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The Complex Interplay Between Gut Brain Gut Liver And Liver Brain Axes

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The Complex Interplay Between Gut Brain Gut Liver and Liver Brain Axes

The Complex Interplay Between Gut Brain  Gut Liver  and Liver Brain Axes Book
Author : Cristina Stasi
Publisher : Academic Press
Release : 2021-04-06
ISBN : 0128219289
Language : En, Es, Fr & De

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Book Description :

The Complex Interplay Between Gut–Brain, Gut–Liver, and Liver–Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut–brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut–liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver–brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome. Provides current and wide-ranging knowledge in the field of gastrointestinal, liver, and brain interactions. Resolves important clinical issues concerning gut, liver, and brain interactions. Demonstrates advances in the understanding of the pathophysiology of gastrointestinal and liver diseases.

Research Awards Index

Research Awards Index Book
Author : Anonim
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Awards Index book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Annual Report of the Director National Institute of Arthritis Diabetes and Digestive and Kidney Diseases

Annual Report of the Director  National Institute of Arthritis  Diabetes  and Digestive and Kidney Diseases Book
Author : National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases (U.S.)
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annual Report of the Director National Institute of Arthritis Diabetes and Digestive and Kidney Diseases book written by National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances in Food and Nutrition Research

Advances in Food and Nutrition Research Book
Author : Anonim
Publisher : Academic Press
Release : 2017-03-17
ISBN : 0128119179
Language : En, Es, Fr & De

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Book Description :

Advances in Food and Nutrition Research, Volume 81 provides updated knowledge on nutrients in foods and how to avoid deficiencies, paying special attention to the essential nutrients that should be present in the diet to reduce disease risk and optimize health. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution, and consumption. Contains contributions that have been carefully selected based on their vast experience and expertise on the subject Includes updated, in-depth, and critical discussions of available information, giving the reader a unique opportunity to learn Encompasses a broad view of the topics at hand

Primary Care for Women

Primary Care for Women Book
Author : Phyllis Carolyn Leppert,Fred M. Howard
Publisher : Lippincott Williams & Wilkins
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This reference is designed for clinicians who are increasingly responsible for primary care and need information on the diagnosis and management of non-gynaecologic disorders.

Human Microbiota in Health and Disease

Human Microbiota in Health and Disease Book
Author : Bryan Tungland
Publisher : Academic Press
Release : 2018-05-25
ISBN : 0128146508
Language : En, Es, Fr & De

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Book Description :

Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

Encyclopedia of Human Biology

Encyclopedia of Human Biology Book
Author : Renato Dulbecco
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Encyclopedia of Human Biology book written by Renato Dulbecco, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Hardy s Textbook of Surgery

Hardy s Textbook of Surgery Book
Author : James D. Hardy,John S. Kukora,Harvey I. Pass
Publisher : Lippincott Williams & Wilkins
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Hardy s Textbook of Surgery book written by James D. Hardy,John S. Kukora,Harvey I. Pass, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Management of Digestive and Liver Disorders in Infants and Children

Management of Digestive and Liver Disorders in Infants and Children Book
Author : Jean-Paul Buts
Publisher : Elsevier Science Limited
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Hardbound. This text has been organized to provide the reader with a comprehensive coverage of the physiological and biochemical processes essential for the understanding of diseases affecting the different parts of the gastrointestinal tract. It describes novel and recent concepts in the pathophysiology and management of common gastrointestinal, pancreatic and liver disorders encountered in infants and young children. Each chapter presents a basic clinical approach to the problem including pertinent investigations for confirming the diagnosis and for discussing the most appropiate therapy. Commonly used drugs are listed while references cited are the more recent rather than the classic ones. A vast number of related subjects are covered, each subject being presented by experts in that particular field.The book is divided into five parts: Disorders of the Oesophagus and Stomach; The Small Intestine and Stomach; The Exocrine Pancreas; and The Liver.T

Neurobiology of Stress Ulcers

Neurobiology of Stress Ulcers Book
Author : Daniel E. Hernandez,Gary B. Glavin
Publisher : Unknown
Release : 1990
ISBN : 9780897666039
Language : En, Es, Fr & De

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Book Description :

Download Neurobiology of Stress Ulcers book written by Daniel E. Hernandez,Gary B. Glavin, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Peripheral and Central Mechanisms in Irritable Bowel Syndrome

Peripheral and Central Mechanisms in Irritable Bowel Syndrome Book
Author : Olga Bednarska
Publisher : Linköping University Electronic Press
Release : 2019-05-07
ISBN : 9176850935
Language : En, Es, Fr & De

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Book Description :

Irritable bowel syndrome (IBS) is a chronic visceral pain disorder with female predominance, characterized by recurrent abdominal pain and disturbed bowel habits in the absence of an identifiable organic cause. This prevalent and debilitating disease, which accounts for a substantial economic and individual burden, lacks exact diagnostic tools and effective treatment, since its pathophysiology remains uncertain. The bidirectional and multilayered brain-gut axis is a well-established disease model, however, the interactions between central and peripheral mechanisms along the brain-gut axis remain incompletely understood. One of the welldescribed triggering factors, yet accounting for only a fraction of IBS prevalence, is bacterial gastroenteritis that affects mucosal barrier function. Altered gut microbiota composition as well as disturbed intestinal mucosal barrier function and its neuroimmune regulation have been reported in IBS, however, the impact of live bacteria, neither commensal nor pathogenic, on intestinal barrier has not been studied yet. Furthermore, abnormal central processing of visceral sensations and psychological factors such as maladaptive coping have previously been suggested as centrally-mediated pathophysiological mechanisms of importance in IBS. Brain imaging studies have demonstrated an imbalance in descending pain modulatory networks and alterations in brain regions associated with interoceptive awareness and pain processing and modulation, particularly in anterior insula (aINS), although biochemical changes putatively underlying these central alterations remain poorly understood. Most importantly, however, possible associations between these documented changes on central and peripheral levels, which may as complex interactions contribute to disease onset and chronification of symptoms, are widely unknown. This thesis aimed to investigate the peripheral and central mechanisms in women with IBS compared to female healthy controls (HC) and to explore possible mutual associations between these mechanisms. In Paper I, we studied paracellular permeability and passage of live bacteria, both commensal and pathogenic through colonic biopsies mounted in Ussing chambers. We explored the regulation of the mucosal barrier function by mast cells and the neuropeptide vasoactive intestinal polypeptide (VIP) as well as a correlation between mucosal permeability and gastrointestinal and psychological symptoms. We observed increased paracellular permeability and the passage of commensal and pathogenic live bacteria in patients with IBS compared with HC, which was diminished by blocking the VIP receptors as well as after stabilizing mast cells in both groups. Moreover, higher paracellular permeability was associated with less somatic and psychological symptoms in patients. In Paper II, we aimed to determine the association between colonic mucosa paracellular permeability and structural and resting state functional brain connectivity. We demonstrated different patterns of associations between mucosa permeability and functional and structural brain connectivity in IBS patients compared to HC. Specifically, lower paracellular permeability in IBS, similar to the levels detected in HC, was associated with more severe IBS symptoms and increased functional and structural connectivity between intrinsic brain resting state network and descending pain modulation brain regions. Our findings further suggested that this association between mucosa permeability and functional brain connectivity was mainly mediated by coping strategies. In Paper III, we investigated putative alterations in excitatory and inhibitory neurotransmission of aINS, as the brain’s key node of the salience network crucially involved in cognitive control, in IBS patients relative to HC and addressed possible connections with both symptoms and psychological factors. We found decreased concentrations of the excitatory neurotransmitter Glx in bilateral aINS in IBS patients compared to HC, while inhibitory neurotransmitter GABA+ levels were comparable. Further, we demonstrated hemisphere-specific associations between abdominal pain, coping and aINS excitatory neurotransmitter concentration. In conclusion, this thesis broadens the knowledge on peripheral and central mechanisms in IBS and presents novel findings that bring together the ends of brain-gut axis. Our results depict association between mucosal permeability, IBS symptoms and functional and structural connectivity engaging brain regions involved in emotion and pain modulation as well as underlying neurotransmitter alterations.

Short and Long Term Responses of the Gut brain Axis to Dietary Fat

Short and Long Term Responses of the Gut brain Axis to Dietary Fat Book
Author : Michael Jared Wright Donovan
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Short and Long Term Responses of the Gut brain Axis to Dietary Fat book written by Michael Jared Wright Donovan, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Appetite and Body Weight

Appetite and Body Weight Book
Author : Tim Kirkham,Steven J Cooper
Publisher : Elsevier
Release : 2011-04-28
ISBN : 9780080466460
Language : En, Es, Fr & De

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Book Description :

There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems. Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication. Provides an integrative view of the many systems involved in appetite how they interact to effect food intake (i.e. the brain, endocrine, gut, liver etc.) Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds

Journal of Experimental Biology

Journal of Experimental Biology Book
Author : Anonim
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of Experimental Biology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Textbook of Gastroenterology

Textbook of Gastroenterology Book
Author : Tadataka Yamada,David H. Alpers
Publisher : Lippincott Williams & Wilkins
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Textbook of Gastroenterology book written by Tadataka Yamada,David H. Alpers, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemical Abstracts

Chemical Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemical Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

METAL NEUROTOXICITY

METAL NEUROTOXICITY Book
Author : Kedar N. Prasad,Stephen Bondy
Publisher : CRC-Press
Release : 1987-12-31
ISBN : 9780849349416
Language : En, Es, Fr & De

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Book Description :

Download METAL NEUROTOXICITY book written by Kedar N. Prasad,Stephen Bondy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Encyclopedia of Hormones

Encyclopedia of Hormones Book
Author : Helen L. Henry,Anthony W. Norman
Publisher : Unknown
Release : 2003
ISBN : 9780123411068
Language : En, Es, Fr & De

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Book Description :

The Encyclopedia of Hormones is a comprehensive reference work on hormones in vertebrate, invertebrate, and plant systems. It covers all aspects of hormones: their chemical structure and biological synthesis the major physiological systems in which they operate the cellular and subcellular site of their action the nature of the signal transduction mechanisms used in the hormone's action and the biological consequences of an excess or deficiency of the hormone. Each contributor is an expert in his or her field and has been recruited by one of 14 Associate Editors. The 300 articles that comprise this encyclopedia are arranged alphabetically. Each entry begins with a glossary of key terms that are compiled into a complete glossary for the entire work. Additionally, each entry includes 10-15 recent references to provide the reader with an entry into the scientific literature. The Encyclopedia of Hormones is sure to be a valuable reference work for students and professional researchers interested in any aspect of the control of biological systems by hormonal signals. * The only source available with such comprehensive descriptions of hormones, their receptors, and their mechanisms of action * Full coverage including vertebrate, invertebrate, and plant hormones * Includes the chemistry, synthesis, secretion, and biological actions of hormones * Thorough coverage of signal transduction mechanisms as they relate to hormones * Contributions from over 500 experts in the study of hormones * Written to be accesssible to non-endocrinologists.

B A S I C

B A S I C  Book
Author : Anonim
Publisher : Unknown
Release : 1968
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download B A S I C book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.