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The Era Of Artificial Intelligence And Machine Learning In The Pharmaceutical Industry

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The Era of Artificial Intelligence Machine Learning and Data Science in the Pharmaceutical Industry

The Era of Artificial Intelligence  Machine Learning  and Data Science in the Pharmaceutical Industry Book
Author : Stephanie K. Ashenden
Publisher : Academic Press
Release : 2021-04-23
ISBN : 0128204494
Language : En, Es, Fr & De

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Book Description :

The Era of Artificial Intelligence, Machine Learning and Data Science in the Pharmaceutical Industry examines the drug discovery process, assessing how new technologies have improved effectiveness. Artificial intelligence and machine learning are considered the future for a wide range of disciplines and industries, including the pharmaceutical industry. In an environment where producing a single approved drug costs millions and takes many years of rigorous testing prior to its approval, reducing costs and time is of high interest. This book follows the journey that a drug company takes when producing a therapeutic, from the very beginning to ultimately benefitting a patient’s life. This comprehensive resource will be useful to those working in the pharmaceutical industry, but will also be of interest to anyone doing research in chemical biology, computational chemistry, medicinal chemistry and bioinformatics. Demonstrates how the prediction of toxic effects is performed, how to reduce costs in testing compounds, and its use in animal research Written by the industrial teams who are conducting the work, showcasing how the technology has improved and where it should be further improved Targets materials for a better understanding of techniques from different disciplines, thus creating a complete guide

Artificial Intelligence in Healthcare

Artificial Intelligence in Healthcare Book
Author : Adam Bohr,Kaveh Memarzadeh
Publisher : Academic Press
Release : 2020-06-21
ISBN : 0128184396
Language : En, Es, Fr & De

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Book Description :

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Artificial Intelligence in Drug Discovery

Artificial Intelligence in Drug Discovery Book
Author : Nathan Brown
Publisher : Royal Society of Chemistry
Release : 2020-11-11
ISBN : 1839160543
Language : En, Es, Fr & De

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Book Description :

Following significant advances in deep learning and related areas interest in artificial intelligence (AI) has rapidly grown. In particular, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as predicting properties, designing molecules and optimising synthetic routes. Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline specific challenges including designing new molecular structures, synthesis planning and simulation. Providing a wealth of information from leading experts in the field this book is ideal for students, postgraduates and established researchers in both industry and academia.

Machine Learning and the Internet of Medical Things in Healthcare

Machine Learning and the Internet of Medical Things in Healthcare Book
Author : Krishna Kant Singh,Mohamed Elhoseny,Akansha Singh,Ahmed A. Elngar
Publisher : Academic Press
Release : 2021-04-26
ISBN : 012823217X
Language : En, Es, Fr & De

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Book Description :

Machine Learning and the Internet of Medical Things in Healthcare discusses the applications and challenges of machine learning for healthcare applications. The book provides a platform for presenting machine learning-enabled healthcare techniques and offers a mathematical and conceptual background of the latest technology. It describes machine learning techniques along with the emerging platform of the Internet of Medical Things used by practitioners and researchers worldwide. The book includes deep feed forward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology. It also presents the concepts of the Internet of Things, the set of technologies that develops traditional devices into smart devices. Finally, the book offers research perspectives, covering the convergence of machine learning and IoT. It also presents the application of these technologies in the development of healthcare frameworks. Provides an introduction to the Internet of Medical Things through the principles and applications of machine learning Explains the functions and applications of machine learning in various applications such as ultrasound imaging, biomedical signal processing, robotics, and biomechatronics Includes coverage of the evolution of healthcare applications with machine learning, including Clinical Decision Support Systems, artificial intelligence in biomedical engineering, and AI-enabled connected health informatics, supported by real-world case studies

Data Analytics in Bioinformatics

Data Analytics in Bioinformatics Book
Author : Rabinarayan Satpathy,Tanupriya Choudhury,Suneeta Satpathy,Sachi Nandan Mohanty,Xiaobo Zhang
Publisher : John Wiley & Sons
Release : 2021-01-20
ISBN : 111978560X
Language : En, Es, Fr & De

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Book Description :

Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.

