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The Heart In Rheumatic Autoimmune And Inflammatory Diseases

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The Heart in Rheumatic Autoimmune and Inflammatory Diseases

The Heart in Rheumatic  Autoimmune and Inflammatory Diseases Book
Author : Udi Nussinovitch
Publisher : Academic Press
Release : 2017-01-13
ISBN : 9780128032671
Language : En, Es, Fr & De

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Book Description :

The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and forty distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date "level of evidence" and "strengths of recommendations" for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

The Heart in Rheumatic Autoimmune and Inflammatory Diseases

The Heart in Rheumatic  Autoimmune and Inflammatory Diseases Book
Author : Udi Nussinovitch
Publisher : Academic Press
Release : 2017-02-10
ISBN : 0128032685
Language : En, Es, Fr & De

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Book Description :

The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

The Heart in Systemic Autoimmune Diseases

The Heart in Systemic Autoimmune Diseases Book
Author : Fabiola Atzeni,Andrea Dorea,Mike Nurmohamed,Paolo Pauletto
Publisher : Elsevier
Release : 2017-02-11
ISBN : 0444636692
Language : En, Es, Fr & De

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Book Description :

The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics. Presents an impressive body of well ordered information on the topic of cardiovascular diseases and their relationship to autoimmune illness Highlights key references Summarizes the experience of a selected panel of distinguished physician-scientists who are actively involved in the field of cardiovascular disease and systemic autoimmunity

The Heart in Systemic Autoimmune Diseases

The Heart in Systemic Autoimmune Diseases Book
Author : Andrea Dorea
Publisher : Elsevier
Release : 2004-01-20
ISBN : 9780080507965
Language : En, Es, Fr & De

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Book Description :

This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined. This book yields an impressive body of well ordered information, highlighting key references and summarising the experience of a selected panel of distinguished physician-scientists actively involved in the field of cardiovascular disease and systemic autoimmunity.

Emerging Technologies for Heart Diseases

Emerging Technologies for Heart Diseases Book
Author : Udi Ehud Nussinovitch
Publisher : Academic Press
Release : 2020-03
ISBN : 9780128137062
Language : En, Es, Fr & De

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Book Description :

The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options. Provides a comprehensive review of the latest therapeutic developments for heart failure, valvular disorders, myocardial ischemia and arrhythmias, and their clinical implications. Written by both specialists in the field and established researchers, it delivers a review of emerging medical technologies and presents insight into their therapeutic promise. Chapters are arranged according to disease pathogeneses and relevance and include coverage of the mechanical, electrophysiological, and biological approaches for the management of patients with heart failure should be replaced with heart failure and valvular disorders.

Emerging Technologies for Heart Diseases

Emerging Technologies for Heart Diseases Book
Author : Udi Ehud Nussinovitch
Publisher : Academic Press
Release : 2020-03
ISBN : 9780128137048
Language : En, Es, Fr & De

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Book Description :

The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options. Provides a comprehensive review of the latest therapeutic developments for heart failure, valvular disorders, myocardial ischemia and arrhythmias, and their clinical implications. Written by both specialists in the field and established researchers, it delivers a review of emerging medical technologies and presents insight into their therapeutic promise. Chapters are arranged according to disease pathogeneses and relevance and include coverage of the mechanical, electrophysiological, and biological approaches for the management of patients with myocardial ischemia and arrhythmias.

The Pure Cure for Arthritis and Other Auto Immune and Inflammatory Diseases

The Pure Cure for Arthritis and Other Auto Immune and Inflammatory Diseases Book
Author : Bob L. Owen,Thomas Johnson
Publisher : Unknown
Release : 1997-08
ISBN : 9781882657148
Language : En, Es, Fr & De

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Book Description :

Download The Pure Cure for Arthritis and Other Auto Immune and Inflammatory Diseases book written by Bob L. Owen,Thomas Johnson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases

Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases Book
Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Release : 2012
ISBN : 012397156X
Language : En, Es, Fr & De

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Book Description :

Antioxidant flavonoids for arthritis treatment : Human and animal models / S.G. Somasundaram, B. Oommen -- Inflammation in arthritis / N.J. Correa-Matos, S.B. Vaghefi -- Effects of beef on inflammation affecting arthritis / A.E. Galena -- Contribution of bioactive foods and their emerging role in immunomodulation, inflammation, and arthritis / N. Khan ... [et al.] -- Curcumin and joint health : From traditional knowledge to clinical validation / S. Togni, G. Appendino -- Dried plum and bone health / B.J. Smith, E. Rendina, E.A. Lucas -- The alkaline way : Integrative management of rheumatoid arthritisand other autoimmune conditions / R. Jaffe -- Marine omega-3 polyunsaturated fatty acids and rheumatoid arthritis / P.C. Calder -- Diet modulated inflammation in chronic disease : An overview / G. Egger -- Food supplements and immune function in humans / J. Romeo ... [et al.] -- Natural antioxidants and resistance to infection / M.A. Puertollano ... [et al.] -- The effects of flavonoids on ...

Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases

Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases Book
Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Release : 2019-01-26
ISBN : 0128138211
Language : En, Es, Fr & De

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Book Description :

Bioactive Food as Dietary Interventions for Arthritis and Inflammatory Diseases, Second Edition is a valuable scientific resource that focuses on the latest advances in bioactive food research and the potential benefit of bioactive food choice on arthritis. Written by experts from around the world, the book presents important information that can help improve the health of those at risk for arthritis and related conditions using food selection as its foundation. Serves as a starting point for in-depth discussions in academic settings Offers detailed, well-documented reviews outlining the ability of bioactive foods to improve and treat arthritis Includes updated research on the global epidemic of diabetes Updated with current research on antioxidant flavonoids, anti-Inflammatory natural foods, ginger and the effects of beef on inflammation Documents foods that can affect metabolic syndrome and ways the associated information could be used to understand other diseases that share common etiological pathways

Inflammation Protocols

Inflammation Protocols Book
Author : Paul Winyard,Derek A. Willoughby
Publisher : Humana Press
Release : 2010-10-28
ISBN : 9781617372827
Language : En, Es, Fr & De

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Book Description :

Inflammation has been described as the basis of many pathologies of human disease. When one considers the updated signs of inflammation, they would be vasodilation, cell migration, and, in the case of chronic inflam- tion, cell proliferation, often with an underlying autoimmune basis. Gen- ally, inflammation may be divided into acute, chronic, and autoimmune, - though the editors believe that most, if not all, chronic states are often the result of an autoimmune response to an endogenous antigen. Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well. The lack of advances in classical inflammatory diseases, such as rh- matoid arthritis, may in part arise from a failure to classify the disease into different forms. That different forms exist is exemplified in patients with d- fering responses to existing antiinflammatory drugs, ranging from nonresponders to very positive responders for a particular nonsteroidal an- inflammatory drug (NSAID). Though researchers have progressively unr- eled the mechanisms, the story is far from complete. It should also be noted that the inflammatory response is part of the innate immune response, or to use John Hunter’s words in 1795, “inflammation is a salutary response.” That may be applied in particular to the defensive response to invading micro- ganisms.

Autoimmune Diseases and Diagnostic Approaches

Autoimmune Diseases and Diagnostic Approaches Book
Author : Kenan Demir,Selim Görgün
Publisher : Cambridge Scholars Publishing
Release : 2021-06-17
ISBN : 152757119X
Language : En, Es, Fr & De

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Book Description :

The collection of essays reviews, explores, and reports state-of-the-art autoimmune diseases and their diagnostics. It provides a comprehensive presentation of autoimmune diseases, diagnostic approaches with current trends, and possible developments in health sciences. As such, it is a unique resource for medical educators, medical practitioners, and academics.

Dubois Lupus Erythematosus and Related Syndromes E Book

Dubois  Lupus Erythematosus and Related Syndromes   E Book Book
Author : Daniel Wallace,Bevra Hannahs Hahn
Publisher : Elsevier Health Sciences
Release : 2018-08-16
ISBN : 0323550649
Language : En, Es, Fr & De

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Book Description :

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes. Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients. Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS). Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment. Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.

The Biology of Extracellular Molecular Chaperones

The Biology of Extracellular Molecular Chaperones Book
Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Release : 2008-04-30
ISBN : 9780470754023
Language : En, Es, Fr & De

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Book Description :

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified as the presence of unfolded proteins within the cell. It is now known that this is a key mechanism enabling cells to survive a multitude of physical, chemical and biological stresses. Since the promulgation of the ‘molecular chaperone’ concept as a general cellular function to control the process of correct protein folding, a large number of molecular chaperones and protein folding catalysts have been identified, and it has been recognized that not all molecular chaperones are stress proteins and vice versa. The discovery of molecular chaperones as folding proteins went hand-in-hand with their recognition as potent immunogens in microbial infection. It was subsequently shown that administration of molecular chaperones such as Hsp60, Hsp70 or Hsp90 could inhibit experimental autoimmune diseases and cancer. More recently evidence has accumulated to show that certain molecular chaperones are also present on the surface of cells or in extracellular fluids. A new paradigm is emerging: at least some molecular chaperones are secreted proteins with pro- or anti-inflammatory actions, regulating the immune response in human diseases such as coronary heart disease, diabetes and rheumatoid arthritis. In addition to having direct effects on cells, molecular chaperones can bind peptides and present them to T cells to modulate immune responses. This may be significant in the treatment of cancer. This is the first book bringing leading researchers in this field together to review and discuss: our current knowledge of cell stress response and molecular chaperones the changing paradigms of protein trafficking and function cell stress proteins as immunomodulators and pro- and anti-inflammatory signalling molecules the role of these proteins in various chronic diseases and their potential as preventative or therapeutic agents. The Biology of Extracellular Molecular Chaperones is of particular interest to immunologists, cell and molecular biologists, microbiologists and virologists, as well as clinical researchers working in cardiology, diabetes, rheumatoid arthritis and other inflammatory diseases.

Inflammation Protocols

Inflammation Protocols Book
Author : Paul G. Winyard,Derek A. Willoughby
Publisher : Humana
Release : 2003-04-08
ISBN : 9780896039704
Language : En, Es, Fr & De

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Book Description :

Inflammation has been described as the basis of many pathologies of human disease. When one considers the updated signs of inflammation, they would be vasodilation, cell migration, and, in the case of chronic inflam- tion, cell proliferation, often with an underlying autoimmune basis. Gen- ally, inflammation may be divided into acute, chronic, and autoimmune, - though the editors believe that most, if not all, chronic states are often the result of an autoimmune response to an endogenous antigen. Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well. The lack of advances in classical inflammatory diseases, such as rh- matoid arthritis, may in part arise from a failure to classify the disease into different forms. That different forms exist is exemplified in patients with d- fering responses to existing antiinflammatory drugs, ranging from nonresponders to very positive responders for a particular nonsteroidal an- inflammatory drug (NSAID). Though researchers have progressively unr- eled the mechanisms, the story is far from complete. It should also be noted that the inflammatory response is part of the innate immune response, or to use John Hunter’s words in 1795, “inflammation is a salutary response.” That may be applied in particular to the defensive response to invading micro- ganisms.

The People Power Health Superbook Book 10 Immune System Diseases

The    People Power    Health Superbook  Book 10  Immune System Diseases Book
Author : Tony Kelbrat
Publisher : Lulu Press, Inc
Release : 2014-04-04
ISBN : 1312070943
Language : En, Es, Fr & De

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Book Description :

Very simply, all the cells in the bodily organism have a special marker in them which the immune system knows are its own but everything else in the body without this special marker is considered a foreign agent, an enemy which the immune system tries to destroy in order to win this war against toxins and continue to thrive. When the immune system senses large amounts of foreign invaders, it triggers an immune response by producing antibodies which go out, fight these invaders (antigens) and try to destroy them all. When the body’s immune system is weak, it gets confused and sometimes attacks its own healthy body cells because it thinks these cells are foreign invading toxic cells so the body’s immune system is destroying itself. There are a lot of diseases like this like chronic inflammation, chronic fatigue syndrome, lupus, alopecia areata, ankylosing spondylitis, antiphospholipid antibody syndrome, autoimmune skin disorders, Cushing's syndrome, scleroderma, Sjogren's syndrome, etc.

Gender and Cocaine Use Influence the Expression of Urinary Markers of Inflammation and Oxidative Stress

Gender and Cocaine Use Influence the Expression of Urinary Markers of Inflammation and Oxidative Stress Book
Author : Marie Meagher Bourgeois
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

ABSTRACT: The purpose of this study was to investigate whether or not gender differences may be present in the expression of a number of urinary proteins which may serve as markers of inflammation and oxidative stress. Males and females have different patterns of illness and different life spans, suggesting basic biological traits exert significant control on the incidence of rhabdomyolysis, renal failure, atherosclerosis, myocardial ischemia, myocardial contraction band formation, autoimmune disorders and general inflammatory diseases. Men are at greater risk for cardiovascular disease; however women, particularly elderly women, have higher fatality rates due to heart failure. Renal diseases progress far more quickly in men, possibly due to testosterone. Men also have higher kidney bulk related to androgen expression. Gender disparity may be most obvious in autoimmune disorders; of the estimated 8.5 million people diagnosed with autoimmune disorders, approximately 80% are women. Hashimoto's thyroiditis, the most common form of hypothyroidism, is up to 10 times more common in women. Systemic Lupus Erythematosus (SLE), an autoimmune disease characterized by acute and chronic inflammation, is 9 times more common in women. Rheumatoid arthritis (RA), an autoimmune disease affecting approximately 1.3 million people in the United States, is four times more common in women. Diabetes mellitus (DM), affecting more than 17 million people - the majority of which are women, is linked to microvascular and macrovascular diseases such as kidney failure, strokes and atherosclerosis. These conditions are linked to physiological changes that may alter the expression of certain biomarkers of inflammation and oxidative stress. Over the past several decades, it has become increasingly clear that the role of diet, smoking, and other lifestyle choices clearly influence the etiology and pathophysiology of these diseases. The use of drugs, both licit and illicit, has been clearly linked to many of these diseases. Illicit substances, particularly cocaine, have been demonstrated to produce pathophysiological changes to many systems in the body which can greatly influence the progression of existing and drug-induced disease states leading to systemic damage. A relationship between the expression of markers of inflammation, oxidative stress, cardiac damage, or other systemic injury, gender and cocaine use has not been clearly established. Urine is an important medium for assessment of general health status. It has classically been used to monitor disease states; glucosuria as an indicator of diabetes and renal dysfunction, microorganisms signifying urinary tract or bladder infection, and biomarkers such as human chorionic gonadotropin to confirm pregnancy. Recently urine has been used to assess biomarker expression and disease states. Urine is an ideal clinical tool for toxicological screens; it is readily accessible, non invasive and typically supplied in sufficient quantity to accommodate multiple tests. In this study, urine specimens were collected and analyzed for creatinine, cocaine, total protein, aldosterone, c-reactive protein (hsCRP), myeloperoxidase (MPO), microalbumin (MAB), neutrophil gelatinase-associated lipocalin (NGAL), heat shock protein 90alpha (hsp90alpha), vascular endothelial growth factor (VEGF), myoglobin, pro atrial natriuretic peptide (proANP) and interleukins 1alpha, 1 beta and 6 using ELISA and colorimetric assays. Urine specimens that tested negative for all illicit substances in the standard National Institute on Drug Abuse (NIDA) 10 panel showed differences in a number of these biomarkers which strongly suggested significant differences between males and females for aldosterone, IL1alpha and IL1beta. In addition, significance is suggested for MPO and CRP. Although sex specific differences in serum expression have been noted for some of the markers in both animal and human models, this has not been previously demonstrated in human urine. This may have implications for what is typically referred to as 'normal' values. Gender specific differences were not apparent in urine specimens that tested positive for cocaine. Also, in males only, the levels of myoglobin and aldosterone significantly increased.

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases Book
Author : Michael Lockshin,D. Ware Branch
Publisher : Gulf Professional Publishing
Release : 2006
ISBN : 0444518010
Language : En, Es, Fr & De

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Book Description :

This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy. * Authors share an academic interest in the unique relationship between being a woman and having an autoimmune disease * Touches on controversial topics, such as the mechanism of antiphospholipid-related fetal loss and whether or not non-steroidal anti-inflammatory agents should be used in pregnancy * Includes critical and balanced reviews of the controversial association between autoimmune disease and female infertility

Rheumatoid Arthritis Understanding Arthritis

Rheumatoid Arthritis  Understanding Arthritis  Book
Author : Dr Dennis Steve
Publisher : Unknown
Release : 2020-09-25
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Rheumatoid arthritis is a chronic inflammatory and autoimmune disease or disorder which means that your immune system mistakenly attacks healthy cells in your body, causing inflammation (painful swelling) in a wide variety of body system including the eyes, skin, lungs, heart and blood vessels. Rheumatoid arthritis mainly attacks the joints in the wrists, hands and knees. This book is designed to serve as a specific guide to everything you need to know about rheumatoid arthritis as a chronic autoimmune disease, the signs and symptoms of rheumatoid arthritis, the causes and risk factors of rheumatoid arthritis, the complications of rheumatoid arthritis, Diagnosis for rheumatoid arthritis. The manual will guide you on everything you need to know about autoimmune diseases, the causes, symptoms, treatment and other types of autoimmune disease. It will also guide you on what causes the immune system to rebel, the symptoms, diagnosis and treatment of toxic overload, triggers of immune system, rheumatoid arthritis diet and exercise, the Nutritional supplements for rheumatoid arthritis, most important organs for human health, energy healing for rheumatoid arthritis. The manual will guide you on the stem cell therapies for rheumatoid arthritis, low-dose naltrexone, medications, therapy options and surgery for rheumatoid arthritis, how to maintain a healthy lifestyle.

Reverse Inflammation Naturally

Reverse Inflammation Naturally Book
Author : Michelle Honda
Publisher : Hatherleigh Press
Release : 2017-05-30
ISBN : 1578266815
Language : En, Es, Fr & De

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Book Description :

Reverse Inflammation Naturally provides a comprehensive overview of both acute and chronic inflammation and offers practical guidance and alternative solutions to popular drugs as well as beneficial supplements and home remedies. Chronic inflammation is among the most prevalent ailments seen in modern society—and all too often, our diet and reliance on common over-the-counter medications is to blame. Not only does traditional medicine offer little in the way of safe, low-risk solutions, it is one of the leading causes of painful, unnecessary inflammation in patients of all ages. As a result, more patients are turning to the world of natural medicine. With Reverse Inflammation Naturally, you can learn how to work with your body to achieve effective heal­ing, see lasting results, and reclaim your life. Complete with healing remedies, dietary regimens, and protocols for every stage of heal­ing and maintenance, Reverse Inflammation Naturally contains step-by-step, do-it-yourself instructions and includes the most effective dietary programs and herbal supplements proven to help control—and reverse—the body’s inflammation response, all while promot­ing overall health and wellness. Reverse Inflammation Naturally covers a multitude of topics, including: • A comprehensive overview of inflammation, its causes, and its related ailments • Natural substitutes for popular over-the-counter and prescription medications • How best to prepare herbal remedies and supplements for a variety of uses • The latest information on clinical trials, medications, and alternative therapies • How to select the right supplements, vitamins, and nutrients for your needs …and many more! Featuring alternative solutions to potentially harmful prescription drugs, as well as safe food choices and a guide to herbal medicine, Reverse Inflammation Naturally helps you regain your sense of health and well-being.

Rheumatic Diseases in Women and Children

Rheumatic Diseases in Women and Children Book
Author : Shefali K Sharma,Sujata Sawhney
Publisher : JP Medical Ltd
Release : 2014-02-15
ISBN : 9351520811
Language : En, Es, Fr & De

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Book Description :

Concise guide to diagnosis and treatment of rheumatic diseases in pregnant women and in children.