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Thermoregulation From Basic Neuroscience To Clinical Neurology

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Thermoregulation Part II

Thermoregulation Part II Book
Author : Anonim
Publisher : Elsevier
Release : 2018-11-17
ISBN : 0444640754
Language : En, Es, Fr & De

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Book Description :

Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Thermoregulation Part I

Thermoregulation Part I Book
Author : Anonim
Publisher : Elsevier
Release : 2018-11-16
ISBN : 0444639136
Language : En, Es, Fr & De

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Book Description :

Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Clinical Neurophysiology Diseases and Disorders

Clinical Neurophysiology  Diseases and Disorders Book
Author : Anonim
Publisher : Elsevier
Release : 2019-07-13
ISBN : 0444641432
Language : En, Es, Fr & De

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Book Description :

Clinical Neurophysiology: Diseases and Disorders, the latest release in the Handbook of Clinical Neurology series, reviews the current practice of clinical neurophysiology in the laboratory, by the bedside, and in the operating room or intensive care unit. The volume is organized into sections focused on diseases of the central and peripheral nervous systems, sleep disorders, and autonomic disorders. Among the CNS topics covered are epilepsy, altered states of consciousness, disorders of cognition, brain death, demyelinating diseases, stroke, pain, movement disorders, vestibular disease, and auditory disorders. Peripheral nervous system topics include focal mononeuropathies, generalized polyneuropathies, muscle diseases, hyperexcitability states, neuromuscular junction disorders, anterior horn cells diseases, and cranial neuropathies. There are also chapters on sleep apneas, hypersomnias, parasomnias, and circadian rhythm disorders. Autonomic topics include primary autonomic failure, multisystem atrophy, and postural orthostatic tachycardia syndrome. Provides an up-to-date review on the practice of the neurophysiological techniques used in the assessment of neurological diseases Explores the electrophysiological techniques used to better understand neurological function and dysfunction of the central and peripheral nervous systems Discusses monitoring neurologic function in the intensive care unit and the assessment of suspected brain death Includes discussions of various newer techniques, including functional brain mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

Clinical Neurophysiology Basis and Technical Aspects

Clinical Neurophysiology  Basis and Technical Aspects Book
Author : Anonim
Publisher : Elsevier
Release : 2019-07-03
ISBN : 0444640339
Language : En, Es, Fr & De

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Book Description :

Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology. Provides an up-to-date review on the practice of neurophysiological techniques in the assessment of neurological disease Explores the electrophysiological techniques used to better understand neurological function and dysfunction, first in the area of consciousness and epilepsy, then in the areas of the peripheral nervous system and sleep Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

Neurocognitive Development Normative Development

Neurocognitive Development  Normative Development Book
Author : Anonim
Publisher : Elsevier
Release : 2019-09-22
ISBN : 0444641513
Language : En, Es, Fr & De

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Book Description :

This is one of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The normative volume focuses on neurology, biology, genetics, and psychology of normative cognitive development. It covers the development of intellectual abilities, visual perception, motor function, language, memory, attention, executive function, social cognition, learning abilities, and affect and behavior. The book identifies when and how these functions develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.) Summarizes research on normative neurocognitive development Includes intellectual abilities, language, memory, attention, motor function, and more Discusses genetics and environmental influences on development Provides interdisciplinary information of use to both researchers and clinicians

Neurocognitive Development Disorders and Disabilities

Neurocognitive Development  Disorders and Disabilities Book
Author : Anonim
Publisher : Elsevier
Release : 2020-09-25
ISBN : 0444641491
Language : En, Es, Fr & De

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Book Description :

This is one volume of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The disorders and disabilities volume focuses on disorders of intellectual abilities, language, learning memory as well as psychiatric developmental disorders. The developmental aspects of neurological diseases in children is also covered. Chapters discuss when and how these disorders develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. Assessment, treatment, and long-term outcome are provided as well as advances in methods and tools for assessment. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.) Summarizes research on neurocognitive developmental disorders and disabilities Includes disorders of intellectual abilities, language, learning, memory, and more Separately covers developmental aspects of neurological diseases in children Features advances in methods and tools of assessment Reviews patient care, rehabilitation, and long-term outcomes Provides interdisciplinary information of use to both researchers and clinicians

