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The Chemistry Of Heterocycles

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The Chemistry of Heterocycles

The Chemistry of Heterocycles Book
Author : Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap
Publisher : Elsevier
Release : 2019-06-05
ISBN : 0081011911
Language : En, Es, Fr & De

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Book Description :

Heterocycles are ubiquitously present in nature and occupy a unique place in organic chemistry as they are part of the DNA and haemoglobin that make life possible. The Chemistry of Heterocycles covers an introduction to the topic, followed by a chapter on the nomenclature of all classes of isolated, fused and polycyclic heterocycles. The third chapter delineates the highly strained three membered N,O and S containing aromatic and non-aromatic heterocycles with one and more than one similar and dissimilar heteroatom. The four-membered heterocycles are abundantly present in various natural and synthetic products of pharmacological importance. This chapter describes the natural abundance, synthesis, chemical reactivity, structural features and their medicinal importance. This class of compounds are present as sub-structures in penicillin and cytotoxic Taxol. Lastly, a chapter on the natural abundance, synthesis, chemical reactivity and pharmacological importance of 5-membered heterocycles with N,O,S heteroatom is covered. The chemistry of heterocycles with mixed heteroatom such as, N-S, N-O, N-S etc. is also described. Gives in-depth, clear information about various systems of nomenclature along with widely acceptable IUPAC system for naming various classes of heterocycles Provides complete information about natural occurrences, synthesis, chemical reactivity, pharmacological importance of heterocycles and their application in material science Highly relevant for graduate students and researchers, providing updated information about various isolated and fused N,O and,S containing heterocycles

The Chemistry of Heterocycles

The Chemistry of Heterocycles Book
Author : Theophil Eicher,Siegfried Hauptmann
Publisher : Wiley-VCH
Release : 2002-08-01
ISBN : 9783527308873
Language : En, Es, Fr & De

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Book Description :

The heterocycles are the largest group of organic compounds and this monograph represents a comprehensive survey of this vast field. The discussion is backed by numerous lucid diagrams while the extensive reaction schemes are supported by pertinent references. The text treats aromatic and nonaromatic heterocycles according to ring size under six defined headings for easy location and comparison, and also includes natural occurrence, synthetic aspects and applications in the chemical and pharmaceutical industries. An invaluable reference for advanced undergraduate and graduate students of chemistry and related subjects, this is equally an important aid to professional chemists and teachers of chemistry. Belongs on the shelf of every university library and in laboratories dealing with any aspect of heterocyclic chemistry.

The Chemistry of Heterocycles

The Chemistry of Heterocycles Book
Author : Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap
Publisher : Elsevier
Release : 2019-06-06
ISBN : 0128192119
Language : En, Es, Fr & De

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Book Description :

The Chemistry of Heterocycles: Chemistry of Six to Eight Membered N,O, S, P and Se Heterocycles details the chemistry, behavior and potential of these important structures. The book presents a practical guide to international nomenclature, including discussions of fused ring systems, heteroatoms with abnormal valences, and bridged, spiro and polycyclic heterocycles. Three membered heterocycles are then the focus, along with their thermodynamic properties and importance in natural products, medicines, materials, and their unique aspects, such as strain, basicity and reactivity. Additional chapters cover 100 key heterocycle structures, from Azetidines, Pyrroles and Pyridines, to Benzoxepines and Oxocanes. Final chapters explore cutting-edge advances in the development of phosphorus and selenium based heterocycles. Provides clear, detailed information on each heterocyclic group, including structural features, such as ring strain, basicity, synthesis and reactivity towards electrophilic and nucleophilic reagents Highlights the latest advances in the field, including phosphorous and selenium-based heterocycles supported by numerous illustrations Includes details of functionalized heterocycles used as synthons for the construction of various arenes and heteroarenes

Handbook of Heterocyclic Chemistry

Handbook of Heterocyclic Chemistry Book
Author : Alan R. Katritzky
Publisher : Elsevier
Release : 2017-01-31
ISBN : 1483293424
Language : En, Es, Fr & De

