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Transition Metal Catalyzed Benzofuran Synthesis

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Transition Metal Catalyzed Benzofuran Synthesis

Transition Metal Catalyzed Benzofuran Synthesis Book
Author : Xiao-Feng Wu,Yahui Li
Publisher : Elsevier
Release : 2017-02-01
ISBN : 0128093706
Language : En, Es, Fr & De

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Book Description :

Transition Metal-Catalyzed Benzofuran Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series provides an overview of benzofuran, describing properties of these heterocycle compounds and the traditional synthetic procedures used for them. The book then explores catalyzed procedures for benzofuran synthesis in greater detail and depth than is currently available in published review articles. This volume is part of the short series authored by Xiao-Feng Wu that summarizes recent achievements on heterocycle synthesis with transition metals as catalysts, with each volume dedicated to one heterocycle compound. Offers a brief, focused review of this active research in benzofuran synthesis via transition metal catalysis Useful coverage of benzofuran properties and both intermolecular and intramolecular cyclization Volume Four in Elsevier’s short work series, Transition Metal-Catalyzed Heterocycles Synthesis Provides greater detail and depth than is currently available in published review articles

Transition Metal Catalyzed Benzofuran Synthesis

Transition Metal Catalyzed Benzofuran Synthesis Book
Author : Xiao Feng Wu
Publisher : Elsevier
Release : 2016-11-01
ISBN : 9780128093771
Language : En, Es, Fr & De

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Book Description :

"Transition Metal-Catalyzed Benzofuran Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series" provides an overview of benzofuran, describing properties of these heterocycle compounds and the traditional synthetic procedures used for them. The book then explores catalyzed procedures for benzofuran synthesis in greater detail and depth than is currently available in published review articles. This volume is part of the short series authored by Xiao-Feng Wu that summarizes recent achievements on heterocycle synthesis with transition metals as catalysts, with each volume dedicated to one heterocycle compound. Offers a brief, focused review of this active research in benzofuran synthesis via transition metal catalysisUseful coverage of benzofuran properties and both intermolecular and intramolecular cyclization Volume Four in Elsevier s short work series, "Transition Metal-Catalyzed Heterocycles Synthesis"Provides greater detail and depth than is currently available in published review articles"

Synthesis and Modification of Heterocycles by Metal Catalyzed Cross coupling Reactions

Synthesis and Modification of Heterocycles by Metal Catalyzed Cross coupling Reactions Book
Author : Tamás Patonay,Krisztina Kónya
Publisher : Springer
Release : 2016-06-15
ISBN : 3319326104
Language : En, Es, Fr & De

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Book Description :

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Transition Metal Catalyzed Heterocycle Synthesis Via C H Activation

Transition Metal Catalyzed Heterocycle Synthesis Via C H Activation Book
Author : Xiao-Feng Wu
Publisher : John Wiley & Sons
Release : 2016-03-07
ISBN : 3527338888
Language : En, Es, Fr & De

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Book Description :

Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.

Catalyzed Carbon Heteroatom Bond Formation

Catalyzed Carbon Heteroatom Bond Formation Book
Author : Andrei K. Yudin
Publisher : John Wiley & Sons
Release : 2010-12-01
ISBN : 3527633405
Language : En, Es, Fr & De

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Book Description :

Written by an experienced editor widely acclaimed within the scientific community, this book covers everything from oxygen to nitrogen functionalities. From the contents: * Palladium-Catalyzed Syntheses of Five-Membered Saturated Heterocycles * The Formation of Carbon-Sulfur and Carbon-Selenium Bonds by Substitution and Addition Reactions Catalyzed by Transition Metal Complexes * Palladium-Catalysis for Oxidative 1,2-Difunctionalization of Alkenes * Palladium-Catalyzed Formation of Aromatic Heterocycles * Rhodium-Catalyzed Amination of C-H-Bonds * Transition Metal-Catalyzed Synthesis of Heterocycles * Copper-Catalyzed Synthesis of Azoles * Palladium(II)-Catalyzed C-N Bond Formation Involving Aminopalladation of Aklenes * Carbon-Heteroatom Bond Formation by Rh(I)-Catalyzed Ring-Opening Reactions * Recent Advances in Homogeneous Gold Catalysis: Formation of Carbon-Heteroatom Bonds The result is an indispensable source of information for the strategic planning of the synthetic routes for organic, catalytic and medicinal chemists, as well as chemists in industry.

