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Toxicology

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Postmortem Toxicology

Postmortem Toxicology Book
Author : Timothy P. Rohrig
Publisher : Academic Press
Release : 2019-02-22
ISBN : 0128151641
Language : En, Es, Fr & De

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Book Description :

Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examines pre-analytical factors, storage containers/conditions, prior medical interventions and therapy, along with information from the scene investigation and anatomical findings. This reference also provides explanation of the complicating conditions for the interpretation of the toxicological results due to postmortem decomposition, embalming artifacts and the postmortem redistribution of drugs. Tolerance is also discussed as an aid to interpreting results from a habitual/chronic user of medications and/or drugs of abuse. The book is geared towards the current practitioner; however, it is written to be used as a valuable reference for a graduate or post-graduate level courses in forensic toxicology or forensic pathology. Presents a holistic approach to the interpretation of toxicology results Covers pre-analytical factors, storage containers/conditions, prior medical interventions, therapy, and much more Written for the current practitioner, but an excellent resource for graduate level students training in the field of forensic toxicology

Toxicological Risk Assessment and Multi System Health Impacts from Exposure

Toxicological Risk Assessment and Multi System Health Impacts from Exposure Book
Author : Aristidis M. Tsatsakis
Publisher : Elsevier
Release : 2021-08-01
ISBN : 0323853587
Language : En, Es, Fr & De

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Book Description :

Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. • Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field • Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease • Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research

Toxicology

Toxicology Book
Author : Hans Marquardt,Siegfried G. Schäfer,Roger O. McClellan,Frank Welsch
Publisher : Academic Press
Release : 1999-10-05
ISBN : 0080543111
Language : En, Es, Fr & De

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Book Description :

Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments. Key Features * Comprehensive text, covering all aspects of the field of toxicology * Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects * Identifies the various classes of chemical compounds responsible for the toxic effects * Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention * Adapted from a very successful German text, this edition is completely revised and expanded * The text is well illustrated with diagrams, charts, and tables

Illustrated Toxicology

Illustrated Toxicology Book
Author : PK Gupta
Publisher : Academic Press
Release : 2018-04-04
ISBN : 0128132140
Language : En, Es, Fr & De

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Book Description :

Illustrated Toxicology: With Study Questions is an essential, practical resource for self-study and guidance catering to a broad spectrum of students. This book covers a range of core toxicological areas, including pesticides, radioactive materials and poisonous plants, also presenting a section on veterinary toxicology. Across 16 chapters, the book presents key concepts with the aid of over 250 detailed, full-color illustrations. Each section is supplemented with practical exercises to support active learning. This combination of clear illustrations and sample testing will help readers gain a deeper understanding of toxicology. This book is useful for toxicology, pharmacy, medical and veterinary students, and also serves as a refresher for academics and professionals in the field, including clinical pharmacists, forensic toxicologists, environmentalists and veterinarians. Includes comprehensive coverage of key toxicological concepts for study and revision Provides a visual learning aid with over 250 full-color illustrations Enhances understanding and memory retention of core concepts with the use of practical exercises

Molecular Toxicology

Molecular Toxicology Book
Author : Nick Plant
Publisher : Taylor & Francis
Release : 2021-02-26
ISBN : 1000150216
Language : En, Es, Fr & De

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Book Description :

Molecular Toxicology is a concise introduction to the subject, taking the reader through the theoretical principles of toxicology followed by specific examples. In the first section, the concepts behind possible mechanisms of toxicity are described (e.g. the specific enzyme or receptor system) using examples where appropriate. Following this a series of examples are used to show the extension of concept into the real world, in an organ specific manner. The book concludes with a section outlining toxicity assessment methods, where the impact of molecular biology is having a considerable impact, including DNA microarrays, proteomics and bioinformatics.

Public Health Consequences of E Cigarettes

Public Health Consequences of E Cigarettes Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems
Publisher : National Academies Press
Release : 2018-05-18
ISBN : 030946837X
Language : En, Es, Fr & De

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Book Description :

Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Occupational Toxicology

Occupational Toxicology Book
Author : Chris Winder,Neill H. Stacey
Publisher : CRC Press
Release : 2004-02-11
ISBN : 1482289288
Language : En, Es, Fr & De

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Book Description :

Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment.

Assessing Ocular Toxicology in Laboratory Animals

Assessing Ocular Toxicology in Laboratory Animals Book
Author : Andrea B Weir,Margaret Collins
Publisher : Springer Science & Business Media
Release : 2012-12-04
ISBN : 1627031642
Language : En, Es, Fr & De

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Book Description :

Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.

An Introduction to Toxicology

An Introduction to Toxicology Book
Author : Philip C. Burcham
Publisher : Springer Science & Business Media
Release : 2013-11-19
ISBN : 144715553X
Language : En, Es, Fr & De

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Book Description :

This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​

Veterinary Toxicology

Veterinary Toxicology Book
Author : Ramesh C. Gupta
Publisher : Elsevier
Release : 2011-04-28
ISBN : 9780080481609
Language : En, Es, Fr & De

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Book Description :

Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Plant Toxicology

Plant Toxicology Book
Author : Bertold Hock,Erich F. Elstner
Publisher : CRC Press
Release : 2004-09-28
ISBN : 0203023889
Language : En, Es, Fr & De

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Book Description :

In order to keep track of all the compounds and pathogens affecting plant metabolism and development, you would need to spend all your waking hours combing periodicals and the Internet in dozens of languages, as new toxins via pollutants and migratory or mutant pathogens are being discovered every day. Plant Toxicology, Fourth Edition start

Hamilton and Hardy s Industrial Toxicology

Hamilton and Hardy s Industrial Toxicology Book
Author : Raymond D. Harbison,Marie M. Bourgeois,Giffe T. Johnson
Publisher : John Wiley & Sons
Release : 2015-04-13
ISBN : 0470929731
Language : En, Es, Fr & De

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Book Description :

Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals

An Introduction to Aquatic Toxicology

An Introduction to Aquatic Toxicology Book
Author : Mikko Nikinmaa
Publisher : Elsevier
Release : 2014-07-01
ISBN : 0124115810
Language : En, Es, Fr & De

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Book Description :

An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field. Provides with the latest perspectives on the impacts of toxicants on aquatic environments, such as nanotoxicology, toxicogenomics, ocean acidification and eutrophication Offers a complete overview, beginning with the origins of aquatic toxicology and concluding with potential future challenges Includes guidance on testing methods and a glossary of aquatic toxicology terms.

In Vitro Toxicology

In Vitro Toxicology Book
Author : Alok Dhawan,Seok (Soga) Kwon
Publisher : Academic Press
Release : 2017-11-13
ISBN : 0128047712
Language : En, Es, Fr & De

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Book Description :

In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. Discusses new techniques and protocols in a clear and concise manner includes examinations of nanotoxicity, genotoxicity and carcinogenicity Explains practical laboratory methods and the theories behind in vitro testing

Small Animal Toxicology E Book

Small Animal Toxicology   E Book Book
Author : Michael E. Peterson,Patricia A. Talcott
Publisher : Elsevier Health Sciences
Release : 2013-08-07
ISBN : 0323241980
Language : En, Es, Fr & De

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Book Description :

