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Toxicological Aspects Of Drug Facilitated Crimes

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Toxicological Aspects of Drug Facilitated Crimes

Toxicological Aspects of Drug Facilitated Crimes Book
Author : Pascal Kintz
Publisher : Elsevier
Release : 2014-03-22
ISBN : 0124169694
Language : En, Es, Fr & De

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Book Description :

Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology. Brings together the latest research on the toxicological analysis of drug-facilitated crimes (DFC), with real-life case studies Provides up-to-date analytical techniques for determining toxicity levels in blood, urine, and hair Covers all types of toxicants involved in DFC, including alcohol, cannabis, MDMA, and a wide variety of pharmaceuticals

Hair Analysis in Clinical and Forensic Toxicology

Hair Analysis in Clinical and Forensic Toxicology Book
Author : Pascal Kintz,Alberto Salomone,Marco Vincenti
Publisher : Academic Press
Release : 2015-06-25
ISBN : 0128017104
Language : En, Es, Fr & De

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Book Description :

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair Demonstrates toxicological techniques relating to a variety of scenarios and exposure types Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Principles of Forensic Toxicology

Principles of Forensic Toxicology Book
Author : Barry S. Levine,SARAH KERRIGAN
Publisher : Springer Nature
Release : 2020-08-13
ISBN : 3030429172
Language : En, Es, Fr & De

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Book Description :

The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.

Applied Toxicology Analytical Aspects of Forensic and Clinical Toxicology

Applied Toxicology   Analytical Aspects of Forensic and Clinical Toxicology Book
Author : Braithwaite
Publisher : Wiley-Blackwell
Release : 2015-03-20
ISBN : 9781119952329
Language : En, Es, Fr & De

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Book Description :

This book describes clinical and forensic toxicology practice with a strong emphasis on the laboratory investigation of suspected poisoning and interpretation of findings within a clinical or forensic context. Split into three parts, the book starts with an overview of practical aspects, including an introduction to clinical and forensic toxicology; clinical and laboratory aspects of the diagnosis and treatment of suspected poisoning; post-mortem toxicology - the investigation of sudden or unexpected deaths; biochemical toxicology, including adsorption, distribution, metabolism and excretion of drugs and other foreign compounds; specimen collection, preservation, storage and chain of custody; analytical toxicology - extraction and isolation of drugs and poisons; chemical immunoassay, chromatographic and mass spectrometric techniques; reference materials, standards, method validation and quality assurance; and laboratory organisation and guidelines for clinical and forensic toxicology laboratories. The second part deals with specific drugs and poisons, including: amphetamines, ecstasy (MDMA) and related compounds including mephadrone and "legal highs"; cocaine; heroin and other opiates, including morphine and codeine; methadone and other important opioids; GHB and ketamine; cannabis and cannabinoids; carbon monoxide and other toxic gases; methanol and other toxic alcohols and glycols; paracetamol and other non-opioid analgesics including salicylate; antidepressents and other important psychotropic drugs; metallic poisons, including arsenic, lead, mercury, and thallium; poisonous plants and fungi; pesticides and selected herbicides; anabolic steroids and other performance-enhancing drugs in sport; and volatile substance abuse. Each chapter will typically include: background/source/use, administration, pharmacology, pharmacokinetics, investigation, detection/analysis, toxicity and treatment, dependence, agonists, bibliography/references, and case studies. Finally, the book concludes with selected special topics, including: clinical and forensic aspects of the measurement of alcohol in body fluids and the investigation of alcohol-related deaths; drug facilitated crimes - DFSA and its investigation; investigation of suspected poisoning in vulnerable groups (children and the elderly); workplace and insurance testing for drug and alcohol misuse; clinical applications of drugs of abuse screening in the treatment of drug and alcohol misuse; and drugs and driving impairment.

Detection of Drug Misuse

Detection of Drug Misuse Book
Author : Kim Wolff
Publisher : Royal Society of Chemistry
Release : 2017-07-05
ISBN : 1788012313
Language : En, Es, Fr & De

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Book Description :

Drug misuse and dependence is an ever evolving field of study, which has exploded over recent years owing to the advent of the internet. Due to the ever-growing number of young people using drugs recreationally and the privatisation of drug screening and detection services, there is the need to disseminate evidence-based information concerning the technology and methods available for studying this expanding field. Detection of Drug Misuse describes the current state-of-the-art techniques used for identifying and confirming drug misuse as well as recent advances in biomarkers, instrumentation and analysis methodology. The title discusses both recreational and designer drugs, including non-addictive and addictive drugs. This book is a useful and fascinating resource for healthcare professionals working in the field of drug misuse as well as academics and postgraduates researching within analytical, chromatography, medicinal and pharmaceutical chemistry; drug metabolism; addiction science; and forensic toxicology, science and medicine.

Liquid Chromatography

Liquid Chromatography Book
Author : Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola
Publisher : Elsevier
Release : 2017-06-23
ISBN : 0128093447
Language : En, Es, Fr & De

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Book Description :

Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Taphonomy of Human Remains

Taphonomy of Human Remains Book
Author : Eline M. J. Schotsmans,Nicholas Márquez-Grant,Shari L. Forbes
Publisher : John Wiley & Sons
Release : 2017-01-23
ISBN : 1118953339
Language : En, Es, Fr & De

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Book Description :

A truly interdisciplinary approach to this core subject within Forensic Science Combines essential theory with practical crime scene work Includes case studies Applicable to all time periods so has relevance for conventional archaeology, prehistory and anthropology Combines points of view from both established practitioners and young researchers to ensure relevance

Phytomedicine

Phytomedicine Book
Author : Rouf Ahmad Bhat,Khalid Rehman Hakeem,Moonisa Aslam Dervash
Publisher : Academic Press
Release : 2021-03-01
ISBN : 0128241101
Language : En, Es, Fr & De

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Book Description :

Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion. Discusses phytotherapeutic properties for a wide range of medical conditions, including anti-pyretic, anti-infective, anti-malarial, Anti-AIDS, anti-diabetic, anti-cancerous, immune-modulatory applications Includes a discussion of synergistic effects of formulations and antagonistic drug interactions Addresses advancements and achievements of novel plant-based drugs using molecular, enzymatic activities and various technological tools in an eco-friendly fashion

Deviant Leisure

Deviant Leisure Book
Author : Thomas Raymen,Oliver Smith
Publisher : Springer Nature
Release : 2019-09-28
ISBN : 303017736X
Language : En, Es, Fr & De

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Book Description :

This book brings together a collection of critical essays that challenge the existing dogma of leisure as an unmitigated social good, in order to examine the commodification and marketisation of leisure across a number of key sites. Leisure and consumer culture have become symbolic of the individual freedoms of liberal society, ostensibly presenting individuals with the opportunity to display individual creativity, cultural competence and taste. This book problematizes these assertions, and considers the range of harms that emerge in a consumer society predicated upon intense individualism and symbolic competition. Approaching the field of commodified leisure through the lens of social harm, this collection of essays pushes far beyond criminology’s traditional interest in ‘deviant’ forms of leisure, to consider the normalized social, interpersonal and environmental harms that emerge at the intersection of leisure and consumer capitalism. Capturing the current vitality and interdisciplinary scope of recent work which is underpinned by the deviant leisure perspective, this collection uses case studies, original research and other forms of empirical enquiry to scrutinise activities that range from alcohol consumption and gambling, to charity tourism; CrossFit training; and cosmetic pharmaceuticals. Drawn from researchers across the UK, US, Europe and Australia, Deviant Leisure: Criminological Perspectives on Leisure and Harm represents the first systematic attempt at a criminological consideration of the global harms of the leisure industry; firmly establishing leisure as a subject of serious criminological importance.

Light in Forensic Science

Light in Forensic Science Book
Author : Mire Zloh,Jacqueline L Stair,Giorgia Miolo
Publisher : Royal Society of Chemistry
Release : 2018-04-18
ISBN : 1782627685
Language : En, Es, Fr & De

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Book Description :

The identification and quantification of material present and collected at a crime scene are critical requirements in investigative analyses. Forensic analysts use a variety of tools and techniques to achieve this, many of which use light. Light is not always the forensic analyst’s friend however, as light can degrade samples and alter results. This book details the analysis of a range of molecular systems by light-based techniques relevant to forensic science, as well as the negative effects of light in the degradation of forensic evidence, such as the breakage of DNA linkages during DNA profiling. The introductory chapters explain how chemiluminescence and fluorescence can be used to visualise samples and the advantages and limitations of available technologies. They also discuss the limitations of our knowledge about how light could alter the physical nature of materials, for example by breaking DNA linkages during DNA profiling or by modifying molecular structures of polymers and illicit drugs. The book then explains how to detect, analyse and interpret evidence from materials such as illicit drugs, agents of bioterrorism, and textiles, using light-based techniques from microscopy to surface enhanced Raman spectroscopy. Edited by active photobiological and forensic scientists, this book will be of interest to students and researchers in the fields of photochemistry, photobiology, toxicology and forensic science.

