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The Chemistry Of Heterocycles

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The Chemistry of Heterocycles

The Chemistry of Heterocycles Book
Author : Theophil Eicher,Siegfried Hauptmann,Andreas Speicher
Publisher : John Wiley & Sons
Release : 2013-02-26
ISBN : 3527669868
Language : En, Es, Fr & De

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Book Description :

This classical textbook in the best sense of the word is now completely revised, updated and with more than 40% new content. The approved ordering system according to the ring size of the heterocycles has been retained, while the important chapter on 'Problems and their Solutions' has been almost completely renewed by introduction of up-to-date scientific exercises, resulting in a great tool for self-testing and exams. There was maintained a chapter on nomenclature and a helpful index of name reactions. With approximately 1,000 new literature citations, this book remains a brilliant gateway to modern heterocyclic science for master and graduate students, as well as PhDs and researchers entering the field. 'If you want quick information about the basic (or acidic!) properties of a heterocycle, some interesting facts, or an assorted few ways of making it, this book provides a welcoming, accurate, and concise introduction.' Angewandte Chemie IE 'Eicher and Hauptmann provide an up to date introduction to the field for the advanced undergraduate and graduate students. ... The book is carefully produced to a very high standard.' European Journal of Medicinal Chemistry

The Chemistry of Heterocycles

The Chemistry of Heterocycles Book
Author : Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap
Publisher : Elsevier
Release : 2019-06-06
ISBN : 0128192119
Language : En, Es, Fr & De

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Book Description :

The Chemistry of Heterocycles: Chemistry of Six to Eight Membered N,O, S, P and Se Heterocycles details the chemistry, behavior and potential of these important structures. The book presents a practical guide to international nomenclature, including discussions of fused ring systems, heteroatoms with abnormal valences, and bridged, spiro and polycyclic heterocycles. Three membered heterocycles are then the focus, along with their thermodynamic properties and importance in natural products, medicines, materials, and their unique aspects, such as strain, basicity and reactivity. Additional chapters cover 100 key heterocycle structures, from Azetidines, Pyrroles and Pyridines, to Benzoxepines and Oxocanes. Final chapters explore cutting-edge advances in the development of phosphorus and selenium based heterocycles. Provides clear, detailed information on each heterocyclic group, including structural features, such as ring strain, basicity, synthesis and reactivity towards electrophilic and nucleophilic reagents Highlights the latest advances in the field, including phosphorous and selenium-based heterocycles supported by numerous illustrations Includes details of functionalized heterocycles used as synthons for the construction of various arenes and heteroarenes

Name Reactions in Heterocyclic Chemistry

Name Reactions in Heterocyclic Chemistry Book
Author : Jie Jack Li
Publisher : John Wiley & Sons
Release : 2004-12-27
ISBN : 0471704148
Language : En, Es, Fr & De

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Book Description :

Covers important name reactions relevant to heterocyclic chemistry The field of heterocyclic chemistry has long presented a specialchallenge for chemists. Because of the enormous amount and varietyof information, it is often a difficult topic to cover forundergraduate and graduate chemistry students, even in simplifiedform. Yet the chemistry of heterocyclic compounds and methods fortheir synthesis form the bedrock of modern medicinal chemical andpharmaceutical research. Thus there is a great need for highquality, up-to-date, and authoritative books on heterocyclicsynthesis helpful to both the professional research chemist as wellas the advanced student. Name Reactions in Heterocyclic Chemistry provides aone-stop repository for this important field of organic chemistry.The primary topics include three- and four-membered heterocycles,five-membered heterocycles including indoles, furans, thiophenes,and oxazoles, six-membered heterocycles including quinolines,isoquinolines, and pyrimidines, and other heterocycles. Each name reaction is summarized in seven sections: Description Historical perspective Mechanism Variations and improvements Synthetic utility Experimental References Authored by a team of world-renowned contributors - some of whomhave discovered the very reactions they describe - NameReactions in Heterocyclic Chemistry represents astate-of-the-art resource for students and researchers alike.

