mind-body strategies. From basic concepts to systems methodologies, from theoretical sources to clinical applications, Psychoneuroimmunology contributes to the understanding and development of PNI toward the establishment of personalized and mind-body medicine.

EEG Brain Signal Classification for Epileptic Seizure Disorder Detection

EEG Brain Signal Classification for Epileptic Seizure Disorder Detection Book
Author : Sandeep Kumar Satapathy,Satchidananda Dehuri,Alok Kumar Jagadev,Shruti Mishra
Publisher : Academic Press
Release : 2019-02-10
ISBN : 0128174277
Language : En, Es, Fr & De

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Book Description :

EEG Brain Signal Classification for Epileptic Seizure Disorder Detection provides the knowledge necessary to classify EEG brain signals to detect epileptic seizures using machine learning techniques. Chapters present an overview of machine learning techniques and the tools available, discuss previous studies, present empirical studies on the performance of the NN and SVM classifiers, discuss RBF neural networks trained with an improved PSO algorithm for epilepsy identification, and cover ABC algorithm optimized RBFNN for classification of EEG signal. Final chapter present future developments in the field. This book is a valuable source for bioinformaticians, medical doctors and other members of the biomedical field who need the most recent and promising automated techniques for EEG classification. Explores machine learning techniques that have been modified and validated for the purpose of EEG signal classification using Discrete Wavelet Transform for the identification of epileptic seizures Encompasses machine learning techniques, providing an easily understood resource for both non-specialized readers and biomedical researchers Provides a number of experimental analyses, with their results discussed and appropriately validated

Bioinformatics for Diagnosis Prognosis and Treatment of Complex Diseases

Bioinformatics for Diagnosis  Prognosis and Treatment of Complex Diseases Book
Author : Bairong Shen
Publisher : Springer Science & Business Media
Release : 2013-11-25
ISBN : 9400779755
Language : En, Es, Fr & De

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Book Description :

The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases. The book covers both state of the art of bioinformatics methodologies and the examples for the identification of simple or network biomarkers. In addition, bioinformatics software tools and scripts are provided to the practical application in the study of complex diseases. The present state, the future challenges and perspectives were discussed. The book is written for biologists, biomedical informatics scientists and clinicians, etc. Dr. Bairong Shen is Professor and Director of Center for Systems Biology, Soochow University; he is also Director of Taicang Center for Translational Bioinformatics.

Encyclopedia of Biomedical Engineering

Encyclopedia of Biomedical Engineering Book
Author : Anonim
Publisher : Elsevier
Release : 2018-09-01
ISBN : 0128051442
Language : En, Es, Fr & De

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Book Description :

Encyclopedia of Biomedical Engineering is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field

Computational and Statistical Epigenomics

Computational and Statistical Epigenomics Book
Author : Andrew E. Teschendorff
Publisher : Springer
Release : 2015-05-12
ISBN : 940179927X
Language : En, Es, Fr & De

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Book Description :

This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key role in the personalized medicine of the future. In this book we introduce the reader to some of the most important computational and statistical methods for analyzing epigenomic data, with a special focus on DNA methylation. Topics include normalization, correction for cellular heterogeneity, batch effects, clustering, supervised analysis and integrative methods for systems epigenomics. This book will be of interest to students and researchers in bioinformatics, biostatistics, biologists and clinicians alike. Dr. Andrew E. Teschendorff is Head of the Computational Systems Genomics Lab at the CAS-MPG Partner Institute for Computational Biology, Shanghai, China, as well as an Honorary Research Fellow at the UCL Cancer Institute, University College London, UK.

Perspectives on Digital Pathology

Perspectives on Digital Pathology Book
Author : Marcial García-Rojo,Bernd Blobel,Arvydas Laurinavicius
Publisher : IOS Press
Release : 2012
ISBN : 1614990859
Language : En, Es, Fr & De

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Book Description :

Multimedia information and digital images are increasingly important in the field of healthcare, but establishing an adequate technological framework for their management, and workable international standards to ensure compatibility and interoperability, are crucial if they are to be employed effectively. This book presents the main research efforts of EURO-TELEPATH, an initiative of the European Corporation in Science and Technology (COST) Action, IC0604. This program began in November 2007, and ran until November 2011. Its aim was to develop the standards and solutions necessary to represent, interpret, browse and retrieve digital medical images, while preserving their diagnostic quality for clinical purposes, education and research. At the end of the project, the most relevant researchers in the field of digital pathology u many of whom had been active members of EURO-TELEPATH u were asked to contribute to a book which would compile the main research efforts of the European COST Action consortium. The book is divided into six parts. The first is an introduction to the instruments and activities of COST.This is followed by sections dealing with: the state-of-the-art in pathology; pathology business modeling; standards and specifications in pathology; the analysis, processing, retrieval and management of images; technology and automation in pathology; and strategic developments and emerging research. As well as being a comprehensive overview of the IC0604 COST program, the book includes a selection of papers from American and Japanese researchers working in the same field.

Foundations of Biomedical Knowledge Representation

Foundations of Biomedical Knowledge Representation Book
Author : Arjen Hommersom,Peter J.F. Lucas
Publisher : Springer
Release : 2016-01-07
ISBN : 3319280074
Language : En, Es, Fr & De

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Book Description :

Medicine and health care are currently faced with a significant rise in their complexity. This is partly due to the progress made during the past three decades in the fundamental biological understanding of the causes of health and disease at the molecular, (sub)cellular, and organ level. Since the end of the 1970s, when knowledge representation and reasoning in the biomedical field became a separate area of research, huge progress has been made in the development of methods and tools that are finally able to impact on the way medicine is being practiced. Even though there are huge differences in the techniques and methods used by biomedical researchers, there is now an increasing tendency to share research results in terms of formal knowledge representation methods, such as ontologies, statistical models, network models, and mathematical models. As there is an urgent need for health-care professionals to make better decisions, computer-based support using this knowledge is now becoming increasingly important. It may also be the only way to integrate research results from the different parts of the spectrum of biomedical and clinical research. The aim of this book is to shed light on developments in knowledge representation at different levels of biomedical application, ranging from human biology to clinical guidelines, and using different techniques, from probability theory and differential equations to logic. The book starts with two introductory chapters followed by 18 contributions organized in the following topical sections: diagnosis of disease; monitoring of health and disease and conformance; assessment of health and personalization; prediction and prognosis of health and disease; treatment of disease; and recommendations.

Pharmaceutical Sciences Breakthroughs in Research and Practice

Pharmaceutical Sciences  Breakthroughs in Research and Practice Book
Author : Management Association, Information Resources
Publisher : IGI Global
Release : 2016-12-28
ISBN : 1522517634
Language : En, Es, Fr & De

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Book Description :

The delivery of optimal pharmaceutical services to patients is a pivotal concern in the healthcare field. By examining current trends and techniques in the industry, processes can be maintained and improved. Pharmaceutical Sciences: Breakthroughs in Research and Practice provides comprehensive coverage of the latest innovations and advancements for pharmaceutical applications. Focusing on emerging drug development techniques and drug delivery for improved health outcomes, this book is ideally designed for medical professionals, pharmacists, researchers, academics, and upper-level students within the growing pharmaceutical industry.

Bioinformatics of Human Proteomics

Bioinformatics of Human Proteomics Book
Author : Xiangdong Wang
Publisher : Springer Science & Business Media
Release : 2013-01-26
ISBN : 9400758111
Language : En, Es, Fr & De

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Book Description :

“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.

Omics for Personalized Medicine

Omics for Personalized Medicine Book
Author : Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly
Publisher : Springer Science & Business Media
Release : 2013-10-14
ISBN : 8132211847
Language : En, Es, Fr & De

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Book Description :

“Omics for Personalized Medicine” will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.

Translational Biotechnology

Translational Biotechnology Book
Author : Yasha Hasija
Publisher : Academic Press
Release : 2021-01-17
ISBN : 0128219734
Language : En, Es, Fr & De

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Book Description :

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Systems Biology

Systems Biology Book
Author : Nikolaus Rajewsky,Stefan Jurga,Jan Barciszewski
Publisher : Springer
Release : 2018-08-29
ISBN : 3319929674
Language : En, Es, Fr & De

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Book Description :

Many breakthroughs in experimental devices, advanced software, as well as analytical methods for systems biology development have helped shape the way we study DNA, RNA and proteins, on the genomic, transcriptional, translational and posttranslational level. This book highlights the comprehensive topics that encompass systems biology with enormous progress in the development of genome sequencing, proteomic and metabolomic methods in designing and understanding biological systems. Topics covered in this book include fundamentals of modelling networks, circuits and pathways, spatial and multi cellular systems, image-driven systems biology, evolution, noise and decision-making in single cells, systems biology of disease and immunology, and personalized medicine. Special attention is paid to epigenomics, in particular environmental conditions that impact genetic background. The breadth of exciting new data towards discovering fundamental principles and direct application of epigenetics in agriculture is also described. The chapter “Deciphering the Universe of RNA Structures and Trans RNA-RNA Interactions of Transcriptomes in vivo - from Experimental Protocols to Computational Analyses” is available open access under a CC BY 4.0 license via link.springer.com.

Biochemistry Biophysics and Molecular Chemistry

Biochemistry  Biophysics  and Molecular Chemistry Book
Author : Francisco Torrens,Debarshi Kar Mahapatra,A. K. Haghi
Publisher : CRC Press
Release : 2020-04-13
ISBN : 1000008320
Language : En, Es, Fr & De

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Book Description :

Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions provides the background needed in biophysics and molecular chemistry and offers a great deal of advanced biophysical knowledge. It emphasizes the growing interrelatedness of molecular chemistry and biochemistry, and acquaints one with experimental methods of both disciplines. This book addresses some of the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry. Topics include scientific integrity and ethics in the field; clinical translational research in cancer, diabetes, and cardiovascular disease; emerging drugs to treat neurodegenerative diseases; swine, avian, and human flu; the use of big data in artificial knowledge in the field; bioinformatic insights on molecular chemistry; and much more.