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Toxicological Evaluation Of Electronic Nicotine Delivery Systems

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Toxicological Evaluation of Electronic Nicotine Delivery Products

Toxicological Evaluation of Electronic Nicotine Delivery Products Book
Author : Manuel Peitsch,Julia Hoeng
Publisher : Academic Press
Release : 2021-01-14
ISBN : 0128209356
Language : En, Es, Fr & De

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Book Description :

Toxicological Evaluation of Electronic Nicotine Delivery Products (ENDP) discusses the scientific basis for the toxicological assessment and evaluation of ENDPs. The book covers aerosol chemistry, in vitro and in vivo studies as well as clinical studies. It provides the basis for the evaluation of short and long term-effects, along with relative risks. It also examines the potential role of ENDPs in tobacco harm reduction and how they may reduce the risk of disease in smokers who switch to them. This book is a comprehensive resource for toxicologists, health practitioners and public health professionals who want the scientific information necessary to assess the relative risk of ENDPs when compared with cigarette smoking and cessation. Delivers a comprehensive overview of current state of science Offers an integrated analysis of e-cigarettes and heated tobacco products Provides guidance for methodologies

Public Health Consequences of E Cigarettes

Public Health Consequences of E Cigarettes Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems
Publisher : National Academies Press
Release : 2018-05-18
ISBN : 030946837X
Language : En, Es, Fr & De

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Book Description :

Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease Book
Author : Anonim
Publisher : U.S. Government Printing Office
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Electronic Cigarettes and Vape Devices

Electronic Cigarettes and Vape Devices Book
Author : Susan Chu Walley,Karen Wilson
Publisher : Springer Nature
Release : 2021-08-12
ISBN : 3030786722
Language : En, Es, Fr & De

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Book Description :

Electronic cigarettes (E-cigarettes), also known as vape devices or by trade names such as JUUL, are handheld devices that aerosolize liquid commonly containing nicotine, humectants and flavorings. Used by 1 in 5 high school students in 2020, they are the most common tobacco product used by youth. E-cigarette use has been associated with a variety of health issues such as nicotine addiction, e-cigarette or vaping associated lung illness (EVALI), seizures, and increased risk of cardiovascular disease. This first-of-its-kind book begins with an introduction and background on the historical context of tobacco products. The next chapters provide an overview of the e-cigarette landscape and reviews the e-cigarette devices and solutions and the evolution of these products. This is followed by reviews of the health effects of e-cigarettes on users and non-users and includes recommendations for prevention and treatment of youth e-cigarette use. The last few chapters address the public health impact of e-cigarettes with a review of the evidence of e-cigarettes in smoking cessation. The book closes with policy and advocacy approaches and a resource page. E-cigarette and vape device use pose a public health crisis. This book contains succinct practical information and is a key reference for pediatricians as well as clinicians of all specialities. It also serves as a resource for health professionals, including tobacco dependence treatment providers and public health experts.

Reproductive and Developmental Toxicology

Reproductive and Developmental Toxicology Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2022-03-31
ISBN : 0323915604
Language : En, Es, Fr & De

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Book Description :

Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more

Preventing Tobacco Use Among Youth and Young Adults

Preventing Tobacco Use Among Youth and Young Adults Book
Author : United States. Public Health Service. Office of the Surgeon General
Publisher : U.S. Government Printing Office
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

NOTE: NO FURTHER DISCOUNT FOR THIS PRINT PRODUCT -- OVERSTOCK SALE -- Significantly reduced list price This Surgeon General s Report details the causes and the consequences of tobacco use among youth and young adults by focusing on the social, environmental, advertising, and marketing influences that encourage youth and young adults to initiate and sustain tobacco use. This is the first time tobacco data on young adults as a discrete population have been explored in detail. The report also highlights successful strategies to prevent young people from using tobacco. This three volume set includes the following items: A booklet containing highlights from the 2012 Surgeon General s report on tobacco use among youth and teens ages 12 through 17 and young adults ages 18 through 26. This booklet provides an overview of tobacco use within this targeted age group. The second booklet is an Executive Summary with two messages. One message from for Kathleen Sebelius, Secretary of Health and Human Services and a second message from Howard Koh, Assistant Secretary of Health and contains a brief introduction to the set and summary and conclusions for each chapter contained in the final volume. The final volume contains over 800 pages of documentation, interwoven with text and data addressing the adverse health consequences of tobacco use by children and young adults. It includes research on a variety of topics, including nicotine addiction, trends in cigarette smoking among young adults, trends in smokeless tobacco use and cigar smoking over time, genetic factors in tobacco use among youth, and mass media influence on smoking to this age group to name a few. This third volume is rich with table data research findings to support the Surgeon General s concerns with America s use and tobacco. If you would like to find similiar products, please check out our Alcoholism, Smoking, and Substance Abuse resources collection at this link: https: //bookstore.gpo.gov/catalog/health-benefits/alcoholism-smoking-substance-abuse "

