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Systems Neuroscience In Depression

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Systems Neuroscience in Depression

Systems Neuroscience in Depression Book
Author : Thomas Frodl
Publisher : Academic Press
Release : 2016-09-01
ISBN : 0128026286
Language : En, Es, Fr & De

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Book Description :

Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. Knowledge covering the whole life span from early to later life Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience Understanding the neurobiology of major depressive disorder Integrating stress and environmental factors with molecular underpinnings More than 25 illustrations and tables

Neurobiology of Depression

Neurobiology of Depression Book
Author : Francisco Lopez-Munoz,Cecilio Alamo
Publisher : CRC Press
Release : 2011-09-09
ISBN : 1439838496
Language : En, Es, Fr & De

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Book Description :

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology, and pharmacology, Neurobiology of Depression discusses the nature of the central nervous system circuits responsible for the modifications of neuronal functioning that lead to depression. The book begins by discussing animal, neurophysiological, and neuropsychological models of depression as well as neural foundations. It explores genetic factors that contribute to depression and describes the effect of monoaminergic systems in the central nervous system. Next, the book profiles the rise of psychopharmacology in the treatment of depression and the research into serotonin and monoamine reuptake inhibitors. It examines the role of the glutamatergic, endocannabinoid, and opioid systems in the pathophysiology of mood disorders, as well as the effect of biological rhythms on the human body. Later chapters review the role of CRF-related ligands, CRF receptors, HPA axis activity, and glucocorticoid receptors in the regulation of the stress response and depression. They also describe cytokine modulation of molecular mechanisms. They examine the role of neuropeptide Y, nitric oxide, beta-arrestins, BDNF, and phosphodiesterases, and discuss the use of tachykinin antagonists in treatment. Finally, they analyze the neurobiological basis for the development of new antidepressant agents. Exploring myriad aspects of a disease that plagues a large percentage of the population worldwide, this volume captures the state of the science of this debilitating disorder, facilitating further research and discovery.

The Oxford Handbook of Clinical Child and Adolescent Psychology

The Oxford Handbook of Clinical Child and Adolescent Psychology Book
Author : Thomas H. Ollendick,Susan W. White,Bradley A. White
Publisher : Oxford Library of Psychology
Release : 2018-12-07
ISBN : 0190634847
Language : En, Es, Fr & De

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Book Description :

At the founding in 1896 of the first psychological clinic dedicated to children and adolescents, the study of the psychological treatment of young people lagged behind that of adults, and the basic psychopathology underlying mental disorders in this population was largely ignored. Since those early days, the field has evolved steadily and, in recent years, exponentially. The Oxford Handbook of Clinical Child and Adolescent Psychology is a state-of-the-science volume providing comprehensive coverage of the psychological problems and disorders of childhood. International in scope and penned by the discipline's most eminent scientists and practitioners, the handbook begins with a section on conceptual and empirical issues, followed by exceptional content on specific psychiatric disorders such as intellectual disability, externalizing and internalizing disorders, communication disorders, schizophrenia and bipolar disorder, personality disorders, and many more. The third section offers chapters on special problems in childhood and adolescence, including divorce, the incarceration of parents, suicide and non-suicidal self-injury, bullying, and medical illness. A fourth section covers delivery of clinical services in diverse settings, such as schools and prisons, and the handbook concludes with several chapters on emerging trends and future directions for the field. Conceptually rich and evidence-based, this handbook is an essential resource for students, practitioners, and researchers, providing a cutting-edge compendium of the latest theoretical and empirical developments by leaders of the discipline.

Resting state brain activity Implications for systems neuroscience

Resting state brain activity  Implications for systems neuroscience Book
Author : Vinod Menon,Lucina Q. Uddin
Publisher : Frontiers E-books
Release : 2021-04-19
ISBN : 2889190412
Language : En, Es, Fr & De

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Book Description :

Research on resting state brain activity using fMRI offers a novel approach for understanding brain organization at the systems level. Resting state fMRI examines spatial synchronization of intrinsic fluctuations in blood-oxygenation-level-dependent (BOLD) signals arising from neuronal and synaptic activity that is present in the absence of overt cognitive information processing. Since the discovery of coherent spontaneous fluctuations within the somatomotor system (Biswal, et al. 1995), a growing number of studies have shown that many of the brain areas engaged during various cognitive tasks also form coherent large-scale brain networks that can be readily identified using resting state fMRI. These studies are beginning to provide new insights into the functional architecture of the human brain. This Research Topic will synthesize current knowledge about resting state brain activity and discuss their implications for understanding brain function and dysfunction from a systems neuroscience perspective. This topic will also provide perspectives on important conceptual and methodological questions that the field needs to address in the next years. In addition to invited reviews and perspectives, we solicit research articles on theoretical, experimental and clinical questions related to the nature, origins and functions of resting state brain activity.

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research Book
Author : Anonim
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biomedical Index to PHS supported Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Systems Neuroscience

Systems Neuroscience Book
Author : University of Massachusetts (Amherst campus). Center for Systems Neuroscience
Publisher : Unknown
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Systems Neuroscience book written by University of Massachusetts (Amherst campus). Center for Systems Neuroscience, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Inflammation and Immunity in Depression

Inflammation and Immunity in Depression Book
Author : Bernhard Baune
Publisher : Academic Press
Release : 2018-05-23
ISBN : 0128110740
Language : En, Es, Fr & De

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Book Description :

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

Traumatic Brain Injury as a Systems Neuroscience Problem

Traumatic Brain Injury as a Systems Neuroscience Problem Book
Author : H. Isaac Chen,John F. Burke,Akiva S. Cohen
Publisher : Frontiers Media SA
Release : 2017-04-27
ISBN : 2889450988
Language : En, Es, Fr & De

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Book Description :

Traumatic brain injury (TBI) is traditionally viewed as an anatomic and neuropathological condition. Caring for TBI patients is a matter of defining the extent of an anatomical lesion, managing this lesion, and minimizing secondary brain injury. On the research side, the effects of TBI often are studied in the context of neuronal and axonal degeneration and the subsequent deposition of abnormal proteins such as tau. These approaches form the basis of our current understanding of TBI, but they pay less attention to the function of the affected organ, the brain. Much can be learned about TBI by studying this disorder on a systems neuroscience level and correlating changes in neural circuitry with neurological and cognitive function. There are several aspects of TBI that are a natural fit for this perspective, including post-traumatic epilepsy, consciousness, and cognitive sequelae. How individual neurons contribute to network activity and how network function responds to injury are key concepts in examining these areas. In recent years, the available tools for studying the role of neuronal assemblies in TBI have become increasingly sophisticated, ranging from optogenetic and electrophysiological techniques to advanced imaging modalities such as functional magnetic resonance imaging and magnetoencephalography. Further progress in understanding the disruption and subsequent reshaping of networks is likely to have substantial benefits in the treatment of patients with TBI-associated deficits. In this Frontiers Topic, we intend to highlight the systems neuroscience approach to studying TBI. In addition to analyzing the clinical sequelae of TBI in this context, this series of articles explores the pathophysiological mechanisms underlying network dysfunction, including alterations in synaptic activity, changes in neural oscillation patterns, and disruptions in functional connectivity. We also include articles on treatment options for TBI patients that modulate network function. It is our hope that this Frontiers Topic will increase the clinical and scientific communities’ awareness of this viable framework for deepening our knowledge of TBI and improving patient outcomes.

