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The Neuroscience Of Autism Spectrum Disorders

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The Neuroscience of Autism Spectrum Disorders

The Neuroscience of Autism Spectrum Disorders Book
Author : Joseph D. Buxbaum,Patrick R. Hof
Publisher : Academic Press
Release : 2012-12-31
ISBN : 0123919304
Language : En, Es, Fr & De

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Book Description :

Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

The Neuroscience of Autism Spectrum Disorders

The Neuroscience of Autism Spectrum Disorders Book
Author : Joseph D. Buxbaum,Patrick R. Hof
Publisher : Academic Press
Release : 2012-10-25
ISBN : 012391924X
Language : En, Es, Fr & De

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Book Description :

Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available

Autism Spectrum Disorder

Autism Spectrum Disorder Book
Author : Susan P. Sherkow,Alexandra M. Harrison , M.D.
Publisher : Rowman & Littlefield
Release : 2013-11-14
ISBN : 0765708639
Language : En, Es, Fr & De

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Book Description :

Autism Spectrum Disorder: Perspectives from Psychoanalysis and Neuroscience, offers a guide to understanding and treating the ASD toddler from the dual perspectives of psychoanalysis and neurofunction through describing in great detail intensive treatments of four children who began therapy as toddlers. The authors hypothesize that dyadic therapy and Reflective Network Therapy can impact a child by modifying the biochemistry of the brain, resulting in alteration of emotion and cognition. Their chapter on neurobiological mechanisms of change describes these hypotheses in depth.

The Neuroscience of Autism

The Neuroscience of Autism Book
Author : Rajesh K. Kana
Publisher : Academic Press
Release : 2022-05-27
ISBN : 012816736X
Language : En, Es, Fr & De

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Book Description :

The Neuroscience of Autism provides a comprehensive accounting of autism spectrum disorders by integrating scientific findings from behavioral, cognitive and neurobiological research. The book begins by defining autism, identifying characteristics and prevalence, exploring its history, and then moving on to the cognitive and social bases of behavioral symptoms, the brain bases of behavioral and cognitive symptoms, and finally, intervention practices. It examines theoretical models such as weak central coherence, enhanced perceptual functioning, and the extreme male brain hypothesis. Finally, the book addresses the increased attention on the brain connectivity model of autism, looking at the synchronization of brain activity across different brain areas, the causal influence of a brain region on another, and white matter cable connections in the brain. Delves into the increasing prevalence of autism in the United States Focuses on screening tools for early identification Discusses the neuroanatomical differences seen in individuals with autism Examines the inferences gained from functional MRI studies of autism

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability Book
Author : Carlo Sala,Chiara Verpelli
Publisher : Academic Press
Release : 2016-04-30
ISBN : 0128005335
Language : En, Es, Fr & De

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Book Description :

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture

Understanding Children with Autism Spectrum Disorders

Understanding Children with Autism Spectrum Disorders Book
Author : Anne Bourque
Publisher : Nova Science Publishers
Release : 2020
ISBN : 9781536176483
Language : En, Es, Fr & De

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Book Description :

"Understanding Children with Autism Spectrum Disorders first discusses auditory processing disorders are, specifically how auditory processing problems can affect children with autism spectrum disorders, and appropriate evidence-based treatments. The authors highlight the challenges associated with making a dual diagnosis, and discuss specific anatomical differences in the central auditory pathway and brain. Also highlighted is the need for improved research on intervention programs and the important service needs for families and children with autism spectrum disorders. A study is presented wherein pediatric volition among children with autism spectrum disorders participating in the Holland Bloorview (HB) FIRST® robotics program is measured. A review is carried out in order to describe the main neurotransmitters in autism spectrum condition patients. Among the studied neurotransmitters, increased serotonin and glutamate as well as decreased levels of gamma-aminobutyric acid N-Acetylaspartate and oxytocin appear to have the most empirical evidence. The authors assess the relationship between autism spectrum disorder symptomatology, theory of mind, and other individual factor on children's responses through a study attempting to determine the factors that contribute to the complexity of the emotion of embarrassment. The closing study addresses that with respect to dietary issues, awareness of the eating habits and feeding problems experienced by autism spectrum disorder children needs to be emphasized among parents and guardians"--

Homeostatic Control of Brain Function

Homeostatic Control of Brain Function Book
Author : Detlev Boison,Susan Masino
Publisher : Oxford University Press
Release : 2016
ISBN : 0199322295
Language : En, Es, Fr & De

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Book Description :

Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Autism Spectrum Disorder

Autism Spectrum Disorder Book
Author : Susan P. Sherkow,Alexandra Harrison
Publisher : Jason Aronson
Release : 2013-11-11
ISBN : 9780765708625
Language : En, Es, Fr & De

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Book Description :

Autism Spectrum Disorder: Perspectives from Psychoanalysis and Neuroscience, offers a guide to understanding and treating the ASD toddler from the dual perspectives of psychoanalysis and neurofunction through describing in great detail intensive treatments of four children who began therapy as toddlers. The authors hypothesize that dyadic therapy and Reflective Network Therapy can impact a child by modifying the biochemistry of the brain, resulting in alteration of emotion and cognition. Their chapter on neurobiological mechanisms of change describes these hypotheses in depth.

Autism Spectrum Disorder

Autism Spectrum Disorder Book
Author : Michael Fitzgerald
Publisher : BoD – Books on Demand
Release : 2021-06-09
ISBN : 1838810056
Language : En, Es, Fr & De

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Book Description :

Autism spectrum disorder (ASD) is a complex condition that has extreme heterogeneity, which makes it extremely challenging from a diagnostic and etiological point of view. To add to the complexity, ASD typically has co-morbidity and overlap with other conditions outlined in this book, including epilepsy, attention-deficit/hyperactivity disorder (ADHD), and others. This book also examines monocyte cytokine profiles and catecholamines in ASD, genetic studies of autism, treatments, and controversial issues.

Neurobiology of Autism

Neurobiology of Autism Book
Author : Anonim
Publisher : Elsevier
Release : 2013-11-27
ISBN : 0124199615
Language : En, Es, Fr & De

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Book Description :

This volume in the International Review of Neurobiology is a comprehensive overview of the state-of-the-art research into autism pathophysiology. Its chapters cover a wide range of etiologies, from genetics and development to environmental factors. In addition, it discusses key cell and behavioral phenotypes, including cortical and cerebellar phenotypes, as well as language and motor outputs. Finally, this volume's chapters on gene expression in the brain describe how genes may be connected to phenotypes in autism. Broad coverage of genetic and cellular phenotypes in autism Focused on basic research Chapters primarily written by new investigators with a fresh perspective on the biological underpinnings of autism

Biometals in Autism Spectrum Disorders

Biometals in Autism Spectrum Disorders Book
Author : Andreas Grabrucker
Publisher : Academic Press
Release : 2020-07-08
ISBN : 0128211334
Language : En, Es, Fr & De

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Book Description :

Biometals in Autism Spectrum Disorders focuses on trace metals and autism. Compared to other references examining ASDs or metallomics, this book presents findings of abnormal metal homeostasis in ASD, providing an overview of current findings on trace metal biology, its role in ASD etiology, and how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs that were once considered unrelated. This comprehensive resource opens new vistas for the development of new therapies based on the targeted manipulation of trace metal homeostasis that will generate new awareness surrounding trace metal levels during pregnancy. Reviews the role of trace metals in brain development Summarizes research linking trace metals and autism Explores heterogenous phenotypes as a factor of genetic and non-genetic factors Includes animal and human stem research Contains many useful diagrams, tables and flow charts Proposes future therapies based on biometal homeostasis

Neuroimaging in Developmental Clinical Neuroscience

Neuroimaging in Developmental Clinical Neuroscience Book
Author : Judith M. Rumsey,Monique Ernst
Publisher : Cambridge University Press
Release : 2009-02-19
ISBN : 9781139476751
Language : En, Es, Fr & De

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Book Description :

Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.

Autism Spectrum Disorder

Autism Spectrum Disorder Book
Author : Michael Fitzgerald
Publisher : BoD – Books on Demand
Release : 2015-04-02
ISBN : 9535120379
Language : En, Es, Fr & De

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Book Description :

This book starts with a new sub category of Autism Criminal Autistic Psychopathy and school shootings. It focuses on a number of interventions, including speech and language pathology, speech and language assessment instruments, occupational therapy, improving functional language development in autism with natural gestures, communication boards etc as well as helping people with autism using the pictorial support, training of concepts of significant others, theory of mind, social concepts and a conceptual model for empowering families of children with autism cross culturally. It also examines the issue of hyperandrogenism and evidence-based treatments of autism. In terms of assessment, it focuses on psychological and biological assessment including neurotransmitters systems, structural and functional brain imaging, coping strategies of parents, examines the intertwining of language impairment, specific language impairment and ASD, as well as implicit and spontaneous Theory of Mind reading in ASD. In terms of aetiology, it focuses on genetic factors, epigenetics, synaptic vesicles, toxicity during neurodevelopment, immune system and sex differences. It also examines the link between social cognitive anatomical and neurophysiologic biomarkers and candidate genes. This book will be relevant to all mental health professionals because autism occurs in all the different areas of psychiatry and professionals who will find it helpful will be psychiatrists, psychologists, social workers, nurses, teachers and all those working with persons with Autism including parents who nowadays are interested in knowing more and more, at a detailed level about their children or adults with autism.

