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Targeted

Targeted Book
Author : Stephen Hunter
Publisher : Atria/Emily Bestler Books
Release : 2022-01-18
ISBN : 9781982169794
Language : En, Es, Fr & De

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Book Description :

Pulitzer Prize winner and New York Times bestselling author Stephen Hunter returns with a taut, white-knuckled thriller featuring master sniper Bob Lee Swagger as he protects a group of political hostages during a perilous standoff and once again proves his title of “true American literary icon” (Mark Greaney, author of Mission Critical). After his successful takedown of a dangerous terrorist, Bob Lee Swagger learns that no good deed goes unpunished. Summoned to court by the United States Congress, Swagger is accused of reckless endangerment by a hardheaded anti-gun congresswoman. But what begins as political posturing soon turns deadly when the auditorium where the committee is being held is attacked. Swagger, the congresswoman, and numerous bystanders and reporters are taken hostage by a group of violent operatives. Soon, the very people who had accused him are depending on him to save their lives. Trapped in the auditorium and still struggling with injuries from his last assignment, Swagger must rely on his instincts, his shooting skills, and the help of a mysterious rogue sniper on the outside in order to ensure that everyone makes it out alive. A heart-pounding and crackling action-packed novel, Targeted proves that Stephen Hunter is “a true master at the pinnacle of his craft. No one does it better” (Jack Carr, Former Navy SEAL Sniper and author of The Terminal List).

Targeted

Targeted Book
Author : Brittany Kaiser
Publisher : HarperCollins
Release : 2019-10-22
ISBN : 0062965808
Language : En, Es, Fr & De

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Book Description :

In this explosive memoir, a political consultant and technology whistleblower reveals the disturbing truth about the multi-billion-dollar data industry, revealing to the public how companies are getting richer using our personal information and exposing how Cambridge Analytica exploited weaknesses in privacy laws to help elect Donald Trump—and how this could easily happen again in the 2020 presidential election. When Brittany Kaiser joined Cambridge Analytica—the UK-based political consulting firm funded by conservative billionaire and Donald Trump patron Robert Mercer—she was an idealistic young professional working on her fourth degree in human rights law and international relations. A veteran of Barack Obama’s 2008 campaign, Kaiser’s goal was to utilize data for humanitarian purposes, most notably to prevent genocide and human rights abuses. But her experience inside Cambridge Analytica opened her eyes to the tremendous risks that this unregulated industry poses to privacy and democracy. Targeted is Kaiser’s eyewitness chronicle of the dramatic and disturbing story of the rise and fall of Cambridge Analytica. She reveals to the public how Facebook’s lax policies and lack of sufficient national laws allowed voters to be manipulated in both Britain and the United States, where personal data was weaponized to spread fake news and racist messaging during the Brexit vote and the 2016 election. But the damage isn’t done Kaiser warns; the 2020 election can be compromised as well if we continue to do nothing. In the aftermath of the U.S. election, as she became aware of the horrifying reality of what Cambridge Analytica had done in support of Donald Trump, Kaiser made the difficult choice to expose the truth. Risking her career, relationships, and personal safety, she told authorities about the data industry’s unethical business practices, eventually testifying before Parliament about the company’s Brexit efforts and helping Special Counsel Robert Mueller’s investigation into Russian interference in the 2016 election, alongside at least 10 other international investigations. Packed with never-before-publicly-told stories and insights, Targeted goes inside the secretive meetings with Trump campaign personnel and details the promises Cambridge Analytica made to win. Throughout, Kaiser makes the case for regulation, arguing that legal oversight of the data industry is not only justifiable but essential to ensuring the long-term safety of our democracy. Targeted includes 20-30 photos.