Neonatal Neurology

Neonatal Neurology Book
Author : Anonim
Publisher : Elsevier
Release : 2019-07-17
ISBN : 0444640304
Language : En, Es, Fr & De

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Book Description :

Neonatal Neurology, Volume 162 in the Handbook of Clinical Neurology, series updates the reader on the latest advances in the study of neurological diseases diagnosed in the fetal and neonatal periods. With recent advances in magnetic resonance imaging, digital electroencephalography recording, and genetic testing and diagnosis, there is expanding awareness relating to early onset neurological conditions and how their early diagnosis can improve prediction of outcome and subsequent neurodevelopmental outcome. This new volume covers diagnosis and management of congenital conditions, including brain malformations, neuromuscular conditions and genetic epilepsies, as well as acquired injury related to peri-partum events, prematurity, critical illness and systemic diseases. Provides an in-depth understanding of the basic scientific research, translational research and clinical consensus across neonatal and fetal medicine Explores how early neurological diagnosis can improve prediction of outcome and how management can improve subsequent neurodevelopmental outcome Features chapters co-authored by two experts, combining expertise in both neonatal and fetal neurology

Sports Neurology

Sports Neurology Book
Author : Anonim
Publisher : Elsevier
Release : 2018-11-24
ISBN : 0444639551
Language : En, Es, Fr & De

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Book Description :

Sports Neurology is designed to be a comprehensive overview of neurology within the context of sports medicine. This definitive text addresses the history of sports neurology, including its unique role within sports medicine, and provides a detailed assessment of central and peripheral nervous system injuries and illnesses in athletes. Sports Neurology is a critical companion for all sports medicine clinicians and for neurologists who manage athletes. Provides an introduction and overview of concussion in sport, discussing the epidemiology, biomechanics and pathophysiology of concussion, as well as considerations for sideline evaluation and emergency room diagnosis and management Explores the long-term consequences of concussion and repetitive head impacts and the relationship with neurodegeneration Offers an overview of mild, moderate and severe brain injury classification; compares moderate and severe traumatic brain injury within the context of civilian, military and sports circumstances Describes key issues for the evaluation and treatment of cervical spinal cord injuries, peripheral nerve injuries, and sports-related pain Provides an overview of neuroepidemiology and the importance of obtaining meaningful sport-related neuroepidemiologic data that will ultimately provide the foundation for making data-driven decisions for central and peripheral nervous system injuries in sport

Psychopharmacology of Neurologic Disease

Psychopharmacology of Neurologic Disease Book
Author : Anonim
Publisher : Elsevier
Release : 2019-11-12
ISBN : 0444640134
Language : En, Es, Fr & De

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Book Description :

Psychopharmacology of Neurologic Disease, Volume 165 in the Handbook of Clinical Neurology series, provides clinicians with an up-to-date, critical review of the best approaches to treatment of neurologic disease as discussed by experienced clinical investigators. The book is organized into sections on dementia, delirium, movement disorders, hereditary degenerative disease, epilepsy and psychogenic seizures, brain vascular disease, pseudobulbar affect, traumatic brain injury, neuro-oncology, multiple sclerosis and other demyelinating disorders, chronic fatigue syndrome/fibromyalgia, pain, headache, sleep disorders, autoimmune encephalitis/anti- NMDA encephalitis, functional sensory neurologic symptom disorders and neurodevelopmental disorders. Each of these diagnostic categories has a significant incidence of behavioral symptomatology that is secondary to the neurologic diagnosis that can serve to complicate other therapeutic interventions, alter the course of illness, and cause distress in patients and family caregivers. Provides a systematic, evidence-based compendium of best practices in the treatment of behavioral symptomatology relating to neurologic conditions Integrates state-of-the-art approaches in treating all behavioral symptomatology across all major neurologic disorders Explores psychopharmacological intervention, non-pharmacological strategies, behavioral symptomatology, and therapeutic interventions

Sex Differences in Neurology and Psychiatry

Sex Differences in Neurology and Psychiatry Book
Author : Anonim
Publisher : Elsevier
Release : 2020-09-30
ISBN : 0444641246
Language : En, Es, Fr & De

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Book Description :

Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Neurology and Pregnancy

Neurology and Pregnancy Book
Author : Eric A.P. Steegers,Marilyn J. Cipolla,Eliza C. Miller
Publisher : Elsevier
Release : 2020-08-05
ISBN : 0444642927
Language : En, Es, Fr & De

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Book Description :

Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases. Encompasses both chronic and acute neurological disorders in pregnancy Includes epilepsy, sleep disorders, MS, headaches, neuromuscular disorders Covers spinal injury and movement disorders Contains cerebrovascular diseases and brain tumors Examines stroke, hemorrhage, TBI, preeclampsia and more Supplies illustrative case study examples

Neurology and Pregnancy

Neurology and Pregnancy Book
Author : Anonim
Publisher : Elsevier
Release : 2020-07-29
ISBN : 0444642919
Language : En, Es, Fr & De

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Book Description :

Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases. Discusses neuroendocrine, brain, PNS, and cerebro-vascular changes in pregnancy Includes neurological care of the pregnant patient Covers neuroimaging and monitoring techniques Reviews common neurological complications with pregnancy Supplies illustrative case study examples

Geriatric Neurology

Geriatric Neurology Book
Author : Anonim
Publisher : Elsevier
Release : 2019-12-18
ISBN : 0128051418
Language : En, Es, Fr & De

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Book Description :

Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings of age-related changes and the clinical information necessary to aid in diagnostics and treatment, the book serves as a useful volume for students, basic and translational scientists, and practicing clinicians on how to understand and treat common neurological disorders in the elderly. Reviews the foundations of geriatric neurology, including the fundamentals of age associated changes in molecular biology, altered pharmacokinetics and psychopharmacology that make drug therapy in the elderly different from younger patients Contains major advances in our understanding of neurodegenerative diseases Features contributions from world leaders in geriatric neurology–the broadest, most expert coverage available

Neurology of Vision and Visual Disorders

Neurology of Vision and Visual Disorders Book
Author : Anonim
Publisher : Elsevier
Release : 2021-04-06
ISBN : 0128213787
Language : En, Es, Fr & De

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Book Description :

Neurology of Vision and Visual Disorders, Volume 178 in the Handbooks of Neurology series provides comprehensive summaries of recent research on the brain and nervous system. This volume reviews alterations in vision that stem from the retina to the cortex. Coverage includes content on vision and driving derived from the large amount of time devoted in clinics to determining who is safe to drive, along with research on the interplay between visual loss, attention and strategic compensations that may determine driving suitability. The title concludes with vision therapies and the evidence behind these approaches. Each chapter is co-written by a basic scientist collaborating with a clinician to provide a solid underpinning of the mechanisms behind the clinical syndromes. Reviews the neurological underpinnings of visual perception disorders Encompasses the cortex to the retina Covers functional organization, electrophysiology and subcortical visual pathways Discusses assessment, diagnosis and management of visual perception disorders Includes international experts from Australia, Canada, Denmark, Germany, Singapore, and the UK and US

Cingulate Cortex

Cingulate Cortex Book
Author : Anonim
Publisher : Elsevier
Release : 2019-11-13
ISBN : 0444641971
Language : En, Es, Fr & De

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Book Description :

Cingulate Cortex, Volume 166 summarizes research on the cingulate cortex, including its structure and function in health and how it is compromised in disease or trauma. Chapters discuss the cingulate organization by region and area, cover its function in consciousness, attention, social cognition and spatial orientation, review neurological disorders with cingulate involvement, including neurodegenerative disorders, movement disorders, Parkinson’s, ADHD, Cognitive impairment, Palsy, Tourette’s Syndrome, chronic pain, seizures, and more. Final sections discuss the relationship between the cingulate cortex, stress and psychiatric disorders. Coverage here includes PTSD, anxiety, depression, and evidence-based treatment for same. Identifies the structure and function of all areas and regions of the cingulate cortex Discusses its role in sensory-motor, cognitive and emotional processing Covers cingulate-mediated neurological and psychiatric disorders Supplies evidence-based treatment for cingulate mediated disorders

Disorders of Emotion in Neurologic Disease

Disorders of Emotion in Neurologic Disease Book
Author : Anonim
Publisher : Elsevier
Release : 2021-08-11
ISBN : 0128222891
Language : En, Es, Fr & De

