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The Heart In Systemic Autoimmune Diseases

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The Heart in Rheumatic Autoimmune and Inflammatory Diseases

The Heart in Rheumatic  Autoimmune and Inflammatory Diseases Book
Author : Udi Nussinovitch
Publisher : Academic Press
Release : 2017-02-10
ISBN : 0128032685
Language : En, Es, Fr & De

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Book Description :

The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

The Heart in Systemic Autoimmune Diseases

The Heart in Systemic Autoimmune Diseases Book
Author : Andrea Dorea
Publisher : Elsevier
Release : 2004-01-20
ISBN : 0080507964
Language : En, Es, Fr & De

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Book Description :

This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined. This book yields an impressive body of well ordered information, highlighting key references and summarising the experience of a selected panel of distinguished physician-scientists actively involved in the field of cardiovascular disease and systemic autoimmunity.

The Saint Chopra Guide to Inpatient Medicine

The Saint Chopra Guide to Inpatient Medicine Book
Author : Sanjay Saint,Vineet Chopra
Publisher : Oxford University Press
Release : 2018-11-09
ISBN : 0190862823
Language : En, Es, Fr & De

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Book Description :

THE DEFINITIVE GUIDE TO INPATIENT MEDICINE, UPDATED AND EXPANDED FOR A NEW GENERATION OF STUDENTS AND PRACTITIONERS A long-awaited update to the acclaimed Saint-Frances Guides, the Saint-Chopra Guide to Inpatient Medicine is the definitive practical manual for learning and practicing inpatient medicine. Its end-to-end coverage of the specialty focuses on both commonly encountered problems and best practices for navigating them, all in a portable and user-friendly format. Composed of lists, flowcharts, and "hot key" clinical insights based on the authors' decades of experience, the Saint-Chopra Guide ushers clinicians through common clinical scenarios from admission to differential diagnosis and clinical plan. It will be an invaluable addition -- and safety net -- to the repertoire of trainees, clinicians, and practicing hospitalists at any stage of their career.

The Heart in Systemic Autoimmune Diseases

The Heart in Systemic Autoimmune Diseases Book
Author : Fabiola Atzeni,Andrea Dorea,Mike Nurmohamed,Paolo Pauletto
Publisher : Elsevier
Release : 2017-02-11
ISBN : 0444636692
Language : En, Es, Fr & De

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Book Description :

The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics. Presents an impressive body of well ordered information on the topic of cardiovascular diseases and their relationship to autoimmune illness Highlights key references Summarizes the experience of a selected panel of distinguished physician-scientists who are actively involved in the field of cardiovascular disease and systemic autoimmunity

Lahita s Systemic Lupus Erythematosus

Lahita s Systemic Lupus Erythematosus Book
Author : Robert G. Lahita
Publisher : Academic Press
Release : 2021-07-23
ISBN : 0323914888
Language : En, Es, Fr & De

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Book Description :

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries. Completely updated, revised, and expanded with the most comprehensive and accessible reference on SLE for clinicians and scientists Full-color presentation throughout the book Provides the latest information available on diagnosis and treatment Incorporates an international panel of authors who are experts in their fields, with an emphasis on young, cutting-edge scientists and physicians

Atherosclerosis and Autoimmunity

Atherosclerosis and Autoimmunity Book
Author : Yehuda Shoenfeld,D. Harats,G. Wick
Publisher : Elsevier
Release : 2001-02-27
ISBN : 9780080527659
Language : En, Es, Fr & De

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Book Description :

Presenting further studies in the prevention and treatment of coronary artery disease, this book brings together the knowledge accrued in the past decade concerning the role of immunity in the initiation and perpetuation of atherosclerosis. A strong group of international contributors summarize the diverse aspects of the interrelationship between the immune system and atherosclerosis.

