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The Endocannabinoid System

The Endocannabinoid System Book
Author : Eric Murillo-Rodríguez
Publisher : Academic Press
Release : 2017-06-01
ISBN : 9780128096666
Language : En, Es, Fr & De

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Book Description :

The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field, and shed light on the many brain disorders this biological system is involved in. Written by world-leading experts in the field, the topics covered in this book will have a positive impact in the area of molecular biology, including but not limited to cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics. An introduction to endocannabinoids in the central nervous system and an overview to their functions in the brain Provides information on neurobiological and cellular studies on the role of the cannabinoid signalling system and its implications in human diseases Includes well-written overviews of the basics of endocannabinoid system structure and function written by expert authors from all over the world. Well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts

Behavioral Neurobiology of the Endocannabinoid System

Behavioral Neurobiology of the Endocannabinoid System Book
Author : Dave Kendall,Stephen Alexander
Publisher : Springer Science & Business Media
Release : 2009-08-14
ISBN : 9783540889557
Language : En, Es, Fr & De

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Book Description :

The endocannabinoid signaling system is a key modulator of central nervous function. This volume, essential reading for interested neuroscientists, provides in-depth coverage of the roles of the endocannabinoid signaling system in the neurobiology of behavior.

The endocannabinoid system a key modulator of emotions and cognition

The endocannabinoid system  a key modulator of emotions and cognition Book
Author : Patrizia Campolongo
Publisher : Frontiers E-books
Release : 2021-07-29
ISBN : 2889190854
Language : En, Es, Fr & De

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Book Description :

Download The endocannabinoid system a key modulator of emotions and cognition book written by Patrizia Campolongo, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Healing with Cannabis

Healing with Cannabis Book
Author : Cheryl Pellerin
Publisher : Simon and Schuster
Release : 2020-08-04
ISBN : 1510751904
Language : En, Es, Fr & De

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Book Description :

An Informative Read for an Audience Interested in Why and How Medical Cannabis Helps Treat a Range of Illnesses—Maybe All of Them With cannabis approved in fourteen states (including the District and two US territories), medical cannabis approved in at least 35 states, and hemp (very-low-THC cannabis) off the controlled substances list, millions now treat their ills with medical cannabis or non-intoxicating cannabinoids like CBD. But lots of them don’t know why or how cannabis works in the body. Healing with Cannabis informs readers about an ancient biological system newly discovered in every vertebrate on the planet—the endocannabinoid system. This system is the only reason cannabis works in the body, and it’s why cannabis is effective in a broad range of disorders. The book offers an informal tone, a little humor, interviews with some of the most knowledgeable cannabinoid scientists, color images, and a selection of research and clinical trials to recount the story of the endocannabinoid system, its origins in the earliest forms of life on Earth, the evolution of its elements, and the discoveries, millions of years later, of more of its elements over time. Healing with Cannabis explains the surprising reasons evolution conserved the endocannabinoid system over a billion years and tells specifically how cannabis has positive effects on some of society’s most devastating illnesses, including neurodegenerative diseases, post-traumatic stress disorder, pain, movement disorders, cancer and chemotherapy, and addiction. The book also shows how medical cannabis, widely available, will change the face of public health, and how nearly everyone can benefit from this versatile medicine that has a 5,000-year history of safe and effective use.

Role of the Endocannabinoid System in Islets of Langerhans

Role of the Endocannabinoid System in Islets of Langerhans Book
Author : Chen Li,King's College London. Guy's, King's and St. Thomas's School of Biomedical Sciences. Division of Reproduction & Endocrinology. Diabetes Research Group
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The endocannabinoid system is composed of a family of locally produced endogenous cannabimimetic phospholipid derivatives, the cannabinoid receptors and enzymes for endocannabinoid biosynthesis and degradation. Two subtypes of cannabinoid receptor, CB1 and CB2, have been cloned, and their activation is coupled to inhibition of adenylate cyclase or alterations in Ca2+ levels. The well-known appetite-inducing effects of cannabis are mediated by activation of cannabinoid receptors and the endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG) are abundantly present in key brain areas participating in the regulation of food intake and satiety. CB1 receptors have been pharmacologically targeted to provide therapies for appetite suppression and there is considerable interest in the regulatory role of CB1 receptors in metabolic balance. Currently, there is little information available on the functional roles of CB2 receptors, nor on the related GPR55 receptor which has been identified as a novel cannabinoid receptor. Given the key roles of islet [3-cells in maintaining fuel homeostasis and the established involvement of the central endocannabinoid system in energy balance regulation, the experiments described in this thesis were designed to investigate the role of the cannabinoid receptors in islet function. -- Initial studies indicated that mRNAs encoding the classical (CB1, CB2) and novel (GPRS5) cannabinoid receptors were expressed by mouse insulinoma (MIN6) (3-cells, and by mouse and human islets as well as enzymes involved in endocannabinoid biosynthesis (DAG-lipase) and degradation (FAAH and MGL). Receptor proteins of both CB1 and CB2 receptors were also found to be present in mouse and human islets by western blotting.

The Endocannabinoid System

The Endocannabinoid System Book
Author : Eric Murillo-Rodríguez
Publisher : Academic Press
Release : 2017-05-12
ISBN : 0128096675
Language : En, Es, Fr & De

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Book Description :

The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics. Provides an introduction to endocannabinoids in the central nervous system and an overview to their functions in the brain Presents information on neurobiological and cellular studies on the role of the cannabinoid signaling system and its implications in human diseases Includes well-written overviews of the basics of endocannabinoid system structure and function Contains well-illustrated material, with diagrams, charts, and tables Explores compelling case studies and their application to chapters written by experts

Cannabis and the Endocannabinoid System

Cannabis and the Endocannabinoid System Book
Author : Arnold Kuntz Ph D
Publisher : Unknown
Release : 2020-11-18
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The endocannabinoid system is a complex biological system in the human body. Medical researchers discovered it in the 1990s, but much is still unknown about how it works and its interactions. Today, experts know that it impacts several major processes, including appetite, sleep, mood, and memory, but there is much more yet to be discovered. The endocannabinoid system has three components: receptors, enzymes, and endocannabinoids. These parts function regardless of whether someone uses CBD or not.Here is an overview of each component: Receptors exist throughout the body and are a substance to which endocannabinoids bind; Enzymes appear in many forms, but only two types of enzymes break down endocannabinoids; and Endocannabinoids complement the body by keeping internal functions running smoothly. Understanding the effects of CBD involves examining the relationship between the receptors and endocannabinoids. There are two types of receptors: CB1 and CB2. CB1 receptors are primarily in the central nervous system and are responsible for governing coordination, movement, pain, appetite, memory, mood, and other functions. The CB2 receptors are in the peripheral nervous system, influencing pain, and inflammation.After the enzymes break down the cannabinoids, the endocannabinoids look to bind with receptors. Researchers believe that CBD does not directly attach itself to the receptor but influences it in some way. Activating these receptors is what allows for many of the health benefits that people associate with the compound. CBD can also influence non-cannabinoid receptors. CBD modulates the 5ht serotonin receptor, which can treat psychotic disorders. It can also affect the TRPV1 receptor, which is responsible for pain and inflammation

The Body Systems and the Endocannabinoid System ECS

The Body Systems and the Endocannabinoid System  ECS  Book
Author : Elise Bailey
Publisher : ECS Training Alliance Press
Release : 2020-02-16
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This exciting little book is a unique reference guide to the different body systems and the role that the endocannabinoid system (ECS) plays in each. With so many people using cannabinoids and terpenes it is important to understand how these things can influence body signaling. This book is easy to follow with beautiful visual diagrams and important scientific references. It is great for anyone wanting to learn how to better understand the role of the ECS in each body system. The information is intended to assist the reader to gain a basic understanding of the influential role the ECS plays in the body. It has been created for those that want to tap into the ECS using cannabinoids, terpenes, therapeutic grade essential oils, and vital nutrients. It is biology made easy and created for a consumer market. Created by Biologist Elise Bailey The ECS Training Alliance

Endocannabinoids Molecular Pharmacological Behavioral and Clinical Features

Endocannabinoids  Molecular  Pharmacological  Behavioral and Clinical Features Book
Author : Eric Murillo-Rodríguez,Emmanuel S. Onaivi,Nissar A. Darmani,Edward Wagner
Publisher : Bentham Science Publishers
Release : 2013-09-10
ISBN : 1608050289
Language : En, Es, Fr & De

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Book Description :

The endocannabinoid system comprises at least two G-protein-coupled receptors (the cannabinoid CB1 and CB2 receptors) activated by marijuana’s psychoactive principle ∆9-tetrahydrocannabinol (THC) and the endogenous ligands known as endocannabinoids. The apex of endocannabinoid research seems to have been reached with the clinical development, and also in some cases, the marketing, of synthetic or natural pharmaceuticals targeting this signalling system, which followed the understanding of the physiological and pathological role of endocannabinoids in several conditions, a role that was investigated first in rodent experimental models and then in humans. Endocannabinoids: Molecular, Pharmacological, Behavioral and Clinical Features is a monograph that presents interesting manuscripts selected by the editor on the subject. Chapters in this book include original research or reviews which report the relevance of the endocannabinoid system by describing the results of experimental evidence about the neurobiological role of the endocannabinoid system. The main topics include, but are not limited to: *The genetics of cannabinoid CB1 and CB2 receptors and their tissue distribution, their splicing variants and polymorphisms, and the possible implications of all this in determining different behaviours as well as various pathological conditions and the addiction to substances of abuse. *Pharmacological approaches describing the potential use in the central nervous system disorders of endocannabinoid-based drugs, such as cannabinoid receptor agonists and antagonists, inhibitors of endocannabinoid inactivation processes, and even plant cannabinoids other than THC and with a molecular mechanism of action. *The role of the endocannabinoid system in several neurological and neuropsychiatric conditions, such as epilepsy. The volume would be a great interest to neuropharmacologists, physiologists and biochemists who aim to learn about the endocannabinoid system in detail. Endocannabinoids: Molecular, Pharmacological, Behavioral and Clinical Features is a monograph that presents interesting manuscripts selected by the editor on the subject. Chapters in this book include original research or reviews which report the relevance of the endocannabinoid system by describing the results of experimental evidence about the neurobiological role of the endocannabinoid system. The main topics include, but are not limited to: *The genetics of cannabinoid CB1 and CB2 receptors and their tissue distribution, their splicing variants and polymorphisms, and the possible implications of all this in determining different behaviours as well as various pathological conditions and the addiction to substances of abuse. *Pharmacological approaches describing the potential use in the central nervous system disorders of endocannabinoid-based drugs, such as cannabinoid receptor agonists and antagonists, inhibitors of endocannabinoid inactivation processes, and even plant cannabinoids other than THC and with a molecular mechanism of action. *The role of the endocannabinoid system in several neurological and neuropsychiatric conditions, such as epilepsy. The volume would be a great interest to neuropharmacologists, physiologists and biochemists who aim to learn about the endocannabinoid system in detail. Endocannabinoids: Molecular, Pharmacological, Behavioral and Clinical Features is a monograph that presents interesting manuscripts selected by the editor on the subject. Chapters in this book include original research or reviews which report the relevance of the endocannabinoid system by describing the results of experimental evidence about the neurobiological role of the endocannabinoid system. The main topics include, but are not limited to: *The genetics of cannabinoid CB1 and CB2 receptors and their tissue distribution, their splicing variants and polymorphisms, and the possible implications of all this in determining different behaviours as well as various pathological conditions and the addiction to substances of abuse. *Pharmacological approaches describing the potential use in the central nervous system disorders of endocannabinoid-based drugs, such as cannabinoid receptor agonists and antagonists, inhibitors of endocannabinoid inactivation processes, and even plant cannabinoids other than THC and with a molecular mechanism of action. *The role of the endocannabinoid system in several neurological and neuropsychiatric conditions, such as epilepsy. The volume would be a great interest to neuropharmacologists, physiologists and biochemists who aim to learn about the endocannabinoid system in detail.

The Endocannabinoid System and Cannabis

The Endocannabinoid System and Cannabis Book
Author : Scott A. Johnson
Publisher : Scott A. Johnson Professional Writing Services LLC
Release : 2019-03-07
ISBN : 9780997548754
Language : En, Es, Fr & De

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Book Description :

Improve your physical, mental, and emotional health with the plant that is rewriting medicine as we know it. An ancient system designed to protect and heal, the endocannabinoid system is a group of receptors, molecules, and enzymes crucial to optimum health. The Endocannabinoid System and Cannabis: A Perfect Partnership for Self-Regulation and Healing explores how this ancient system works and how the cannabis plant provides molecules that can heal and regulate multiple body functions. Whether an experienced cannabis user or a first-time explorer, you'll be empowered to use cannabis to improve your health and feel better.

Cannabinoid Modulation of Emotion Memory and Motivation

Cannabinoid Modulation of Emotion  Memory  and Motivation Book
Author : Patrizia Campolongo,Liana Fattore
Publisher : Springer
Release : 2015-05-18
ISBN : 1493922947
Language : En, Es, Fr & De

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Book Description :

The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation. In the brain, endocannabinoids regulate ion channel activity and neurotransmitter release and thereby contribute to various aspects of brain function, including memory, reward and emotions. Their ability to modulate synaptic efficacy has a wide range of functional consequences and provides unique therapeutic possibilities. Unprecedented advances have been made in the understanding of the role of endocannabinoids in the regulation of the emotional brain over the past few years. However, a comprehensive book encompassing all these aspects is still lacking. The book will provide an overview of the role played by the endocannabinoid system in the regulation of emotional processes with particular emphasis on the modulation of memory and reward for emotionally arousing events and for the regulation of motivational aspects in cannabis use.

Cannabinoids as Therapeutics

Cannabinoids as Therapeutics Book
Author : Raphael Mechoulam
Publisher : Springer Science & Business Media
Release : 2006-03-30
ISBN : 376437358X
Language : En, Es, Fr & De

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Book Description :

Only a few years ago the endocannabinoid system was unknown. Today we are aware that endocannabinoids are involved in many of the functions of the mammalian body - in neuroprotection, appetite and suckling, pain, reproduction, anxiety, memory, bone formation etc. This volume presents an up-to-date picture of some of the major fields of endocannabinoid research. It summarizes the actions of the endocannabinoids on various physiological systems and opens new therapeutic windows to a large number of diseases. The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis. The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.

Plant Performance and the Endocannabinoid System

Plant  Performance and the Endocannabinoid System Book
Author : Doug Brown,Don McLaughlin
Publisher : Independently Published
Release : 2018-12-03
ISBN : 9781729495520
Language : En, Es, Fr & De

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Book Description :

How Hemp-CBD and Other Plants Boost Energy Reserves, Reduce Pain and Anxiety, Deepen Sleep, and Accelerate Recovery- What exactly is hemp-derived CBD?- Can CBD help me with pain and inflammation?- Can CBD help me with anxiety?- Can CBD help me with fatigue?- Is CBD safe to use?- Is CBD legal and can it be used in sports?- How do CBD and other plant extracts do all of this?If you are looking for answers to these questions, you've come to the right place.˃˃˃ Understand The BenefitsIn this book you will also learn how hemp-derived CBD and other potent botanicals fuel your body's endocannabinoid system in ways that help...- Boost energy at the cellular level- Enhance your mood and outlook- Increase your stamina- Better manage stress and anxiety- Help you sleep deeper- Accelerate your recovery˃˃˃ The health benefits tied to hemp-derived CBD and other potent plant extracts seem almost too good to be true: they reportedly help with gut health, brain injuries, chronic inflammation, sleep disorders, cramps, fatigue, stress, anxiety, and much more.In the world of sports, they're increasingly talked about among elite pro athletes and Olympians as an alternative to the highly addictive narcotics routinely dispensed for athletic injuries. So much so that the World Anti-Doping Agency (WADA) removed CBD from its prohibited substances list in January 2018, which applies to rules for the International Olympic Committee and the U.S. Anti-Doping Agency.˃˃˃ In Plants, Performance and the Endocannabinoid System21st Century Sports Medicine, join former trial lawyer turned wellness advocate, Don McLaughlin, and his co-author and journalist, Doug Brown, as they journey into the world of how CBD and other potent plants are fueling a grassroots movement in the sports world, one that has broader implications for anyone looking to boost not only health and well-being but also enhance performance and enjoyment in any area of life.Join Don and Doug's journey as they uncover the medical and physiological explanations for this movement, during which they get an inside view of the rigors and demands of elite athletics, from NFL gameday to skiing down the face of Alaskan glaciers. Read along as they connect with athletes who've competed at the highest levels in the NFL, ultra endurance trail running and extreme skiing. Here's some of what you'll learn: Buy Today and start reaping the benefits of hemp-derived CBD and other botanicals

Here There and Everywhere

Here  There and Everywhere Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Here There and Everywhere book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Wholistic Healing Guide to Cannabis

The Wholistic Healing Guide to Cannabis Book
Author : Tammi Sweet
Publisher : Storey Publishing
Release : 2020-07-07
ISBN : 1635861381
Language : En, Es, Fr & De

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Book Description :

Author Tammi Sweet combines her expertise in herbal medicine and neurobiology in this in-depth guide to understanding the science behind the effectiveness of cannabis medicine. In addition to exploring the chemistry of the whole cannabis plant, she explains the physiology of the human body’s endocannabinoid system and why and how it is affected by ingesting cannabis. Based on research and her own clinical experience, Sweet provides technique instructions for the best medicinal cannabis preparations and specific dosage recommendations for using these remedies to address a wide range of conditions, including stress, chronic pain, anxiety, PTSD, insomnia, and more. This volume offers a wealth of valuable information to healthcare professionals, practitioners of the healing arts, dispensary workers, and medical cannabis users who want to understand the science of cannabis and its effects on the whole body. This publication conforms to the EPUB Accessibility specification at WCAG 2.0 Level AA.

Cannabinoids and the Brain

Cannabinoids and the Brain Book
Author : Attila Köfalvi
Publisher : Springer Science & Business Media
Release : 2007-12-22
ISBN : 9780387743493
Language : En, Es, Fr & De

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Book Description :

Endocannabinoids have tremendous therapeutic potential. This book introduces readers to our current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential. Authors, experienced clinical investigators, present and analyze results of recent clinical trials as well as the development of new therapeutic strategies and medicines.

Road to Ananda

Road to Ananda Book
Author : Carl Germano
Publisher : Unknown
Release : 2018-10-31
ISBN : 9781732228283
Language : En, Es, Fr & De

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Book Description :

The role of the Endocannabinoid System (ECS) plays in the body. Revealing the and explaining the functional role of ECS has on our bodies as well as the way it can be used in the treatment of diseases. Further, the benefits of phytocannabinoids-CBD being one of many. It's important for us to come to terms with the fact our body makes cannabinoids similar to the cannabinoids found in Hemp/cannabis and the health of the ECS is paramount to our existence.

The Endocannabinoid System and Psychopathology

The Endocannabinoid System and Psychopathology Book
Author : Filippo Drago
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Endocannabinoid System and Psychopathology book written by Filippo Drago, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mitigate With Cannabis

Mitigate With Cannabis Book
Author : James Brown Ph D
Publisher : Unknown
Release : 2021-02-24
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

With cannabis approved in 11 states, the District of Columbia, and two U.S. territories; medical cannabis approved in at least 34 states; and hemp (very-low-THC cannabis) off the controlled substances list, millions now treat their ills with medical cannabis or non-intoxicating cannabinoids like CBD. But lots of them don't know why or how cannabis works in the body.Improve your physical, mental, and emotional health with the plant that is rewriting medicine as we know it. An ancient system designed to protect and heal, the endocannabinoid system is a group of receptors, molecules, and enzymes crucial to optimum health. The Endocannabinoid System and Cannabis: A Perfect Partnership for Self-Regulation and Healing explores how this ancient system works and how the cannabis plant provides molecules that can heal and regulate multiple body functions. Whether an experienced cannabis user or a first-time explorer, you'll be empowered to use cannabis to improve your health and feel better.