The Chemical Components of Tobacco and Tobacco Smoke

The Chemical Components of Tobacco and Tobacco Smoke Book
Author : Alan Rodgman,Thomas A. Perfetti
Publisher : CRC Press
Release : 2016-04-19
ISBN : 146651552X
Language : En, Es, Fr & De

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Book Description :

Authored by two longtime researchers in tobacco science, The Chemical Components of Tobacco and Tobacco Smoke, Second Edition chronicles the progress made from late 2008 through 2011 by scientists in the field of tobacco science. The book examines the isolation and characterization of each component. It explores developments in pertinent analytical

Cellular In Vitro Testing

Cellular In Vitro Testing Book
Author : John Haycock,Arti Ahluwalia,J. Malcolm Wilkinson
Publisher : CRC Press
Release : 2014-08-27
ISBN : 9814364983
Language : En, Es, Fr & De

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Book Description :

Growing cells in 2D under static conditions has long been the gold standard of cell culture, despite this method not being representative of the complex in vivo environment. The use of animal models also has clear ethical and scientific limitations, and increasingly the 3Rs (replacement, refinement, reduction) in relation to animal models are being integrated into the modern-day scientific practice. Focusing on new 3D in vitro methods now available to researchers, this book brings together examples of leading-edge work being conducted internationally for improving in vitro cell culture methods, in particular the use of systems for enabling cell culture under laminar flow and the use of 3D scaffolds for providing cells with a structure which replicates the function of the extracellular matrix and encouraging interactions more akin to an in vivo environment.

WHO Study Group on Tobacco Product Regulation

WHO Study Group on Tobacco Product Regulation Book
Author : World Health Organization
Publisher : World Health Organization
Release : 2009
ISBN : 9241209550
Language : En, Es, Fr & De

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Book Description :

This report makes available the findings of an international group of experts that provide WHO with the latest scientific and technical advice in the area of product regulation. The third report presents the conclusions reached and recommendations made by the members of the WHO Study Group on Tobacco Product Regulation at its fifth meeting, during which it reviewed two background papers specially commissioned for the meeting and which dealt, respectively, with the following two themes: devices designed for the purpose of nicotine delivery to the respiratory system in which tobacco is not necessary for their operation and setting regulatory limits for carcinogens in smokeless tobacco. The Study Group's recommendations in relation to each theme are set out at the end of the section dealing with that theme. Its overall recommendations are summarized in section 4. The Study Group intends this new set of recommendations to be useful to WHO Member States and national policymakers and regulators in shaping tobacco control policy.

Chemical Testing Using New Approach Methodologies NAMs

Chemical Testing Using New Approach Methodologies  NAMs  Book
Author : Amy J. Clippinger,Tala Henry,Carole Hirn,Todd Stedeford,Andreas Stucki,Claire Terry
Publisher : Frontiers Media SA
Release : 2022-12-16
ISBN : 2832508596
Language : En, Es, Fr & De

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Book Description :

Download Chemical Testing Using New Approach Methodologies NAMs book written by Amy J. Clippinger,Tala Henry,Carole Hirn,Todd Stedeford,Andreas Stucki,Claire Terry, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

WHO Report on the Global Tobacco Epidemic 2013

WHO Report on the Global Tobacco Epidemic  2013 Book
Author : World Health Organization
Publisher : World Health Organization
Release : 2013
ISBN : 9241505877
Language : En, Es, Fr & De

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Book Description :

"The continued success in global tobacco control is detailed in this year’s WHO Report on the Global Tobacco Epidemic, 2013. The fourth in the series, this year’s report presents the status of the MPOWER measures, with country-specific data updated and aggregated through 2012. In addition, the report provides a special focus on legislation to ban tobacco advertising, promotion and sponsorship (TAPS) in WHO Member States and an in-depth analyses of TAPS bans were performed, allowing for a more detailed understanding of progress and future challenges in this area."--Website summary.

