Skip to main content

The Natural Anti Gal Antibody As Foe Turned Friend In Medicine

Download The Natural Anti Gal Antibody As Foe Turned Friend In Medicine Full eBooks in PDF, EPUB, and kindle. The Natural Anti Gal Antibody As Foe Turned Friend In Medicine is one my favorite book and give us some inspiration, very enjoy to read. you could read this book anywhere anytime directly from your device.

The Natural Anti Gal Antibody as Friend and Foe in Medicine

The Natural Anti Gal Antibody as Friend and Foe in Medicine Book
Author : Uri Galili
Publisher : Academic Press
Release : 2017-09-11
ISBN : 9780128133620
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the ?-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book. Provides tactics on how to improve cancer immunotherapy and viral vaccine immunogenicity Includes discussions on therapies that accelerate the healing of normal and chronic wounds, and of burns Covers the regeneration of bio-implants

The Natural Anti Gal Antibody as Foe Turned Friend in Medicine

The Natural Anti Gal Antibody as Foe Turned Friend in Medicine Book
Author : Uri Galili
Publisher : Academic Press
Release : 2017-09-05
ISBN : 0128133635
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book. Provides tactics on how to improve cancer immunotherapy and viral vaccine immunogenicity Includes discussions on therapies that accelerate the healing of normal and chronic wounds, and of burns Covers the regeneration of bio-implants

Sphingolipids in Cancer

Sphingolipids in Cancer Book
Author : Anonim
Publisher : Academic Press
Release : 2018-07-27
ISBN : 0128142243
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more. Provides information on cancer research, with this release focusing on sphingolipids Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Carbohydrate Antigens

Carbohydrate Antigens Book
Author : Per J. Garegg,Alf A. Lindberg,American Chemical Society. Division of Carbohydrate Chemistry
Publisher : Amer Chemical Society
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Covers recent developments in carbohydrate research in the chemical and biomedical arenas. Includes coverage of synthesis of artificial antigens and vaccines, structural determination of antigens, and molecular modelling of antigens interacting with antibodies and lectins. Also examines various biological, immunological and medical aspects. An opening chapter discusses the work of Dr. Michael Heidelberger. Valuable reading for carbohydrate, medicinal/pharmaceutical, and organic chemists and biochemists interested in biomedical research.

A Little History of the World

A Little History of the World Book
Author : E. H. Gombrich
Publisher : Yale University Press
Release : 2014-10-01
ISBN : 0300213972
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

E. H. Gombrich's Little History of the World, though written in 1935, has become one of the treasures of historical writing since its first publication in English in 2005. The Yale edition alone has now sold over half a million copies, and the book is available worldwide in almost thirty languages. Gombrich was of course the best-known art historian of his time, and his text suggests illustrations on every page. This illustrated edition of the Little History brings together the pellucid humanity of his narrative with the images that may well have been in his mind's eye as he wrote the book. The two hundred illustrations—most of them in full color—are not simple embellishments, though they are beautiful. They emerge from the text, enrich the author's intention, and deepen the pleasure of reading this remarkable work. For this edition the text is reset in a spacious format, flowing around illustrations that range from paintings to line drawings, emblems, motifs, and symbols. The book incorporates freshly drawn maps, a revised preface, and a new index. Blending high-grade design, fine paper, and classic binding, this is both a sumptuous gift book and an enhanced edition of a timeless account of human history.

Endotoxin Detection and Control in Pharma Limulus and Mammalian Systems

Endotoxin Detection and Control in Pharma  Limulus  and Mammalian Systems Book
Author : Kevin L. Williams
Publisher : Springer
Release : 2019-07-24
ISBN : 3030171485
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd “living fossil” (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma). Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of “at will” production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means of production and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated. Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease.

