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The Guide To Investigation Of Mouse Pregnancy

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The Guide to Investigation of Mouse Pregnancy

The Guide to Investigation of Mouse Pregnancy Book
Author : B. Anne Croy,Aureo T. Yamada,Francesco J. DeMayo,S. Lee Adamson
Publisher : Academic Press
Release : 2013-12-09
ISBN : 0123947944
Language : En, Es, Fr & De

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Book Description :

The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications Describes the angiogenic tree the mother’s uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success

Pathology of the Developing Mouse

Pathology of the Developing Mouse Book
Author : Brad Bolon
Publisher : CRC Press
Release : 2015-04-24
ISBN : 1420070096
Language : En, Es, Fr & De

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Book Description :

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity. The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit: baseline anatomic and physiologic traits of developing mice principles of good experimental design and statistical analysis for mouse developmental pathology studies procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques; methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids; options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., "lesions") during development; and well-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).

Kaufman s Atlas of Mouse Development Supplement

Kaufman   s Atlas of Mouse Development Supplement Book
Author : Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay
Publisher : Academic Press
Release : 2015-09-23
ISBN : 0128009136
Language : En, Es, Fr & De

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Book Description :

Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures Offers in-depth anatomy and morphological views of organ systems Written descriptions convey developmental origins of the organ systems

Understanding the Materno Fetal Interface During Microbial Infections

Understanding the Materno Fetal Interface During Microbial Infections Book
Author : Demba Sarr,Ricardo E. Fretes,Ulrike Kemmerling,Sodiomon B. Sirima
Publisher : Frontiers Media SA
Release : 2020-12-11
ISBN : 2889662403
Language : En, Es, Fr & De

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Book Description :

Pregnancy is a physiologically and immunologically challenging health state. Immunological and physiological changes throughout the course of pregnancy make pregnant women usually susceptible to infection with microbial agents. Infections with pathogens during pregnancy can have devastating consequences to both the fetus and his/her mother. These infections are linked with adverse pregnancy outcomes. Infections with parasites, viruses, or bacteria can be associated with maternal anemia, abortion, intrauterine growth retardation, preterm delivery, fetal morbidity and high risk of mortality during the first years of life. Despite these significant consequences and complications associated with infections by microbial pathogens during the course of gestation, very little is known about the underlying mechanisms of the pathogenesis and immunopathology of infections during pregnancy. The Research Topic proposed here in, will focus on microbial infections during pregnancy. Studies and review papers addressing the pregnant host/fetus/pathogen interactions, the host/fetus immunological response against infections during gestation, trans-placental transfer of infections during pregnancy are welcome. Topics related to model systems used to mirror the biology in human, the pathogenesis and molecular pathways as well as the mechanisms of the disease at the maternofetal interface including the placenta, the amniotic fluid, and the fetal membranes will be considered making the scope and interest of the topic relatively broad. There is a growing number of pathogens associated with pregnancy. In most cases, women are more susceptible to infections with these pathogens when they become pregnant in comparison to their non-pregnant counterparts. Unfortunately, vertical transmission occurs in most cases but the underlying mechanisms are still unknown. The placenta has always been considered as a barrier against congenital infections but studies have indicated that microbial pathogens breach this barrier. The amniotic fluid, and the fetal membranes are also important components of vertical transmission because of their non-sterile state even in most healthy pregnancies. During pregnancy, infections by malaria or toxoplasmosis as well as other viral or bacterial pathogens lead to an uncontrolled inflammatory response recognized as a significant cause for preterm delivery and intra uterine growth retardation leading to low birth weight, a risk factor to infant morbidity and mortality. To successfully prevent, treat, eradicate or educate about microbial infections during pregnancy, we must understand the molecular mechanisms by which they cause poor birth outcomes including how vertical transmission occurs at the maternofetal interface.