The Neurobiology of Autism

The Neurobiology of Autism Book
Author : Margaret L. Bauman,Thomas L. Kemper
Publisher : JHU Press
Release : 2005
ISBN : 9780801880476
Language : En, Es, Fr & De

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Book Description :

For this long-anticipated new edition, neurologists Margaret L. Bauman and Thomas L. Kemper bring together leading researchers and clinicians to present the most current scientific knowledge and theories about autism. "Anyone doing research in autism or other developmental disorders will find this an invaluable book to read to make sure all areas are understood and to serve as a rich source of references." -- American Journal of Psychiatry

Autism Spectrum Disorders

Autism Spectrum Disorders Book
Author : David Amaral,Geraldine Dawson,Daniel Geschwind
Publisher : OUP USA
Release : 2011-06-17
ISBN : 0195371828
Language : En, Es, Fr & De

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Book Description :

Information about the symptoms, treatment, and research on Autism spectrum disorders including Autism and Asperger syndrome.

Recent Advances in Autism Spectrum Disorders

Recent Advances in Autism Spectrum Disorders Book
Author : Michael Fitzgerald
Publisher : BoD – Books on Demand
Release : 2013-03-06
ISBN : 9535110225
Language : En, Es, Fr & De

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Book Description :

The pace of research on Autism Spectrum Disorders (ASD) has expanded exponentially in recent years. It is difficult for anyone to keep up with all developments. This book will assist the experienced and non-specialist reader to keep up with recent developments. The book opens with a focus on the evolutionary aspects of autism and then focuses on the public's attitude towards autism including the stigma issue. Then there is a focus on cortical modularity and electrophysiology followed by treatment issues including sensory, medical and community-based interventions. Finally, forensic issues are dealt with and the importance of the built environment is focused on. The book will be relevant to psychiatrists, psychologists, paediatricians, social workers, speech and language therapists, occupational therapists and care workers.

Cognitive Plasticity in Neurologic Disorders

Cognitive Plasticity in Neurologic Disorders Book
Author : Joseph I. Tracy,Benjamin M. Hampstead,K. Sathian
Publisher : Oxford University Press, USA
Release : 2014-12-02
ISBN : 0199965242
Language : En, Es, Fr & De

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Book Description :

This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Autism and the Myth of the Person Alone

Autism and the Myth of the Person Alone Book
Author : Douglas Biklen,Larry Bissonnette,Lucy Blackman
Publisher : NYU Press
Release : 2005-08
ISBN : 9780814799277
Language : En, Es, Fr & De

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Book Description :

The prevailing view of autism and disability is redefined in this beautifully written book.

Autism Spectrum Disorder

Autism Spectrum Disorder Book
Author : Jill M. Boucher
Publisher : SAGE
Release : 2017-02-15
ISBN : 1473986990
Language : En, Es, Fr & De

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Book Description :

Following on from the popular and provocative First Edition, the Second Edition offers the latest research on autistic spectrum disorders, exploring theories at the psychological, neurobiological and 'first cause' levels to methods of assessment, intervention, education and support.

Behavioral Neuroscience

Behavioral Neuroscience Book
Author : Sara Palermo,Rosalba Morese
Publisher : BoD – Books on Demand
Release : 2019-12-18
ISBN : 1789840511
Language : En, Es, Fr & De

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Book Description :

What do we mean by "behavioral neuroscience?" This volume aims at providing an overview of behavioral neuroscience and deepening neuronal mechanisms and brain circuits that regulate the fundamental aspects of human behavior, such as cognitive and emotional functions. It is intended to give the reader the most up-to-date vision of how the interaction between biological mechanisms and neurocognitive processes leads to complex and highly organized behaviors.In recent years the strong impulse given to research on behavioral neuroscience has produced a large literature that documents the high level of complexity of the issue, for which it is necessary to provide a reasoned multidimensional analysis able to integrate the expertise of different disciplines.The book offers an excellent synopsis of perspectives, methods, empirical evidences, and international references. Therefore, it represents an extraordinary opportunity to target neuroscientific hot topics and to outline new horizons in the study of the relationship between brain and behavior.