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : John A. Joule,Keith Mills
Publisher : John Wiley & Sons
Release : 2013-05-28
ISBN : 1118681649
Language : En, Es, Fr & De

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Book Description :

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Handbook of Heterocyclic Chemistry

Handbook of Heterocyclic Chemistry Book
Author : Alan R. Katritzky,Christopher A. Ramsden,John A. Joule,Viktor V. Zhdankin
Publisher : Elsevier
Release : 2010-08-24
ISBN : 9780080958446
Language : En, Es, Fr & De

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Book Description :

Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts Features 35% new material to compliment the completely revised text

Modern Heterocyclic Chemistry

Modern Heterocyclic Chemistry Book
Author : Julio Alvarez-Builla,Juan José Vaquero,José Barluenga
Publisher : John Wiley & Sons
Release : 2011
ISBN : 3527332014
Language : En, Es, Fr & De

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Book Description :

Download Modern Heterocyclic Chemistry book written by Julio Alvarez-Builla,Juan José Vaquero,José Barluenga, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Introduction to Heterocyclic Chemistry

Introduction to Heterocyclic Chemistry Book
Author : Peter A. Jacobi
Publisher : John Wiley & Sons
Release : 2018-10-22
ISBN : 1119417597
Language : En, Es, Fr & De

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Book Description :

A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.

Fundamentals of Heterocyclic Chemistry

Fundamentals of Heterocyclic Chemistry Book
Author : Louis D. Quin,John A. Tyrell
Publisher : John Wiley & Sons
Release : 2010-07-08
ISBN : 9780470626535
Language : En, Es, Fr & De

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Book Description :

Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : Alvin Pugh
Publisher : Scientific e-Resources
Release : 2019-11-02
ISBN : 1839471964
Language : En, Es, Fr & De

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Book Description :

A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of these heterocycles. This text is a concise book that gives details of heterocyclic compounds. This book will also be useful to the students preparing for various competitive examinations. Much emphasis has been placed on chemical reactions and mechanisms of heterocyclic compounds. Each compound had been described in a clear and systematic manner. The subject-matter presented in each book, though concise, has adequate coverage of this subject; the important points wherever necessary have been highlighted; complex portion of the content has been interpreted in an easy to grasp manner; and long sequences of references of reactions have been summarized in short run flowcharts.

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : Radha R. Gupta,Mahendra Kumar,Vandana Gupta
Publisher : Springer Science & Business Media
Release : 2013-04-17
ISBN : 3662077574
Language : En, Es, Fr & De

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Book Description :

This advanced text-cum-reference book presents a comprehensive account of the syntheses, reactions, properties and applications of all the most significant classes of heterocyclic compounds. This second volume in the series is an essential tool not only for advanced undergraduates and graduates, but also for academic and industrial researchers in organic, medicinal, pharmaceutical, dye and agricultural chemistry.

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : Malcolm Sainsbury
Publisher : Royal Society of Chemistry
Release : 2001
ISBN : 9780854046522
Language : En, Es, Fr & De

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Book Description :

Tutorial Chemistry Texts is a series of short, single topic or modular texts, that focus on the fundamental areas of chemistry taught in undergraduate science courses. Each title provides a concise account of the basic principles of a given subject.

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : Thomas Lonsdale Gilchrist
Publisher : Prentice Hall
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book provides a unique overview of the subject. The first half of Heterocyclic Chemistry covers general properties of heterocyclic compounds and general methods for their preparation. This provides the basis for understanding the chemistry of indivudal ring systems that is described in later chapters. This edition has been completely revised to reflect the changes that have occurred in the field since the publication of the second edition in 1992.

Fluorine in Heterocyclic Chemistry Volume 2

Fluorine in Heterocyclic Chemistry Volume 2 Book
Author : Valentine Nenajdenko
Publisher : Springer
Release : 2014-07-08
ISBN : 3319044354
Language : En, Es, Fr & De

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Book Description :

This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry Book
Author : Alan R. Katritzky
Publisher : Academic Press
Release : 2013-10-04
ISBN : 0124079075
Language : En, Es, Fr & De

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Book Description :

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. One of great importance to organic chemists, polymer chemists and many biological scientists Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties

Heterocycles in Life and Society

Heterocycles in Life and Society Book
Author : Alexander F. Pozharskii,Anatoly T. Soldatenkov,Alan R. Katritzky
Publisher : John Wiley & Sons
Release : 2011-03-31
ISBN : 111997013X
Language : En, Es, Fr & De

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Book Description :