MPTET Varg 3 20 Full length Mock Tests Subject wise English Envirnoment Tests Practice Kit

MPTET Varg 3   20 Full length Mock Tests   Subject wise  English   Envirnoment  Tests   Practice Kit Book
Author : Rohit Manglik
Publisher : EduGorilla
Release : 2020-05-20
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Madhya Pradesh Teacher Eligibility Test (MPTET) is a state-level exam conducted by the Madhya Pradesh Professional Examination Board (MPPEB). MPPEB is the largest examination conducting body of Madhya Pradesh which conducts various exams for professional courses and streams. MPTET Paper I (VARG 3) is specifically conducted to assess the eligibility of the candidates for the post of Primary Teachers in the Government schools of Madhya Pradesh. MPTET Paper I (VARG 3) is one of the most distinguished exams in the teaching sector and provides candidates with a lot of career perspectives.

Forensic Toxicology

Forensic Toxicology Book
Author : Max M. Houck
Publisher : Academic Press
Release : 2018-01-02
ISBN : 0128008180
Language : En, Es, Fr & De

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Book Description :

Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

Forensic DNA Applications

Forensic DNA Applications Book
Author : Dragan Primorac,Moses Schanfield
Publisher : CRC Press
Release : 2014-01-29
ISBN : 1466580232
Language : En, Es, Fr & De

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Book Description :

Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions a

P5 Medicine and Justice

P5 Medicine and Justice Book
Author : Santo Davide Ferrara
Publisher : Springer
Release : 2018-03-27
ISBN : 3319670921
Language : En, Es, Fr & De

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Book Description :

This book describes the state of the art and future prospects of the most important bio-medicolegal subdisciplines in the post-genomic framework of personalized medicine. Focusing on the three main themes Innovation, Unitariness and Evidence, the book addresses a wide range of topics, including: Bio-Medicolegal and Criminological Sciences, Forensic Pathology and Anthropology, Clinical and Forensic Medicine in Living Persons (from Interpersonal Violence to Personal Injury and Damage, Malpractice, Personal Identification and Age Estimation), Forensic Genetics and Genomics, and Toxicology and Imaging. The unitariness of the “Bio-Medicolegal Sciences”, historically founded on the accuracy and rigor of the methods of ascertainment and criteria of evaluation, should be re-established on the basis of molecular evidence, and used to promote Personalized Justice. Taken together, the book’s conclusions and future perspectives outline a vision of transdisciplinary innovation and future evidence in the framework of personalized justice.

Toxicology Cases for the Clinical and Forensic Laboratory

Toxicology Cases for the Clinical and Forensic Laboratory Book
Author : Hema Ketha,Uttam Garg
Publisher : Academic Press
Release : 2020-06-20
ISBN : 0128163739
Language : En, Es, Fr & De

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Book Description :

Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format Presents unique and challenging cases in clinical laboratories contributed by experts in the field Consolidated format that make concepts in toxicology easy to learn and teach Key learning points highlighted with multiple choice questions

Hair in Toxicology

Hair in Toxicology Book
Author : Desmond John Tobin
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 184755251X
Language : En, Es, Fr & De

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Book Description :

Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations. This authoritative book combines contributions from experts in academic, governmental and industrial environments, to provide a unique, comprehensive look at: - Why hair can serve as an invaluable bio-resource in toxicology, with up-to-date reviews on hair growth, hair fibre formation and hair pigmentation - Information (including regulatory details) on the exposure of hair (and by extension the body) to drug and non-drug chemicals and pollutants - Toxicological issues relevant to the use of hair products (including colourants, shampoos and depilatories) - The ability of hair to capture information on personal identity, chemical exposure, and environmental interactions - How hair can provide an understanding of human life from archaeological and historical perspectives - Future direction in the use of hair in toxicology Hair in Toxicology: An Important Biomonitor is ideal as a reference and guide to investigations in the biomedical, biochemical and pharmaceutical sciences at the graduate and post graduate level.

Molecular Clinical and Environmental Toxicology

Molecular  Clinical and Environmental Toxicology Book
Author : Andreas Luch
Publisher : Springer Science & Business Media
Release : 2010-03-01
ISBN : 3764383380
Language : En, Es, Fr & De

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Book Description :

Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Neuropathology of Drug Addictions and Substance Misuse Volume 2

Neuropathology of Drug Addictions and Substance Misuse Volume 2 Book
Author : Victor R. Preedy
Publisher : Academic Press
Release : 2016-03-25
ISBN : 0128003758
Language : En, Es, Fr & De

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Book Description :

Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader’s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions Fills an existing gap in the literature by serving as a “one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body

Forensic Toxicological Aspects of Tramadol

Forensic Toxicological Aspects of Tramadol Book
Author : Pernilla Haage
Publisher : Linköping University Electronic Press
Release : 2018-11-09
ISBN : 9176851966
Language : En, Es, Fr & De

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Book Description :

One of the most difficult parts in forensic toxicology is to interpret obtained drug concentrations. Was it therapeutic, toxic or even lethal to the particular individual that the blood sample was drawn from? Concentrations of opioid drugs are especially difficult to interpret, because of large interindividual differences in innate and acquired tolerance. Tramadol is a complex drug. Not only is it an opioid, it is also a racemic drug with the (+)- and (-)-enantiomers of the parent compound and metabolites showing different pharmacological effects. Further, it is metabolized by polymorphic enzymes, which may affect the amounts of metabolites formed and possibly the enantiomer ratios of the parent compound and its metabolites. It has been speculated that particularly the (+)/(-)-enantiomer ratio of O-desmethyltramadol is related to the risk of adverse effects, and it has been shown that the ratio is affected by CYP2D6 genotype. The overall aim of the thesis was to evaluate if forensic interpretations of tramadol, regarding toxicity and time since drug administration, may be improved by the use of genotyping and enantioselective concentration determination of tramadol and its three main metabolites. To simultaneously quantify the enantiomer concentrations of tramadol, Odesmethyltramadol, N-desmethyltramadol and N,O-didesmethyltramadol in whole blood, a liquid chromatography tandem mass spectrometry (LCMS/MS) method was developed and validated. Genetic variation in CYP2D6, CYP2B6, CYP3A4 (encoding the tramadol metabolizing enzymes), ABCB1 (encoding a transport protein) and OPRM1 (encoding the ?-opioid receptor) was investigated, using pyrosequencing, xTAG, and TaqMan analysis. The methods were applied to the blood samples of two study populations; 19 healthy volunteers administered a therapeutic, single tramadol dose, and 159 tramadol positive autopsy cases. The most important finding was the positive correlations between all four enantiomer ratios and time since tramadol administration in the healthy volunteers. All enantiomer ratios except the one of tramadol was also affected by the CYP2D6 genotype, which was apparent among the autopsy cases as well. Genetic variation in CYP2D6 and possibly CYP2B6 was shown to have an impact on tramadol pharmacokinetics, although no association to neither drug related symptoms nor tramadol related causes of death was found. Tramadol intoxications were predominantly characterized by low age (median 26 years) and male sex, often with a history of substance abuse and with other drugs (at fairly low concentrations) detected in blood. In conclusion, enantiomer concentration determination combined with genotyping seems promising regarding estimations of time since drug administration, although is of low value concerning interpretations of toxicity in autopsy cases.

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology Book
Author : Robert J. Flanagan,Eva Cuypers,Hans H. Maurer,Robin Whelpton
Publisher : John Wiley & Sons
Release : 2020-08-03
ISBN : 1119122341
Language : En, Es, Fr & De

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Book Description :

Fundamentals of Analytical Toxicology is an integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. This new edition contains thoroughly revised content that reflects contemporary practices and advances in analytical methods. Expanding the scope of the 1995 World Health Organization (WHO) basic analytical toxicology manual, the text includes coverage of separation science, essential pharmacokinetics, xenobiotic absorption, distribution and metabolism, clinical toxicological and substance misuse testing, therapeutic drug monitoring, trace elements and toxic metals analysis, and importantly the clinical interpretation of analytical results. Written by a prominent team of experienced practitioners, this volume: Focuses on analytical, statistical, and pharmacokinetic principles Describes basic methodology, including colour tests and immunoassay and enzyme-based assays Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS) Fundamentals of Analytical Toxicology: Clinical and Forensic, 2nd Edition is an indispensable resource for advanced students and trainee analytical toxicologists across disciplines, such as clinical science, analytical chemistry, forensic science, pathology, applied biology, food safety, and pharmaceutical and pesticide development.