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The Comprehensive Sourcebook Of Bacterial Protein Toxins

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The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins Book
Author : Joseph E. Alouf,Daniel Ladant,Michel R. Popoff
Publisher : Academic Press
Release : 2015-05-29
ISBN : 0128005890
Language : En, Es, Fr & De

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Book Description :

The Comprehensive Sourcebook of Bacterial Protein Toxins 4th Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them. Focused chapters on toxin applications and common properties or general features of toxins.

The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins Book
Author : John H. Freer,Joseph E. Alouf
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition, provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the first edition (published in 1991), with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field. Key Features * Most up-to-date and comprehensive reference on the subject * Addresses recent achievements in basic and applied toxin research * Covers use of bacterial toxins in the development of new vaccines, immunodulators, and therapeutics against cancer and various neurological disorders * Written by internationally recognized scientists, including Randall Holmes, a recent candidate for presidency of the American Society for Microbiology

The Comprehensive Sourcebook of Bacterial Protein Toxins Fourth Edition

The Comprehensive Sourcebook of Bacterial Protein Toxins  Fourth Edition   Book
Author : Anonim
Publisher : Unknown
Release : 2021-10-26
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Comprehensive Sourcebook of Bacterial Protein Toxins Fourth Edition book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Sourcebook of Bacterial Protein Toxins

Sourcebook of Bacterial Protein Toxins Book
Author : Joseph E. Alouf,John H. Freer
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Written by an international team of leading scientists, this volume draws together a wealth of information on the structure, regulation, and activity of bacterial protein toxins. A comprehensive sourcebook on bacterial toxins, Sourcebook of Bacterial Protein Toxins is the first book designed to draw together current knowledge on these toxins. The 22 chapters of this book have been written by 44 internationally known specialists who have significantly contributed to the progress in the domains covered. This book will appeal to a wide readership, including microbiologists, biochemists, cell biologists, and physicians. It will also arouse the interest of students and scientists in other disciplines who see the power of these fascinating biological agents, either as exquisitely specific probes of cellular processes or as extremely potent agents of infectious disease.

The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins Book
Author : Joseph E. Alouf,Daniel Ladant,Michel R. Popoff
Publisher : Elsevier
Release : 2005-12-20
ISBN : 9780080456980
Language : En, Es, Fr & De

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Book Description :

This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology Includes the major toxins of both basic and clinical interest are described in depth Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology Evolutionary and functional aspects of bacterial toxins evaluated and summarized Toxin applications in cell biology presented Therapy (cancer therapy, dystonias) discussed Vaccines (native and genetically engineered vaccines) featured Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.

Pore Forming Toxins

Pore Forming Toxins Book
Author : Gisou van der Goot
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642565085
Language : En, Es, Fr & De

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Book Description :

Pore-forming toxins are virulence factors produced by a great variety of pathogenic bacteria ranging from the Gram-positive Staphylococcus aureus to the Gram-negative Helicobacter pylory. The recent studies reviewed in this volume describe the progress that has been made in dissecting the different steps of the mode of action of these proteins which generally include binding to specific cell surface receptors, oligomerization into ring like structures and membrane perforation.

Concepts in Bacterial Virulence

Concepts in Bacterial Virulence Book
Author : Wayne Russell,Heiko Herwald
Publisher : Karger Medical and Scientific Publishers
Release : 2005-01-01
ISBN : 3805577869
Language : En, Es, Fr & De

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Book Description :

Over the past few decades the increase in bacterial resistance has led to the search for novel antibacterial therapies and a better understanding of virulence mechanisms used by pathogens. It has been shown that the interplay between pathogenic bacteria and the host is complex and finely balanced. Successful pathogens can manipulate host homeostasis and normal cell functions using a variety of molecular strategies. This volume of the Karger book series Contributions to Microbiology summarizes some of the most important bacterial virulence mechanisms. Eminent scientists provide an update on recent findings in their fields. This state-of-the-art account will not only attract the interest of clinical and preclinical researchers, but will also be of great value to students with an interest in medicine, biology, chemistry, and infectious diseases.