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Book Description :

Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

The Principles of Heterocyclic Chemistry

The Principles of Heterocyclic Chemistry Book
Author : Alan R. Katritzky,J. M. Lagowski
Publisher : Elsevier
Release : 2013-10-22
ISBN : 1483274519
Language : En, Es, Fr & De

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Book Description :

The Principles of Heterocyclic Chemistry presents a unified account of fundamental heterocyclic chemistry with the emphasis placed on the correlations between the methods of preparation and the properties of the various ring systems. This book opens with an introductory chapter that discusses fundamental concepts of the electronic theory of organic chemistry and the relationship of heterocyclic and carbocyclic aromatic compounds. This is followed by separate chapters on the chemistry of the six-membered ring compounds containing one or more heteroatoms, five-membered ring compounds, three- and four-membered rings, and the physical properties of representative heterocyclic compounds. Each chapter begins with introductory section that surveys the various ring types, gives the systems of nomenclature and numbering, and mentions a few important natural and synthetic compounds. Syntheses starting from aliphatic and carbocyclic compounds are then given. The preparation of one heterocyclic compound from another is considered as a reaction of the starting material. The reactions of aromatic and non-aromatic compounds are discussed separately. This book contains the essential heterocyclic chemistry required by an Undergraduate or Graduate student for his course-work, and it is hoped that it will be found stimulating by many a more senior teacher and researcher.

The Chemistry of Heterocycles

The Chemistry of Heterocycles Book
Author : Theophil Eicher,Siegfried Hauptmann,Andreas Speicher
Publisher : John Wiley & Sons
Release : 2013-02-26
ISBN : 3527669868
Language : En, Es, Fr & De

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Book Description :

This classical textbook in the best sense of the word is now completely revised, updated and with more than 40% new content. The approved ordering system according to the ring size of the heterocycles has been retained, while the important chapter on 'Problems and their Solutions' has been almost completely renewed by introduction of up-to-date scientific exercises, resulting in a great tool for self-testing and exams. There was maintained a chapter on nomenclature and a helpful index of name reactions. With approximately 1,000 new literature citations, this book remains a brilliant gateway to modern heterocyclic science for master and graduate students, as well as PhDs and researchers entering the field. 'If you want quick information about the basic (or acidic!) properties of a heterocycle, some interesting facts, or an assorted few ways of making it, this book provides a welcoming, accurate, and concise introduction.' Angewandte Chemie IE 'Eicher and Hauptmann provide an up to date introduction to the field for the advanced undergraduate and graduate students. ... The book is carefully produced to a very high standard.' European Journal of Medicinal Chemistry

Heterocycles in Life and Society

Heterocycles in Life and Society Book
Author : Alexander F. Pozharskii,Anatoly T. Soldatenkov,Alan R. Katritzky
Publisher : John Wiley & Sons
Release : 2011-03-31
ISBN : 111997013X
Language : En, Es, Fr & De

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Book Description :

Heterocycles in Life and Society is an introduction to the chemistry of heterocyclic compounds, focusing on their origin and occurrence in nature, biochemical significance and wide range of applications. Written in a readable and accessible style, the book takes a multidisciplinary approach to this extremely important area of organic chemistry. Topics covered include an introduction to the structure and properties of heterocycles; the key role of heterocycles in important life processes such as the transfer of hereditary information, how enzymes function, the storage and transport of bioenergy, and photosynthesis; applications of heterocycles in medicine, agriculture and industry; heterocycles in supramolecular chemistry; the origin of heterocycles on primordial Earth; and how heterocycles can help us solve 21st century challenges. For this second edition, Heterocycles in Life and Society has been completely revised and expanded, drawing on a decade of innovation in heterocyclic chemistry. The new edition includes discussions of the role of heterocycles in nanochemistry, green chemistry, combinatorial chemistry, molecular devices and sensors, and supramolecular chemistry. Impressive achievements include the creation of various molecular devices, the recording and storage of information, the preparation of new organic conductors, and new effective drugs and pesticides with heterocyclic structures. Much new light has been thrown on various life processes, while the chemistry of heterocycles has expanded to include new types of heterocyclic structures and reactions, and the use of heterocyclic molecules as ionic liquids and proton sponges. Heterocycles in Life and Society is an essential guide to this important field for students and researchers in chemistry, biochemistry, and drug discovery, and scientists at all levels wishing to expand their scientific horizon.