Point Particles to Capture Polarized Embryonic Cells Cold Pools in the Atmosphere

Point Particles to Capture Polarized Embryonic Cells   Cold Pools in the Atmosphere Book
Author : Silas Boye Nissen
Publisher : Niels Bohr Institute, Faculty of Science, University of Copenhagen
Release : 2020-08-31
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Part 1: How are the incredible diversity and robustness compatible with animal morphologies? Based on apical-basal and planar cell polarities’ ubiquity, I suggest a 3D mathematical model: Point particles represent cells having zero, one, or two unit-arrows representing polarities. I test the model abilities on preimplantation development, sea urchin gastrulation, mammalian neurulation, organoid folding, and tubulogenesis. I find that a minimal, versatile toolbox, including cellular polarities, captures the emergence of diverse and robust animal morphologies. Part 2: How are deep convective events spatially organized in the tropical atmosphere? Here, I test the importance of atmospheric cold pools for organizing convection. I suggest a 2D mathematical model: Points expand into circles representing cold pools. When circles meet, a convective event occurs, and a new circle forms. I find this model captures convective scale increase and initial stages of convective self-aggregation. The latter is crucial due to its link to tropical cyclogenesis.

Reproduction in Mammals

Reproduction in Mammals Book
Author : Virginia Hayssen,Teri J. Orr
Publisher : JHU Press
Release : 2017-10-27
ISBN : 1421423162
Language : En, Es, Fr & De

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Book Description :

Readers will come away from this thought-provoking book with an understanding of not only how reproduction fits into the lives of female mammals but how biology has affected the enormously diverse reproductive patterns of the phenotypes we observe today.

The Vertebrate Blood Gas Barrier in Health and Disease

The Vertebrate Blood Gas Barrier in Health and Disease Book
Author : Andrew N. Makanya
Publisher : Springer
Release : 2015-08-27
ISBN : 3319183923
Language : En, Es, Fr & De

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Book Description :

This comprehensive volume on the blood-gas barrier (BGB) among vertebrates covers its structure and composition along with aspects of evolution, bioengineering, and morphometry. The book also discusses the embryological development of the BGB, including chronology of events and molecular control in vertebrates; modulation of the barrier function, including cyclic stretch-induced increases in alveolar epithelial permeability; mechanisms of lung vascular/epithelial permeability; transport mechanisms of the BGB, including sodium transport channels; factors affecting trans-barrier traffic of fluids, such as chronic elevation of pulmonary microvascular pressure; stress failure; regulation and repair in acute lung injury; chronic lung disease; and lung transportation. Ten authoritative chapters approach the blood-gas barrier holistically, from basic structure and development to pathology and treatment. Properties of the BGB are discussed in the earlier chapters, followed by prenatal and post-natal development and mechanisms of the healthy BGB. The latter half of the book delves into the pathology of the BGB, analyzing common afflictions and exploring options for treatment, including its alterations during lung transplantation. Intuitively structured and comprehensive, The Vertebrate Blood-Gas Barrier in Health and Disease is ideal for researchers and clinicians interested in pneumology and angiology.

Advances in Biomechanics and Tissue Regeneration

Advances in Biomechanics and Tissue Regeneration Book
Author : Mohamed Hamdy Doweidar
Publisher : Academic Press
Release : 2019-08-13
ISBN : 012816610X
Language : En, Es, Fr & De

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Book Description :

Advances in Biomechanics and Tissue Regeneration covers a wide range of recent development and advances in the fields of biomechanics and tissue regeneration. It includes computational simulation, soft tissues, microfluidics, the cardiovascular system, experimental methods in biomechanics, mechanobiology and tissue regeneration. The state-of-the-art, theories and application are presented, making this book ideal for anyone who is deciding which direction to take their future research in this field. In addition, it is ideal for everyone who is exploring new fields or currently working on an interdisciplinary project in tissue biomechanics. Combines new trends in biomechanical modelling and tissue regeneration Offers a broad scope, covering the entire field of tissue biomechanics Contains perspectives from engineering, medicine and biology, thus giving a holistic view of the field