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases Book
Author : Ricard Cervera,Gerard Espinosa,Munther Khamashta
Publisher : Elsevier
Release : 2016-06-18
ISBN : 0444636560
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics. Brings the reader up-to-date and allows easy access to individual topics in one place Written by a respected panel of distinguished physicians/scientists actively involved in the field of Antiphospholipid Syndrome Includes box summaries at the end of each chapter that highlight important topics Gives up-to-date, basic knowledge and a modern approach to diagnosis and therapy Provides a comprehensive review of this major disease Includes information on treatment options available

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases Book
Author : Michael Lockshin,D. Ware Branch
Publisher : Gulf Professional Publishing
Release : 2006
ISBN : 0444518010
Language : En, Es, Fr & De

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Book Description :

This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy. * Authors share an academic interest in the unique relationship between being a woman and having an autoimmune disease * Touches on controversial topics, such as the mechanism of antiphospholipid-related fetal loss and whether or not non-steroidal anti-inflammatory agents should be used in pregnancy * Includes critical and balanced reviews of the controversial association between autoimmune disease and female infertility

Immunopathogenesis and Immune based Therapy for Selected Autoimmune Disorders

Immunopathogenesis and Immune based Therapy for Selected Autoimmune Disorders Book
Author : Mourad Aribi
Publisher : BoD – Books on Demand
Release : 2017-03-22
ISBN : 9535130218
Language : En, Es, Fr & De

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Book Description :

The book Immunopathogenesis and Immune-Based Therapy for Selected Autoimmune Disorders is a synthesis work that discusses two main aspects of autoimmunity: Immunopathogenesis and therapeutic approaches essentially based on the immunotherapies. This book deals with different topics on a number of autoimmune disorders, including type 1 diabetes, autoimmune cardiomyopathy, autoimmunity of gastrointestinal tract, systemic sclerosis, and myasthenia gravis. This book will be useful to clinicians, biologists, researchers, teachers, and students who are interested in immunology and immunopathology.

The Immunology of Cardiovascular Homeostasis and Pathology

The Immunology of Cardiovascular Homeostasis and Pathology Book
Author : Susanne Sattler,Teresa Kennedy-Lydon
Publisher : Springer
Release : 2017-06-30
ISBN : 3319576135
Language : En, Es, Fr & De

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Book Description :

Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.

Janeway s Immunobiology

Janeway s Immunobiology Book
Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Release : 2010-06-22
ISBN : 9780815344575
Language : En, Es, Fr & De

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Book Description :

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases Book
Author : Michael Lockshin,Ware Branch
Publisher : Elsevier
Release : 2005-12-07
ISBN : 008046095X
Language : En, Es, Fr & De

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Book Description :

This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy. * Authors share an academic interest in the unique relationship between being a woman and having an autoimmune disease * Touches on controversial topics, such as the mechanism of antiphospholipid-related fetal loss and whether or not non-steroidal anti-inflammatory agents should be used in pregnancy * Includes critical and balanced reviews of the controversial association between autoimmune disease and female infertility

Right Heart Pathology

Right Heart Pathology Book
Author : Silviu Ionel Dumitrescu,Ion C. Ţintoiu,Malcolm John Underwood
Publisher : Springer
Release : 2018-05-31
ISBN : 3319737643
Language : En, Es, Fr & De

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Book Description :

This book reviews the management of right heart diseases, incorporating etiology, physiopathology, prevention, diagnosis and treatment. The frequency of this pathology has increased in recent years, while techniques for its treatment have evolved. This book therefore represents a complete, detailed and updated presentation of this pathology, reviewing the expanded treatment options while considering the management of patients in detail. Right Heart Pathology: From Mechanism to Management provides a comprehensive insight into right heart pathology, current diagnostic methods, treatments and postsurgical management. Written by experienced cardiologists and cardiovascular surgeons who have addressed significant issues in this topic area, it represents the essential reference in this specialty.

The Lung in Autoimmune Diseases

The Lung in Autoimmune Diseases Book
Author : Fabiola Atzeni,Jose Gomez-Puerta,Jacobo Sellares
Publisher : Elsevier
Release : 2022-02-16
ISBN : 032391084X
Language : En, Es, Fr & De

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Book Description :

The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung’s functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases. Provides a comprehensive review of the different patterns of pulmonary involvement in systemic autoimmune diseases Describes new, targeted therapies for the treatment of systemic autoimmune diseases, including anti-fibrotics, biologics and vasodilators Gives insights on the prognosis of patients suffering from systemic autoimmune diseases Depicts better definitions of types of lung involvement in patients with an underlying systemic autoimmune disease

Progress in Systemic Lupus Erythematosus Research

Progress in Systemic Lupus Erythematosus Research Book
Author : Tomas I. Seward
Publisher : Nova Publishers
Release : 2007
ISBN : 9781600218613
Language : En, Es, Fr & De

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Book Description :

This new book is devoted to leading-edge research developments in lupus which is a condition of chronic inflammation caused by an autoimmune disease. Autoimmune diseases are illnesses that occur when the body's tissues are attacked by its own immune system. The immune system is a complex system within the body that is designed to fight infectious agents, for example, bacteria, and other foreign invaders. One of the mechanisms that the immune system uses to fight infections is the production of antibodies. Patients with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. Because the antibodies and accompanying cells of inflammation can involve tissues anywhere in the body, lupus has the potential to affect a variety of areas of the body. Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).

Autoimmune Diseases

Autoimmune Diseases Book
Author : Munther A Khamashta,Manuel Ramos-Casals
Publisher : Springer Science & Business Media
Release : 2011-05-26
ISBN : 0857293583
Language : En, Es, Fr & De

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Book Description :

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Surgery in Rheumatic and Musculoskeletal Disease

Surgery in Rheumatic and Musculoskeletal Disease Book
Author : Fabiola Atzeni,Ignacio Francesco Masala,Daniel Aletaha,Marcus Lee,Xenofon Baraliakos
Publisher : Elsevier
Release : 2018-03-26
ISBN : 0444638881
Language : En, Es, Fr & De

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Book Description :

Surgery in Systemic Autoimmune Disease, Volume 15, describes the state-of-the-art of the use of surgery in treating the most common systemic autoimmune diseases (SADS). The volume consists of an introductory chapter concerning the impact of surgery on SADs, follow by eight chapters describing the use of surgery in the treatment of specific diseases in various areas (cardiology, gastroenterology, orthopedics, neurology. etc.) and the possible difficulties and complications. The final five chapters deal with the possible complications arising during the course of biological and non-biological treatment, also providing recommendation concerning their management. International in scope, the list of more than 20 contributors from Europa and America reads like a who’s who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on surgical problems in SADs Provides a practical guide to the safer use of surgery in patients with autoimmune diseases Includes a number of problems and recommendations that cannot be found in other books Designed as a ‘guide to clinical practice’ for surgical interventions required by patients with SADs Gives a comprehensive review of the available surgical options

Pathogenesis of Systemic Lupus Erythematosus

Pathogenesis of Systemic Lupus Erythematosus Book
Author : Alberta Hoi
Publisher : Springer Nature
Release : 2022-08-14
ISBN : 3030851613
Language : En, Es, Fr & De

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Book Description :

Download Pathogenesis of Systemic Lupus Erythematosus book written by Alberta Hoi, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

MGH Cardiology Board Review

MGH Cardiology Board Review Book
Author : Hanna K. Gaggin,James L. Januzzi Jr.
Publisher : Springer Nature
Release : 2020-11-11
ISBN : 3030457923
Language : En, Es, Fr & De

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Book Description :

This comprehensively revised new edition prepares the reader for the cardiology board examination, as well as provide a concise review of the essentials of general cardiology and the less common but clinically relevant topics in a dynamic and time-efficient manner, augmenting existing learning. It uses board-style questions and answers at the end of each topic, enabling readers to test their learning and commit key concepts to long-term memory. Instructive figures and tables are used to consolidate teaching points. This book also contains practical tips from recent board exam takers and other resources in order to make best use of the reader’s limited time. In the MGH Cardiology Board Review, the Editors have compiled the expertise of over 60 experienced authors in a succinct volume, applying methods thoroughly tested in Board Review. In addition, two very important sections on ECGs and images are included, contents of which are derived from the board examination answer keys, the very ones that readers are expected to know. Plans on how to best approach board examination preparation and what additional resources to go to are provided. In short, this book has all the strengths to ensure your success on the boards exam.

Dubois Lupus Erythematosus and Related Syndromes E Book

Dubois  Lupus Erythematosus and Related Syndromes   E Book Book
Author : Daniel Wallace,Bevra Hannahs Hahn
Publisher : Elsevier Health Sciences
Release : 2018-08-16
ISBN : 0323550649
Language : En, Es, Fr & De

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Book Description :

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes. Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients. Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS). Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment. Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.