Nutrient Metabolism

Nutrient Metabolism Book
Author : Martin Kohlmeier
Publisher : Elsevier
Release : 2003-10-01
ISBN : 0080537898
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

Blood and Tissue Antigens

Blood and Tissue Antigens Book
Author : David Aminoff
Publisher : Academic Press
Release : 2014-06-28
ISBN : 1483282430
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Blood and Tissue Antigens documents the proceedings of the International Symposium on Blood and Tissue Antigens held in Ann Arbor, Michigan on September 17-19, 1969. This book focuses on the immunogenetic and biochemical aspects of the blood and tissue antigens. The topics discussed include the genetics of blood groups; blood groups and serum phosphatase; immunogenetics of the mouse H-2 system; and glycolipids as membrane antigens. The carbohydrate composition of epithelial mucins; glycolipids in SV40 and polyoma virus transformed mouse cell lines; and metabolic variations of serum proteins and enzymes are also elaborated. This text likewise covers the action of glycosidases on erythrocytes; blood group specific oligosaccharides in urine; biosynthesis of submaxillary mucins; and genes, glycosyltransferases, and blood types. This publication is a good source for students and individuals researching on blood and tissue antigens.

Fabry Disease

Fabry Disease Book
Author : Deborah Elstein,Gheona Altarescu,Michael Beck
Publisher : Springer Science & Business Media
Release : 2010-08-02
ISBN : 9048190339
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Fabry disease is an X-linked inborn error of metabolism wherein deficiency of a lysosomal enzyme results in systemic deposition of glycosphingolipids. Storage deposition, and hence pathological disease, occurs preferentially in renal glomerular and tubular epithelial cells, myocardial cells, heart valve fibrocytes, neurons of dorsal root ganglia, and in endothelial smooth muscle cells of blood vessels. Thus, Fabry disease is a multi-system disorder, albeit with considerable phenotypic heterogeneity in onset and in severity; however, it is progressive, exhibits extensive morbidity, and is life-threatening. Within the past two decades, there has been a radical change in the natural course Fabry disease by virtue of the availability of specific enzyme replacement therapy. Moreover, there has been a concerted effort to better understand the underlying pathology and equally to identify patients prior to the onset of irreversible end-organ damage. It is to be hoped that the future for patients with Fabry disease can be viewed with greater, albeit guarded, optimism. This state-of-the-art textbook attempts to bridge the span of pre-clinical studies, clinical finding, and management options in a readable but comprehensive manner for the medical practitioner as well as the interested non-medical reader.

Co signal Molecules in T Cell Activation

Co signal Molecules in T Cell Activation Book
Author : Miyuki Azuma,Hideo Yagita
Publisher : Springer Nature
Release : 2019-11-22
ISBN : 9813297174
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.

Reviews on Biomarker Studies in Aging and Anti Aging Research

Reviews on Biomarker Studies in Aging and Anti Aging Research Book
Author : Paul C. Guest
Publisher : Springer Nature
Release : 2019-09-06
ISBN : 3030256502
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as well as to clinical scientists, physicians and major drug companies. It provides important information on disease mechanisms, and each chapter is presented in the context of the aging process, specific chronic diseases or different therapeutic areas.

The Perfect Slime

The Perfect Slime Book
Author : Hans-Curt Flemming,Dr Thomas R. Neu,Dr Jost Wingender
Publisher : IWA Publishing
Release : 2016-09-15
ISBN : 1780407416
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Clostridia

Clostridia Book
Author : Hubert Bahl,Peter Dürre
Publisher : John Wiley & Sons
Release : 2001-10-15
ISBN : 9783527301751
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Clostridia have a high biotechnological potential, although they are generally still regarded more as a group of pathogenic microorganisms. They undertake a broad variety of biocatalytic reactions some of which are unique and of use in the chemical and biotechnology industry for the production of chemicals or for biopharmaceutical purposes. Even some of the clostridial toxins are of medical relevance and can be used as therapeutic agents; The book presents the biology, pyhsiology, and genetics, including genome projects of Clostridia and highlights their potential for industrial and medical applications. It is mostly based on research during the last decade which has brought significant progress in the field and outlines future perspectives of industrial interest.

T cells in Cancer

     T cells in Cancer Book
Author : Ilan Bank,Bruno Silva-Santos,Jurgen Kuball,Dieter Kabelitz,Seth Coffelt,Willi Born
Publisher : Frontiers Media SA
Release : 2021-02-22
ISBN : 2889663620
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). Dr. Dieter Kabelitz currently serves as the chairman for the IUIS Education Committee. Topic Editor Prof. Ilan Bank is Chief Scientific Officer of GammaCell Bio-Technologies Ltd. Topic Editor Prof. Jurgen Kuball is co-founder and scientific advisor of GADETA. Topic Editor Prof. Bruno Silva-Santos is co-founder of Lymphact S.A., a company now owned by GammaDelta Therapeutics. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Three to Get Married

Three to Get Married Book
Author : Fulton J. Sheen
Publisher : Scepter Publishers
Release : 2017-03-31
ISBN : 1594171203
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

One of the greatest and best-loved spokesmen for the Faith here sets out the Church's beautiful understanding of marriage in his trademark clear and entertaining style. Frankly and charitably, Sheen presents the causes of and solutions to common marital crises, and tells touching real-life stories of people whose lives were transformed through marriage. He emphasizes that our Blessed Lord is at the center of every successful and loving marriage. This is a perfect gift for engaged couples, or for married people as a fruitful occasion for self-examination.

Dietary Fiber

Dietary Fiber Book
Author : David Kritchevsky,Charles T. Bonfield,James W. Anderson
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461305195
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Twenty years ago the very idea of an international conference on the fiber contained in plant food would have been totally inconceivable. At that time fiber was generally viewed as an inert component of food of no nutritional value and consequently consid ered as a contaminant, the removal of which would enhance the purity of a product. It was measured by a now obsolete and almost worthless test introduced in the last century for veterinary rather than human nutrition, and what was measured was referred to as "crude fiber," containing part of the cellulose and lignin but none of the numerous components of fiber now known to play important roles in the maintenance of health. There were a few lone voices prior to the last two decades who had extolled the laxative properties of the undigested portion of food, assuming that these were related to its irritant action on the bowel mucosa. In retrospect this was a total misconception, and "softage" would have been a more appropriate term than "roughage," since its presence insured soft, not irritating, colon content.

The Age of Spiritual Machines

The Age of Spiritual Machines Book
Author : Ray Kurzweil
Publisher : Penguin
Release : 2000-01-01
ISBN : 1101077883
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Ray Kurzweil is the inventor of the most innovative and compelling technology of our era, an international authority on artificial intelligence, and one of our greatest living visionaries. Now he offers a framework for envisioning the twenty-first century--an age in which the marriage of human sensitivity and artificial intelligence fundamentally alters and improves the way we live. Kurzweil's prophetic blueprint for the future takes us through the advances that inexorably result in computers exceeding the memory capacity and computational ability of the human brain by the year 2020 (with human-level capabilities not far behind); in relationships with automated personalities who will be our teachers, companions, and lovers; and in information fed straight into our brains along direct neural pathways. Optimistic and challenging, thought-provoking and engaging, The Age of Spiritual Machines is the ultimate guide on our road into the next century.

Microbiome in Human Health and Disease

Microbiome in Human Health and Disease Book
Author : Pallaval Veera Bramhachari
Publisher : Springer Nature
Release : 2021-10-18
ISBN : 9811631565
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book
Author : Roger N. Rosenberg,Juan M. Pascual
Publisher : Elsevier
Release : 2014-10-28
ISBN : 0124105491
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Antioxidants in Therapy and Preventive Medicine

Antioxidants in Therapy and Preventive Medicine Book
Author : Ingrid Emerit,Lester Packer,Christian Auclair
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1468457306
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Twenty years ago, the enzyme superoxide dismutase which uses the superoxide radical anion as its specific substrate was reported. With this discovery was born a new scientific field, in which oxygen, necessary for aerobi c 1 ife on thi s planet, had to be cons i dered also in terms of its toxicity and stresses. This stimulated the search for knowledge of active oxygen species in biology and medicine. Superoxide and other reactive oxygen species are now implicated in many disease processes. Major advances have been achieved during these past years with respect to free radical generation and mechanisms of free radical action in causing tissue injury. In parallel, the possibil ity of influencing free radical related disease processes by antioxidant treatment was studied in various in vitro and in vivo systems. This was the unique theme of a conference organized in Paris by the Society for Free Radical Research (December 9-10, 1988) which brought together experts from basic sciences and clinicians in order to evaluate the current status of antioxidant therapy. The conference emphasized fundamental processes in antioxidant action. Among the major topics were superoxide dismutase (SOD) and low molecular weight substances with such activity, called SOD mimics. Other antioxidant enzymes were also considered. Antioxidant vitamins, in particular vitamins E and C, other naturally occurri ng antioxidants and vari ous synthet i c antioxidants were included in the presentations as there is now a rapidly developing series of compounds with potentially interesting clinical applications.