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Book Description :

Disorders of Emotion in Neurologic Disease, Volume 183 in the Handbook of Clinical Neurology Series, informs clinicians on which neurologic diseases are likely to have a secondary effect on emotion, what to look for in diagnosis, and best practices for treatment. The book begins with an understanding of the neurological basis for emotions in order to better understand what goes awry in neurological disease. It then discusses specific neurologic diseases and disorders affecting emotion. Reviews the neurology of emotions Specifies neurologic diseases that affect emotional expression Informs clinicians on how to diagnose, along with best practices for treatment Includes coverage of stroke, dementia, epilepsy, Huntington's, Parkinson's, TBI, and more

Heart and Neurologic Disease

Heart and Neurologic Disease Book
Author : Anonim
Publisher : Elsevier
Release : 2021-02-23
ISBN : 0128203897
Language : En, Es, Fr & De

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Book Description :

The Handbook of Clinical Neurology series volumes provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. Cardiac disorders and diseases may often co-occur with, or cause, subsequent neurological disorders. Heart and Neurologic Disease identifies the top cardiac diseases and disorders most likely to have neurological disorders, how they will present, and how they are best treated. It identifies the mechanisms of action explaining why the conditions co-occur, and what clinicians should look for symptom wise, and how risk may be assessed. Coverage includes genetic cardiac disorders, cardiac trauma, surgery, infection, disease, and arrhythmia. Identifies the top cardiac diseases and disorders most likely to have neurological complications Specifies how the neurological complication will present and advance and how it should be treated Discusses the mechanism of action—why the two conditions co-occur Includes genetic conditions, trauma, surgery, infection, disease, arrythmias, and more Covers prevention and risk assessment

The Frontal Lobes

The Frontal Lobes Book
Author : Anonim
Publisher : Academic Press
Release : 2019-10-05
ISBN : 0128043261
Language : En, Es, Fr & De

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Book Description :

The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more. Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders. Provides an overview of the structure, function, disorder and rehabilitation of the frontal lobes Addresses a wide variety of methodologies – from genetics and molecular biology, to optogenetics and hi-res fMRI, and more Contains content of interest to advanced students, junior researchers and clinicians getting involved in research Features the input of leaders in neuroanatomical research from around the globe – the broadest, most expert coverage available

The Human Hypothalamus

The Human Hypothalamus Book
Author : Dick F. Swaab,Ruud M. Buijs,Felix Kreier,Paul J. Lucassen,Ahmad Salehi
Publisher : Elsevier
Release : 2021-07-07
ISBN : 0128199741
Language : En, Es, Fr & De

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Book Description :

The Human Hypothalamus: Neuropsychiatric Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer’s, Parkinson’s, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more. Summarizes research on how the hypothalamus relates to neurological disorders Contains neuropsychiatric, neurodegenerative, periodic and autonomic disorders Includes the neurobiology of, and treatment for, each disorder Covers depression, anxiety, OCD, PTSD, schizophrenia, autism, aggression, addiction, and more Provides coverage of sleep and pain

Interventional Neuroradiology

Interventional Neuroradiology Book
Author : Anonim
Publisher : Elsevier
Release : 2021-01-22
ISBN : 0444640355
Language : En, Es, Fr & De

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Book Description :

Interventional Neuroradiology, Volume 179, provides a basic outline of the field of interventional neuroradiology that is accessible to fellows, residents, clinicians and researchers in various disciplines, from diagnostic and interventional radiology to vascular neurology, general and vascular neurosurgery, and vascular biology. This volume offers a timely update to experienced clinical practitioners in a logical, easy-to-follow format. Content includes neurovascular anatomy, vascular biology, neurovascular physiology, vascular imaging, as well as sections on the diagnosis and therapeutic treatment of neurovascular disease. Explores the general scope of current clinical interventional neuroradiology, both for endovascular and percutaneous image-guided diagnosis and interventions in a variety of pathologies Defines basic physiological principles (e.g., cerebral perfusion pressure, intracranial pressure, vasospasm, tissue osmolality) with reference to those most essential to the management of neurovascular diseases Discusses pathophysiology and the unique challenges of pediatric cerebrovascular diseases, as well as endovascular and surgical therapies