Pericyte Biology in Different Organs

Pericyte Biology in Different Organs Book
Author : Alexander Birbrair
Publisher : Springer
Release : 2019-04-01
ISBN : 3030110931
Language : En, Es, Fr & De

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Book Description :

The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and vascular research. This volume explores pericytes' physiologic roles in different tissues, ranging from the pancreas, lungs and liver through skeletal muscle, gut, retina and more. Together with its companion volumes Pericyte Biology in Disease and Pericyte Biology – Novel Concepts, Pericyte Biology in Different Organs presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific organs.

Causes and Consequences of Intrauterine Growth Restriction

Causes and Consequences of Intrauterine Growth Restriction Book
Author : Elke Winterhager,Ivo Bendix,Suzanne Lee Miller
Publisher : Frontiers Media SA
Release : 2020-06-04
ISBN : 2889637689
Language : En, Es, Fr & De

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Book Description :

Download Causes and Consequences of Intrauterine Growth Restriction book written by Elke Winterhager,Ivo Bendix,Suzanne Lee Miller, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Investigation on Immunoglobulin Gamma IgG Allotypic Variants

Investigation on Immunoglobulin Gamma  IgG  Allotypic Variants Book
Author : Shu-Cai Huang
Publisher : Unknown
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Investigation on Immunoglobulin Gamma IgG Allotypic Variants book written by Shu-Cai Huang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Unofficial Guide to Getting Pregnant

The Unofficial Guide to Getting Pregnant Book
Author : Joan Liebmann-Smith,Jacqueline Nardi Egan,John J. Stangel, M.D.
Publisher : John Wiley & Sons
Release : 2005-10-13
ISBN : 0471781754
Language : En, Es, Fr & De

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Book Description :

The inside scoop... for when you want more than the official line! Once you decide to start a family, you may think pregnancy will occur quickly. However, it takes the average healthy young couple six months to a year to conceive. This guide helps you get in the best possible shape for conceiving, discussing conception and misconceptions in depth. If pregnancy doesn't happen "automatically," you're not alone; one in six couples have fertility problems. The Unofficial Guide to Getting Pregnant provides clear, unbiased guidance on the many confusing medical, emotional, and financial issues related to getting pregnant. This book objectively reviews state-of-the-art infertility treatments and procedures, including fertility drugs, corrective surgery, IVF, and the other assisted reproductive technologies. It also covers third-party procedures, such as sperm and egg donation and surrogacy. Vital Information few resources reveal--information that can help you zero in on the most effective, economical approach for you. Insider Secrets about choosing a specialist, potential legal issues with third-party procedures, and alternative treatments that might work. Money-Saving Information to help you compare the cost of different treatments, decipher state laws on insurance coverage, and more. Time-Saving Tips to avoid delays in diagnosing and treating problems while your biological clock is ticking. The Scoop on the newest fertility drugs, microsurgical techniques, and assisted reproductive technologies.

Guide to Techniques in Mouse Development Part A

Guide to Techniques in Mouse Development  Part A Book
Author : Anonim
Publisher : Academic Press
Release : 2010-08-04
ISBN : 9780080887784
Language : En, Es, Fr & De

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Book Description :

This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. This volume is an update of volume 225 of MIE, "Guide to Techniques in Mouse Development", edited by P.M. Wassarman and M.L. DePamphilis and published in 1993. During the past 17 years many new technologies or methodologies have appeared for the study of mouse development and this volume comprehensively covers these, including: new techniques for the cryopreservation of gametes and embryos, production of transgenic and null (knockout) animals (use of ES cells), generation of conditional/inducible mutant animals, use of gene-trap mutagenesis, analysis of allele-specific expresion, use of new reporter constructs, humanizing of transgenic animals, transcript profiling of mouse development, imaging of mouse development, rederivation of animals and use of mouse genomics.

Exposure of the Pregnant Patient to Diagnostic Radiations

Exposure of the Pregnant Patient to Diagnostic Radiations Book
Author : Louis K. Wagner,Richard G. Lester,Luis R. Saldana
Publisher : Lippincott Williams & Wilkins
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The editors address the anxiety-provoking, but not uncommon, scenario of a woman learning that she is pregnant after diagnostic or therapeutic radiologic exposure, or alternately, requiring X-rays, magnetic resonance, radioisotopes, or ultrasound after she becomes pregnant. Considerations span: the mechanisms for injury by diagnostic radiations, the units and measures of radiation, the amount of radiation absorbed by the conceptus, prenatal risk assessment, clinical management, and case reports (of diseases and traumatic injuries) exemplifying decision recommendations and counseling. Appendixes guide conceptus dose calculations for X-ray exams and radionuclide studies, and list half-lives of 23 radionuclides used in nuclear medicine (5,730 years for Carbon-14). Annotation copyrighted by Book News, Inc., Portland, OR

Drugs in Pregnancy and Lactation

Drugs in Pregnancy and Lactation Book
Author : Gerald G. Briggs,Roger K. Freeman,Sumner J. Yaffe
Publisher : Lippincott Williams & Wilkins
Release : 2011
ISBN : 1608317080
Language : En, Es, Fr & De

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Book Description :

An A-Z listing of drugs by generic name. Each monograph summarizes the known and/or possible effects of the drug on the fetus. It also summarizes the known/possible passage of the drug into the human breast milk. A careful and exhaustive summarization of the world literature as it relates to drugs in pregnancy and lactation. Each monograph contains six parts: Generic US name Pharmacologic class Risk factor Fetal risk summary Breast feeding summary References Features for this edition include: 1200 commonly prescribed drugs including 105 new drugs New mobile application to access the content on the go* Cross-referenced combination drugs New list of drugs contraindicated during breastfeeding New list of drugs contraindicated in pregnancy List of drugs known to cause human developmental toxicity More summaries at the beginning for pregnancy and breastfeeding Brand new trim size 8.5 x 11 4-color design Consistently formatted throughout Companion site includes fully searchable text and updates from the Briggs newsletter *App included with the book is a free version with limited content. An in-app purchase is available for an upgrade to the full app content. With the ever changing drug information and guidelines, make sure you have the most current edition of Briggs Drugs in Pregnancy and Lactation to provide your patients with the best care.

Placental Molecules in Hemodynamics Transport and Cellular Regulation

Placental Molecules in Hemodynamics  Transport  and Cellular Regulation Book
Author : Toshio Hata,Masaomi Takayama,Ichiro Taki,Jean-Michel Foidart
Publisher : University Rochester Press
Release : 1997
ISBN : 9781580460163
Language : En, Es, Fr & De

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Book Description :

Current placental research in Japan, reflecting the adoption of recent biochemical, immunochemical and microbiological knowledge and techniques, and the resulting observation of enzyme activity and transportation of a variety of substances utilising isolated BBM, BBMV, BM and BMV. Also Vol. 10: Early PregnancyCovering: Trophoblast invasion . Angiogenesis and Blood Vessels . Endocrine and Paracine Regulation. With the European Placenta Group

Early Pregnancy Factors

Early Pregnancy Factors Book
Author : Franz Ellendorff,Egon Koch
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Early Pregnancy Factors book written by Franz Ellendorff,Egon Koch, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Employment Safety and Health Guide

Employment Safety and Health Guide Book
Author : Anonim
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Includes original text of the Occupational safety and health act of 1970.

ACS Monograph

ACS Monograph Book
Author : American Chemical Society
Publisher : Unknown
Release : 1949
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download ACS Monograph book written by American Chemical Society, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Journal of the Animal Technicians Association

The Journal of the Animal Technicians Association Book
Author : Anonim
Publisher : Unknown
Release : 1964
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Journal of the Animal Technicians Association book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.