An Employment targeted Economic Program for Kenya

An Employment targeted Economic Program for Kenya Book
Author : Robert Pollin,Mwangi wa Gĩthĩnji,Mwangi Wa Githinji,James Heintz
Publisher : Edward Elgar Pub
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Contents: Brief Highlights of Major Proposals Summary of Major Findings and Proposals 1. Introduction 2. Employment Conditions and Living Standards 3. Profile of Non-agricultural Household Enterprises 4. Labor Costs, Labor Market Institutions and Employment Expansion 5. The Rural Sector: Institutional Reform for Development 6. Investing in Roads and Water Infrastructure 7. Monetary Policy, Inflation Control, and Interest Rates 8. Exchange Rate Policy and Foreign Trade 9. Restructuring Kenya's Financial System 10. Fiscal Policy: How to Pay for New Pro-employment Initiatives 11. A Restatement of Goals and Strategies Appendix 1: Earnings Function for Household Enterprises Appendix 2: Supply Shock Inflation Appendix 3: Exchange Rate Overvaluation Model Acronyms Bibliography Index

Creation of Novel Targeted Antimicrobial Peptides

Creation of Novel Targeted Antimicrobial Peptides Book
Author : Randal Hojem Eckert
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Creation of Novel Targeted Antimicrobial Peptides book written by Randal Hojem Eckert, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Targeted Killing in International Law

Targeted Killing in International Law Book
Author : Nils Melzer
Publisher : Oxford University Press on Demand
Release : 2008-05-29
ISBN : 0199533164
Language : En, Es, Fr & De

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Book Description :

A comprehensive analysis into the lawfulness of state-sponsored targeted killings under international human rights and humanitarian law, this book examines treaties, custom and general principles of law to determine the normative paradigms which govern the intentional use of lethal force against selected individuals in law enforcement and the conduct of hostilities. Through an exhaustive analysis of recent state practice and jurisprudence, the book establishes when targeted killing may be considered lawful, and what legal restraints are imposed on the practice in times of war and peace.

Targeted Killings

Targeted Killings Book
Author : Claire Finkelstein,Jens David Ohlin,Andrew Altman
Publisher : OUP Oxford
Release : 2012-03-01
ISBN : 0191625906
Language : En, Es, Fr & De

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Book Description :

The war on terror is remaking conventional warfare. The protracted battle against a non-state organization, the demise of the confinement of hostilities to an identifiable battlefield, the extensive involvement of civilian combatants, and the development of new and more precise military technologies have all conspired to require a rethinking of the law and morality of war. Just war theory, as traditionally articulated, seems ill-suited to justify many of the practices of the war on terror. The raid against Osama Bin Laden's Pakistani compound was the highest profile example of this strategy, but the issues raised by this technique cast a far broader net: every week the U.S. military and CIA launch remotely piloted drones to track suspected terrorists in hopes of launching a missile strike against them. In addition to the public condemnation that these attacks have generated in some countries, the legal and moral basis for the use of this technique is problematic. Is the U.S. government correct that nations attacked by terrorists have the right to respond in self-defense by targeting specific terrorists for summary killing? Is there a limit to who can legitimately be placed on the list? There is also widespread disagreement about whether suspected terrorists should be considered combatants subject to the risk of lawful killing under the laws of war or civilians protected by international humanitarian law. Complicating the moral and legal calculus is the fact that innocent bystanders are often killed or injured in these attacks. This book addresses these issues. Featuring chapters by an unrivalled set of experts, it discusses all aspects of targeted killing, making it unmissable reading for anyone interested in the implications of this practice.

Targeted Killing

Targeted Killing Book
Author : Markus Gunneflo
Publisher : Cambridge University Press
Release : 2016-05-12
ISBN : 1316552845
Language : En, Es, Fr & De

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Book Description :

Looking beyond the events of the second intifada and 9/11, this book reveals how targeted killing is intimately embedded in both Israeli and US statecraft, and in the problematic relationship between sovereign authority and lawful violence underpinning the modern state system. It details the legal and political issues raised in targeted killing as it has emerged in practice, including questions of domestic constitutional authority, the use of force in international law, the law of belligerent occupation, the law of targeting and human rights law. The distinctive nature of Israeli and US targeted killing is analysed in terms of the compulsion of legality characteristic of the liberal constitutional state, a compulsion that demands the ability to distinguish between legal 'targeted killing' and extra-legal 'political assassination'. The effect is a highly legalized framework for the extraterritorial killing of designated terrorists that may significantly affect the international law of force.

Targeted Violence

Targeted Violence Book
Author : Glenn P. McGovern
Publisher : CRC Press
Release : 2011-06-03
ISBN : 1439857393
Language : En, Es, Fr & De

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Book Description :

Drawn from case examples of incidents from around the world, Targeted Violence: A Statistical and Tactical Analysis of Assassinations, Contract Killings, and Kidnappings is the most complete resource of information on the attack methodologies, tactics used, and groups responsible for targeted killings and kidnappings. The author, a former SWAT and JTTF team member—whose experience includes providing protection to diplomats, high-ranking military personnel, prosecutors, and organized crime informants—presents a wealth of global statistics on assassinations, contract killings, and kidnappings that have occurred from 1950 to the present. Leaving no stone unturned, the book breaks down the various incidents of targeted violence by region, country, month, day of the week, and time of day. It reports on likely locations for each type of attack, success rates, who is likely to initiate the attacks, and who they are most likely to target. The book’s easy-to-follow format allows readers, experienced or not in personal protective work, to determine the types of attacks known to have occurred in any region. This complete reference includes 35 case studies that examine attacks on motorcades and pedestrians dating back to 1973—highlighting the lessons to be learned from each example. It analyzes the modus operandi of individual assailants and groups in order to determine commonalities between targeted victims and why certain groups tend to target a specific type of individual. The text concludes with a chapter on victimology. Just like anyone, assassins and hit men fall into routines and can become creatures of habit. By studying and understanding the collection of historical information contained in these pages, security, military, and law enforcement professionals responsible for providing protection will be better prepared to identify potential threats and develop the tactics needed to thwart such attacks.

Targeted Drug Strategies for Cancer and Inflammation

Targeted Drug Strategies for Cancer and Inflammation Book
Author : Ann L. Jackman,Christopher P. Leamon
Publisher : Springer Science & Business Media
Release : 2011-05-05
ISBN : 9781441984173
Language : En, Es, Fr & De

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Book Description :

Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made within the last decade include (i) the approval of pemetrexed for the treatment of lung cancer and mesothelioma, and (ii) the demonstration that cell membrane-anchored folate receptors (FR) are exploitable for cancer and inflammatory disease management. FRs are not widely distributed in normal tissues, except on some luminal surfaces; however, they are accessible to systemically administered agents when expressed on many cancers as well as on activated macrophages involved in various inflammatory diseases. High affinity folate-radioisotope conjugates have been developed for imaging pathogenic FR-positive diseases, including cancer. Since the FR transports folates via a low capacity but high affinity endocytic pathway, a variety of FR-targeted antifolate drugs and folate conjugates bearing a wide range of payloads (including cytotoxic drugs) are currently being developed which exploit this property. The FR is also being utilized in immunotherapy approaches for the treatment of overexpressing cancers.

Targeted

Targeted Book
Author : Katie Reus
Publisher : Penguin
Release : 2013-10-01
ISBN : 110161773X
Language : En, Es, Fr & De

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Book Description :

Hidden in plain sight… Former Marine sniper and current NSA agent Jack Stone has a new face to go with his new identity. But he still has the same tortured memories—which include the woman he let get away years ago, when they were teenagers. Now his new assignment in Miami will put him so close to the woman he’s never been able to forget, he could reach out and touch her—if only she weren’t under suspicion. When Sophie Moreno uncovers evidence linking the medical supply company she works for with arms smuggling—and worse—she doesn’t know who to turn to. After a shocking betrayal, she realizes the only person she can trust is a mysterious new person in the company—a man with hauntingly familiar eyes. As Sophie questions her intense attraction to this man and Jack struggles not to blow his cover, the two of them must race against the clock to stop terrorists from killing scores of people—starting with them. FIRST IN A NEW SERIES!

Targeted Therapies for Glioblastoma A Critical Appraisal

Targeted Therapies for Glioblastoma  A Critical Appraisal Book
Author : Shiv K. Gupta,Sani H. Kizilbash,Thierry M. Muanza
Publisher : Frontiers Media SA
Release : 2020-01-22
ISBN : 2889633535
Language : En, Es, Fr & De

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Book Description :

Download Targeted Therapies for Glioblastoma A Critical Appraisal book written by Shiv K. Gupta,Sani H. Kizilbash,Thierry M. Muanza, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Debating Targeted Killing

Debating Targeted Killing Book
Author : Tamar Meisels,Jeremy Waldron
Publisher : Oxford University Press
Release : 2020-05-14
ISBN : 0190906936
Language : En, Es, Fr & De

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Book Description :

Known terrorists are often targeted for death by the governments of Israel and the United States. Several thousand have been killed by drones or by operatives on the ground in the last twenty years. Is this form of killing justified, when hundreds or thousands of lives are possibly at risk at the hands of a known terrorist? Is there anything about it that should disturb us? Ethically-sound and practical answers to these questions are more difficult to come by than it might seem. Renowned political theorists Jeremy Waldron and Tamar Meisels here defend two competing positions on the legitimacy of targeted killing as used in counterterrorism strategy in this riveting and essential for-and-against book. The volume begins with a joint introduction, briefly setting out the terms of discussion, and presenting a short historical overview of the practice: what targeted killing is, and how it has been used in which conflicts and by whom. It then hones in on killings themselves and the element of targeting. The authors tackle difficult and infinitely complex subjects, for example the similarities and differences between targeted killing of terrorists and ordinary killings in combat, and they ask whether targeted killing can be regarded as a law enforcement strategy, or as a hybrid between combat and law enforcement. They compare the practice of targeted killing with assassination and the use of death squads. And they consider the likelihood that targeted killing has been or will be abused against insurgents, criminals, or political opponents. Meisels analyzes the assassination by Israeli operatives of nuclear scientists working for regimes hostile to Israel. Meisels and Waldron carefully consider whether this sort of killing can ever be justified in terms of the danger it, in theory, averts. The conclusions drawn are at once as surprising as they are insightful, cautioning us against a world in which targeted killing is the norm as it proliferates rapidly. This is essential reading not only for students of political and war theory and military personnel, but for anyone interested in or concerned by the future of targeted killing.

Drones and the Ethics of Targeted Killing

Drones and the Ethics of Targeted Killing Book
Author : Kenneth R. Himes
Publisher : Rowman & Littlefield
Release : 2015-09-03
ISBN : 1442231572
Language : En, Es, Fr & De

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Book Description :

Drones have become an essential part of U.S. national security strategy, but most Americans know little about how they are used, and we receive conflicting reports about their outcomes. In Drones and the Ethics of Targeted Killing, ethicist Kenneth R. Himes provides not only an overview of the role of drones in national security but also an important exploration of the ethical implications of drone warfare—from the impact on terrorist organizations and civilians to how piloting drones shapes soldiers. Targeted killings have played a role in politics from ancient times through today, so the ethical challenges around how to protect against threats are not new. Himes leads readers through the ethics of targeted killings in history from ancient times to the contemporary Israeli-Palestinian conflict, then looks specifically at the new issues raised through the use of drones. This book is a powerful look at a pressing topic today.

Cancer Targeted Drug Delivery

Cancer Targeted Drug Delivery Book
Author : You Han Bae,Randall J. Mrsny,Kinam Park
Publisher : Springer Science & Business Media
Release : 2013-08-31
ISBN : 1461478766
Language : En, Es, Fr & De

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Book Description :

This book was conceived from a simple question as to why cancer is so difficult to treat. Ultimately we want to find ways to cure cancers, but that may be an elusive dream at least with the technologies we have now and expect to have in the near future. This leads the question of whether it is possible to improve current cancer treatment methods, especially from the perspective of enhancing targeted drug delivery to tumors. This volume is designed to provide information related to the difficulties in treating cancers through targeted drug delivery, our current understanding of cancer biology, and potential technologies that might be used to achieve enhanced drug delivery to tumors. An ideal drug delivery system for treating cancers would maximize the therapeutic efficacy with minimal side effects in clinical applications. The seemingly improved anticancer efficacy of the current nanoparticle-based formulations needs to be viewed from the context of very poor success rates for translation to human applications. The results of in vitro cell culture models and small animal in vivo experiments have not been extrapolated to clinical applications. Finding the reasons for the lack of successful translation is required if we are to discover approaches to substantially extend the survival time of cancer patients, and hopefully identify cures. Cancer Targeted Drug Delivery: Elusive Dream describes some answers of achieving the so far elusive dream of treating cancers like other chronic diseases with therapies that focus using improved drug delivery systems designed to better align with the unique biological and physiological properties of cancer.

Advances in Targeted Cancer Therapy

Advances in Targeted Cancer Therapy Book
Author : Richard M. Schultz
Publisher : Springer Science & Business Media
Release : 2006-01-24
ISBN : 3764374144
Language : En, Es, Fr & De

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Book Description :

There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully these new targeted therapies will significantly increase efficacy and lack the devastating and troublesome side effects elicited by cytotoxic chemotherapy. This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed. This volume should be of broad general interest to researchers and clinicians involved in cancer therapy as well as other scientists interested in current strategies for cancer treatment.

HUD s Targeted Tandem Apartment Building Subsidy Program

HUD s Targeted Tandem Apartment Building Subsidy Program Book
Author : United States. Congress. House. Committee on Government Operations. Manpower and Housing Subcommittee
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download HUD s Targeted Tandem Apartment Building Subsidy Program book written by United States. Congress. House. Committee on Government Operations. Manpower and Housing Subcommittee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Targeted Molecular Imaging

Targeted Molecular Imaging Book
Author : Michael J. Welch,William C. Eckelman
Publisher : Taylor & Francis
Release : 2012-02-24
ISBN : 1439841969
Language : En, Es, Fr & De

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Book Description :

Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.

Nanotechnology Based Targeted Drug Delivery Systems for Brain Tumors

Nanotechnology Based Targeted Drug Delivery Systems for Brain Tumors Book
Author : Prashant Kesharwani,Umesh Gupta
Publisher : Academic Press
Release : 2018-04-20
ISBN : 0128122498
Language : En, Es, Fr & De

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Book Description :

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors

Targeted Phonics More Consonants Blends and Digraphs Teachers Guide

Targeted Phonics  More Consonants  Blends  and Digraphs  Teachers Guide Book
Author : Anonim
Publisher : Teacher Created Materials
Release : 2012-04-15
ISBN : 9781433339905
Language : En, Es, Fr & De

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Book Description :

Download Targeted Phonics More Consonants Blends and Digraphs Teachers Guide book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

User Perception of Targeted Ads in Online Social Networks

User Perception of Targeted Ads in Online Social Networks Book
Author : Timo Beck
Publisher : GRIN Verlag
Release : 2011-03
ISBN : 3640836944
Language : En, Es, Fr & De

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Book Description :

Doctoral Thesis / Dissertation from the year 2010 in the subject Business economics - Marketing, Corporate Communication, CRM, Market Research, Social Media, grade: 1,0, University of St Andrews (School of Management), language: English, abstract: Owing to the phenomenal growth of online social networks and the resulting interest of marketers in this new medium, this thesis investigates user perception of targeted advertisements on Facebook, the world's largest and fastest growing social network. Based on a critical literature review, results of previous research studies, and expert interviews with social media practitioners, the author develops a conceptual framework consisting of seven factors that are theorised to impact on how users perceive personalised ads in a social network environment. This framework is partially verified on an empirical basis by means of an online survey among 97 Facebook users. The results provide novel and useful insights into user perception of targeted ads on Facebook that could be used as guidelines for practitioners and as a starting point for further studies.