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The Zebrafish In Biomedical Research

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The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research Book
Author : Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders
Publisher : Academic Press
Release : 2019-11-22
ISBN : 0128124326
Language : En, Es, Fr & De

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Book Description :

The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Zebrafish in Biomedical Research

Zebrafish in Biomedical Research Book
Author : Yusuf Bozkurt
Publisher : Unknown
Release : 2020-03
ISBN : 9781789859850
Language : En, Es, Fr & De

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Book Description :

Download Zebrafish in Biomedical Research book written by Yusuf Bozkurt, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Zebrafish Model for Biomedical Research

Zebrafish Model for Biomedical Research Book
Author : Prasan R Bhandari,Kala Kumar Bharani,Amit Khurana
Publisher : Springer
Release : 2022-04-04
ISBN : 9789811652165
Language : En, Es, Fr & De

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Book Description :

This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.

Laboratory Fish in Biomedical Research

Laboratory Fish in Biomedical Research Book
Author : Livia d'Angelo,Paolo de Girolamo
Publisher : Academic Press
Release : 2021-08-28
ISBN : 0128212454
Language : En, Es, Fr & De

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Book Description :

Fish, and particularly zebrafish, have become the fastest-growing segment of the research population. They offer several advantages, in terms of biology and technologies to apply, and thus are employed in numerous research fields. Laboratory Fish in Biomedical Research: Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Swordtail Fish, Cavefish, Stickleback, Goldfish and Danionella Translucida addresses the relevant and increasing need to collect cutting-edge knowledge on husbandry, maintenance, welfare and experimental protocols of the most common freshwater species under standard laboratory conditions. Provides husbandry and management protocols, devices and water systems Shows strength and weakness of breeding Explores potential scientific applications and experimental protocols. with regards to the most used freshwater fish used for scientific purposes

Embryonic and Larval Zebrafish Bioassays for Biomedical Research

Embryonic and Larval Zebrafish Bioassays for Biomedical Research Book
Author : Joseph A. Fisher
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Laboratories around the world are using the zebrafish model for biomedical research and conducting investigations using morphological, physiological, behavioral, and genomic endpoints. All assays provide information, but physiological and behavioral endpoints or phenotypes are a fast way to understand how an animal is responding to its environment. We investigate the zebrafish model and its relevant assays with particular focus on the photomotor response screening assays. Behavioral time series data is often non-Gaussian distributed and presents a challenge for valid statistical analysis. As such, we have developed both single measure (SM) and repeated measure (RM) nonparametric permutation methods, and compared them to traditional parametric and nonparametric methods. Our proposed methods are sensible for both the zebrafish embryonic photomotor response (EPR) and larval photomotor response (LPR) locomotor screening assays, and they integrate with other zebrafish assays. The SM permutation test does notpreserve the time series aspect of the data, while the RM permutation test does. Both tests provide robust methods for the analysis of in vivo chemical hazard identification in a high throughput research environment.

Essentials of Laboratory Animal Science Principles and Practices

Essentials of Laboratory Animal Science  Principles and Practices Book
Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
Publisher : Springer Nature
Release : 2021-07-23
ISBN : 981160987X
Language : En, Es, Fr & De

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Book Description :

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research Book
Author : P. Michael Conn
Publisher : Springer Science & Business Media
Release : 2008
ISBN : 1588299333
Language : En, Es, Fr & De

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Book Description :

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Animal centric Care and Management

Animal centric Care and Management Book
Author : Dorte Bratbo Sørensen,Sylvie Cloutier,Brianna N. Gaskill
Publisher : CRC Press
Release : 2020-10-14
ISBN : 0429602057
Language : En, Es, Fr & De

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Book Description :

The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch’s definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.

Animal Welfare Assessment Volume II

Animal Welfare Assessment  Volume II Book
Author : Edward Narayan,Alan G. McElligott
Publisher : Frontiers Media SA
Release : 2021-09-30
ISBN : 2889714284
Language : En, Es, Fr & De

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Book Description :

Download Animal Welfare Assessment Volume II book written by Edward Narayan,Alan G. McElligott, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Neural Control of Movement

The Neural Control of Movement Book
Author : Patrick J. Whelan,Simon A. Sharples
Publisher : Academic Press
Release : 2020-08-12
ISBN : 0128172754
Language : En, Es, Fr & De

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Book Description :

From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs. The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control. Provides practice details on model systems, approaches, and analysis approaches related to movement control Discusses how recent advances like optogenetics and chemogenetics affect the need for model systems to be modified (or not) to work for studies of movement and motor control Written for neuroscientists interested in movement control, especially movement disorders like Parkinson’s, MS, spinal cord injury, and stroke

Zebrafish

Zebrafish Book
Author : Christiane Nusslein-Volhard,Ralf Dahm
Publisher : Oxford University Press
Release : 2002-09-19
ISBN : 9780199638086
Language : En, Es, Fr & De

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Book Description :

