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The Significance Of The Interleukin 18 In The Mouse Central Nervous System

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The Significance of the Interleukin 18 in the Mouse Central Nervous System

The Significance of the Interleukin 18 in the Mouse Central Nervous System Book
Author : Claudia Montanari
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Significance of the Interleukin 18 in the Mouse Central Nervous System book written by Claudia Montanari, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Protective and Pathological Immune Responses in the CNS

Protective and Pathological Immune Responses in the CNS Book
Author : B. Dietzschold,J.A. Richt
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 3662095254
Language : En, Es, Fr & De

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Book Description :

In spite of the protection of the CNS there are situations where immune responses occur due to different disease processes. While antigen-specific cells of the adaptive immune response are not normally functional in the CNS tissue, CNS resident cells respond to infection or insult. One mechanisms is through the induction of apoptosis in virus infected neurons, which may be protective or pathogenic depending on the extent of cell death.

Inflammatory Disorders of the Nervous System

Inflammatory Disorders of the Nervous System Book
Author : Alireza Minagar,J. Steven Alezander
Publisher : Springer Science & Business Media
Release : 2007-10-28
ISBN : 1592599052
Language : En, Es, Fr & De

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Book Description :

A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.

Central Nervous System Diseases and Inflammation

Central Nervous System Diseases and Inflammation Book
Author : Thomas E. Lane,Monica Carson,Conni Bergmann,Tony Wyss-Coray
Publisher : Springer Science & Business Media
Release : 2007-12-24
ISBN : 0387738940
Language : En, Es, Fr & De

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Book Description :

Edited and authored by top names in the field, this book provides a succinct reference on inflammatory central nervous system disease. It focuses on current areas of investigation in the fields of neuroimmunology, virology, pharmacology, and disease. Sections focus on specific categories of diseases, examining the pharmacological, virological, and immunological effects of and on the disease. This book’s unique organization provides a concise overview of inflammatory CNS disease.

Cytokines and the CNS

Cytokines and the CNS Book
Author : Richard M. Ransohoff,Etty N. Benveniste
Publisher : CRC Press
Release : 2005-10-31
ISBN : 1420039849
Language : En, Es, Fr & De

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Book Description :

Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelerating interest in cytokines and cytokine/chemokine signaling over the past several years has encouraged an explosion of literature on cytokines. The similarity between factors involved in inflammation or immunity, and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in the neurobiologist’s cognitive tool-kit. Conversely, for immunobiologists, the concepts elaborated by neurobiologists to understand developmental patterning and networked organ function continue to evolve in such a way that comprehension of cytokine action in the CNS can only enhance a further understanding of immune system function. Cytokines and the CNS, Second Edition is patterned after the first edition; however, the wealth of knowledge now available adds a tremendous amount of insight and new implications. To guarantee a fresh perspective, the editors made a conscious choice to utilize an entirely new set of contributors, all experts in various aspects of cytokine research. Cytokines and the CNS, Second Edition starts with a chapter on the CNS, focusing on pathological reactions to insult. Next, come three chapters on cytokine biology, followed by four chapters that integrate cytokine biology into basic CNS processes (development; inflammation; immunity; degeneration/repair), after which five chapters apply this body of knowledge to disease or pathology. The book closes with a look at the application of cytokine biology to the treatment of disease, a brand new area of research.

Microglia in the Regenerating and Degenerating Central Nervous System

Microglia in the Regenerating and Degenerating Central Nervous System Book
Author : Wolfgang J. Streit
Publisher : Springer Science & Business Media
Release : 2013-03-14
ISBN : 1475741391
Language : En, Es, Fr & De

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Book Description :

The study of microglial cells has recently gained importance for those researching degeneration and regeneration. Microglia in the regenerating and degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and reviews their cell function and physiology.

Fundamental Immunology

Fundamental Immunology Book
Author : William E. Paul
Publisher : Lippincott Williams & Wilkins
Release : 2012-12-03
ISBN : 1451182031
Language : En, Es, Fr & De

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Book Description :

This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank! This is the tablet version of Fundamental Immunology which does not include access to the supplemental content mentioned in the text.