Molecular Medical Microbiology

Molecular Medical Microbiology Book
Author : Yi-Wei Tang,Max Sussman,Dongyou Liu,Ian Poxton,Joseph Schwartzman
Publisher : Academic Press
Release : 2014-09-14
ISBN : 0123977630
Language : En, Es, Fr & De

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Book Description :

The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. The first comprehensive and accessible reference on molecular medical microbiology Full color presentation througout In-depth discussion of individual pathogenic bacteria in a system-oriented approach Includes a clinical overview for each major bacterial group Presents the latest information on vaccine development, molecular technology, and diagnostic technology More than 100 chapters covering all major groups of bacteria Written by an international panel of authors who are experts in their respective disciplines

Handbook on Clostridia

Handbook on Clostridia Book
Author : Peter Duerre
Publisher : CRC Press
Release : 2005-03-29
ISBN : 0203489810
Language : En, Es, Fr & De

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Book Description :

Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite growing scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments remains scattered in a variety of research ar

Cholesterol Binding and Cholesterol Transport Proteins

Cholesterol Binding and Cholesterol Transport Proteins  Book
Author : J. Robin Harris
Publisher : Springer Science & Business Media
Release : 2010-03-10
ISBN : 9789048186228
Language : En, Es, Fr & De

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Book Description :

Knowledge of cholesterol and its interaction with protein molecules is of fundamental importance in both animal and human biology. This book contains 22 chapters, dealing in depth with structural and functional aspects of the currently known and extremely diverse unrelated families of cholesterol-binding and cholesterol transport proteins. By drawing together this range of topics the Editor has attempted to correlate this broad field of study for the first time. Technical aspects are given considerable emphasis, particularly in relation cholesterol reporter molecules and to the isolation and study of membrane cholesterol- and sphingomyelin-rich "raft" domains. Cell biological, biochemical and clinical topics are included in this book, which serve to emphasize the acknowledged and important benefits to be gained from the study of cholesterol and cholesterol-binding proteins within the biomedical sciences and the involvement of cholesterol in several clinical disorders. It is hoped that by presenting this topic in this integrated manner that an appreciation of the fact that there is much more that needs to be taken into account, studied and understood than the widely discussed "bad and good cholesterol" associated, respectively, with the low- and high-density lipoproteins, LDL and HDL.

Bacterial Virulence

Bacterial Virulence Book
Author : Anthony William Maresso
Publisher : Springer Nature
Release : 2019-09-05
ISBN : 3030204642
Language : En, Es, Fr & De

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Book Description :

This textbook introduces in an engaging way the fundamentals of how pathogenic bacteria interact with, and are virulent within, the human host. To inspire and educate the next generation of microbe hunters, the author, Microbiologist and Scientist Anthony William Maresso, integrates the major findings of the field into a single, easy-to-understand volume emphasizing a molecular appreciation of the concepts underlying bacterial infectious diseases. The work explores such themes as the history of Microbiology, bacterial structure and physiology, bacterial toxins, secretion systems, and adhesins, the host immune system and its battle with bacteria, biofilms, sepsis, and technologies/techniques to the present day. Fully illustrated in concept and packed with idea-provoking challenges highlighting “out-of-the-box” thinking, the work moves beyond being just a review of the scientific literature intent on equipping the next generation of Microbiologists and their teachers with the knowledge to confront, and hopefully one day defeat, the insidious microbes which undermine human health. This textbook is a resource for undergraduate, graduate, and medical students, as well as other health-oriented learners, postdoctoral scholars, basic scientists, and professors intent on expanding their knowledge of bacterial infection and virulence mechanisms.

Human Microbiology

Human Microbiology Book
Author : Simon Hardy
Publisher : CRC Press
Release : 2003-08-27
ISBN : 9780203164402
Language : En, Es, Fr & De

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Book Description :

The widespread presence and activity of micro-organisms makes it impossible to study life sciences without some understanding of microorganisms. Human Microbiology provides a concise review of the biology of the three important groups of micro-organisms that infect humans: bacteria, viruses and fungi. Divided into two parts, it summarises the key features that characterise the physiology of microorganisms e.g. structure and function, growth and division, microbial death and the principles of taxonomy, and examines the common themes that are found in micro-organisms that cause disease in man, the transmission, epidemiology and pathogenicity of microbial diseases. With the overwhelming volume of information published on individual species of bacteria, viruses and fungi, Human Microbiology emphasises the important concepts and themes that occur in the organisms that are pathogenic to humans. The conventional approach to studying medical microbiology tends to result in exhaustive lists of microbes arranged by genus and their associated diseases. To promote understanding of the principles of medical microbiology and avoid memory lessons, the important concepts are discussed with reference to key examples.

Botulinum Neurotoxins for Head and Neck Disorders

Botulinum Neurotoxins for Head and Neck Disorders Book
Author : Andrew Blitzer,Brian E. Benson,Diana N. Kirke
Publisher : Thieme
Release : 2020-03-21
ISBN : 1684200962
Language : En, Es, Fr & De

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Book Description :

The most comprehensive, state-of-the-art guide available on the use of botulinum neurotoxin for head & neck disorders! Senior author Andrew Blitzer is an internationally renowned pioneer on the use of botulinum neurotoxin for functional disorders, with unparalleled expertise on this topic. Joined by esteemed co-editors Brian Benson and Diana Kirke, with multidisciplinary contributors, Botulinum Neurotoxin for Head and Neck Disorders Second Edition fills a gap in the medical literature. The unique textbook focuses on the use of botulinum neurotoxins for functional disorders of the head and neck, though with some aesthetic indications. The second edition reflects the latest advances and understanding of existing and emerging applications for botulinum neurotoxins, including new treatment paradigms, revised pharmacology, and an updated review of the literature in all chapters. Twenty superbly illustrated chapters cover the management of hyperfunctional, pain, and hypersecretory syndromes of the head and neck. Hyperfunctional motor disorders are discussed in chapters focused on blepharospasm, facial dystonia, Meige syndrome, oromandibular dystonia, spasmodic dysphonia (laryngeal dystonia), and cervical dystonia. Specific treatment approaches for pain are addressed in chapters on migraine and chronic daily tension headaches, temporomandibular disorders, and trigeminal neuralgia. The treatment of autonomic nervous system disorders is covered in chapters dedicated to Frey syndrome, facial hyperhydrosis, and sialorrhea. Key Features A 30-year review of spasmodic dysphonia data includes new insights encompassing comprehensive treatment, management and outcomes results, and neuropathophysiology A new chapter details the emerging role of botulinum neurotoxin to treat radiation-induced spasm and pain Updates on the management of palatal myoclonus, temporomandibular joint disorder, and sialorrhea An impressive compendium of professional injection videos, including a new video on sialorrhea and an updated migraine video Clinical pearls throughout the book focus on best practices, how to avoid pitfalls, and achieving the most optimal outcomes This is a must-have resource for otolaryngologists–head and neck surgeons, neurologists, dentists, pain specialists, physical medicine and rehabilitation specialists, and others health professionals who use botulinum neurotoxin to treat motor, sensory, and autonomic disorders of the head and neck region.

The Official Patient s Sourcebook on Bacterial Waterborne Diseases

The Official Patient s Sourcebook on Bacterial Waterborne Diseases Book
Author : Icon Health Publications
Publisher : Icon Group International Incorporated
Release : 2002
ISBN : 9780597835056
Language : En, Es, Fr & De

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Book Description :

This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to bacterial waterborne diseases (also Bacterial diarrhea; Food poisoning - Campylobacter enteritis; Infectious diarrhea - Campylobacter enteritis; Salmonellosis; Shigella gastroenteritis; Shigellosis), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on bacterial waterborne diseases. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms.

MACPF CDC Proteins Agents of Defence Attack and Invasion

MACPF CDC Proteins   Agents of Defence  Attack and Invasion Book
Author : Gregor Anderluh,Robert Gilbert
Publisher : Springer
Release : 2014-05-05
ISBN : 9401788812
Language : En, Es, Fr & De

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Book Description :

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.

Food Process Engineering and Quality Assurance

Food Process Engineering and Quality Assurance Book
Author : C.O. Mohan,Elizabeth Carvajal-Millan,C.N. Ravishankar,A. K. Haghi
Publisher : CRC Press
Release : 2018-02-28
ISBN : 1351869639
Language : En, Es, Fr & De

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Book Description :

This new book, Food Process Engineering and Quality Assurance, provides an abundance of valuable new research and studies in novel technologies used in food processing and quality assurance issues of food. The 750-page book gives a detailed technical and scientific background of various food processing technologies that are relevant to the industry. The food process related application of engineering technology involves interdisciplinary teamwork, which, in addition to the expertise of interdisciplinary engineers, draws on that of food technologists, microbiologists, chemists, mechanical engineers, biochemists, geneticists, and others. The processes and methods described in the book are applicable to many areas of the food industry, including drying, milling, extrusion, refrigeration, heat and mass transfer, membrane-based separation, concentration, centrifugation, fluid flow and blending, powder and bulk-solids mixing, pneumatic conveying, and process modeling, monitoring, and control. Food process engineering know-how can be credited with improving the conversion of raw foodstuffs into safe consumer products of the highest possible quality. This book looks at advanced materials and techniques used for, among other things, chemical and heat sterilization, advanced packaging, and monitoring and control, which are essential to the highly automated facilities for the high-throughput production of safe food products. With contributions from prominent scientists from around the world, this volume provides an abundance of valuable new research and studies on novel technologies used in food processing and quality assurance issues. It gives a detailed technical and scientific background of various food processing technologies that are relevant to the industry. Special emphasis is given to the processing of fish, candelilla, dairy, and bakery products. Rapid detection of pathogens and toxins and application of nanotechnology in ensuring food safety are also emphasized. Key features: • Presents recent research development with applications • Discusses new technology and processes in food process engineering • Provides several chapters on candelilla (which is frequently used as a food additive but can also be used in cosmetics, drugs, etc.), covering its characteristics, common uses, geographical distribution, and more

Scientific and Therapeutic Aspects of Botulinum Toxic

Scientific and Therapeutic Aspects of Botulinum Toxic Book
Author : Mitchell F. Brin,Mark Hallett,Joseph Jankovic
Publisher : Lippincott Williams & Wilkins
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Written by an international group of noted basic scientists and clinicians, this volume presents state-of-the-art information on the mechanisms of action, pharmacology, neurophysiological effects, and therapeutic uses of botulinum neurotoxins. A major portion of the book reviews recent clinical experience and clinical trials with botulinum toxin therapy for strabismus, dystonia, juvenile cerebral palsy, spasticity, hyperhidrosis, gastrointestinal and genitourinary disorders, headache, cosmetic facial conditions, and various disorders involving excessive muscle contraction or pain. Other chapters examine the immunology of botulinum toxins, the use of other chemodenervating agents, and the development of novel neurotoxin constructs.

ASM News

ASM News Book
Author : American Society for Microbiology
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download ASM News book written by American Society for Microbiology, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Casarett Doull s Toxicology The Basic Science of Poisons Seventh Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Seventh Edition Book
Author : Curtis Klaassen
Publisher : McGraw Hill Professional
Release : 2007-11-20
ISBN : 0071470514
Language : En, Es, Fr & De

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Book Description :

The most complete, trusted reference text covering the full span of medical toxicology A Doody's Core Title ESSENTIAL PURCHASE for 2011! "This reference stands alone as the basic text in the field of toxicology. This authoritative reference is written by many distinguished professionals in the field, and offers clear, concise descriptions of the key concepts in toxicology. It is extensive and complete, covering a broad range of topics in sufficient detail. Both as a reference and as an educational tool, this book exceeds its goal of serving as a reference for toxicologists, other scientists, and students of the discipline. 3 Stars."--Doody's Review Service Long established as the gold standard in the field, Casarett & Doull's Toxicology equips you with an unsurpassed understanding of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. The new seventh edition features is updated throughout and includes many new contributors and new content on chemical terrorism.

Text and Atlas of Wound Diagnosis and Treatment

Text and Atlas of Wound Diagnosis and Treatment Book
Author : Rose Hamm
Publisher : McGraw Hill Professional
Release : 2014-10-22
ISBN : 0071807241
Language : En, Es, Fr & De

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Book Description :

A UNIQUE COMBINATION TEXT AND FULL-COLOR ATLAS OF WOUND MANAGEMENT Text and Atlas of Wound Diagnosis and Treatment delivers outstanding visual guidance and clear, step-by-step instruction on caring for patients with wounds. Utilizing more than 700 full-color illustrations and clear, concise text, this unique learning text also includes complete discussion of evidence-based concepts of wound treatment. Text and Atlas of Wound Diagnosis and Treatment is logically divided into four sections: Integumentary Basics which covers fundamental topics such as anatomy and physiology of the integumentary system and acute and chronic wound healing Wound Diagnosis which discusses specific disorders such as vascular wounds, lymphedema, pressure ulcers, diabetes, burns, and more Wound Bed Preparation which details debridement and dressings Biophysical Technologies which includes electrical stimulation, negative pressure, pulsed lavage with suction, hyperbaric oxygen, ultraviolet, and low level laser therapy Text and Atlas of Wound Diagnosis and Treatment is enhanced by learning aids such as chapter objectives, NPTE-style review questions at the end of each chapter, and case studies which give real-world application to the principles and techniques discussed in the book. Entry-level students in all medical professions (doctors, podiatrists, physician assistants, nurses, physical therapists, and occupational therapists) will find this an essential text for understanding the multi-disciplinary approach to caring for patients with wounds.