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The Neurobiology Of Bipolar Disorder

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Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder Book
Author : Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta
Publisher : Academic Press
Release : 2020-11-27
ISBN : 012819183X
Language : En, Es, Fr & De

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Book Description :

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder Book
Author : Joao Luciano de Quevedo, MD, PhD,Andre Ferrer Carvalho, M.D., Ph.D.,Eduard Vieta
Publisher : Academic Press
Release : 2020-12-11
ISBN : 0128191821
Language : En, Es, Fr & De

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Book Description :

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Bipolar Depression Molecular Neurobiology Clinical Diagnosis and Pharmacotherapy

Bipolar Depression  Molecular Neurobiology  Clinical Diagnosis and Pharmacotherapy Book
Author : Carlos A. Zarate Jr.,Husseini K. Manji
Publisher : Springer Science & Business Media
Release : 2009-04-16
ISBN : 3764385677
Language : En, Es, Fr & De

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Book Description :

Although our knowledge of mood disorders is expanding, comparatively little is known about bipolar depression in particular. This book offers the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression. Early chapters provide diagnostic information and review the course, outcome and genetics of this heritable condition. The book gives a thorough and unique overview of the neurobiology of the disorder, including neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women. Furthermore, the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment, are addressed. Finally, acute and long-term treatment strategies for bipolar depression are discussed, including both traditional and novel therapeutics, as well as non-pharmacological treatments. This volume offers researchers and clinicians key insights into this devastating disorder.

Behavioral Neurobiology of Bipolar Disorder and its Treatment

Behavioral Neurobiology of Bipolar Disorder and its Treatment Book
Author : Husseini K. Manji,Carlos A. Zarate Jr.
Publisher : Springer Science & Business Media
Release : 2010-11-10
ISBN : 9783642157578
Language : En, Es, Fr & De

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Book Description :

This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Bipolar Depression

Bipolar Depression Book
Author : Rif S. El-Mallakh,S. Nassir Ghaemi
Publisher : American Psychiatric Pub
Release : 2007-04-02
ISBN : 9781585626519
Language : En, Es, Fr & De

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Book Description :

Although depression is the most common presentation of bipolar disorder, correct diagnosis generally requires a history of mania and thus presents a formidable challenge. This book provides clinicians with the necessary guidance to distinguish this illness and pursue an appropriate therapeutic course. It brings together a team of clinical investigators who offer cutting-edge research on the topic and address the most critical concerns regarding its treatment. Bipolar Depression first introduces a hierarchical model for diagnosis to allow the clinician to distinguish between bipolar and unipolar depression, addressing problems of misdiagnosis and overdiagnosis as well as differentiating attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. Early chapters review the neurobiology and genetics of this highly heritable condition, presenting studies of neurotransmitter function and brain imaging studies and documenting the susceptibility of specific chromosomes as loci for bipolar disorder. Other chapters address the particular issues of bipolar depression in children, for whom a diagnosis is especially problematic, and suicide, focusing on the need for assessment during both acute and maintenance treatment with interventions appropriate to a patient's symptoms and history. Bipolar Depression offers critiques of specific treatment approaches: Lithium and antiepileptic drugs: featuring a review of the most recent research on the use of lithium, in which higher doses are shown to be effective, plus coverage of lamotrigine, valproic acid, carbamazepine, oxcarbazepine, and topiramate. Antidepressants: offering new perspectives on a complex field, including a discussion of the randomized clinical trial literature and observational studies on their use, and citing cautions regarding side effects. Antipsychotics: evaluating the difference between first- and second-generation medications and discussing their role in controlling acute depressions. Novel approaches to treatment: including the use of atypical neuroleptics, electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, ketogenic diet, omega-3 fatty acids, myo-inositol, and dopamine agonists. Psychological interventions: focusing on the inclusion of cognitive-behavioral therapy or interpersonal social rhythm therapy for nonmelancholic depressions in patients who had previously received psychoeducation. Despite the past decade's advances in practice and research, there remains much room for progress in understanding and treating bipolar depression. This book blazes a trail toward that goal, opening new doors in recognizing differences between bipolar and unipolar forms of depression while offering both researchers and clinicians key insights into this troubling illness.

Bipolar Disorder

Bipolar Disorder Book
Author : Lakshmi N. Yatham,Mario Maj
Publisher : John Wiley & Sons
Release : 2011-06-28
ISBN : 1119956226
Language : En, Es, Fr & De

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Book Description :

Bipolar disorder is the most complex psychiatric disorder with different types of mood episodes, subtypes, varied course, and significant co-morbidity. Not surprisingly, this complexity poses unique challenges to clinicians for optimal management of those with bipolar disorder. There has been an explosion of research into the causes and treatment of this condition over the past two decades. It is a daunting task for a practising clinician to make sense of this research and to remain up to date with progress in the understanding of the neurobiology and treatment of bipolar disorder. This book synthesizes and translates the vast array of research knowledge into information that is clinically relevant and meaningful for a clinician. The book provides a comprehensive, yet focused, reference work on bipolar disorder for both trainees and practising psychiatrists. The two editors are leaders in the field who have published extensively on bipolar disorder. They have assembled a team of experts from around the world: in many instances, chapters are co-authored by people from different continents, bringing a truly international perspective to this important topic. The book covers the basic science of the pathology underlying bipolar disorder but addresses the clinical aspects of the disease throughout. The book comprises four sections: Descriptive Aspects—issues ranging from how the concept of bipolar disorder has evolved over the years to new information about neurocognitive impairment, creativity and economic productivity, and to discussion of the deliberations of the DSM-V committee on changes in diagnostic categories and criteria. Biology—the contribution of genes to this disorder, changes in circadian rhythms, what we know about brain changes and the role of oxidative stress. Biological Treatment and Psychosocial Treatment— all the latest information about pharmacological and psychological treatments and the optimal management of this condition. If you want to provide state-of-the-art care to your bipolar patients, be sure to consult this authoritative reference.

Neurobiology of Mental Illness

Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Eric J. Nestler,Pamela Sklar,Joseph D. Buxbaum
Publisher : Oxford University Press
Release : 2013-07-04
ISBN : 0199934959
Language : En, Es, Fr & De

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Book Description :

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Neurobiology of Depression

Neurobiology of Depression Book
Author : Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate
Publisher : Academic Press
Release : 2019-01-03
ISBN : 0128133341
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

The Bipolar Book

The Bipolar Book Book
Author : Aysegul Yildiz,Pedro Ruiz,Charles Nemeroff
Publisher : Oxford University Press
Release : 2015-05-22
ISBN : 0199300550
Language : En, Es, Fr & De

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Book Description :

As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Ayseg?l Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.

Mindfulness for Bipolar Disorder

Mindfulness for Bipolar Disorder Book
Author : William R. Marchand
Publisher : New Harbinger Publications
Release : 2015-05-01
ISBN : 1626251878
Language : En, Es, Fr & De

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Book Description :

In Mindfulness for Bipolar Disorder, psychiatrist and neuroscientist William R. Marchand provides an innovative,breakthrough program based in neuroscience and mindfulness practices to help you find relief from your bipolar symptoms. If you have bipolar disorder, you may experience feelings of mania or high energy, followed by periods of depression and sadness. These unusual shifts in mood, energy, and activity levels can make it extremely difficult to carry out day-to-day tasks—and ultimately reach your goals. Finding balance may be a daily struggle, even if you are on medication or in therapy. So, what else can you do to start feeling better? Mindfulness—the act of present moment awareness—may be the missing puzzle piece in effectively treating your bipolar disorder. In the book, you will learn how to actively work through feelings of depression, anxiety, and stress in order to improve the quality of your life. Written by a prominent psychiatrist, neuroscientist, and mindfulness teacher who draws upon his research experience and personal mindfulness practice as a monk in the Soto Zen tradition, this book will provide you with the tools needed to get your symptoms under control. If you’ve sought treatment for bipolar disorder but are still struggling with symptoms, mindfulness may be the missing piece to solving the bipolar puzzle and taking back your life. This book will help you get started right away.

Bipolar Disorder

Bipolar Disorder Book
Author : Stephen M. Strakowski,Melissa P. DelBello,Caleb M. Adler,David E. Fleck
Publisher : Oxford University Press
Release : 2020-01-22
ISBN : 0190908114
Language : En, Es, Fr & De

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Book Description :

Bipolar disorder is among the most common conditions affecting humankind and one of the leading causes of disability worldwide. It is a complex and dynamic psychiatric condition that makes it difficult to both understand and manage. However, with good management, people affected by bipolar disorder can lead very successful lives. This book was written specifically with new psychiatrists and mental health practitioners in mind to facilitate their ability to care for this condition. Chapters review clinical presentation and epidemiology, etiology and neurobiology, and treatment of bipolar disorder.

Bipolar Disorder in Youth

Bipolar Disorder in Youth Book
Author : Stephen M. Strakowski,Melissa P. DelBello,Caleb M. Adler
Publisher : Oxford University Press
Release : 2014-10-01
ISBN : 0199985375
Language : En, Es, Fr & De

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Book Description :

Bipolar disorders affect up to 3% of the world's population and are the 6th leading cause of disability worldwide. The estimated annual costs of bipolar disorder approach $50 billion in the United States, and the associated societal and personal suffering is immeasurable. Bipolar disorder is a lifelong illness that typically begins in mid-adolescence, thereby disrupting healthy developmental processes. It is also a progressive illness, making early intervention even more critical. As the disorder presents differently in youth as it does in adults, considerable controversy exists around the diagnosis in young people. The neurobiological factors leading to the onset of bipolar disorder reflect abnormalities in adolescent brain development. Bipolar disorder is strongly heritable and therefore, these developmental abnormalities likely represent the culmination of processes that precede the expression of symptoms. Current studies of children who are at risk for bipolar disorder are identifying these processes. Again, controversy exists about how to move these neuroscience gains forward to help affected individuals and, particularly to manage children at risk to delay or prevent the onset or progression of bipolar disorder. With these considerations in mind, Bipolar Disorder in Youth provides a timely, focused review of the diagnosis, treatment, and neurobiology of bipolar disorder in youth. It addresses current controversies and resolves those in which evidence is available. The book is organized into three sections based on these topics to provide comprehensive discussions to aid clinicians managing these individuals in their practices, as well as scientists trying to advance the field. The three editors are widely recognized experts in bipolar disorder, and the authors of each chapter represent international experts in the respective topics. Consequently, this book is the most comprehensive volume available discussing this important population and is a 'must' for the libraries of clinicians and scientists working with bipolar children and adolescents.

Clinical Manual for Management of Bipolar Disorder in Children and Adolescents

Clinical Manual for Management of Bipolar Disorder in Children and Adolescents Book
Author : Robert A. Kowatch,Mary A. Fristad,Robert L. Findling,Robert M. Post
Publisher : American Psychiatric Pub
Release : 2009-02-20
ISBN : 1585629022
Language : En, Es, Fr & De

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Book Description :

Clinical Manual for Management of Bipolar Disorder in Children and Adolescents was written in response to the growing body of knowledge surrounding pediatric bipolar illness and the underlying biological, environmental, and psychosocial influences that exacerbate symptoms and behavior. Written to provide clinically useful information about diagnosis and management, this manual is a comprehensive collection of empirical evidence, case studies, and the growing number of evidence-based reports on pediatric bipolar disorder over the past five years. This manual also contains several chapters provided by Dr. Mary Fristad and her team at The Ohio State University -- experts in family and psychosocial aspects of pediatric bipolar disorder. Her contributions, along with vast clinical evidence and the expertise provided by Drs. Kowatch, Findling, and Post, help paint an accurate picture of everything from age onset to the effectiveness of various therapies. In this manual, clinicians can refer to the following tools: A clinical description of childhood and adolescent bipolar disorder Management strategies for the patient including daily mood charting Current medication strategies and tactics Ways to help patients through the educational system Resources for clinicians, parents and patients A review of the future directions for childhood and adolescent bipolar disorder The many new developments in the field of pediatric bipolar disorder are affirming what this manual emphasizes -- that a combination of family and cognitive-behavior therapy can work in tandem with medical treatments to help young bipolar disorder patients achieve a more balanced life and a greater chance of controlling this illness later in life. The manual demonstrates how the medical community has shifted from asking, "Does bipolar disorder really exist in children and adolescents" to "How can we best predict, diagnose and treat this serious medical disorder" through a review of 25 years of study and insight.

Neuroprogression and Staging in Bipolar Disorder

Neuroprogression and Staging in Bipolar Disorder Book
Author : Flávio Kapczinski,Eduard Vieta,Pedro V. S. Magalhães,Michael Berk
Publisher : Oxford University Press, USA
Release : 2015
ISBN : 0198709994
Language : En, Es, Fr & De

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Book Description :

Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--

A Clinical Handbook on Child Development Paediatrics E Book

A Clinical Handbook on Child Development Paediatrics   E Book Book
Author : Sandra Johnson
Publisher : Elsevier Health Sciences
Release : 2012-10-31
ISBN : 072958089X
Language : En, Es, Fr & De

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Book Description :

This handbook offers a succinct study of Childhood Development Paediatrics with practical applications for helping the child and family through all areas of the developmental process. The book covers diverse topics like developmental delay, learning difficulties, attention deficit disorders, autism, Asperger syndrome, behaviour difficulties, language disorders, school refusal, bullying, emotional difficulties, neurological impairments that affect development (examples being cerebral palsy and brain injury) and motor coordination problems. It also offers online case scenarios on autism, ADHD, school refusal and truancy, cerebral palsy and child abuse and neglect. The cases are followed by questions to test the acquired knowledge of the student on these topics. This practical guide to child development is ideal for trainee paediatricians, registrars, paediatricians and general practitioners. Deals with developmental issues unlike comprehensive paediatric or child psychiatry texts Concise text providing practical tips Clinically and practically orientated (e.g. history, physical examination, assessment techniques) Comparison of normal and abnormal/normal development Definitions (Chapters.8,11,12) to clarify terms Several chapters (e.g. Chapters 8,9,10) inform about special problems/illnesses, which are increasing in incidence Online case scenarios on autism, ADHD, school refusal and truancy, cerebral palsy and child abuse and neglect are available on Student Consult. Combines physical and psychological problems in the development of children, which might be already present at birth (Cerebral Palsy) or which might be apparent later in life (Chapter 8)

Charney Nestler s Neurobiology of Mental Illness

Charney   Nestler s Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Pamela B. Sklar
Publisher : Oxford University Press
Release : 2018-01-12
ISBN : 019068142X
Language : En, Es, Fr & De

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Book Description :

Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.

Understanding Bipolar Disorder

Understanding Bipolar Disorder Book
Author : David J. Miklowitz,Dante Cicchetti
Publisher : Guilford Press
Release : 2010-05-04
ISBN : 1606236237
Language : En, Es, Fr & De

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Book Description :

This is the first book to systematically examine the development and course of bipolar disorder across the lifespan, identifying important directions for evidence-based treatment and prevention. The editors and contributors are foremost authorities who synthesize cutting-edge research at multiple levels of analysis, including genetic, neurobiological, cognitive, emotional, and family perspectives. Compelling topics include how bipolar symptoms change from childhood through adolescence and adulthood and the interplay of risk and protective factors at different developmental stages. The volume also addresses how developmental knowledge can inform the selection and timing of clinical interventions.

Bipolar Disorders New Insights for the Healthcare Professional 2013 Edition

Bipolar Disorders  New Insights for the Healthcare Professional  2013 Edition Book
Author : N.A
Publisher : ScholarlyEditions
Release : 2013-07-22
ISBN : 1481663488
Language : En, Es, Fr & De

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Book Description :

Bipolar Disorders: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Bipolar Disorders: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bipolar Disorders: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Psychiatry

Psychiatry Book
Author : Allan Tasman,Jerald Kay,Jeffrey A. Lieberman,Michael B. First,Michelle Riba
Publisher : John Wiley & Sons
Release : 2015-02-05
ISBN : 1118753364
Language : En, Es, Fr & De

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Book Description :

Now in a new Fourth Edition, Psychiatry remains the leading reference on all aspects of the current practice and latest developments in psychiatry. From an international team of recognised expert editors and contributors, Psychiatry provides a truly comprehensive overview of the entire field of psychiatry in 132 chapters across two volumes. It includes two new sections, on psychosomatic medicine and collaborative care, and on emergency psychiatry, and compares Diagnostic and Statistical Manual (DSM-5) and International Classification of Diseases (ICD10) classifications for every psychiatric disorder. Psychiatry, Fourth Edition is an essential reference for psychiatrists in clinical practice and clinical research, residents in training, and for all those involved in the treatment psychiatric disorders. Includes a a companion website at www.tasmanpsychiatry.com featuring PDFs of each chapter and downloadable images