Artificial Intelligence in Medicine

Artificial Intelligence in Medicine Book
Author : David Riaño,Szymon Wilk,Annette ten Teije
Publisher : Springer
Release : 2019-06-19
ISBN : 303021642X
Language : En, Es, Fr & De

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Book Description :

This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning.

Artificial Intelligence and Machine Learning for Healthcare

Artificial Intelligence and Machine Learning for Healthcare Book
Author : Chee Peng Lim,Ashlesha Vaidya,Yen-Wei Chen,Vaishnavi Jain,Lakhmi C. Jain
Publisher : Springer Nature
Release : 2022-09-29
ISBN : 3031111702
Language : En, Es, Fr & De

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Book Description :

In line with advances in digital and computing systems, artificial intelligence (AI) and machine learning (ML) technologies have transformed many aspects of medical and healthcare services, delivering tangible benefits to patents and the general public. This book is a sequel of the edition on “Artificial Intelligence and Machine Learning for Healthcare”. The first volume is focused on utilization of AI and ML for image and data analytics in the medical and healthcare domains. In this second volume, emerging methodologies and future trends in AI and ML for advancing medical treatments and healthcare services are presented. The selected studies in this book provide readers a glimpse on current progresses in AI and ML for undertaking a variety of healthcare-related tasks. The advances in AI and ML technologies for future healthcare are also discussed, shedding light on the potential of AI and ML to realize the next-generation medical treatments and healthcare services for the betterment of our global society.

Artificial Intelligence in Drug Design

Artificial Intelligence in Drug Design Book
Author : Alexander Heifetz
Publisher : Humana
Release : 2021-11-04
ISBN : 9781071617861
Language : En, Es, Fr & De

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Book Description :

This volume looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and unique, Artificial Intelligence in Drug Design is a valuable resource for structural and molecular biologists, computational and medicinal chemists, pharmacologists and drug designers.

Bioinformatics Tools for Pharmaceutical Drug Product Development

Bioinformatics Tools for Pharmaceutical Drug Product Development Book
Author : Vivek Chavda,K. Anand,Vasso Apostolopoulos
Publisher : John Wiley & Sons
Release : 2023-03-14
ISBN : 1119865115
Language : En, Es, Fr & De

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Book Description :

BIOINFORMATICS TOOLS FOR Pharmaceutical DRUG PRODUCT DLEVELOPMENT A timely book that details bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies, for drug development in the pharmaceutical and medical sciences industries. The book contains 17 chapters categorized into 3 sections. The first section presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. The following 2 sections include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall. Readers will find in this book: Applications of bioinformatics tools for pharmaceutical drug product development like process development, pre-clinical development, clinical development, commercialization of the product, etc.; The ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach; The broad and deep background, as well as updates, on recent advances in both medicine and AI/ML that enable the application of these cutting-edge bioinformatics tools. Audience The book will be used by researchers and scientists in academia and industry including drug developers, computational biochemists, bioinformaticians, immunologists, pharmaceutical and medical sciences, as well as those in artificial intelligence and machine learning.

Machine Learning for Critical Internet of Medical Things

Machine Learning for Critical Internet of Medical Things Book
Author : Fadi Al-Turjman,Anand Nayyar
Publisher : Springer Nature
Release : 2022-02-03
ISBN : 3030809285
Language : En, Es, Fr & De

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Book Description :

This book discusses the applications, challenges, and future trends of machine learning in medical domain, including both basic and advanced topics. The book presents how machine learning is helpful in smooth conduction of administrative processes in hospitals, in treating infectious diseases, and in personalized medical treatments. The authors show how machine learning can also help make fast and more accurate disease diagnoses, easily identify patients, help in new types of therapies or treatments, model small-molecule drugs in pharmaceutical sector, and help with innovations via integrated technologies such as artificial intelligence as well as deep learning. The authors show how machine learning also improves the physician’s and doctor’s medical capabilities to better diagnosis their patients. This book illustrates advanced, innovative techniques, frameworks, concepts, and methodologies of machine learning that will enhance the efficiency and effectiveness of the healthcare system. Provides researchers in machine and deep learning with a conceptual understanding of various methodologies of implementing the technologies in medical areas; Discusses the role machine learning and IoT play into locating different virus and diseases across the globe, such as COVID-19, Ebola, and cervical cancer; Includes fundamentals and advances in machine learning in the medical field, supported by significant case studies and practical applications.

Artificial Intelligence in Pharmaceutical Sciences Drug Discovery

Artificial Intelligence in Pharmaceutical Sciences  Drug Discovery  Book
Author : Dr Amit Gangwal
Publisher : Unknown
Release : 2020-08
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The book has been designed to cover all the basic topics and examples related to disruptive innovations and industry 4.0 in general and in particular, pharmaceutical sciences and other branches of healthcare sectors like medical and diagnostic. Major disruption is due to the advent of Artificial Intelligence, Machine Learning, Deep Learning, Blockchain, 3D Organ Printing and others. The book is ahead of its time in the sense that in entire country there is no such subject which is being taught in pharmacy, nursing or medical courses. By the time it becomes part of syllabus, this book is among the best resources in a compiled format for healthcare professionals, academicians and students of pharmacy besides those want to learn from the basic; as content beyond syllabus tool. All the content has been compiled after referring and mining hundreds of latest and original first-hand updates from inventors, experts, organizations (who/which are engaged in drug discovery research directly or indirectly through Artificial Intelligence) like Insilico, Google, Microsoft, INVIDIA, Novartis, Intel, IBM etc. All topics are explained in very simple language with clear aim and outcome using flow charts, tables and infographics of original creators. Professionals from medical, pharmacy, nursing and dental and medical imaging arena will find this book very useful. Students of all levels will find book very beneficial as few topics have been just touched, few have been shallow in complexity and rest are covered in detail. Full precautions have been exercised to address the needs of biology group students so that they can easily and effortlessly understand the subject matter of this book, which requires mathematical skills to grasp the basics of AI. Recent examples from various corporates, universities and daily life have found place in this unique book in a very explicit manner. In initial two chapters, background information has been explained with various comparison and examples, while third chapter focuses on application of Artificial Intelligence in drug discovery, repurposing, in advance, faster and accurate diagnosis of diseases. Last chapter throws a light on insights pertaining to ethical issues in AI research; and laws related to intellectual property rights on products/services borne owing to success (partly or purely and fully) derived by machines or devices through AI programs/algorithms. At the end of each chapter, questions have been added for the readers, mainly students.

Artificial Intelligence for Drug Development Precision Medicine and Healthcare

Artificial Intelligence for Drug Development  Precision Medicine  and Healthcare Book
Author : Mark Chang
Publisher : CRC Press
Release : 2020-05-12
ISBN : 1000767302
Language : En, Es, Fr & De

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Book Description :

Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science and statistics. While much of machine-learning is statistics-based, achievements in deep learning for image and language processing rely on computer science’s use of big data. Aimed at those with a statistical background who want to use their strengths in pursuing AI research, the book: · Covers broad AI topics in drug development, precision medicine, and healthcare. · Elaborates on supervised, unsupervised, reinforcement, and evolutionary learning methods. · Introduces the similarity principle and related AI methods for both big and small data problems. · Offers a balance of statistical and algorithm-based approaches to AI. · Provides examples and real-world applications with hands-on R code. · Suggests the path forward for AI in medicine and artificial general intelligence. As well as covering the history of AI and the innovative ideas, methodologies and software implementation of the field, the book offers a comprehensive review of AI applications in medical sciences. In addition, readers will benefit from hands on exercises, with included R code.

Intelligent Decision Support Systems A Journey to Smarter Healthcare

Intelligent Decision Support Systems   A Journey to Smarter Healthcare Book
Author : Smaranda Belciug,Florin Gorunescu
Publisher : Springer
Release : 2019-03-20
ISBN : 3030143546
Language : En, Es, Fr & De

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Book Description :

The goal of this book is to provide, in a friendly and refreshing manner, both theoretical concepts and practical techniques for the important and exciting field of Artificial Intelligence that can be directly applied to real-world healthcare problems. Healthcare – the final frontier. Lately, it seems like Pandora opened the box and evil was released into the world. Fortunately, there was one thing left in the box: hope. In recent decades, hope has been increasingly represented by Intelligent Decision Support Systems. Their continuing mission: to explore strange new diseases, to seek out new treatments and drugs, and to intelligently manage healthcare resources and patients. Hence, this book is designed for all those who wish to learn how to explore, analyze and find new solutions for the most challenging domain of all time: healthcare.