Advances in Transition Metal Mediated Heterocyclic Synthesis

Advances in Transition Metal Mediated Heterocyclic Synthesis Book
Author : Daniel Sole,Israel Fernandez
Publisher : Academic Press
Release : 2018-05-17
ISBN : 0128116528
Language : En, Es, Fr & De

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Book Description :

Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction). Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co). Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, this book is a valuable resource not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals. Helpfully organized by transformation type to stimulate the search for new synthetic processes Completely illustrated and written by global experts Includes thoughtfully selected strategies chosen by the editors to exemplify the state-of-the-art of the subject, including transition-metal reactions involving unsaturated systems, organopalladium chemistry, and metal-catalyzed C-H activation

Modern Heterocyclic Chemistry

Modern Heterocyclic Chemistry Book
Author : Julio Alvarez-Builla,Juan José Vaquero,José Barluenga
Publisher : John Wiley & Sons
Release : 2011
ISBN : 3527332014
Language : En, Es, Fr & De

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Book Description :

Download Modern Heterocyclic Chemistry book written by Julio Alvarez-Builla,Juan José Vaquero,José Barluenga, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry Book
Author : Anonim
Publisher : Academic Press
Release : 2019-03-19
ISBN : 0128174749
Language : En, Es, Fr & De

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Book Description :

Advances in Heterocyclic Chemistry, Volume 129 is the definitive series in the field—one of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive, updated release includes chapters on Metal-Catalyzed Direct Arylation of 1,2-Azoles, The Literature of Heterocyclic Chemistry, Part XVII, 2017, Pyrrolo-, Imidazoquinolines and Pyrroloquinazolines with a Bridgehead Nitrogen, Synthesis and Reactions of Arsole, Stibole, and Bismole, Advances in Synthesis and Chemistry of Aziridines, and more. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Heterocycles from Double Functionalized Arenes

Heterocycles from Double Functionalized Arenes Book
Author : Xiao-Feng Wu,Matthias Beller
Publisher : Royal Society of Chemistry
Release : 2015-02-02
ISBN : 1782623124
Language : En, Es, Fr & De

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Book Description :

The efficient synthesis of heterocycles has become one of the main branches in organic chemistry due to their use in the synthesis of natural products and pharmaceuticals. Current sythentic strategies based on C-H activation methodologies are met with many problems like harsh reaction conditions and low reaction efficiency. Double functionalized chemicals offer a perfect alternative for the synthesis of heterocycles. Heterocycles from Double-Functionalized Arenes starts with a short discussion on the importance of heterocycles and a brief introduction on the preparation of double-functionalized arenes. Specific chapters then look at five-membered heterocycles synthesis, six-membered heterocycles synthesis and macroheterocycles synthesis. This is the first book dedicated to the topic of transition metal catalyzed coupling reactions of double functionalized arenes in heterocycle synthesis and can be used as a handbook for senior researchers and as an introduction for organic chemistry students.

Noble Metal Noble Value

Noble Metal Noble Value Book
Author : Xiao-Feng Wu
Publisher : World Scientific
Release : 2016-06-24
ISBN : 1783269251
Language : En, Es, Fr & De

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Book Description :

Heterocyclic chemistry constitutes the largest branch of chemistry, covering almost two-thirds of literature in the field. In addition, around 90% of naturally-occurring molecules have heterocycles as their core structure. Therefore, as a central part of organic chemistry, the discovery of new methodologies in synthesizing heterocyclic compounds is essential to their continued application and development. Transition metal catalysts offer a low cost and often low toxicity pathway for heterocycles synthesis, while the use of noble metals represents an alternative form of experimentation which is discussed in the book. Noble Metals, Noble Value provides the first comprehensive analysis of the applications of the noble metals of ruthenium (Ru), rhodium (Rh) and palladium (Pd) catalysts in heterocycles synthesis. Pairs of chapters are dedicated to summarizing each of the metals when applied to either five- or six-membered heterocyclic syntheses. An introduction to the importance of heterocycles and possible procedures for the preparation of heterocyclic compounds is also given. With up to date research and findings, this review is excellently suited to academics and professionals in the field of chemistry, with a particular focus on the specialities of biological, catalytic and organic chemistry. Contents:Ru-Catalyzed Five-Membered Heterocycles SynthesisRuthenium Catalysis in the Synthesis of Six-Membered HeterocyclesRh-Catalyzed Five-Membered Heterocycle SynthesisRh-Catalyzed Six-Membered Heterocycles SynthesisPalladium-Catalyzed Synthesis of Five-Membered HeterocyclesPd-Catalyzed Six-Membered Heterocycles SynthesisPd-Catalyzed Synthesis of Sulfur- and Phosphorus-Containing Heterocycles via C-H ActivationPd-Catalyzed Heterocycles Synthesis in Ionic Liquids Readership: Academics and professionals in the field of chemistry, with a particular focus on the specialities of biological, catalytic and organic chemistry.

