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Tantalizing Therapeutics In Bronchopulmonary Dysplasia

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Tantalizing Therapeutics in Bronchopulmonary Dysplasia

Tantalizing Therapeutics in Bronchopulmonary Dysplasia Book
Author : Vineet Bhandari
Publisher : Academic Press
Release : 2020-06-02
ISBN : 0128189916
Language : En, Es, Fr & De

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Book Description :

Tantalizing Therapeutics in Bronchopulmonary Dysplasia is a concise reference that provides an overview of emerging concepts in the understanding of lung development and injury from a molecular and cellular point-of-view, including exciting pathways that are paving the way for new options to prevent or treat Bronchopulmonary Dysplasia (BPD). The book's chapters are written by experts who are at the forefront of BPD research. Coverage includes chapters on exosomes, stem cells and miRs, as well as a section on new discoveries in BPD research with translational potential. This is a must-have reference for researchers, physicians and trainees working on BPD, lung developmental biology, and more. Includes discussions on which aspects of the bench research in Bronchopulmonary Dysplasia are the most promising areas Offers insights into the latest research being conducted that could potentially move to the bassinet (in the NICU) Contains evidence-based summaries and informed opinions about existing therapies

Targeted Molecular Imaging in Oncology

Targeted Molecular Imaging in Oncology Book
Author : E. Edmund Kim,David J. Yang
Publisher : Springer Science & Business Media
Release : 2001
ISBN : 9780387950280
Language : En, Es, Fr & De

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Book Description :

Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.

Hypoxia and the Circulation

Hypoxia and the Circulation Book
Author : Robert Roach,Peter D. Wagner,Peter Hackett
Publisher : Springer Science & Business Media
Release : 2008-01-08
ISBN : 0387754342
Language : En, Es, Fr & De

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Book Description :

Just one of a series of volumes on differing aspects of hypoxia, this authoritative text focuses on cutting-edge research at the interface of hypoxia and biomedicine. Hypoxia – or lack of oxygen – is a constant threat to the human body and its vital organs, one that can take its toll in a number of situations. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. The International Hypoxia Symposia was founded to enable scientists, clinicians, physiologists, immunologists, mountaineers and other interested individuals to share their experiences of the situations associated with the lack of oxygen and the adaptations that allow us to survive.

The Newborn Lung

The Newborn Lung Book
Author : Eduardo Bancalari
Publisher : Elsevier Health Sciences
Release : 2018-06-19
ISBN : 0323568750
Language : En, Es, Fr & De

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Book Description :

Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with The Newborn Lung, 3rd Edition. The most current clinical information throughout, including key management strategies that may reduce some of the chronic sequelae of neonatal respiratory failure. New content on the role of microbiome in lung injury and lung development. Current coverage of non-invasive respiratory support, perinatal events and their influence on lung development and injury, cell-based lung therapy, automation of respiratory support, and oxygenation targeting in preterm infants. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology Neurology The Newborn Lung

Pediatric Practice Gastroenterology

Pediatric Practice Gastroenterology Book
Author : Warren Bishop
Publisher : McGraw Hill Professional
Release : 2010-10-06
ISBN : 9780071639644
Language : En, Es, Fr & De

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Book Description :

Complete how-to guidance on managing gastrointestinal diseases and disorders in children In full color! Part of the Pediatric Practice series, Pediatric Practice: Gastroenterology is a unique source of clinically relevant information on the diagnosis and treatment of children with gastrointestinal symptoms and disorders. The care of the patient forms the core of this full-color resource, which also provides perspectives on epidemiology, pathophysiology, and diagnosis that every pediatrician, pediatric resident, gastroenterologist, and pediatric nurse needs to know. Expert authors in each subject area provide detailed, yet concise overviews of important disorders of the esophagus, stomach, intestine, pancreas, and liver. You will also find discussion of common symptoms, their differential diagnosis, and how they should be evaluated and treated along with an introduction to the use of diagnostic modalities such as radiology, nuclear medicine, and endoscopy. A listing of relevant, recent articles appears at the end of each chapter allowing you to expand your exploration of a given topic. The Pediatric Practice series simplifies the care of pediatric patients by delivering: Tips that tell you what you must know—and what you must do—at every stage of care Diagnostic and treatment algorithms Signs/Symptoms and Differential Diagnosis boxes “When to Refer” boxes, which examine all the relevant clinical considerations Diagnostic Tests—with a realistic emphasis on the right tests to order Medical Treatment coverage that includes drugs, dosages, and administration in an easy-to-read tabular format Convenient icons and a templated chapter design Numerous clinical color photos and didactic diagrams Logical section organization, with consistent headings among chapters covering similar topics Introductory sections that provide an update on recent research that informs clinical practice Full-color throughout

Magnetic Resonance Elastography

Magnetic Resonance Elastography Book
Author : Sudhakar K. Venkatesh,Richard L. Ehman
Publisher : Springer
Release : 2014-10-01
ISBN : 1493915754
Language : En, Es, Fr & De

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Book Description :

The first book to cover the groundbreaking development and clinical applications of Magnetic Resonance Elastography, this book is essential for all practitioners interested in this revolutionary diagnostic modality. The book is divided into three sections. The first covers the history of MRE. The second covers technique and clinical applications of MRE in the liver with respect to fibrosis, liver masses, and other diseases. Case descriptions are presented to give the reader a hands-on approach. The final section presents the techniques, sequence and preliminary results of applications in other areas of the body including muscle, brain, lung, heart, and breast.

