Skip to main content

Toxoplasma Gondii

In Order to Read Online or Download Toxoplasma Gondii Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Toxoplasma Gondii

Toxoplasma Gondii Book
Author : Louis M. Weiss,Kami Kim
Publisher : Academic Press
Release : 2013-08-10
ISBN : 0123965365
Language : En, Es, Fr & De

GET BOOK

Book Description :

This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists

Toxoplasma gondii

Toxoplasma gondii Book
Author : Uwe Gross
Publisher : Springer
Release : 2012-11-10
ISBN : 9783642510168
Language : En, Es, Fr & De

GET BOOK

Book Description :

For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field.

Toxoplasma Gondii Host Interactions A Story of Immune Attack and Parasite Counterattack

Toxoplasma Gondii Host Interactions  A Story of Immune Attack and Parasite Counterattack Book
Author : Jeroen P. J. Saeij,Eva Frickel,Kirk Jensen,Nicolas Blanchard
Publisher : Frontiers Media SA
Release : 2020-08-10
ISBN : 2889634027
Language : En, Es, Fr & De

GET BOOK

Book Description :

Toxoplasma gondii is an obligate intracellular parasite that can infect all warm-blooded animals, including an estimated ~30% of humans. It can cause severe disease in immune-suppressed individuals and in fetuses as well as blinding chorioretinitis in adults and children. Toxoplasma-innate immune system interactions determine early parasite control and activation of the adaptive immune system by the host and are therefore critical in determining host survival during the acute phase of infection. However, induction of an exaggerated inflammatory response can also lead to pathology. Only the chronic tissue cyst form of Toxoplasma is orally infectious. It is therefore critical for the parasite’s survival during the chronic phase to escape immune responses at this stage as well. Toxoplasma exists as genetically divergent strains mostly depending on geography, with the most strain diversity being found in South America. The key to Toxoplasma’s successful co-option of the host are proteins secreted from its rhoptry and dense granule secretory organelles. Rhoptry proteins (ROPs) are secreted into the host cell cytoplasm upon invasion while dense granule proteins (GRAs) are secreted once the parasite establishes itself in its parasitophorous vacuole (PV). GRAs can localize to the PV, the PV membrane, or are secreted beyond the PVM into the host cytoplasm. Many ROPs and GRAs are involved in modulating host cell signaling pathways and evasion of host immune responses and play important roles in Toxoplasma virulence. Polymorphisms in Toxoplasma’s ROPs and GRAs, likely determine how well these effectors bind to the divergent substrates in different host species, which can explain Toxoplasma strain differences in virulence in a particular host species. By studying Toxoplasma we have not only started to unravel how the parasite modulates immune responses to enhance its survival, replication, and transmission but we have also learned a lot about the immune system. Many unique mechanisms of immunity have indeed been defined using Toxoplasma and this parasite has aided our understanding of tissue-specific immune responses in the brain and intestine. This Research Topic will give a comprehensive overview of Toxoplasma-host immune response interactions. Most Toxoplasma virulence determinants to date have been established in murine systems and it is unclear how the parasite interacts with other intermediate hosts and humans. In addition, the interactions of Toxoplasma with some of the most relevant cell types during infection, including dendritic cells, neurons, intestinal epithelial cells or vascular endothelial cells, remain poorly understood.

The Role of Inflammatory Cytokines in Immune Responses to Toxoplasma Gondii

The Role of Inflammatory Cytokines in Immune Responses to Toxoplasma Gondii Book
Author : Anthony Joseph Marshall
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download The Role of Inflammatory Cytokines in Immune Responses to Toxoplasma Gondii book written by Anthony Joseph Marshall, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

A Bibliography of Toxoplasmosis and Toxoplasma Gondii

A Bibliography of Toxoplasmosis and Toxoplasma Gondii Book
Author : Don Edgar Eyles,Jacob Karl Frenkel
Publisher : Unknown
Release : 1953
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download A Bibliography of Toxoplasmosis and Toxoplasma Gondii book written by Don Edgar Eyles,Jacob Karl Frenkel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Toxoplasma Gondii

Toxoplasma Gondii Book
Author : Louis M. Weiss,Kami Kim
Publisher : Elsevier
Release : 2011-04-28
ISBN : 9780080475011
Language : En, Es, Fr & De

GET BOOK

Book Description :

Toxoplasmosis is caused by a one-celled protozoan parasite known as Toxoplasma gondii. In the United States, it is estimated that approximately 30% of cats, the primary carriers, have been infected by T. gondii. Most humans contract toxoplasmosis by eating cyst-contaminated raw or undercooked meat, vegetables, or milk products or when they come into contact with the T. gondii eggs from cat feaces while cleaning a cat's litterbox, gardening, or playing in a sandbox. Approx 1 in 4 (more than 60 million) people in the USA are infected with the parasite, and in the UK between 0.5 and 1% of individuals become infected each year. By the age of 50, 40% of people test positive for the parasite. The predilection of this parasite is for the central nervous system (CNS) causing behavioral and personality alterations as well as fatal necrotizing encephalitis, and is especially dangerous for HIV infected patients. Though there have been tremendous strides in our understanding of the biology of Toxoplasma gondii in the last decade, there has been no systemic review of all of the information that has accumulated. Toxoplasma gondii provides the first comprehensive summary of literature on this organism by leading experts in the field who were responsible for organising the 7th International Congress on Toxoplasmosis in May 2003. It offeres systematic reviews of the biology of this pathogen as well as descriptions of the methods and resources used. Within the next year the T. gondii genome will be completed making this an indispensable research resource for biologists, physicians, parasitologists, and for all those contemplating experiments using T. gondii. * Serves as a model for understanding invasion of host cells by parasites, immune response, motility, differentiation, phylogenetics, evolution and organelle acquisition * Discusses the protocols related to genetic manipulation, cell biology and animal models while also providing reference material on available resources for working with this organism

Toxoplasma gondii

Toxoplasma gondii Book
Author : Christopher J. Tonkin
Publisher : Humana
Release : 2020-11-23
ISBN : 9781493998593
Language : En, Es, Fr & De

GET BOOK

Book Description :

This volume covers a diverse collection of protocols currently being used by the Toxoplasma research community, and also looks at innovative methods that are pushing the boundaries of possibilities. Chapters in this book discuss topics such as isolation and genotyping of Toxoplasma gondii strains; assessing rhoptry secretion in T. gondii; plate-based quantification of stimulated Toxoplasma egress; methods to study ocular toxoplasmosis; and metabolic analysis of Toxoplasma gondii tachyzoites. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Toxoplasma gondii: Methods and Protocols is a valuable resource for students or groups starting off in the field, as well as laboratories interested in implementing the latest techniques described in the book.

Toxoplasma Gondii Co opts Host Immune Signaling by Secretion of a Polymorphic Tyrosine Kinase ROP16

Toxoplasma Gondii Co opts Host Immune Signaling by Secretion of a Polymorphic Tyrosine Kinase  ROP16 Book
Author : Anonim
Publisher : Stanford University
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Toxoplasma gondii is an obligate, intracellular parasite of the Apicomplexan phylum that is able to infect nearly all warm-blooded vertebrates. This capability for survival in a variety of host niches is reflected in the diversification of Toxoplasma strains. Strains differ dramatically in their interaction with hosts, and a fruitful approach towards understanding the molecular underpinnings of disease has been to identify and characterize drivers of strain-specific differences in host response. Chapter 1 provides a general introduction to Toxoplasma gondii and its ability to modulate host immunity, with special attention given to what is known about the mechanisms behind strain-specific phenotypes and the role of one particular player, ROP16. Chapter 2 describes experiments demonstrating that Toxoplasma secretes a polymorphic tyrosine kinase, ROP16, that can directly phosphorylate host STAT6. These experiments made use of a targeted disruption of the ROP16 locus in Type I parasites to identify ROP16-dependent signaling pathways, and used biochemical approaches to dissect the mechanism by which ROP16 is able to induce rapid STAT6 activation. Chapter 3 describes work demonstrating that ROP16 activation of STAT6 directs murine macrophage polarization towards an alternatively activated (M2) phenotype. In Chapter 4, the avian host response to Toxoplasma is examined to determine whether strain-specific differences in host response might be inverted in non-mammalian hosts. We show that strain-specific transcriptional host response, as well as transcriptional host response modulated by ROP16, appears very similar in chickens as in mice and humans. This suggests that variance between mammalian and avian host species in general may not be the source of selective pressure for the success of these common strains, or of ROP16's variability. Chapter 5 concludes with a discussion of future directions for further characterization of ROP16's role in modulating host response. We show that ROP16 interacts with host chromatin and suggest that investigation of ROP16's function in the host nucleus might yield further molecular insights as to how Toxoplasma is able to co-opt host cells and influence the course of infection.

Case Studies in Infectious Disease Toxoplasma Gondii

Case Studies in Infectious Disease  Toxoplasma Gondii Book
Author : Peter Lydyard,Michael Cole,John Holton,Will Irving,Nino Porakishvili,Pradhib Venkatesan,Kate Ward
Publisher : Garland Science
Release : 2009-12-01
ISBN : 1136985433
Language : En, Es, Fr & De

GET BOOK

Book Description :

Case Studies in Infectious Disease: Toxoplasma gondii presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.

Studies on the Biology of Toxoplasma Gondii Nicolle and Manceaux 1908 an Important Protozoan Parasite of Man and Many Animals

Studies on the Biology of Toxoplasma Gondii  Nicolle and Manceaux  1908   an Important Protozoan Parasite of Man and Many Animals Book
Author : Salih Mehmet Yilmaz
Publisher : Unknown
Release : 1971
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Studies on the Biology of Toxoplasma Gondii Nicolle and Manceaux 1908 an Important Protozoan Parasite of Man and Many Animals book written by Salih Mehmet Yilmaz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Toxoplasma gondii

Toxoplasma gondii Book
Author : Uwe Gross
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642510140
Language : En, Es, Fr & De

GET BOOK

Book Description :

For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field.

Toxoplasma Gondii

Toxoplasma Gondii Book
Author : Melvin B. Goodson,Don Winslow
Publisher : Nova Science Pub Incorporated
Release : 2013-01-01
ISBN : 9781626183490
Language : En, Es, Fr & De

GET BOOK

Book Description :

Toxoplasma gondii is a parasite of the phylum Apicomplexa, Coccidia order, being an obligate intracellular protozoan that affects humans and diverse vertebrate hosts. In this book, the authors discuss its prevalence in humans and animals, genetic structure and role in disease distribution. Topics include the congenital transmission of toxoplasma gondii in ovine; the role of chickens in the transmission of toxoplasmosis to humans; updates on the serological and molecular diagnosis of toxoplasmosis; epidemiology and control of toxoplasmosis in dogs, cats, bovine, and in public health.

A Bibliography of Toxoplasmosis and Toxoplasma Gondii

A Bibliography of Toxoplasmosis and Toxoplasma Gondii Book
Author : Don Edgar Eyles,Jacob Karl Frenkel
Publisher : Unknown
Release : 1952
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download A Bibliography of Toxoplasmosis and Toxoplasma Gondii book written by Don Edgar Eyles,Jacob Karl Frenkel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Toxoplasma Gondii

Toxoplasma Gondii Book
Author : Sean L. Hall
Publisher : Unknown
Release : 2021-11-29
ISBN : 9781536110678
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Toxoplasma Gondii book written by Sean L. Hall, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Prevalence of Toxoplasma Gondii

The Prevalence of Toxoplasma Gondii Book
Author : Vijay Lal,Muhammad Akram,Roshan Lal
Publisher : LAP Lambert Academic Publishing
Release : 2014-05-21
ISBN : 9783659547393
Language : En, Es, Fr & De

GET BOOK

Book Description :

Although a lot of researches have been conducted on the prevalence of Toxoplasma gondii in different localities of the world, but in this book the main discussion is, on the overall prevalences of Toxoplasma gondii in humans. There is also an emphasis on the gender and age differences in its prevalences. Treatment and prevention of T. gondii, by different therapeutic interventions, is also taken under consideration.

Studies on Early Immune Responses to Toxoplasma Gondii

Studies on Early Immune Responses to Toxoplasma Gondii Book
Author : L. Cristina Gavrilescu
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

In sum, these studies show that death during Toxoplasma infection may be the result of either excessive type 1 cytokine response, or inadequate Th1 differentiation and effector function. My work shows that this outcome depends on both parasite and host genetic background.

Toxoplasma Gondii Oocysts in Water

Toxoplasma Gondii Oocysts in Water Book
Author : Katlyn Elle Wainwright
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Toxoplasma Gondii Oocysts in Water book written by Katlyn Elle Wainwright, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

A Bibliography of Toxoplasmosis and Toxoplasma Gondii

A Bibliography of Toxoplasmosis and Toxoplasma Gondii     Book
Author : National Institutes of Health (U.S.)
Publisher : Unknown
Release : 1952
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download A Bibliography of Toxoplasmosis and Toxoplasma Gondii book written by National Institutes of Health (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.