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The Molecular Basis Of Cancer

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The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson
Publisher : Saunders
Release : 2014-02-19
ISBN : 9781455740666
Language : En, Es, Fr & De

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Book Description :

The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. Access the entire text and illustrations online, fully searchable, at Expert Consult.

The Molecular Basis of Cancer E Book

The Molecular Basis of Cancer E Book Book
Author : John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson
Publisher : Elsevier Health Sciences
Release : 2014-01-04
ISBN : 0323261965
Language : En, Es, Fr & De

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Book Description :

Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology.

The Molecular Basis of Human Cancer

The Molecular Basis of Human Cancer Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Springer Science & Business Media
Release : 2001-08-10
ISBN : 1592591256
Language : En, Es, Fr & De

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Book Description :

Internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, and skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms in cancer induction.

The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson
Publisher : Elsevier Health Sciences
Release : 2008-04-01
ISBN : 1437710999
Language : En, Es, Fr & De

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Book Description :

Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.

The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : John Mendelsohn,Peter M. Howley,Mark A. Israel,Lance A. Liotta,Joe W. Gray,Craig B. Thompson
Publisher : W B Saunders Company
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The state-of-the-art 2nd Edition of this acclaimed reference explains the principles that form the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. Readers will find a broad update on the scientific principles of new diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating the latest advances and newest research, this text also gives thorough descriptions of everything from the basic mechanisms of malignant cells and molecular abnormalities in common cancers to new approaches for cancer therapy. Each chapter discusses the clinical implications for treatment. Numerous examples of the latest clinical interventions help readers understand and assess the products of the biotechnology revolution. IMPORTANT new topics, including chemo-prevention, programmed cell death (apoptosis), genetic counselling, tumour-specific vaccines, genetic abnormalities in the origin and progression of cancer, monoclonal antibody therapy, and molecular predictors of prognosis and response to treatment NEW and revised chapters, covering new basic science knowledge, new approaches to treatment and keeping all information on the cutting-edge of the specialty ABUNDANT illustrations, most of them new, to clarify and explain difficult concepts.

The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : Peter B. Farmer,John M. Walker
Publisher : Springer
Release : 2012-04-03
ISBN : 9781468473155
Language : En, Es, Fr & De

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Book Description :

This book aims to describe the current state of knowledge and possible future developments in a number of major areas of research into the nature, causes and treatment of cancer. The contributing authors have been encouraged to discuss their subjects at the molecular level. It will become apparent to the reader that considerable developments in the understanding of the fundamental nature of cancer, in molecular terms, are constantly being made. This is particularly the case in the area of oncogene research where differences between tumour and normal cells can now be defined in terms of altered expression of DNA sequences. An understanding of the methods available for detecting cancer, of the process of carcinogenesis and of the means available for treating cancer can only be achieved with a precise knowledge of the basic biochemical and molecular processes involved. Since it is all to easy for the research scientist to become totally absorbed within the specialised area of research in which he is involved, the first chapter is an attempt to encourage a broader field of vision by introducing the clinician's view of the cancer problem, which illustrates the broad spectrum of basic problems that need to be solved by the cancer researcher.

Molecular Basis of Cancer Macromolecular structure carcinogens and oncogenes

Molecular Basis of Cancer  Macromolecular structure  carcinogens  and oncogenes Book
Author : Robert Rein
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Molecular Basis of Cancer Macromolecular structure carcinogens and oncogenes book written by Robert Rein, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : John Mendelsohn
Publisher : Saunders
Release : 1995
ISBN : 9780721664835
Language : En, Es, Fr & De

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Book Description :

This comprehensive, new reference will provide clinicians and other professionals who manage cancer patients, the scientific tools necessary to fully understand the disease and its therapy. The sequence of chapters leads the reader from the basic mechanisms of malignant transformation of cells, to the molecular and biological features of tumour growth and metastasis in the body, then to the molecular abnormalities found in common types of cancer, and finally to the molecular basis for new approaches to cancer therapy. The text reveals the very latest scientific research in cancer treatment and supplies the foundation for new approaches to evaluation and therapy of cancer patients.

Molecular Basis of Human Cancer

Molecular Basis of Human Cancer Book
Author : C. Nicolini
Publisher : Springer Science & Business Media
Release : 2013-11-21
ISBN : 1489925635
Language : En, Es, Fr & De

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Book Description :

During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the Italian Ministry of Universities and of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and Technobiochip. The subject of the course was "Molecular Basis of Human Cancer" with participants selected worldwide from 15 different countries. The purpose of the course was to address, in a tutorial and structural fashion, the molecular basis of human cancer, including the mechanism of signal transduction in mammalian cells, the genetic mechanism of malignant transformation in man, growth factors, hormone receptors, cell membrane and cytoskeleton, and DNA high order structure. The course had this as its major objective and the resulting book reflects it. The participants were exposed to a critical evaluation of current knowledge about cancer and to some of the key problems that remain as stumbling blocks to our eventual understanding of this important biological and medical problem. Through the media of formal and informal lectures, workshops, symposia and informal discussions, a select group of interested young and senior scientists were acquainted with many of the aspects of human cancer.

The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : Peter B. Farmer,John M. Walker
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1468473131
Language : En, Es, Fr & De

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Book Description :

This book aims to describe the current state of knowledge and possible future developments in a number of major areas of research into the nature, causes and treatment of cancer. The contributing authors have been encouraged to discuss their subjects at the molecular level. It will become apparent to the reader that considerable developments in the understanding of the fundamental nature of cancer, in molecular terms, are constantly being made. This is particularly the case in the area of oncogene research where differences between tumour and normal cells can now be defined in terms of altered expression of DNA sequences. An understanding of the methods available for detecting cancer, of the process of carcinogenesis and of the means available for treating cancer can only be achieved with a precise knowledge of the basic biochemical and molecular processes involved. Since it is all to easy for the research scientist to become totally absorbed within the specialised area of research in which he is involved, the first chapter is an attempt to encourage a broader field of vision by introducing the clinician's view of the cancer problem, which illustrates the broad spectrum of basic problems that need to be solved by the cancer researcher.

The Biological Basis of Cancer

The Biological Basis of Cancer Book
Author : Robert G. McKinnell
Publisher : Cambridge University Press
Release : 2006-08-28
ISBN : 0521844584
Language : En, Es, Fr & De

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Book Description :

This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.

The Molecular Basis of Cancer

The Molecular Basis of Cancer Book
Author : PB. Farmer
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Molecular Basis of Cancer book written by PB. Farmer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Basis of Breast Cancer

Molecular Basis of Breast Cancer Book
Author : Jose Russo,Irma H. Russo
Publisher : Springer Science & Business Media
Release : 2004
ISBN : 9783540003915
Language : En, Es, Fr & De

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Book Description :

This richly illustrated atlas-like book provides a foundation for the biological and molecular understanding of how the mammary gland develops and how breast cancer originates. The main goal is to comprehensively review in ten chapters fundamental knowledge in breast cancer. New paradigms are described in which induction of differentiation in the mammary gland can promote prevention and cure of breast cancer. The book is extremely helpful both for clinicians treating patients and researchers looking for new avenues of development.

Molecular Basis of Cancer Suppression by the Retinoblastoma and P53 Genes

Molecular Basis of Cancer Suppression by the Retinoblastoma and P53 Genes Book
Author : Phang-Lang Chen
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Molecular Basis of Cancer Suppression by the Retinoblastoma and P53 Genes book written by Phang-Lang Chen, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Signaling Networks and Cell Cycle Control

Signaling Networks and Cell Cycle Control Book
Author : J. Silvio Gutkind
Publisher : Springer Science & Business Media
Release : 2000-04-14
ISBN : 159259218X
Language : En, Es, Fr & De

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Book Description :

Leading scientists summarize the latest findings on signal transduction and cell cycle regulation and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their ligands, and their downstream pathways. Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules. Cutting-edge and highly suggestive, Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases presents a wealth of information on the emerging principles of the field, as well as an invaluable guide for all experimental and clinical investigators of cell regulation and its rapidly emerging pharmacological opportunities today.

Molecular Pathology

Molecular Pathology Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Release : 2009-03-10
ISBN : 9780123859129
Language : En, Es, Fr & De

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Book Description :

Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam Master® web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site – will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of “molecular medicine and the translational aspects of molecular pathology

The Enemy Within

The Enemy Within Book
Author : Wellcome Trust
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Enemy Within book written by Wellcome Trust, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Human Molecular Biology

Human Molecular Biology Book
Author : R. J. Epstein
Publisher : Cambridge University Press
Release : 2003
ISBN : 9780521644815
Language : En, Es, Fr & De

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Book Description :

An introduction to the molecular basis of health and disease for the new generation of students.

The Molecular Basis of Neoplasia

The Molecular Basis of Neoplasia Book
Author : M.D. Anderson Hospital and Tumor Institute
Publisher : Unknown
Release : 1962
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Molecular Basis of Neoplasia book written by M.D. Anderson Hospital and Tumor Institute, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Molecular Basis of Human Cancer

The Molecular Basis of Human Cancer Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Humana Press
Release : 2016-11-11
ISBN : 1597454583
Language : En, Es, Fr & De

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Book Description :

This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.