Diagnose and determine treatment for toxic exposures in small animals with this quick reference! Small Animal Toxicology, 3rd Edition covers hundreds of potentially toxic substances, providing the information you need to manage emergency treatment and prevent poisonings in companion animals. To help you identify an unknown poison, this guide provides a list of potential toxins based on clinical signs or symptoms. It also includes a NEW color insert with 85 full-color photographs of toxic plants and of lesions associated with various poisonings. Written by respected veterinarian Michael E. Peterson and board-certified veterinary toxicologist Patricia A. Talcott, along with a team of expert contributors, this edition covers a wide variety of topics including toxicodynamics, toxicokinetics, effective history taking, recognizing clinical signs of toxic exposures, managing emergencies, and supportive care of the poisoned patient. Comprehensive coverage of toxins/poisons includes the full range of substances from acetaminophen to zinc, including home products, prescription medicines, recreational drugs, and more. Guidelines to evaluation, diagnosis and treatment include examinations of the source, toxic dose, toxicokinetics, clinical signs, minimum database, confirming tests, treatment progress and differential diagnosis for each specific toxicant. Coverage of common poisonous substances includes grapes and raisins, nicotine, mercury, mushrooms, Christmas-time plants, and snake and spider venoms. Toxicological Concepts section provides information on toxicologic principles such as history taking, providing supportive care, and managing emergency treatment. General Exposures section addresses nontraditional toxicology such as indoor environmental air, pesticides, pharmaceuticals, and toxicities in pregnant and lactating animals. Miscellaneous Toxicant Groups section covers commonly encountered specific toxicants, the proper use of diagnostic laboratories, use of human poison control centers, and antidotes for specific toxins. More than 50 international contributors provide up-to-date, authoritative advice on treating poisonings and intoxications. 8 NEW chapters cover topics including legal considerations in toxicology cases, responding to mass exposures, and poisonings in birds, small mammals, and geriatric patients. NEW color insert shows 85 of the most commonly encountered toxic substances for at-a-glance identification. UPDATED Signs and Symptoms index makes it easier to find information on a toxic agent by presenting signs rather than requiring the formulation of a diagnosis. UPDATED information on agents most likely to cause a toxic reaction includes natural flea products and an expanded section on human medications. NEW quick-access format with bold headings and convenient tables and boxes allows quick retrieval of information in emergency situations.

Handbook on the Toxicology of Metals

Handbook on the Toxicology of Metals Book
Author : Gunnar F. Nordberg,Max Costa
Publisher : Academic Press
Release : 2021-12-10
ISBN : 0128231386
Language : En, Es, Fr & De

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Book Description :

Handbook on the Toxicology of Metals, Volume II: Specific Metals, Fifth Edition provides complete coverage of 38 individual metals and their compounds. This volume is the second volume of a two-volume work which emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems with a focus on human health effects Includes information on sources, transport, and the transformation of metals in the environment Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment, and prevention of 38 metallic elements and their compounds

Veterinary Toxicology for Australia and New Zealand

Veterinary Toxicology for Australia and New Zealand Book
Author : Rosalind Dalefield
Publisher : Elsevier
Release : 2017-06-23
ISBN : 0127999124
Language : En, Es, Fr & De

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Book Description :

Veterinary Toxicology for Australia and New Zealand is a reference suited to the unique challenges of veterinary practice in Australia and New Zealand. Both streamlined and thorough in its coverage of poisons and treatments for those locations, this focused approach allows readers to quickly find relevant information that is presented in a concise and logical manner that is useful to clinicians. The authors draw upon a wealth of knowledge of the particularities of toxicology in Australia and New Zealand to present readers with the up-to-date information required to efficiently and effectively diagnose and treat their patients. Highlights toxins of specific concern in Australia and New Zealand Structures information in a logical way so that it can be located quickly Offers up-to-date information on current and emerging risks

Basic Science in Toxicology

Basic Science in Toxicology Book
Author : Glyn N. Volans
Publisher : Taylor & Francis Group
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Basic Science in Toxicology book written by Glyn N. Volans, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fundamentals Of Aquatic Toxicology

Fundamentals Of Aquatic Toxicology Book
Author : Gary M. Rand
Publisher : CRC Press
Release : 1995-10-05
ISBN : 9781560320913
Language : En, Es, Fr & De

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Book Description :

This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.

Loomis s Essentials of Toxicology

Loomis s Essentials of Toxicology Book
Author : A. Wallace Hayes,Tao Wang,Darlene Dixon,Ted A. Loomis
Publisher : Academic Press
Release : 2019-10-24
ISBN : 0128159227
Language : En, Es, Fr & De

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Book Description :

Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health. Provides a revised and updated edition of one of the "gold" works in the field Includes both principles and methods Requires minimal background in chemistry and biology Expanded Information Sources in Toxicology