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The Evolution Of Molecular Biology

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The Evolution of Molecular Biology

The Evolution of Molecular Biology Book
Author : Kensal Van Holde,Jordanka Zlatanova
Publisher : Academic Press
Release : 2018-02-20
ISBN : 0128129182
Language : En, Es, Fr & De

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Book Description :

The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances–and an individual’s own research–have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery. Expands on the development of molecular biology from the convergence of two independent disciplines, biochemistry and genetics Discusses the value of molecular biology in a variety of applications Includes research ethics and the societal implications of research Emphasizes the human aspects of research and the consequences of such advances to society

Integrated Molecular Evolution

Integrated Molecular Evolution Book
Author : Scott Orland Rogers
Publisher : CRC Press
Release : 2016-06-08
ISBN : 1482230909
Language : En, Es, Fr & De

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Book Description :

Evolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics. Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on: Evolution of the genetic code Mendelian genetics and population genetics Natural selection Horizontal gene transfers Animal development and plant development Cancer Extraction of biological molecules Analytical methods Sequencing methods and sequencing analyses Omics Phylogenetics and phylogenetic networks Protein trafficking Human genomics More than 400 illustrations appear in this edition, doubling the number included in the first edition, and over 100 of these diagrams are now in color. The second edition combines and integrates extensive summaries of genetics and evolutionary biology in a manner that is accessible for students at either the graduate or undergraduate level. It also provides both the basic foundations of molecular evolution, such as the structure and function of DNA, RNA and proteins, as well as more advanced chapters reviewing analytical techniques for obtaining sequences, and interpreting and archiving molecular and genomic data.

Data Analysis in Molecular Biology and Evolution

Data Analysis in Molecular Biology and Evolution Book
Author : Xuhua Xia
Publisher : Springer Science & Business Media
Release : 2001-09-30
ISBN : 0792375009
Language : En, Es, Fr & De

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Book Description :

Data Analysis in Molecular Biology and Evolution introduces biologists to DAMBE, a proprietary, user-friendly computer program for molecular data analysis. The unique combination of this book and software will allow biologists not only to understand the rationale behind a variety of computational tools in molecular biology and evolution, but also to gain instant access to these tools for use in their laboratories. Data Analysis in Molecular Biology and Evolution serves as an excellent resource for advanced level undergraduates or graduates as well as for professionals working in the field.

Evolution

Evolution Book
Author : Douglas R. Green
Publisher : Cold Spring Harbor Symposia on
Release : 2011
ISBN : 9780879698706
Language : En, Es, Fr & De

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Book Description :

This volume presents the latest advances in research into evolution, focusing on the molecular bases for evolutionary change. Topics include the appearance of the first genetic material, the origins of cellular life, and genome evolution.

Evolutionary and Molecular Biology

Evolutionary and Molecular Biology Book
Author : Center for Theology and the Natural Sciences
Publisher : University of Notre Dame Press
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This collection of twenty-two research papers explores the creative interaction between evolutionary and molecular biology, philosophy, and theology. It is the result of the third of five international research conferences co-sponsored by the Vatican Observatory, Rome and the Center for Theology and the Natural Sciences, Berkeley. The over arching goal of these conferences is to support the engagement of constructive theology with the natural sciences and to investigate the philosophical and theological elements in ongoing theoretical research in the natural sciences. Contents: An extensive introduction (Robert John Russell), two recent statements on evolution and Christian faith by Pope John Paul II, and an interpretive essay by the Director of the Observatory, George V. Coyne, S. J., Section One: Scientific Background--evolutionary and molecular biology (Francisco J Ayala and Camilo J. Cela-Conde) and the possibility of the evolution of extraterrestrial life (Julian Chela-Flores); Section Two: Evolution and Divine Action-philosophical analyses of teleology in light of biology from the perspectives of a scientist (Francisco J. Ayala) and a theologian (Wesley J. Wildman), assessments of the evidence for teleology by scientists (Paul Davies and William R. Stroeger, S. J.), and theological arguments on divine action and evolution focusing on special providence (Robert John Russell) and on process theism (Charles Birch); Section Three: Religious Interpretations of Biological Themes--critique of evolution-based arguments for atheism and of science-based religion (George F. R. Ellis), Darwin's relation to natural theology and a feminist perspective on metaphors in evolution (Anne M. Clifford), evolution from a naturalist perspective and the challenge to religion (Willem B. Drees), bicultural evolution and the created co-creator (Philip Hefner), continuity and emergence, propensities, pain, and death in light of evolution, and constructive Christology from and Anglican perspective (Arthur Peacocke), original sin and saving grace in light of evolution from a trinitarian perspective (Denis Edwards), divine kenosis and the power of the future from an evolutionary and process perspective (John F. Haught), and a comparison of models of God in light of evolution (Ian G. Barbour); Section Four: Biology, Ethics, and the Problem of Evil-an evolutionary model of biological and moral altruism (Camilo J. Cela-Conde and Gisele Marty), supervenience as a response to the reduction of Morality to biology (Nancey Murphy), ethical and theological issues raised by gem-line genetic therapy (Ted Peters), and the problems of divine action and theodicy in light of human sinfulness and suffering in nature (Thomas F. Tracy). This series of conferences builds on the initial 1987 Vatican Observatory conference and its resulting publication, Physics, Philosophy and Theology: A Common Quest for Understanding (1988), and on the previous Jointly-sponsored conferences and their publications, Quantum Cosmology and the Laws of Nature (1993) and Chaos and Complexity (1995). Future conferences will focus on scientific topics including the neuroscience's, quantum physics, and quantum field theory.