The zebrafish has become one of the most important model organisms to study biologial processes in vivo. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiology and disease. The next few years will see the completion of large scale initiatives that exploit the zebrafish as a model system for the understanding of gene function in vertebrates, including the sequencing of the genome. The zebrafish will therefore play an increasingly important role in the future of biomedical research. Whole genome sequencing projects, such as the human genome project, have led to the isolation of tens of thousands of genes for which the in vivo function is unknown. It is therefore likely that an increasing number of researchers will turn to organisms such as the zebrafish to understand the in vivo requirement for the proteins these genes encode. Recent technical advances now allow the rapid testing of in vivo function of as yet uncharacterised genes in zebrafish in large numbers and at a speed that is impossible in other systems. This book not only provides a complete set of instructions that will allow researchers to establish the zebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.

Zebrafish Protocols for Neurobehavioral Research

Zebrafish Protocols for Neurobehavioral Research Book
Author : Allan V. Kalueff,Adam Michael Stewart
Publisher : Humana Press
Release : 2012-06-06
ISBN : 9781617795985
Language : En, Es, Fr & De

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Book Description :

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.

Antimicrobials and Anticancers of Bacterial Origins

Antimicrobials and Anticancers of Bacterial Origins Book
Author : Bingyun Li
Publisher : Frontiers Media SA
Release : 2020-06-26
ISBN : 2889638065
Language : En, Es, Fr & De

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Book Description :

Download Antimicrobials and Anticancers of Bacterial Origins book written by Bingyun Li, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances in Biomedical Sciences and Engineering

Advances in Biomedical Sciences and Engineering Book
Author : S. C. Tjong
Publisher : Bentham Science Publishers
Release : 2010-06-10
ISBN : 1608050408
Language : En, Es, Fr & De

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Book Description :

"This authoritative reference provides updated information on the fundamental aspects and applications of biomaterials and biomedical sciences. It includes nickel-titanium alloys with superelasticity and shape memory effect, bioactive bone cement for ortho"

Advancements of Mass Spectrometry in Biomedical Research

Advancements of Mass Spectrometry in Biomedical Research Book
Author : Alisa G. Woods,Costel C. Darie
Publisher : Springer
Release : 2019-07-25
ISBN : 3030159507
Language : En, Es, Fr & De

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Book Description :

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.

Computer Analysis of Images and Patterns

Computer Analysis of Images and Patterns Book
Author : Nicolas Tsapatsoulis,Andreas Panayides,Theo Theocharides,Andreas Lanitis,Constantinos Pattichis,Mario Vento
Publisher : Springer Nature
Release : 2021-10-31
ISBN : 3030891283
Language : En, Es, Fr & De

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Book Description :

The two volume set LNCS 13052 and 13053 constitutes the refereed proceedings of the 19th International Conference on Computer Analysis of Images and Patterns, CAIP 2021, held virtually, in September 2021. The 87 papers presented were carefully reviewed and selected from 129 submissions. The papers are organized in the following topical sections across the 2 volumes: 3D vision, biomedical image and pattern analysis; machine learning; feature extractions; object recognition; face and gesture, guess the age contest, biometrics, cryptography and security; and segmentation and image restoration.

DNA and Cell Biology

DNA and Cell Biology Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download DNA and Cell Biology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biology of Stress in Fish

Biology of Stress in Fish Book
Author : Carl B. Schreck,Lluis Tort,Anthony P. Farrell,Colin J. Brauner
Publisher : Academic Press
Release : 2016-11-01
ISBN : 0128027371
Language : En, Es, Fr & De

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Book Description :

Biology of Stress in Fish: Fish Physiology provides a general understanding on the topic of stress biology, including most of the recent advances in the field. The book starts with a general discussion of stress, providing answers to issues such as its definition, the nature of the physiological stress response, and the factors that affect the stress response. It also considers the biotic and abiotic factors that cause variation in the stress response, how the stress response is generated and controlled, its effect on physiological and organismic function and performance, and applied assessment of stress, animal welfare, and stress as related to model species. Provides the definitive reference on stress in fish as written by world-renowned experts in the field Includes the most recent advances and up-to-date thinking about the causes of stress in fish, their implications, and how to minimize the negative effects Considers the biotic and abiotic factors that cause variation in the stress response

The Clinical Chemistry of Laboratory Animals

The Clinical Chemistry of Laboratory Animals Book
Author : David M. Kurtz,Gregory S. Travlos
Publisher : CRC Press
Release : 2017-10-18
ISBN : 142009114X
Language : En, Es, Fr & De

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Book Description :

Key features: Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics Provides extensive reference lists at the end of each chapter to facilitate further study Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems. Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed. New Chapters in the Third Edition Include: The Laboratory Zebrafish and Other Fishes Evaluation of Cardiovascular and Pulmonary Function and Injury Evaluation of Skeletal Muscle Function and Injury Evaluation of Bone Function and Injury Vitamins Development of Biomarkers Statistical Methods The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species.