Applications of Transition Metal Catalysis in Drug Discovery and Development

Applications of Transition Metal Catalysis in Drug Discovery and Development Book
Author : Matthew L. Crawley,Barry M. Trost
Publisher : John Wiley & Sons
Release : 2012-07-03
ISBN : 0470631325
Language : En, Es, Fr & De

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Book Description :

This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.

Transition Metal Catalyzed Furans Synthesis

Transition Metal Catalyzed Furans Synthesis Book
Author : Xiao-Feng Wu
Publisher : Elsevier
Release : 2015-09-08
ISBN : 0128040726
Language : En, Es, Fr & De

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Book Description :

Transition Metal Catalyzed Furans Synthesis provides an overview of Furans, describing properties of these heterocycle compounds and covering traditional synthetic procedures for them. This book then explores catalyzed procedures for Furans synthesis in greater detail and depth then is currently available in published Reviews. Finally, this useful short work discusses natural products and bio-active compounds containing Furans, information of particular interest for their applications to medicinal and pharmaceutical chemistry. The short series Transition Metal Catalyzed Heterocycles Synthesis Series, authored by Xiao-Feng Wu, summarizes recent achievements on heterocycles synthesis with transition metal as the catalysts, with each volume dedicated to one heterocycle compound. Brief, focused review of this active research area, Furans synthesis via transition metal catalysis Useful coverage of furans properties and procedures, as well as relevant Furan-containing natural products First volume in short work series, "Transition Metal-Catalyzed Heterocycles Synthesis"

Transition Metal Catalyzed Carbonylative Synthesis of Heterocycles

Transition Metal Catalyzed Carbonylative Synthesis of Heterocycles Book
Author : Xiao-Feng Wu,Matthias Beller
Publisher : Springer
Release : 2015-12-14
ISBN : 3319249630
Language : En, Es, Fr & De

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Book Description :

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Multicomponent Reactions

Multicomponent Reactions Book
Author : K.L. Ameta, Ph.D.,Anshu Dandia
Publisher : CRC Press
Release : 2017-09-20
ISBN : 1498734197
Language : En, Es, Fr & De

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Book Description :

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.

Organic Reaction Mechanisms 2018

Organic Reaction Mechanisms 2018 Book
Author : Mark G. Moloney
Publisher : John Wiley & Sons
Release : 2021-08-17
ISBN : 1119532000
Language : En, Es, Fr & De

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Book Description :

Organic Reaction Mechanisms 2018, the 54th annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2018. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements Transition Metal Coupling Radical Reactions An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.

Transition Metal Mediated Aromatic Ring Construction

Transition Metal Mediated Aromatic Ring Construction Book
Author : Ken Tanaka
Publisher : John Wiley & Sons
Release : 2013-07-09
ISBN : 111862999X
Language : En, Es, Fr & De

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Book Description :

State-of-the-science methods, synthetic routes, andstrategies to construct aromatic rings The development of new reactions for the synthesis of aromaticcompounds is a highly active research area in organic synthesis,providing new functional organic materials, functional reagents,and biologically active compounds. Recently, significant advancesin transition-metal-mediated reactions have enabled the efficientand practical construction of new aromatic rings with usefulproperties and applications. This book draws together and reviewsall the latest discoveries and methods in transition-metal-mediatedreactions, offering readers promising new routes to design andconstruct complex aromatic compounds. Integrating metal catalysis with aromatic compound synthesis,Transition-Metal-Mediated Aromatic Ring Construction offersa practical guide to the methods, synthetic routes, and strategiesfor constructing aromatic compounds. The book's five partsexamine: [2+2+2], [2+2+1], and related cycloaddition reactions [4+2], [3+2], and related cycloaddition reactions Electrocyclization reactions Coupling and addition reactions Other important transformations, including methathesisreactions and skeletal rearrangement reactions Edited by Ken Tanaka, an internationally recognized expert inthe field of transition-metal catalysis, the book features authorswho are leading pioneers and researchers in synthetic reactions.Their contributions reflect a thorough review and analysis of theliterature as well as their own firsthand laboratory experiencedeveloping new aromatic compounds. All chapters end with a summary and outlook, setting forth newavenues of research and forecasting new discoveries. There are alsoreferences at the end of each chapter, guiding readers to importantoriginal research reports and reviews. In summary, Transition-Metal-Mediated Aromatic RingConstruction offers synthetic chemists a promising new avenuefor the development of important new aromatic compounds with abroad range of applications.