Heterocycles in Life and Society is an introduction to the chemistry of heterocyclic compounds, focusing on their origin and occurrence in nature, biochemical significance and wide range of applications. Written in a readable and accessible style, the book takes a multidisciplinary approach to this extremely important area of organic chemistry. Topics covered include an introduction to the structure and properties of heterocycles; the key role of heterocycles in important life processes such as the transfer of hereditary information, how enzymes function, the storage and transport of bioenergy, and photosynthesis; applications of heterocycles in medicine, agriculture and industry; heterocycles in supramolecular chemistry; the origin of heterocycles on primordial Earth; and how heterocycles can help us solve 21st century challenges. For this second edition, Heterocycles in Life and Society has been completely revised and expanded, drawing on a decade of innovation in heterocyclic chemistry. The new edition includes discussions of the role of heterocycles in nanochemistry, green chemistry, combinatorial chemistry, molecular devices and sensors, and supramolecular chemistry. Impressive achievements include the creation of various molecular devices, the recording and storage of information, the preparation of new organic conductors, and new effective drugs and pesticides with heterocyclic structures. Much new light has been thrown on various life processes, while the chemistry of heterocycles has expanded to include new types of heterocyclic structures and reactions, and the use of heterocyclic molecules as ionic liquids and proton sponges. Heterocycles in Life and Society is an essential guide to this important field for students and researchers in chemistry, biochemistry, and drug discovery, and scientists at all levels wishing to expand their scientific horizon.

Heterocyclic Chemistry

Heterocyclic Chemistry Book
Author : Anonim
Publisher : New Age International
Release : 2021-05-14
ISBN : 9788122412123
Language : En, Es, Fr & De

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Book Description :

Download Heterocyclic Chemistry book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Progress in Heterocyclic Chemistry

Progress in Heterocyclic Chemistry Book
Author : Gordon W. Gribble,John A. Joule
Publisher : Newnes
Release : 2012
ISBN : 0080968074
Language : En, Es, Fr & De

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Book Description :

"Progress in Heterocyclic Chemistry" (PHC) an ongoing reference work on heterocyclic chemistry is published with the active involvement of The International Society of Heterocyclic Chemistry (ISHC) whose aim is to promote heterocyclic chemistry, in particular by serving as the primary sponsoring agency for the ISHC-Congress, a large biannual meeting attracting up to a thousand participants. Recognized as the premiere review of heterocyclic chemistry Contributions from leading researchers in the field Systematic survey of the important 2011 heterocyclic chemistry literature

The Principles of Heterocyclic Chemistry

The Principles of Heterocyclic Chemistry Book
Author : Alan R. Katritzky,J. M. Lagowski
Publisher : Elsevier
Release : 2013-10-22
ISBN : 1483274519
Language : En, Es, Fr & De

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Book Description :

The Principles of Heterocyclic Chemistry presents a unified account of fundamental heterocyclic chemistry with the emphasis placed on the correlations between the methods of preparation and the properties of the various ring systems. This book opens with an introductory chapter that discusses fundamental concepts of the electronic theory of organic chemistry and the relationship of heterocyclic and carbocyclic aromatic compounds. This is followed by separate chapters on the chemistry of the six-membered ring compounds containing one or more heteroatoms, five-membered ring compounds, three- and four-membered rings, and the physical properties of representative heterocyclic compounds. Each chapter begins with introductory section that surveys the various ring types, gives the systems of nomenclature and numbering, and mentions a few important natural and synthetic compounds. Syntheses starting from aliphatic and carbocyclic compounds are then given. The preparation of one heterocyclic compound from another is considered as a reaction of the starting material. The reactions of aromatic and non-aromatic compounds are discussed separately. This book contains the essential heterocyclic chemistry required by an Undergraduate or Graduate student for his course-work, and it is hoped that it will be found stimulating by many a more senior teacher and researcher.

Heterocyclic Chemistry in the 21st Century A Tribute to Alan Katritzky

Heterocyclic Chemistry in the 21st Century  A Tribute to Alan Katritzky Book
Author : Anonim
Publisher : Academic Press
Release : 2017-01-03
ISBN : 0128120703
Language : En, Es, Fr & De

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Book Description :

Advances in Heterocyclic Chemistry: Heterocyclic Chemistry in the 21st Century: A Tribute to Alan Katritzky is the definitive series in the field—one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Written by established, global authorities in the field, this comprehensive review combines descriptive synthetic chemistry and mechanistic insights to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists, and many biological scientists Provides the latest comprehensive reviews as written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Palladium in Heterocyclic Chemistry

Palladium in Heterocyclic Chemistry Book
Author : Jie Jack Li,Gordon W. Gribble
Publisher : Gulf Professional Publishing
Release : 2006-10-30
ISBN : 9780080914411
Language : En, Es, Fr & De

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Book Description :

Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially. These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of Palladium in Heterocyclic Chemistry is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 1. Palladium chemistry of heterocycles has its "idiosyncrasies" stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containing natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles. Many heterocycle-containing natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field. It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting field. Contains the most up-to-date developments in this fast-moving field Includes 3 new chapters Contains material from selected well-respected authors on heterocyclic chemistry