Synthesis of Heterocycles in Contemporary Medicinal Chemistry

Synthesis of Heterocycles in Contemporary Medicinal Chemistry Book
Author : Zdenko Časar
Publisher : Springer
Release : 2016-07-01
ISBN : 3319399179
Language : En, Es, Fr & De

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Book Description :

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Introduction to Heterocyclic Chemistry

Introduction to Heterocyclic Chemistry Book
Author : Peter A. Jacobi
Publisher : John Wiley & Sons
Release : 2018-08-08
ISBN : 1119417686
Language : En, Es, Fr & De

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Book Description :

A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.

s Triazines and Derivatives

s Triazines and Derivatives Book
Author : Edwin M. Smolin,Lorence Rapoport
Publisher : John Wiley & Sons
Release : 2009-09-15
ISBN : 047018812X
Language : En, Es, Fr & De

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Book Description :

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Organometallic Chemistry of Five Membered Heterocycles

Organometallic Chemistry of Five Membered Heterocycles Book
Author : Alexander Sadimenko
Publisher : Unknown
Release : 2019-10-25
ISBN : 0081028601
Language : En, Es, Fr & De

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Book Description :

Organometallic Chemistry of Five-Membered Heterocycles is a comprehensive source of information on the synthesis, coordination modes and reactivity of coordinated five-membered monoheterocycles and the organometallic complexes of their numerous derivatives, including chelating ligands, oligomers and macrocycles. Applications in modern materials chemistry are examined, including optical materials, catalysts, fuels, and more. An ideal reference for researchers working in organometallic, heterocyclic, materials chemistry, organic chemistry and catalysis, readers will find this book a comprehensive overview on the modern synthetic methods, possible coordination situations, trends in reactivity of the coordinated heteroaromatic ligands, and methods for construction of modern materials. Includes synthesis, structural features and coordination modes of five-membered heterocycles Features a comparative analysis of reactivity of uncoordinated and coordinated ligands Offers coverage of derivatives of fundamental ligands and examines trends in materials applications

Modern Heterocyclic Chemistry

Modern Heterocyclic Chemistry Book
Author : Julio Alvarez-Builla,Juan José Vaquero,José Barluenga
Publisher : John Wiley & Sons
Release : 2011
ISBN : 3527332014
Language : En, Es, Fr & De

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Book Description :

Download Modern Heterocyclic Chemistry book written by Julio Alvarez-Builla,Juan José Vaquero,José Barluenga, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Palladium in Heterocyclic Chemistry

Palladium in Heterocyclic Chemistry Book
Author : Jie Jack Li,Gordon W. Gribble
Publisher : Elsevier Science Limited
Release : 2007
ISBN : 9780080451169
Language : En, Es, Fr & De

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Book Description :

A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containing natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles.-

Heterocycles in Natural Product Synthesis

Heterocycles in Natural Product Synthesis Book
Author : Krishna C. Majumdar,Shital K. Chattopadhyay
Publisher : John Wiley & Sons
Release : 2011-06-15
ISBN : 3527634894
Language : En, Es, Fr & De

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Book Description :

Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.

Chemistry of Heterocyclic Compounds

Chemistry of Heterocyclic Compounds Book
Author : Rakesh Kumar Parashar
Publisher : CRC Press
Release : 2014-12-22
ISBN : 9781466517134
Language : En, Es, Fr & De

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Book Description :

This book discusses the structure, synthesis, and reactivity of heterocyclic compounds. It covers nomenclature, conformational aspects, aromatic stabilization and biological activity of heterocyclic compounds. The book also includes discussions of biochemical processes involving destruction of heterocyclic rings. It includes problem sets that help readers to understand and apply the principles of heterocyclic reactivity and synthesis. The inclusion of more advanced material and references make the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry, particularly in the pharmaceutical and agrochemical industries.