Molecular Biology of Evolution

Molecular Biology of Evolution Book
Author : M. Prakash
Publisher : Discovery Publishing House
Release : 2008
ISBN : 9788183562683
Language : En, Es, Fr & De

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Book Description :

Download Molecular Biology of Evolution book written by M. Prakash, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Environmental Epigenetics

Environmental Epigenetics Book
Author : L. Joseph Su,Tung-chin Chiang
Publisher : Springer
Release : 2015-05-18
ISBN : 1447166787
Language : En, Es, Fr & De

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Book Description :

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Bioinformatics and Molecular Evolution

Bioinformatics and Molecular Evolution Book
Author : Paul G. Higgs,Teresa K. Attwood
Publisher : John Wiley & Sons
Release : 2013-04-30
ISBN : 1118697065
Language : En, Es, Fr & De

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Book Description :

In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.

Molecular Methods for Evolutionary Genetics

Molecular Methods for Evolutionary Genetics Book
Author : Virginie Orgogozo,Matthew V. Rockman
Publisher : Humana Press
Release : 2011-03-15
ISBN : 9781617792274
Language : En, Es, Fr & De

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Book Description :

We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD sequencing, Sequenom, microarrays, etc.). The volume concludes by focusing on methods to study candidate genes, from obtaining their sequences and analyzing their transcripts to experimentally manipulating their activities in vivo. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Molecular Methods for Evolutionary Genetics serves as a rich resource to biologists interested in evolution, whether they be specialists or beginners in molecular biology.

Molecular Biology of the Cell

Molecular Biology of the Cell Book
Author : Bruce Alberts
Publisher : Unknown
Release : 2004
ISBN : 9780815332183
Language : En, Es, Fr & De

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Book Description :

Download Molecular Biology of the Cell book written by Bruce Alberts, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Neutral Theory of Molecular Evolution

The Neutral Theory of Molecular Evolution Book
Author : Motoo Kimura
Publisher : Cambridge University Press
Release : 1983
ISBN : 9780521317931
Language : En, Es, Fr & De

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Book Description :

This book is the first comprehensive treatment of this subject.

Molecular Evolution

Molecular Evolution Book
Author : Roderick D.M. Page,Edward C. Holmes
Publisher : John Wiley & Sons
Release : 2009-07-14
ISBN : 1444313363
Language : En, Es, Fr & De

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Book Description :

The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

Molecular Evolution and Population Genetics for Marine Biologists

Molecular Evolution and Population Genetics for Marine Biologists Book
Author : Yuri Kartavtsev
Publisher : CRC Press
Release : 2015-08-24
ISBN : 1498701612
Language : En, Es, Fr & De

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Book Description :

Research in modern experimental and theoretical population genetics has been strengthened by advances in molecular techniques for the analysis of genetic variability. The evolutionary relationships of organisms may be investigated by comparing DNA sequences. This book covers chapters on population genetics, DNA polymorphism, genetic homeostasis, an

My Thoughts on Biological Evolution

My Thoughts on Biological Evolution Book
Author : Motoo Kimura
Publisher : Springer Nature
Release : 2020-07-29
ISBN : 9811561656
Language : En, Es, Fr & De

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Book Description :