Neuroglia

Neuroglia Book
Author : Bruce R. Ransom
Publisher : Oxford University Press
Release : 2012-11-29
ISBN : 0199794731
Language : En, Es, Fr & De

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Book Description :

Neuroglia, the third edition, is the long-awaited revision of the most highly regarded reference volume on glial cells. This indispensable edition has been completely revised, greatly enlarged, and enhanced with four-color figures throughout, all in response to the tremendous amount of new information that has accumulated since the previous edition seven years ago. Glial cells are, without doubt, the new stars in the neuroscience and neurology communities. Neglected in research for years, it is now evident that the brain only functions in a concerted action of all the cells, namely glia and neurons. Seventy one chapters comprehensively discuss virtually every aspect of normal glial cell anatomy, physiology, biochemistry and function, and consider the central roles of these cells in neurological diseases including stroke, Alzheimer disease, multiple sclerosis, Parkinson's disease, neuropathy, and psychiatric conditions. More than 20 new chapters have been added to accommodate the unprecedented growth of knowledge about the basic biology of glia and the sophisticated manner in which they partner with neurons in the course of normal brain function. Lavishly illustrated and meticulously edited, the third edition remains the most convenient and maximally useful reference available. This new edition is an essential reference for both newcomers to the field as well as established investigators. Neuroglia belongs on every neuroscientist's bookshelf and will be a great asset for educators and neurological clinicians as well.

Metabolic Engineering

Metabolic Engineering Book
Author : Jens Høiriis Nielsen,Jens Nielsen,L. Eggeling
Publisher : Springer Science & Business Media
Release : 2001
ISBN : 9783540418481
Language : En, Es, Fr & De

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Book Description :

Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Inflammation and Stroke

Inflammation and Stroke Book
Author : Giora Z. Feuerstein
Publisher : Springer
Release : 2012-12-06
ISBN : 3034882971
Language : En, Es, Fr & De

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Book Description :

Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.

Cytokine Knockouts

Cytokine Knockouts Book
Author : Giamila Fantuzzi
Publisher : Springer Science & Business Media
Release : 2003-07-30
ISBN : 1592594050
Language : En, Es, Fr & De

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Book Description :

Carrying on the high standards of the much praised first edition (Durum and Muegge, Cytokine Knockouts, 1998), Giamila Fantuzzi and a panel of experts have generated completely new chapters to reflect the use of many novel mouse strains and the hundreds of recent studies on cytokine physiology. Comprehensive reviews of the numerous often-surprising results obtained using cytokine knockout mice are provided, along with much important information about cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research.

The Journal of Cell Biology

The Journal of Cell Biology Book
Author : Anonim
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

No. 2, pt. 2 of November issue each year from v. 19-47; 1963-70 and v. 55- 1972- contain the Abstracts of papers presented at the annual meeting of the American Society for Cell Biology, 3d-10th; 1963-70 and 12th- 1972- .

Cytokines and Pain

Cytokines and Pain Book
Author : Waldiceu A. Verri,Felipe Almeida Pinho-Ribeiro,Larissa G. Pinto
Publisher : Frontiers Media SA
Release : 2021-12-28
ISBN : 2889718603
Language : En, Es, Fr & De

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Book Description :

Download Cytokines and Pain book written by Waldiceu A. Verri,Felipe Almeida Pinho-Ribeiro,Larissa G. Pinto, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Neuroimmunology

Clinical Neuroimmunology Book
Author : Jack P. Antel
Publisher : Oxford University Press, USA
Release : 2005
ISBN : 0198510683
Language : En, Es, Fr & De

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Book Description :

Provides broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches to disease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. Chapters are dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to a whole array of immune-directed therapies.

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in Epilepsy Research

Recent Advances in Epilepsy Research Book
Author : Devin K. Binder,Helen E. Scharfman
Publisher : Springer Science & Business Media
Release : 2013-03-14
ISBN : 147576376X
Language : En, Es, Fr & De

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Book Description :

Epilepsy research has entered an exciting phase as advances in molecular analysis have supplemented in vitro and in vivo electrophysiologic and phenotypic characterization. Recent Advances in Epilepsy Research sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry. Key features: neurogenetics of seizure disorders, new developments in cellular and molecular neurobiology of seizure disorders, the role of growth factors in seizures, new advances in the roles of metabotropic glutamate receptors and GABA receptors and transporters, gap junctions, neuroimmunology of epilepsy, malformations of cortical development, neurogenesis, new animal models of epilepsy and the use of brain stimulation to treat epilepsy. This book should be of interest to a wide variety of audiences, including graduate students in neurobiology and related disciplines, neuroscientists, medical students, neurologists, neurosurgeons, and industry including pharmaceutical companies and medical device companies. There are many ideas in this book that will lead ingenious innovators in academia and industry to develop new and better therapies.

Advances in Nervous System Research and Application 2011 Edition

Advances in Nervous System Research and Application  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464920664
Language : En, Es, Fr & De

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Book Description :

Advances in Nervous System Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nervous System. The editors have built Advances in Nervous System Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nervous System in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nervous System Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Sabiston Textbook of Surgery E Book

Sabiston Textbook of Surgery E Book Book
Author : Courtney M. Townsend
Publisher : Elsevier Health Sciences
Release : 2021-01-08
ISBN : 0323640648
Language : En, Es, Fr & De

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Book Description :

For more than 80 years, Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice has been the go-to text for trainees and surgeons at all levels of experience for definitive guidance on every aspect of general surgery. As the oldest continuously published textbook of surgery in North America, this fully revised 21st Edition continues to provide the key information, essential teaching pearls, and completely updated content needed to make the most informed surgical decisions and achieve optimal outcomes for patients. Concisely written and evidence based throughout, it covers the breadth of material required for certification and practice of general surgery, highlighted by detailed, full-color intraoperative illustrations and high-quality video clips. Follows a clear, consistent progression beginning with principles common to surgical specialties including fluid and electrolyte management, metabolic support, and wound healing. Subsequent sections review the management of injury, transplantation, oncology, breast, endocrine, and abdominal procedures. Covers key topics such as emerging surgical technologies and devices, regenerative medicine, the latest concepts in cancer biology and treatments, and evidence-based management and treatment. Emphasizes the most up-to-date minimally invasive techniques and the use of robotics when indicated. Features more than 2,000 superb illustrations and intraoperative photographs and 25 procedural videos that facilitate quick comprehension of surgical techniques. Includes more schematic diagrams, summary tables, boxes, and algorithms that provide a rich resource for reviewing surgical techniques and preparing for in-training and board exams. Shares the expertise of dozens of new authors and includes two new chapters on robotic surgery and fetal surgery. Contains fully updated content on topics encountered by general surgery residents in training as well as in-depth coverage of subspecialty areas including head and neck, thoracic, vascular, urology, neurosurgery, pediatrics, and gynecology.

Handbook of Experimental Neurology

Handbook of Experimental Neurology Book
Author : Turgut Tatlisumak,Marc Fisher
Publisher : Cambridge University Press
Release : 2006-10-05
ISBN : 1139459759
Language : En, Es, Fr & De

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Book Description :

Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. Originally published in 2006, this important reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in neuroscience research. Divided into two major sections, the first deals with general methodologies in neuroscience research covering topics from animal welfare and ethical issues to surgical procedures, post-operative care and behavioral testing. Section two covers every major disease model including traumatic brain injury, ischemia and stroke, to Parkinson's, motor neurone disease, epilepsy and sleep disorders. Delivering critical methodological information and describing small animal models for almost all major neurological diseases, this book forms an essential reference for anyone working in neuroscience, from beginning students to experienced researchers and medical professionals.

Glial Cell Function Paperback

Glial Cell Function  Paperback  Book
Author : Bernardo Castellano,B. Castellano Lopez,M. Nieto-Sampedro
Publisher : Gulf Professional Publishing
Release : 2003-09-29
ISBN : 9780444514868
Language : En, Es, Fr & De

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Book Description :

Although knowledge of the development and differentiation of glial cells has significantly increased in recent years, there are still many questions unanswered. The first section of the book is devoted to this very active topic and includes contributions on Schwann cells, oligodendrocytes, astroglia and microglia. The second section of the book covers cellular interactions, the role they play on myelination and remyelination, how these interactions take place and the molecules involved. The third section of this volume focuses on the interactions of neurons with glial cells and their role in brain function. Neuron-glia cross talk appears to be fundamental for synaptic transmission and several chapters in this section address this topic. The topic of how glial cells react to brain injury and how they participate in neuroprotection and brain repair is covered in section four of this book. As our knowledge about the molecules involved in the regenerative properties of glia increases, new avenues are open for the use of genetically modified glia with therapeutic purposes. The final section of the book is devoted to therapeutic approaches to tumours, viral and prion infections. Gene therapy is a promising approach for the treatment of gliomas, one of the most devastating forms of cancer. A chapter on prion diseases and microglia addresses a question of tremendous actuality, since prion diseases in cows is at this moment the major veterinary problem in Europe and has created a considerable social alarm.