Heterocyclic Chemistry in Drug Discovery

Heterocyclic Chemistry in Drug Discovery Book
Author : Jie Jack Li
Publisher : John Wiley & Sons
Release : 2013-04-26
ISBN : 1118354435
Language : En, Es, Fr & De

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Book Description :

Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls. Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features: Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery Step-by-step descriptions of synthetic methods and practical techniques Examination of the physical properties for each heterocycle, including NMR data and quantum calculations Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.

Metalation of Azoles and Related Five Membered Ring Heterocycles

Metalation of Azoles and Related Five Membered Ring Heterocycles Book
Author : Gordon W. Gribble
Publisher : Springer
Release : 2012-07-09
ISBN : 364231791X
Language : En, Es, Fr & De

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Book Description :

T. L.S. Kishbaugh: Metalation of Pyrrole.- K.-S. Yeung: Furans and Benzofurans.- P. E. Alford: Lithiation-Based and Magnesation-Based Strategies for the Functionalization of Imidazole: 2001–2010.- L. Fu: Metalation of Oxazoles and Benzoxazoles.- S. Roy • S. Roy • G. W. Gribble: Metalation of Pyrazoles and Indazoles.- J. C. Badenock: Metalation Reactions of Isoxazoles and Benzisoxazoles.- Y.-J. Wu: Thiazoles and Benzothiazoles.- C. F. Nutaitis: Isothiazoles and Benzisothiazoles.- E. R. Biehl: Recent Advances in the Synthesis of Thiophenes and Benzothiophenes.- J. M. Lopchuk: Mesoionics.- J. M. Lopchuk: Azoles with 3-4 Heteroatoms.

N Heterocyclic Carbenes in Transition Metal Catalysis and Organocatalysis

N Heterocyclic Carbenes in Transition Metal Catalysis and Organocatalysis Book
Author : Catherine S.J. Cazin
Publisher : Springer Science & Business Media
Release : 2010-10-04
ISBN : 9789048128662
Language : En, Es, Fr & De

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Book Description :

N-Heterocyclic Carbenes in Transition Metal Catalysis and Organocatalysis features all catalytic reactions enabled by N-heterocyclic carbenes (NHCs), either directly as organocatalysts or as ligands for transition metal catalysts. An explosion in the use of NHCs has been reported in the literature during the past seven years making this comprehensive overview highly apropos. The book begins with an introductory overview of NHCs which could have been subtitled all you need to know about NHCs. The main body of the book is dedicated to applications of NHCs in catalysis. In addition to the success stories of NHCs in metathesis, NHCs in cross coupling and more recently NHCs in organocatalysis, all other less publicized areas are also covered. As the success of NHCs is generally attributed to their potential to stabilize metal centres, the inclusion of a chapter on the decomposition of NHC catalysts is pertinent. The book closes with a chapter describing the applications of NHCs in industrial processes, which is the first coverage of its kind, and brings a unique industrial context to this book. Included in this book: Historical aspects of NHCs Synthetic pathways to NHC precursors, free NHCs and complexes Methods of characterisation of NHCs and related complexes Electronic properties of NHCs Steric properties of NHCs and models for their description NHCs for metathesis and cross-coupling reactions NHCs as organocatalysts NHC Transition-Metal mediated oxidations, additions to multiple bonds, polymerisation and oligomerisation, cyclisations, direct arylations, reactions involving CO, C-F and C-H bond activation, ... Decomposition of NHC-containing catalysts Industrial applications involving NHC-containing catalysts N-Heterocyclic Carbenes in Transition Metal Catalysis and Organocatalysis provides a fresh view of NHCs since most contributors are young emerging researchers in the field of homogeneous catalysis using NHCs. This group of contributors is complemented by highly established academic researchers and an industrialist. This book is comprehensive, from the basic features of NHCs to the latest advances, hence it is suitable for both the novice and the expert.

Progress in Heterocyclic Chemistry

Progress in Heterocyclic Chemistry Book
Author : Anonim
Publisher : Newnes
Release : 2013-09-06
ISBN : 0080994091
Language : En, Es, Fr & De

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Book Description :

Progress in Heterocyclic Chemistry is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new, developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 25 are all written by leading researchers in their field, and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2012. As with previous volumes in the series, Volume 25 will enable academic and industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry in a convenient way. Recognized as the premiere review of heterocyclic chemistry Contributions from leading researchers in the field Systematic survey of the important 2012 heterocyclic chemistry literature