Case Studies in Medical Toxicology

Case Studies in Medical Toxicology Book
Author : Leslie R. Dye,Christine Murphy,Diane P. Calello,Michael D. Levine,Aaron Skolnik
Publisher : Springer
Release : 2017-12-22
ISBN : 3319564498
Language : En, Es, Fr & De

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Book Description :

The ACMT National Case Conference (NCC) is a monthly discussion of novel or interesting cases in medical toxicology. Participation is through online webinar, and the conferences are recorded to allow for review at any time. The cases in this book are taken from recordings of NCC with edits and revisions by contributors and editors to demonstrate educational points. The majority of the case information is from the original recording and represents actual patient presentations. However, some of the details have been changed and fictional information added to enhance the educational value. This volume covers a broad range of toxicological topics, and specialty guidance is offered at the end of every case to aid non-toxicologists. The dilemmas are applicable to both academic and clinical medicine. A list of relevant questions is also provided for each case. Subjects include common toxicological problems, rare presentations of common problems, common problems with controversial treatments or difficult diagnoses, and rare problems. Case Studies in Medical Toxicology from the American College of Medical Toxicology is a detailed reference text on specific toxicological issues and also serves as a practical review for those taking board exams. As a result, this volume is an important and necessary resource for medical students, residents, and fellows, as well as primary-care physicians, intensivists, and toxicologistsCase Studies in Medical Toxicology from the American College of Medical Toxicology is a detailed reference text on specific toxicological issues and also serves as a practical review for those taking board exams. As a result, this volume is an important and necessary resource for medical students, residents, and fellows, as well as primary-care physicians, intensivists, and toxicologists. All proceeds from this book will be donated to the Medical Toxicology Foundation.

E Cigarette Use Among Youth and Young Adults a Report of the Surgeon General

E Cigarette Use Among Youth and Young Adults  a Report of the Surgeon General Book
Author : Centers for Disease Control and Prevention,National Center National Center for Chronic Disease Prevention and Health Promotion,U.S. Department of Health and Human Services
Publisher : Unknown
Release : 2019-07-26
ISBN : 9781082814914
Language : En, Es, Fr & De

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Book Description :

Tobacco use among youth and young adults in any form, including e-cigarettes, is not safe. In recent years, e-cigarette use by youth and young adults has increased at an alarming rate. E-cigarettes are now the most commonly used tobacco product among youth in the United States. This timely report highlights the rapidly changing patterns of e-cigarette use among youth and young adults, assesses what we know about the health effects of using these products, and describes strategies that tobacco companies use to recruit our nation's youth and young adults to try and continue using e-cigarettes. The report also outlines interventions that can be adopted to minimize the harm these products cause to our nation's youth.E-cigarettes are tobacco products that deliver nicotine. Nicotine is a highly addictive substance, and many of today's youth who are using e-cigarettes could become tomorrow's cigarette smokers. Nicotine exposure can also harm brain development in ways that may affect the health and mental health of our kids.E-cigarette use among youth and young adults is associated with the use of other tobacco products, including conventional cigarettes. Because most tobacco use is established during adolescence, actions to prevent our nation's young people from the potential of a lifetime of nicotine addiction are critical.E-cigarette companies appear to be using many of the advertising tactics the tobacco industry used to persuade a new generation of young people to use their products. Companies are promoting their products through television and radio advertisements that use celebrities, sexual content, and claims of independence to glamorize these addictive products and make them appealing to young people.

WHO Study Group on Tobacco Product Regulation Report on the scientific basis of tobacco product regulation

WHO Study Group on Tobacco Product Regulation  Report on the scientific basis of tobacco product regulation Book
Author : Anonim
Publisher : World Health Organization
Release : 2021-05-04
ISBN : 9240022724
Language : En, Es, Fr & De

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Book Description :

This eighth report of the Study Group addresses electronic nicotine delivery system (ENDS), electronic non-nicotine delivery system (ENNDS) and heated tobacco product (HTPs); however, it does not cover all aspects of these products, because many of the papers were written to meet the request of COP8, which was to review understanding on novel and emerging tobacco products (FCTC/COP8). Continued research is necessary on these products; the Study Group will cover other products of interest (including traditional products, such as waterpipes, cigarettes and smokeless tobacco) in its next report, guided by countries’ regulatory requirements and pertinent issues in tobacco product regulation. This will ensure continued, timely technical support to all countries and address all products, recognizing that their availability depends on the jurisdiction.

Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products

Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products Book
Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Public Health Implications of Raising the Minimum Age for Purchasing Tobacco Products
Publisher : National Academies Press
Release : 2015-07-23
ISBN : 0309316278
Language : En, Es, Fr & De

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Book Description :

Tobacco use by adolescents and young adults poses serious concerns. Nearly all adults who have ever smoked daily first tried a cigarette before 26 years of age. Current cigarette use among adults is highest among persons aged 21 to 25 years. The parts of the brain most responsible for cognitive and psychosocial maturity continue to develop and change through young adulthood, and adolescent brains are uniquely vulnerable to the effects of nicotine. At the request of the U.S. Food and Drug Administration, Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products considers the likely public health impact of raising the minimum age for purchasing tobacco products. The report reviews the existing literature on tobacco use patterns, developmental biology and psychology, health effects of tobacco use, and the current landscape regarding youth access laws, including minimum age laws and their enforcement. Based on this literature, the report makes conclusions about the likely effect of raising the minimum age to 19, 21, and 25 years on tobacco use initiation. The report also quantifies the accompanying public health outcomes based on findings from two tobacco use simulation models. According to the report, raising the minimum age of legal access to tobacco products, particularly to ages 21 and 25, will lead to substantial reductions in tobacco use, improve the health of Americans across the lifespan, and save lives. Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products will be a valuable reference for federal policy makers and state and local health departments and legislators.

Analytical Methods for Elucidating Harmful Exposures Related to Vaping

Analytical Methods for Elucidating Harmful Exposures Related to Vaping Book
Author : Ben Blount,Jonathan Thornburg,David L. Ashley,Trevor Mischki,Clifford Watson
Publisher : Frontiers Media SA
Release : 2022-08-29
ISBN : 2889768651
Language : En, Es, Fr & De

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Book Description :

Download Analytical Methods for Elucidating Harmful Exposures Related to Vaping book written by Ben Blount,Jonathan Thornburg,David L. Ashley,Trevor Mischki,Clifford Watson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Peering Through the Mist

Peering Through the Mist Book
Author : Applied Research Press
Publisher : CreateSpace
Release : 2015-07-28
ISBN : 9781515263289
Language : En, Es, Fr & De

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Book Description :

Electronic cigarettes (e-cigarettes) are generally recognized as a safer alternative to combusted tobacco products, but there are conflicting claims about the degree to which these products warrant concern for the health of the vapers (e-cigarette users). This paper reviews available data on chemistry of aerosols and liquids of electronic cigarettes and compares modeled exposure of vapers with occupational safety standards. Current state of knowledge about chemistry of liquids and aerosols associated with electronic cigarettes indicates that there is no evidence that vaping produces inhalable exposures to contaminants of the aerosol that would warrant health concerns by the standards that are used to ensure safety of workplaces. However, the aerosol generated during vaping as a whole (contaminants plus declared ingredients) creates personal exposures that would justify surveillance of health among exposed persons in conjunction with investigation of means to keep any adverse health effects as low as reasonably achievable. Exposures of bystanders are likely to be orders of magnitude less, and thus pose no apparent concern.

Scientific Standards for Studies on Modified Risk Tobacco Products

Scientific Standards for Studies on Modified Risk Tobacco Products Book
Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Scientific Standards for Studies on Modified Risk Tobacco Products
Publisher : National Academies Press
Release : 2012-04-19
ISBN : 0309223989
Language : En, Es, Fr & De

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Book Description :

Smoking-related diseases kill more Americans than alcohol, illegal drugs, murder and suicide combined. The passage of the Family Smoking Prevention and Tobacco Control Act of 2009 gave the FDA authority to regulate "modified risk tobacco products" (MRTPs), tobacco products that are either designed or advertised to reduce harm or the risk of tobacco-related disease. MRTPs must submit to the FDA scientific evidence to demonstrate the product has the potential to reduce tobacco related harms as compared to conventional tobacco products. The IOM identifies minimum standards for scientific studies that an applicant would need to complete to obtain an order to market the product from the FDA.