Name Reactions in Heterocyclic Chemistry

Name Reactions in Heterocyclic Chemistry Book
Author : Jie Jack Li
Publisher : John Wiley & Sons
Release : 2004-12-27
ISBN : 0471704148
Language : En, Es, Fr & De

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Book Description :

Covers important name reactions relevant to heterocyclic chemistry The field of heterocyclic chemistry has long presented a specialchallenge for chemists. Because of the enormous amount and varietyof information, it is often a difficult topic to cover forundergraduate and graduate chemistry students, even in simplifiedform. Yet the chemistry of heterocyclic compounds and methods fortheir synthesis form the bedrock of modern medicinal chemical andpharmaceutical research. Thus there is a great need for highquality, up-to-date, and authoritative books on heterocyclicsynthesis helpful to both the professional research chemist as wellas the advanced student. Name Reactions in Heterocyclic Chemistry provides aone-stop repository for this important field of organic chemistry.The primary topics include three- and four-membered heterocycles,five-membered heterocycles including indoles, furans, thiophenes,and oxazoles, six-membered heterocycles including quinolines,isoquinolines, and pyrimidines, and other heterocycles. Each name reaction is summarized in seven sections: Description Historical perspective Mechanism Variations and improvements Synthetic utility Experimental References Authored by a team of world-renowned contributors - some of whomhave discovered the very reactions they describe - NameReactions in Heterocyclic Chemistry represents astate-of-the-art resource for students and researchers alike.

Copper in N Heterocyclic Chemistry

Copper in N Heterocyclic Chemistry Book
Author : Ananya Srivastava
Publisher : Elsevier
Release : 2020-12-01
ISBN : 9780128212639
Language : En, Es, Fr & De

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Book Description :

Copper in N-Heterocyclic Chemistry provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, covering all recent developments in a way that is ideal for researchers and students working in the area of synthetic organic chemistry and medicinal chemistry. The book explores N-heterocyclic compounds as unique structural units in the development of natural products and pharmaceuticals, along with the remarkable progress made in the area of high atom economic strategies, and more recently, copper-catalyzed C-H activation and its applications in organic synthesis. Readers will find troubleshooting protocols, as well as the advantages and limitations of each method discussed. As copper catalysts show versatile chemical reactivity in many aspects, including their oxidation states 0-3 are accessible and their ability to facilitate bond formations due to their ability to serve as Lewis acids, oxidizing agents and catalysts, this book is an ideal resource on the topics explored. Discusses novel synthetic methods developed over the past decade for copper-catalyzed synthesis of N-heterocyclic compounds Covers the most recent methodologies adapted in synthetic chemistry for applications in natural products and pharmaceuticals Includes troubleshooting protocols, as well as the advantages and limitations of each method discussed in detail

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : Anonim
Publisher : New Age International
Release : 2022-08-13
ISBN : 9788122412123
Language : En, Es, Fr & De

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Book Description :

Download Heterocyclic Chemistry book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Pyrimidines

The Pyrimidines Book
Author : Desmond J. Brown
Publisher : John Wiley & Sons
Release : 2009-09-15
ISBN : 0470188251
Language : En, Es, Fr & De

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Book Description :

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Applications of Heterocycles in the Design of Drugs and Agricultural Products

Applications of Heterocycles in the Design of Drugs and Agricultural Products Book
Author : Anonim
Publisher : Academic Press
Release : 2021-06-18
ISBN : 0128201827
Language : En, Es, Fr & De

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Book Description :

Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Chapters in this updated volume cover Hydroxy azoles as carboxylic acid bioisosteres, Cyclic sulfoxides and sulfones in drug design, Thiazoles and topological control in drug design, Applications of fused pyrrolidine [3.3.0] heterocycles in drug design, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines. Because biology and organic chemistry increasingly intersect, the associated nomenclature is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and biological scientists Provides the latest, comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds