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The Double Helix

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The Double Helix

The Double Helix Book
Author : James D. Watson
Publisher : Simon and Schuster
Release : 2011-08-16
ISBN : 0743219171
Language : En, Es, Fr & De

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Book Description :

The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

Molecular Biology of the Gene

Molecular Biology of the Gene Book
Author : James D. Watson,Tania A. Baker,Stephen P. Bell
Publisher : Benjamin-Cummings Publishing Company
Release : 2014
ISBN : 9780321762436
Language : En, Es, Fr & De

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Book Description :

Now completely up-to-date with the latest research advances, the Seventh Edition retains the distinctive character of earlier editions. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.

The Annotated and Illustrated Double Helix

The Annotated and Illustrated Double Helix Book
Author : James D. Watson,Alexander Gann,Jan Witkowski
Publisher : Simon and Schuster
Release : 2012-11-06
ISBN : 1476715491
Language : En, Es, Fr & De

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Book Description :

In his 1968 memoir, The Double Helix (Readers Union, 1969), the brash young scientist James Watson chronicled the drama of the race to identify the structure of DNA, a discovery that would usher in the era of modern molecular biology. After half a century, the implications of the double helix keep rippling outward; the tools of molecular biology have forever transformed the life sciences and medicine. The Annotated and Illustrated Double Helix adds new richness to the account of the momentous events that led the charge.

Unravelling the Double Helix

Unravelling the Double Helix Book
Author : Gareth Williams
Publisher : Simon and Schuster
Release : 2019-10-01
ISBN : 1643132830
Language : En, Es, Fr & De

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Book Description :

Unraveling the Double Helix covers the most colorful period in the history of DNA, from the discovery of "nuclein" in the late 1860s to the publication of James Watson's The Double Helix in 1968. These hundred years included the establishment of the Nobel Prize, antibiotics, x-ray crystallography, the atom bomb and two devastating world wars—events which are strung along the thread of DNA like beads on a necklace. The story of DNA is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar. The elucidation of the double helix was one of the most brilliant gems of twentieth century science, but some of the scientists who paved the way have been airbrushed out of history. James Watson and Francis Crick solved a magnificent mystery, but Gareth Williams shows that their contribution was the last few pieces of a gigantic jigsaw puzzle assembled over several decades.The book is comprehensive in scope, covering the first century of the history of DNA in its entirety, including the eight decades that have been neglected by other authors. It also explores the personalities of the main players, the impact of their entanglement with DNA, and what unique qualities make great scientists tick.

The Path to the Double Helix

The Path to the Double Helix Book
Author : Robert Olby
Publisher : Courier Corporation
Release : 2013-05-13
ISBN : 0486166597
Language : En, Es, Fr & De

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Book Description :

Written by a noted historian of science, this in-depth account traces how Watson and Crick achieved one of science's most dramatic feats: their 1953 discovery of the molecular structure of DNA.

The Double Helix and the Law of Evidence

The Double Helix and the Law of Evidence Book
Author : David H. Kaye
Publisher : Harvard University Press
Release : 2010-05
ISBN : 9780674054110
Language : En, Es, Fr & De

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Book Description :

Bridging law, genetics, and statistics, this book is an authoritative history of the long and tortuous process by which DNA science has been integrated into the American legal system. In a history both scientifically sophisticated and comprehensible to the nonspecialist, David Kaye weaves together molecular biology, population genetics, the legal rules of evidence, and theories of statistical reasoning as he describes the struggles between prosecutors and defense counsel over the admissibility of genetic proof of identity. Combining scientific exposition with stories of criminal investigations, scientific and legal hubris, and distortions on all sides, Kaye shows how the adversary system exacerbated divisions among scientists, how lawyers and experts obfuscated some issues and clarified others, how probability and statistics were manipulated and misunderstood, and how the need to convince lay judges influenced the scientific research. Looking to the future, Kaye uses probability theory to clarify legal concepts of relevance and probative value, and describes alternatives to race-based DNA profile frequencies. Essential reading for lawyers, judges, and expert witnesses in DNA cases, The Double Helix and the Law of Evidence is an informative and provocative contribution to the interdisciplinary study of law and science.

Untangling the Double Helix

Untangling the Double Helix Book
Author : James C. Wang
Publisher :
Release : 2009
ISBN :
Language : En, Es, Fr & De

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Book Description :

The problem of unraveling two intertwined strands during the duplication of DNA was recognized shortly after the proposal of the DNA double helix structure in 1953. A group of enzymes called DNA topoisomerases solve this problem by breaking and rejoining DNA molecules in a controlled manner, thereby allowing strands to be passed through each other and thus untangled—not just during DNA replication, but also during many other basic cellular processes. Because of their intimate involvement in the workings of the cell, topoisomerases are also the logical targets of many antibiotics (including Cipro) and anticancer agents. This book, written by James Wang, the discoverer of the first topoisomerase and a leader in the field since, presents ten chapters covering the historical backdrop of the DNA entanglement problem and the discovery of the DNA topoisomerases, how DNA topoisomerases perform their magic in DNA replication, transcription, genetic recombination and chromosome condensation, and how they are targets of therapeutic agents. The book should appeal to readers from undergraduates upwards with interests in the biological and clinical aspects of topoisomerase function, or in the mathematics and physics of topology.

The Double Helix

The Double Helix Book
Author : James Watson
Publisher : Hachette UK
Release : 2012-09-06
ISBN : 1780225024
Language : En, Es, Fr & De

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Book Description :

The story of the most significant biological breakthrough of the century - the discovery of the structure of DNA. 'It is a strange model and embodies several unusual features. However, since DNA is an unusual substance, we are not hesitant in being bold' By elucidating the structure of DNA, the molecule underlying all life, Francis Crick and James Watson revolutionised biochemistry. At the time, Watson was only 24. His uncompromisingly honest account of those heady days lifts the lid on the real world of great scientists, with their very human faults and foibles, their petty rivalries and driving ambition. Above all, he captures the extraordinary excitement of their desperate efforts to beat their rivals at King's College to the solution to one of the great enigmas of the life sciences.