Artificial Intelligence in Medical Imaging

Artificial Intelligence in Medical Imaging Book
Author : Erik R. Ranschaert,Sergey Morozov,Paul R. Algra
Publisher : Springer
Release : 2019-01-29
ISBN : 3319948784
Language : En, Es, Fr & De

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Book Description :

This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implications for radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.

Artificial Intelligence in Medical Imaging

Artificial Intelligence in Medical Imaging Book
Author : Lia Morra,Silvia Delsanto,Loredana Correale
Publisher : CRC Press
Release : 2019-11-25
ISBN : 1000753085
Language : En, Es, Fr & De

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Book Description :

This book, written by authors with more than a decade of experience in the design and development of artificial intelligence (AI) systems in medical imaging, will guide readers in the understanding of one of the most exciting fields today. After an introductory description of classical machine learning techniques, the fundamentals of deep learning are explained in a simple yet comprehensive manner. The book then proceeds with a historical perspective of how medical AI developed in time, detailing which applications triumphed and which failed, from the era of computer aided detection systems on to the current cutting-edge applications in deep learning today, which are starting to exhibit on-par performance with clinical experts. In the last section, the book offers a view on the complexity of the validation of artificial intelligence applications for commercial use, describing the recently introduced concept of software as a medical device, as well as good practices and relevant considerations for training and testing machine learning systems for medical use. Open problematics on the validation for public use of systems which by nature continuously evolve through new data is also explored. The book will be of interest to graduate students in medical physics, biomedical engineering and computer science, in addition to researchers and medical professionals operating in the medical imaging domain, who wish to better understand these technologies and the future of the field. Features: An accessible yet detailed overview of the field Explores a hot and growing topic Provides an interdisciplinary perspective

Artificial Intelligence Platform For Molecular Targeted Therapy A Translational Science Approach

Artificial Intelligence Platform For Molecular Targeted Therapy  A Translational Science Approach Book
Author : Ariel Fernandez
Publisher : World Scientific
Release : 2021-03-12
ISBN : 9811232326
Language : En, Es, Fr & De

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Book Description :

In the era of big biomedical data, there are many ways in which artificial intelligence (AI) is likely to broaden the technological base of the pharmaceutical industry. Cheminformatic applications of AI involving the parsing of chemical space are already being implemented to infer compound properties and activity. By contrast, dynamic aspects of the design of drug/target interfaces have received little attention due to the inherent difficulties in dealing with physical phenomena that often do not conform to simplifying views.This book focuses precisely on dynamic drug/target interfaces and argues that the true game change in pharmaceutical discovery will come as AI is enabled to solve core problems in molecular biophysics that are intimately related to rational drug design and drug discovery.Here are a few examples to convey the flavor of our quest: How do we therapeutically impair a dysfunctional protein with unknown structure or regulation but known to be a culprit of disease? In regards to SARS-CoV-2, what is the structural impact of a dominant mutation?, how does the structure change translate into a fitness advantage?, what new therapeutic opportunity arises? How do we extend molecular dynamics simulations to realistic timescales, to capture the rare events associated with drug targeting in vivo? How do we control specificity in drug design to selectively remove side effects? This is the type of problems, directly related to the understanding of drug/target interfaces, that the book squarely addresses by leveraging a comprehensive AI-empowered approach.

AI and education

AI and education Book
Author : Miao, Fengchun,Holmes, Wayne,Ronghuai Huang,Hui Zhang,UNESCO
Publisher : UNESCO Publishing
Release : 2021-04-08
ISBN : 9231004476
Language : En, Es, Fr & De

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Book Description :

Artificial Intelligence (AI) has the potential to address some of the biggest challenges in education today, innovate teaching and learning practices, and ultimately accelerate the progress towards SDG 4. However, these rapid technological developments inevitably bring multiple risks and challenges, which have so far outpaced policy debates and regulatory frameworks. This publication offers guidance for policy-makers on how best to leverage the opportunities and address the risks, presented by the growing connection between AI and education. It starts with the essentials of AI: definitions, techniques and technologies. It continues with a detailed analysis of the emerging trends and implications of AI for teaching and learning, including how we can ensure the ethical, inclusive and equitable use of AI in education, how education can prepare humans to live and work with AI, and how AI can be applied to enhance education. It finally introduces the challenges of harnessing AI to achieve SDG 4 and offers concrete actionable recommendations for policy-makers to plan policies and programmes for local contexts. [Publisher summary, ed]

Artificial Intelligence in Oncology Drug Discovery and Development

Artificial Intelligence in Oncology Drug Discovery and Development Book
Author : John Cassidy,Belle Taylor
Publisher : BoD – Books on Demand
Release : 2020-09-09
ISBN : 1789846897
Language : En, Es, Fr & De

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Book Description :

There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is limiting the target market of each new medicine. Even as the global economic burden of cancer increases, the current paradigm in drug development is unsustainable. In this book, we discuss the development of techniques in machine learning for improving the efficiency of oncology drug development and delivering cost-effective precision treatment. We consider how to structure data for drug repurposing and target identification, how to improve clinical trials and how patients may view artificial intelligence.

Man Machine Environment System Engineering

Man Machine Environment System Engineering Book
Author : Shengzhao Long,Balbir S. Dhillon
Publisher : Springer Nature
Release : 2022-08-20
ISBN : 9811947864
Language : En, Es, Fr & De

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Book Description :

Man-Machine-Environment System Engineering: Proceedings of the 22nd Conference on MMESE are an academic showcase of the best papers selected from more than 500 submissions, introducing readers to the top research topics and the latest developmental trends in the theory and application of MMESE. This proceedings are interdisciplinary studies on the concepts and methods of physiology, psychology, system engineering, computer science, environment science, management, education, and other related disciplines. Researchers and professionals who study an interdisciplinary subject crossing above disciplines or researchers on MMESE subject will be mainly benefited from this proceedings MMESE primarily focuses on the relationship between Man, Machine and Environment, studying the optimum combination of man-machine-environment systems. In this system, “Man” refers to working people as the subject in the workplace (e.g. operators, decision-makers); “Machine” is the general name for any object controlled by Man (including tools, machinery, computers, systems and technologies), and “Environment” describes the specific working conditions under which Man and Machine interact (e.g. temperature, noise, vibration, hazardous gases etc.). The three goals of optimization of the man-machine-environment systems are to ensure safety, efficiency and economy. The integrated and advanced science research topic Man-Machine-Environment System Engineering (MMESE) was first established in China by Professor Shengzhao Long in 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian. In a letter to Shengzhao Long from October 22nd, 1993, Xuesen Qian wrote: “You have created a very important modern science and technology in China!”

Practical Deep Learning for Cloud Mobile and Edge

Practical Deep Learning for Cloud  Mobile  and Edge Book
Author : Anirudh Koul,Siddha Ganju,Meher Kasam
Publisher : "O'Reilly Media, Inc."
Release : 2019-10-14
ISBN : 1492034819
Language : En, Es, Fr & De

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Book Description :

Whether you’re a software engineer aspiring to enter the world of deep learning, a veteran data scientist, or a hobbyist with a simple dream of making the next viral AI app, you might have wondered where to begin. This step-by-step guide teaches you how to build practical deep learning applications for the cloud, mobile, browsers, and edge devices using a hands-on approach. Relying on years of industry experience transforming deep learning research into award-winning applications, Anirudh Koul, Siddha Ganju, and Meher Kasam guide you through the process of converting an idea into something that people in the real world can use. Train, tune, and deploy computer vision models with Keras, TensorFlow, Core ML, and TensorFlow Lite Develop AI for a range of devices including Raspberry Pi, Jetson Nano, and Google Coral Explore fun projects, from Silicon Valley’s Not Hotdog app to 40+ industry case studies Simulate an autonomous car in a video game environment and build a miniature version with reinforcement learning Use transfer learning to train models in minutes Discover 50+ practical tips for maximizing model accuracy and speed, debugging, and scaling to millions of users