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The Handbook Of Metabolic Phenotyping

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The Handbook of Metabolic Phenotyping

The Handbook of Metabolic Phenotyping Book
Author : John C. Lindon,Jeremy K. Nicholson,Elaine Holmes
Publisher : Elsevier
Release : 2018-10-04
ISBN : 0128122943
Language : En, Es, Fr & De

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Book Description :

The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping Explores, in detail, the many diverse statistical approaches used in the field Offers practical tips for successfully conducting metabolic phenotyping studies Features reviews of all of the various fields of activity relating to human studies

The Handbook of Metabonomics and Metabolomics

The Handbook of Metabonomics and Metabolomics Book
Author : John C. Lindon,Jeremy K. Nicholson,Elaine Holmes
Publisher : Elsevier
Release : 2011-08-11
ISBN : 9780080468006
Language : En, Es, Fr & De

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Book Description :

Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. * comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies * aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification * covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Measuring Metabolic Rates

Measuring Metabolic Rates Book
Author : John R. B. Lighton
Publisher : Oxford University Press, USA
Release : 2018-12-24
ISBN : 0198830394
Language : En, Es, Fr & De

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Book Description :

This is the only authoritative textbook on metabolic measurement of animals, ranging in mass from fruit flies to whales. It integrates a rigorous theoretical background with detailed practical guidelines for making actual measurements in the field and laboratory.

Encyclopedia of Analytical Science

Encyclopedia of Analytical Science Book
Author : Anonim
Publisher : Elsevier
Release : 2019-04-02
ISBN : 008101984X
Language : En, Es, Fr & De

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Book Description :

The third edition of the Encyclopedia of Analytical Science is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.g., forensic, environmental and clinical); and analytes (e.g., arsenic, nucleic acids and polycyclic aromatic hydrocarbons), providing a one-stop resource for analytical scientists. Offers readers a one-stop resource with access to information across the entire scope of modern analytical science Presents articles split into three broad areas: analytical techniques, areas of application and and analytes, creating an ideal resource for students, researchers and professionals Provides concise and accessible information that is ideal for non-specialists and readers from undergraduate levels and higher

The Oxford Handbook of Adult Cognitive Disorders

The Oxford Handbook of Adult Cognitive Disorders Book
Author : Michael L. Alosco,Robert A. Stern
Publisher : Oxford Library of Psychology
Release : 2019-06-03
ISBN : 0190664126
Language : En, Es, Fr & De

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Book Description :

The prevalence of adult cognitive disorders will dramatically rise over the next 25 years due to the aging population. Clinical research on adult cognitive disorders has rapidly evolved, including evidence of new adult cognitive disorders and greater insight into the clinical presentation, mechanism, diagnosis, and treatment of established diseases. The Oxford Handbook of Adult Cognitive Disorders is an up-to-date, scholarly, and comprehensive volume covering most diseases, conditions, and injuries resulting in impairments in cognitive function in adults. Topics covered include normal cognitive and brain aging, the impact of medical disorders and psychiatric illnesses on cognitive function, adult neurodevelopmental disorders, and various neurological conditions. This Handbook also provides a section on unique perspectives and special considerations for clinicians and clinical researchers, covering topics such as cognitive reserve, genetics, diversity, and neuroethics. Readers will be able to draw upon this volume to facilitate clinical practice (including differential diagnosis, treatment recommendations, assessment practices), and to obtain an in-depth review of current research across a wide spectrum of disorders, provided by leaders in their fields. The Oxford Handbook of Adult Cognitive Disorders is a one-of a kind resource appropriate for both clinicians and clinical researchers, from advanced trainees to seasoned professionals.

Metabolic Phenotyping in Personalized and Public Healthcare

Metabolic Phenotyping in Personalized and Public Healthcare Book
Author : Jeremy Nicholson,Ara Darzi,Elaine Holmes,John C. Lindon
Publisher : Academic Press
Release : 2016-02-11
ISBN : 0128004142
Language : En, Es, Fr & De

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Book Description :

Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches. In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream. Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making Discusses longitudinal sampling from individual patients for stratified medicine Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England

The Handbook of Plant Metabolomics

The Handbook of Plant Metabolomics Book
Author : Wolfram Weckwerth,Guenter Kahl
Publisher : John Wiley & Sons
Release : 2013-02-28
ISBN : 3527669906
Language : En, Es, Fr & De

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Book Description :

This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series this new book presents an excellent overview of different approaches and techniques in Metabolomics. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field. With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, the title meets a growing market. The Kahl books are in addition a trusted brand for the plant science community and have always sold above expectations.

Handbook of Non prescription Drugs

Handbook of Non prescription Drugs Book
Author : Anonim
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Non prescription Drugs book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Oxford Handbook of Developmental Behavioral Neuroscience

Oxford Handbook of Developmental Behavioral Neuroscience Book
Author : Mark Samuel Blumberg,John Henry Freeman,Scott R. Robinson
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Oxford Handbook of Developmental Behavioral Neuroscience book written by Mark Samuel Blumberg,John Henry Freeman,Scott R. Robinson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Drug Interactions

Handbook of Drug Interactions Book
Author : Ashraf Mozayani,Lionel Raymon
Publisher : Springer Science & Business Media
Release : 2003-10-15
ISBN : 1592596541
Language : En, Es, Fr & De

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Book Description :

A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Handbook of Basic Pharmacokinetics Including Clinical Applications

Handbook of Basic Pharmacokinetics   Including Clinical Applications Book
Author : Wolfgang A. Ritschel,Gregory L. Kearns,American Pharmaceutical Association
Publisher : Amer Pharmacists Assn
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A user-friendly handbook on the principles and techniques involved in the various applications of pharmacokinetics. Provides a concise reference for clinicians who need quick information on the pharmacokinetic characteristics of specific drugs. Thoroughly updated and revised, this book features pharmacokinetic data profiles on more than 600 drugs.

Handbook of Drug Therapy in Reproductive Endocrinology and Infertility

Handbook of Drug Therapy in Reproductive Endocrinology and Infertility Book
Author : Michel E. Rivlin
Publisher : Little Brown & Company
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Drug Therapy in Reproductive Endocrinology and Infertility book written by Michel E. Rivlin, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mass Spectrometry Handbook

Mass Spectrometry Handbook Book
Author : Mike S. Lee
Publisher : John Wiley & Sons
Release : 2012-04-16
ISBN : 1118180720
Language : En, Es, Fr & De

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Book Description :

Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Handbook of Clinical Pharmacology

Handbook of Clinical Pharmacology Book
Author : Felix Bochner
Publisher : Little, Brown Medical Division
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Clinical Pharmacology book written by Felix Bochner, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Handbook of Biological Therapy

The Handbook of Biological Therapy Book
Author : Bruce Kirkham,Arthur Kavanaugh,Scott Eric Plevy
Publisher : Oxford University Press
Release : 2008-11-27
ISBN : 0199208166
Language : En, Es, Fr & De

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Book Description :

Drugs produced by molecular biological techniques, called the 'biologics', differ from the usual chemical medications. Their optimum use, and the detection and managemenet of adverse events, pose a significant challenge to the clinician. Licences for new biologics continue to be granted for the likes of rituximab, abatacept and certocizumals pegol. Intensive research is also defining new areas in which these drugs will be used in the future, increasing the number of practitioners using biologics. As the use of these drugs increases around the world, so the level of information needed by primary care practitioners and specialist prescribers needs to be expanded The Handbook of Biological Therapy provides the practising clinician with a practica guide to the use of Tumour Necrosis Factor Blocking Therapy (TNF-blockers), and important new class of biologic therapy for rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, psoriasis, and psoriatic arthritis. It is a comprehensive distillation of the authors' clinical experience with these drugs, combined with data from diverse databases offering practical advice on their uses, specific indications, supporting clinical trial data and safety issues, with the aim of making the use of these drugs easier for the busy clinician. All of the authors have been involved from the beginnings of the clinical trial programmes with these drugs and continue to use them in daily practice.

Handbook of Clinical Neurology

Handbook of Clinical Neurology Book
Author : P. J. Vinken,G. W. Bruyn
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Clinical Neurology book written by P. J. Vinken,G. W. Bruyn, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

NMR in Pharmaceutical Science

NMR in Pharmaceutical Science Book
Author : Robin K. Harris
Publisher : John Wiley & Sons
Release : 2015-09-28
ISBN : 1118660250
Language : En, Es, Fr & De

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Book Description :

NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR principles and the unique contribution that NMR (including MRI) can provide. After an introductory chapter, which constitutes an overview, the content is organised into five sections. The first section is on the basics of NMR theory and relevant experimental methods. The rest follow a sequence based on the chronology of drug discovery and development, firstly 'Idea to Lead' then 'Lead to Drug Candidate', followed by 'Clinical Development', and finally 'Drug Manufacture'. The thirty one chapters cover a vast range of topics from analytical chemistry, including aspects involved in regulatory matters and in the prevention of fraud, to clinical imaging studies. Whilst this comprehensive volume will be essential reading for many scientists based in pharmaceutical and related industries, it should also be of considerable value to a much wider range of academic scientists whose research is related to the various aspects of pharmaceutical R&D; for them it will supply vital understanding of pharmaceutical industrial concerns and the basis of key decision making processes. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes

Handbook of Physiology

Handbook of Physiology Book
Author : American Physiological Society (1887- )
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Physiology book written by American Physiological Society (1887- ), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of hypertension

Handbook of hypertension Book
Author : W. H. Birkenhäger,J. L. Reid
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of hypertension book written by W. H. Birkenhäger,J. L. Reid, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pathology Laboratories Handbook

Pathology Laboratories Handbook Book
Author : Anonim
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Pathology Laboratories Handbook book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.