This book, written by Motoo Kimura (1924–94), is a classic in evolutionary biology. In 1968, Kimura proposed the “neutral theory of molecular evolution”, which became the theoretical basis of modern evolutionary studies. After publishing his work in 1983 in the book “Neutral Theory of Molecular Evolution”, Kimura wrote this book in 1988 for the general public. It was originally written in Japanese and is translated here for the first time. In the book, Kimura first summarizes the development of evolutionary theory since Lamarck and Darwin. He then shows how the search for mechanisms of evolution developed into population genetics and describes how the study of molecular evolution matured by taking in the fruits of molecular biology. Kimura proceeds to carefully explain his neutral evolution theory at the molecular level. Finally, he presents his view of the world from an evolutionary perspective. The book has long served as an in-depth introduction to evolutionary biology for students and young researchers in Japan. There has been remarkably rapid progress in the field of bioscience at the molecular level over the past 30 years. Nevertheless, the book remains an important contribution that laid the foundations for what followed in molecular evolutionary studies.

Molecular Biology

Molecular Biology Book
Author : David P. Clark,Nanette J. Pazdernik
Publisher : Elsevier
Release : 2012-03-20
ISBN : 0123785952
Language : En, Es, Fr & De

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Book Description :

Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. The new Academic Cell Study Guide features all the articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. An updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. This text is designed for undergraduate students taking a course in Molecular Biology and upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and Agriculture. NEW: "Focus On Relevant Research" sections integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. NEW: Academic Cell Study Guide features all articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. NEW: Animations provided include topics in protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE Updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA Updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. Fully revised art program

Landmark Experiments in Molecular Biology

Landmark Experiments in Molecular Biology Book
Author : Michael Fry
Publisher : Academic Press
Release : 2016-06-10
ISBN : 012802108X
Language : En, Es, Fr & De

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Book Description :

Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling

Cancer Evolution

Cancer Evolution Book
Author : Charles Swanton
Publisher : Perspectives Cshl
Release : 2017
ISBN : 9781621821434
Language : En, Es, Fr & De

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Book Description :

Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.

Human Mitochondrial DNA and the Evolution of Homo sapiens

Human Mitochondrial DNA and the Evolution of Homo sapiens Book
Author : Hans-Jürgen Bandelt,Martin Richards,Vincent Macaulay
Publisher : Springer Science & Business Media
Release : 2006-09-05
ISBN : 3540317899
Language : En, Es, Fr & De

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Book Description :

Mitochondrial DNA is one of the most closely explored genetic systems, because it can tell us so much about the human past. This book takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents a comprehensive global picture and a critical appraisal of human mitochondrial DNA variation.

Gene Sharing and Evolution

Gene Sharing and Evolution Book
Author : Joram PIATIGORSKY,Joram Piatigorsky
Publisher : Harvard University Press
Release : 2009-06-30
ISBN : 0674042123
Language : En, Es, Fr & De

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Book Description :

In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.

Directed Enzyme Evolution

Directed Enzyme Evolution Book
Author : Frances H. Arnold,George Georgiou
Publisher : Springer Science & Business Media
Release : 2008-02-02
ISBN : 1592593968
Language : En, Es, Fr & De

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Book Description :

Directed evolution comprises two distinct steps that are typically applied in an iterative fashion: (1) generating molecular diversity and (2) finding among the ensemble of mutant sequences those proteins that perform the desired fu- tion according to the specified criteria. In many ways, the second step is the most challenging. No matter how cleverly designed or diverse the starting library, without an effective screening strategy the ability to isolate useful clones is severely diminished. The best screens are (1) high throughput, to increase the likelihood that useful clones will be found; (2) sufficiently sen- tive (i. e. , good signal to noise) to allow the isolation of lower activity clones early in evolution; (3) sufficiently reproducible to allow one to find small improvements; (4) robust, which means that the signal afforded by active clones is not dependent on difficult-to-control environmental variables; and, most importantly, (5) sensitive to the desired function. Regarding this last point, almost anyone who has attempted a directed evolution experiment has learned firsthand the truth of the dictum “you get what you screen for. ” The protocols in Directed Enzyme Evolution describe a series of detailed p- cedures of proven utility for directed evolution purposes. The volume begins with several selection strategies for enzyme evolution and continues with assay methods that can be used to screen enzyme libraries. Genetic selections offer the advantage that functional proteins can be isolated from very large libraries s- ply by growing a population of cells under selective conditions.