Diseases of the Newborn

Diseases of the Newborn Book
Author : Alexander J. Schaffer,Mary Ellen Avery
Publisher : W.B. Saunders Company
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Over 9000 English-language entries to medical terminology, with etymology given in Japanese and English. Entries include word in English; part of speech; Greek, Latin, or other roots; and elements of word.

Marcus and Feldman s Osteoporosis

Marcus and Feldman s Osteoporosis Book
Author : David W. Dempster,Jane A. Cauley,Mary L. Bouxsein,Felicia Cosman
Publisher : Academic Press
Release : 2020-10-08
ISBN : 0128130741
Language : En, Es, Fr & De

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Book Description :

Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development. Summarizes the latest research in bone biology and translational applications in a range of new therapeutic agents, including essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, parathyroid hormone, and new therapeutic agents Recognizes the critical importance of new signaling pathways for bone health, including Wnt, OPG and RANK, of interest to both researchers who study bone biology and clinicians who treat osteoporosis Offers new insights into osteoporosis associated with menopause, pre-menopause, chronic kidney disease, diabetes, HIV and other immune disorders

The Nucleosome

The Nucleosome Book
Author : A.P. Wolffe
Publisher : Elsevier
Release : 1996-01-08
ISBN : 9780080537849
Language : En, Es, Fr & De

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Book Description :

This is the first in a series of volumes concerning the properties of the eukaryotic nucleus. Contributions from several of the most active laboratories are brought together to present a focused overview of a selected aspect of nuclear structure and function.

Diagnostic and Therapeutic Antibodies

Diagnostic and Therapeutic Antibodies Book
Author : Andrew J. T. George,Catherine E. Urch
Publisher : Springer Science & Business Media
Release : 2000
ISBN : 1592590764
Language : En, Es, Fr & De

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Book Description :

Download Diagnostic and Therapeutic Antibodies book written by Andrew J. T. George,Catherine E. Urch, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Kendig and Chernick s Disorders of the Respiratory Tract in Children E Book

Kendig and Chernick s Disorders of the Respiratory Tract in Children E Book Book
Author : Robert W. Wilmott,Thomas F. Boat,Andrew Bush,Victor Chernick,Robin R Deterding,Felix Ratjen
Publisher : Elsevier Health Sciences
Release : 2012-02-25
ISBN : 1455740500
Language : En, Es, Fr & De

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Book Description :

Kendig, Chernick’s Disorders of the Respiratory Tract in Children is the definitive medical reference book to help you confront critical challenges using the latest knowledge and techniques. You’ll get the state-of-the-art answers you need to offer the best care to young patients. Tackle the toughest challenges and improve patient outcomes with coverage of all the common and rare respiratory problems found in newborns and children worldwide. Get a solid foundation of knowledge to better understand and treat your patients through coverage of the latest basic science and its relevance to clinical problems. Get comprehensive, authoritative coverage on today’s hot topics, such as interstitial lung disease, respiratory disorders in the newborn, congenital lung disease, swine flu, genetic testing for disease and the human genome, inflammatory cytokines in the lung, new radiologic techniques, diagnostic imaging of the respiratory tract, and pulmonary function tests. Learn from the experts with contributions from 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, anesthesiology, otolaryngology, allergy, and surgery.

Hematology Immunology and Infectious Disease

Hematology  Immunology  and Infectious Disease Book
Author : Robin Kjerstin Ohls,Mervin C. Yoder,Richard Alan Polin
Publisher : Saunders
Release : 2008
ISBN : 9781416031581
Language : En, Es, Fr & De

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Book Description :

Hematology, Immunology and Infectious Disease, a volume in Dr. Polin's Neonatology: Questions and Controversies Series, offers expert authority on some of the toughest challenges you face in your practice. This medical reference book will help you provide better evidence-based care and improve patient outcomes with research on the latest advances. Reconsider how you handle difficult practice issues with coverage that addresses these topics head on and offers opinions from the leading experts in the field, supported by evidence whenever possible. Find information quickly and easily with a consistent chapter organization. Get the most authoritative advice available from world-class neonatologists who have the inside track on new trends and developments in neonatal care. Purchase each volume individually, or get the entire 6-volume set, which includes online access that allows you to search across all titles! Stay current in practice with coverage on issues on the pathogenesis, diagnosis, and treatment of neonatal thrombocytopenia, diagnostic technologies in the management of congenital infection, and much more. Access the fully searchable text online at www.expertconsult.com.

Transporters in Drug Discovery and Development

Transporters in Drug Discovery and Development Book
Author : Yurong Lai
Publisher : Woodhead Publishing
Release : 2014-08-22
ISBN : 190881828X
Language : En, Es, Fr & De

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Book Description :

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments. A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development Balanced coverage of molecular biology aspects and functional outcomes State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity

Atomistic Simulation of Materials

Atomistic Simulation of Materials Book
Author : David J. Srolovitz,V. Vitek
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1468457039
Language : En, Es, Fr & De

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Book Description :

This book contains proceedings of an international symposium on Atomistic th Simulation of Materials: Beyond Pair Potentials which was held in Chicago from the 25 th to 30 of September 1988, in conjunction with the ASM World Materials Congress. This symposium was financially supported by the Energy Conversion and Utilization Technology Program of the U. S Department of Energy and by the Air Force Office of Scientific Research. A total of fifty four talks were presented of which twenty one were invited. Atomistic simulations are now common in materials research. Such simulations are currently used to determine the structural and thermodynamic properties of crystalline solids, glasses and liquids. They are of particular importance in studies of crystal defects, interfaces and surfaces since their structures and behavior playa dominant role in most materials properties. The utility of atomistic simulations lies in their ability to provide information on those length scales where continuum theory breaks down and instead complex many body problems have to be solved to understand atomic level structures and processes.

Assisted Ventilation of the Neonate

Assisted Ventilation of the Neonate Book
Author : Edward H. Karotkin
Publisher : W B Saunders Company
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Assisted Ventilation of the Neonate book written by Edward H. Karotkin, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Avery s Diseases of the Newborn

Avery s Diseases of the Newborn Book
Author : H. William Taeusch,Roberta A. Ballard
Publisher : W B Saunders Company
Release : 1998
ISBN : 9780721657516
Language : En, Es, Fr & De

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Book Description :

This definitive resource in perinatology and neonatology is now completely revised and updated to incorporate the latest advances in the field. Maintains a clinical focus and provides guidelines for precise diagnosis and effective treatment. Also includes hundreds of case histories to illustrate management. This edition contains new neuromuscular, cardiovascular, genetic, and pulmonary information plus ethics of neonatology. Reorganized and supplemented, the perinatal section includes maternal-fetal medicine and fetal neonatal surgery. Features over 700 illustrations! Spanish version also available, ISBN: 84-8174-433-6

Hepatocyte Transplantation

Hepatocyte Transplantation Book
Author : S. Gupta,Peter L.M. Jansen,J. Klempnauer,M.P. Manns
Publisher : Springer Science & Business Media
Release : 2002-09-30
ISBN : 9780792387763
Language : En, Es, Fr & De

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Book Description :

In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application? This book is the proceedings of the Falk Symposium No. 126 on `Hepatocyte Transplantation' (Progress in Gastroenterology and Hepatology Part III) held in Hannover, Germany, October 2-3, 2001, and is a forum for basic research, but also for questions concerning clinical applications in the field of hepatocyte transplantation.

Chesley s Hypertensive Disorders in Pregnancy

Chesley s Hypertensive Disorders in Pregnancy Book
Author : Robert N. Taylor,James M. Roberts,F. Gary Cunningham,Marshall D. Lindheimer
Publisher : Elsevier
Release : 2014-08-28
ISBN : 0124079458
Language : En, Es, Fr & De

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Book Description :

Chesley’s Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial. The fourth edition of Chesley’s Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia. Features new chapters focusing on recent discoveries in areas such as fetal programming, genomics/proteomics, and angiogenesis Includes extensive updates to chapters on epidemiology, etiological considerations, pathophysiology, prediction, prevention, and management Discusses the emerging roles of metabolic syndrome and obesity and the increasing incidence of preeclampsia Each section overseen by one of the editors; each chapter co-authored by one of the editors, ensuring coherence throughout book

The Wondrous Story of Anesthesia

The Wondrous Story of Anesthesia Book
Author : Edmond I Eger II,Lawrence J. Saidman,Rod N. Westhorpe
Publisher : Springer Science & Business Media
Release : 2013-09-14
ISBN : 1461484413
Language : En, Es, Fr & De

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Book Description :

Edited and written by an international "who's who" of more than 100 authors, including anesthesiologists, nurse anesthetists, bench scientists, a surgeon, and representatives of industry, this text provides a comprehensive history of anesthesia, unique in its focus on the people and events that shaped the specialty around the world, particularly during the past 70 years when anesthesia emerged from empiricism and developed into a science-based practice.

Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies Book
Author : Ramasamy Paulmurugan,Tarik F. Massoud
Publisher : Academic Press
Release : 2021-06-25
ISBN : 0128215682
Language : En, Es, Fr & De

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Book Description :

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance