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The Value Of Bcg And Tnf In Autoimmunity

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The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmunity Book
Author : Denise Faustman
Publisher : Academic Press
Release : 2018-08-01
ISBN : 0081025904
Language : En, Es, Fr & De

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Book Description :

The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new prevention and treatment trials in autoimmunity and allergy, along with a new understanding of the genetics of BCGs. Brings a different perspective on treatment approaches for certain autoimmune conditions Gives insight into the how the BCG vaccine impacts gene expression and the durability of the BCG vaccines in long lasting clinic effects Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment Covers new topics, such as the Epigenetics of tuberculosis, BCG in neurological disease, BCG in early childhood and allergy, BCG in large prevention trials, Gene expression of BCG and re-methylation of genes, and more

The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmunity Book
Author : Denise Faustman
Publisher : Academic Press
Release : 2014
ISBN : 9780127999647
Language : En, Es, Fr & De

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Book Description :

The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity. Editor awarded 2005: Oprah Achievement Award," Top Health Breakthrough by a Female Scientist" Brings into one resource the international scientific literature on a unique way to treat autoimmunity Provides a different perspective on treatment approaches for certain autoimmune conditions Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment

Nutrition and Cardiovascular Health

Nutrition and Cardiovascular Health Book
Author : Paramjit S. Tappia,Heather Blewett
Publisher : MDPI
Release : 2020-06-17
ISBN : 3039288873
Language : En, Es, Fr & De

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Book Description :

There is unequivocal experimental, epidemiological, and clinical evidence demonstrating a correlation between diet and increased risk of cardiovascular disease (CVD). While nutritionally-poor diets can have a significant negative impact on cardiovascular health, dietary interventions with specific nutrients and/or functional foods are considered cost-effective and efficient components of prevention strategies. It has been estimated that nutritional factors may be responsible for approximately 40% of all CVD. Indeed, in one of the seminal studies conducted on modifiable risk factors and heart health (the INTERHEART study), >90% of all myocardial infarctions were attributed to preventable environmental factors with nutrition identified as one of the important determinants of CVD. There is an increasing public interest in and scientific investigation into establishing dietary approaches that can be undertaken for the prevention and treatment of CVD. This Special Issue provides an insight into the influential role of nutrition and dietary habits on cardiovascular health and disease, as well as their mechanisms of therapeutic and preventive action.

Heterologous Immunity Implications and Applications in Vaccines and Immunotherapies

Heterologous Immunity  Implications and Applications in Vaccines and Immunotherapies Book
Author : Babita Agrawal,Stephanie Yanow,Shakti Singh
Publisher : Frontiers Media SA
Release : 2020-08-27
ISBN : 2889639657
Language : En, Es, Fr & De

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Book Description :

Download Heterologous Immunity Implications and Applications in Vaccines and Immunotherapies book written by Babita Agrawal,Stephanie Yanow,Shakti Singh, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis Book
Author : Rupinder K. Sodhi,Jitender Madan
Publisher : Academic Press
Release : 2020-10-30
ISBN : 0128157631
Language : En, Es, Fr & De

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Book Description :

Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis

Vaccines and Autoimmunity

Vaccines and Autoimmunity Book
Author : Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic
Publisher : John Wiley & Sons
Release : 2015-05-11
ISBN : 1118663497
Language : En, Es, Fr & De

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Book Description :

In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

Immunopathogenesis and Immune based Therapy for Selected Autoimmune Disorders

Immunopathogenesis and Immune based Therapy for Selected Autoimmune Disorders Book
Author : Mourad Aribi
Publisher : BoD – Books on Demand
Release : 2017-03-22
ISBN : 9535130218
Language : En, Es, Fr & De

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Book Description :

The book Immunopathogenesis and Immune-Based Therapy for Selected Autoimmune Disorders is a synthesis work that discusses two main aspects of autoimmunity: Immunopathogenesis and therapeutic approaches essentially based on the immunotherapies. This book deals with different topics on a number of autoimmune disorders, including type 1 diabetes, autoimmune cardiomyopathy, autoimmunity of gastrointestinal tract, systemic sclerosis, and myasthenia gravis. This book will be useful to clinicians, biologists, researchers, teachers, and students who are interested in immunology and immunopathology.

Infections in Systemic Autoimmune Diseases Risk Factors and Management

Infections in Systemic Autoimmune Diseases  Risk Factors and Management Book
Author : Anonim
Publisher : Elsevier
Release : 2020-03-08
ISBN : 0444642188
Language : En, Es, Fr & De

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Book Description :

Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who’s who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on Infection problems in systemic autoimmune diseases Provides a practical guide to the safer treatment of infections in patients with autoimmune diseases Includes a number of problems and recommendation that cannot be found in other books Designed as a ‘guide to clinical practice’ for management and risk interventions required by patients with SAD’s

Melanoma An Issue of Surgical Oncology Clinics of North America

Melanoma  An Issue of Surgical Oncology Clinics of North America  Book
Author : Adam C. Berger
Publisher : Elsevier Health Sciences
Release : 2015-06-03
ISBN : 032337011X
Language : En, Es, Fr & De

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Book Description :

This issue of Surgical Oncology Clinics of North America, edited by Adam Berger, is devoted to Melanoma. Articles in this issue include: Current Staging and Prognostic Factors in Melanoma; Melanoma Pathology; Surgical Treatment of Primary and Recurrent Melanoma; Sentinel Lymph Node Mapping and Its Importance for Melanoma in the 21st Century; Lymph Node Dissection for Stage 3 Melanoma; Metastasectomy for Stage IV Melanoma; Local/Injectional Therapies for Satellite and In-Transit Disease; Regional Therapies for In-Transit Disease; Role for Radiation Therapy in Melanoma; Update on Immunotherapy for Melanoma; Targeted Therapies in Melanoma; and Evidence for Long-Term Follow-up of Melanoma Patients.

Mycobacterial Infection and Autoimmune Diesease in the Central Nervous System

Mycobacterial Infection and Autoimmune Diesease in the Central Nervous System Book
Author : JangEun Lee
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Mycobacterial Infection and Autoimmune Diesease in the Central Nervous System book written by JangEun Lee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Vaccines

Molecular Vaccines Book
Author : Matthias Giese
Publisher : Springer Science & Business Media
Release : 2013-11-08
ISBN : 3319009788
Language : En, Es, Fr & De

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Book Description :

This title discusses all aspects of non-infectious and non-cancer– so called NINC – vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug Administration) guidelines are described in-depth. The book is therefore of interest for researchers and clinicians engaged in vaccine development and molecular vaccine application.

European Cytokine Network

European Cytokine Network Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download European Cytokine Network book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Vascular Manifestations of Systemic Autoimmune Diseases

Vascular Manifestations of Systemic Autoimmune Diseases Book
Author : Ronald A. Asherson,Ricard Cervera,Douglas A. Triplett,Steven B. Abramson
Publisher : CRC Press
Release : 2001-01-25
ISBN : 9781420040395
Language : En, Es, Fr & De

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Book Description :

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all

Behavior of a Small T Cell Network in BCG Infection

Behavior of a Small T Cell Network in BCG Infection Book
Author : Dominic Oliver So Co
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Behavior of a Small T Cell Network in BCG Infection book written by Dominic Oliver So Co, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Autoimmune Endocrinopathies

Autoimmune Endocrinopathies Book
Author : Robert Volpé
Publisher : Springer Science & Business Media
Release : 1999-06-04
ISBN : 1592597041
Language : En, Es, Fr & De

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Book Description :

Dr. Robert Volpé and his distinguished contributors comprehensively review the latest thinking about the theoretical, experimental, and clinical aspects of autoimmune endocrine disorders. These world-renowned experts examine the pathogenesis and immunogenetics of these diseases, discuss the role of sex hormones in autoimmunity, and elucidate the nature of autoantigens. They also provide clinical detail on a wide variety of autoimmune endocrinopathies, including autoimmune thyroid disease, Graves' ophthalmopathy and dermopathy, human insulin-dependent diabetes mellitus, and autoimmune adrenocortical failure. Postpartum autoimmune endocrine syndromes, autoimmune hypophysitis, and the polyglandular autoimmune syndromes are also discussed in detail. Comprehensive and authoritative, Autoimmune Endocrinopathies provides today's most up-to-date understanding of the etiology and pathogenesis of autoimmune endocrine diseases.

Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments

Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments Book
Author : Anne C. La Flamme,Jacqueline Monique Orian
Publisher : Springer
Release : 2015-10-07
ISBN : 3319255436
Language : En, Es, Fr & De

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Book Description :

Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.

Abridged Index Medicus

Abridged Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Abridged Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

AIDS Bibliography

AIDS Bibliography Book
Author : Anonim
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download AIDS Bibliography book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Primary Immunodeficiencies Worldwide

Primary Immunodeficiencies Worldwide Book
Author : Menno C. van Zelm,Antonio Condino-Neto,Mohamed-Ridha Barbouche
Publisher : Frontiers Media SA
Release : 2020-02-19
ISBN : 2889635201
Language : En, Es, Fr & De

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Book Description :

Download Primary Immunodeficiencies Worldwide book written by Menno C. van Zelm,Antonio Condino-Neto,Mohamed-Ridha Barbouche, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Journal of Immunology

The Journal of Immunology Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Journal of Immunology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.