Handbook of in Vivo Neural Plasticity Techniques

Handbook of in Vivo Neural Plasticity Techniques Book
Author : Anonim
Publisher : Academic Press
Release : 2018-09-01
ISBN : 0128120274
Language : En, Es, Fr & De

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Book Description :

Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques. Offers a comprehensive overview of state-of-the-art approaches to studying neuroplasticity in vivo Combines discussions of theoretical underpinnings with the methodological and technical aspects necessary to guarantee success Arranged in a uniform format that clearly and concisely lays out descriptions, methods and the pitfalls of various techniques

International Journal of Neuroscience

International Journal of Neuroscience Book
Author : Anonim
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Journal of Neuroscience book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Vulnerability to Depression

Vulnerability to Depression Book
Author : Rick E. Ingram,Ruth Ann Atchley,Zindel V. Segal
Publisher : Guilford Press
Release : 2011-07-07
ISBN : 160918257X
Language : En, Es, Fr & De

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Book Description :

Providing a cutting-edge examination of the mechanisms underlying depression, this volume integrates important areas of research that have largely remained separate. The authors explore both the cognitive and neurological processes that make some people more vulnerable than others to developing depression and experiencing recurrent episodes. They also probe how these processes interact—how negative life experiences, maladaptive belief systems, and patterns of thinking may actually affect neural circuitry, and vice versa. Explaining sophisticated theory and research in an accessible style, the book highlights the implications for improving clinical practices and patient outcomes.

Neuroreceptors in Health and Disease

Neuroreceptors in Health and Disease Book
Author : Jwahar Marwaha,William J. Anderson
Publisher : S Karger Ag
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Neuroreceptors in Health and Disease book written by Jwahar Marwaha,William J. Anderson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Climate Change and the Fate of the Amazon

Climate Change and the Fate of the Amazon Book
Author : Yadvinder Malhi,Richard A. Betts,J. Timmons Roberts
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Climate Change and the Fate of the Amazon book written by Yadvinder Malhi,Richard A. Betts,J. Timmons Roberts, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Dopaminergic System

Dopaminergic System Book
Author : Liana Bolis,Luca Pani,J. Licinio
Publisher : Lippincott Williams & Wilkins
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

In this volume an international, multidisciplinary group of experts reviews the latest findings on the biology of dopaminergic neurotransmission and the role of dopamine in the pathophysiology and treatment of disorders such as schizophrenia, depression, dysthymia, and motor diseases. The book integrates current knowledge on dopaminergic function from diverse areas of basic science and clinical research, including molecular biology, transgenic studies, biochemistry, genetics, brain imaging, neurology, and psychiatry.

Proceedings of the Indian National Science Academy

Proceedings of the Indian National Science Academy Book
Author : Indian National Science Academy
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Proceedings of the Indian National Science Academy book written by Indian National Science Academy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Psychiatry as Cognitive Neuroscience

Psychiatry as Cognitive Neuroscience Book
Author : Matthew Broome,Lisa Bortolotti
Publisher : Oxford University Press
Release : 2009-05-14
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

'Psychiatry as Cognitive Neuroscience' is a philosophical analysis of the study of psychpathology, considering how cognitive neuroscience has been applied in psychiatry. The text examines many neuroscientific methods, such as neuroimaging, and a variety of psychiatric disorders, including depression, and schizophrenia.

Psychiatry and Clinical Neuroscience

Psychiatry and Clinical Neuroscience Book
Author : Charles Zorumski,Eugene Rubin
Publisher : Oxford University Press
Release : 2011-06-16
ISBN : 0199768765
Language : En, Es, Fr & De

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Book Description :

Psychiatric disorders are brain disorders, reflecting dysfunction within and across neural networks. Advances in functional neuroimaging and cellular neuroscience offer hope of revolutionizing the approach to diagnosis and treatment of mental illnesses. This book presents an introduction to network neuroscience and demonstrates the relationship of advances in this field to the future of psychiatry.

The Thyroid Solution

The Thyroid Solution Book
Author : Ridha Arem
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Written by a leading authority on the subject, the first comprehensive guide to thyroid disorder explains the illness and its physical and emotional effects and offers a practical program for restoring one's thyroid to health and maintaining it.

The Neurobiology of Suicide

The Neurobiology of Suicide Book
Author : David M. Stoff,Joseph John Mann,American Suicide Foundation
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

As the ninth leading cause of death in the United States, suicide poses a major public health problem. Rather than scrutinizing the psychological and sociocultural factors that enhance risk, this work, in contrast, focuses on the biological determinants of suicide. It presents recent studies in suicide on basic research models, neurobiological factors, and treatment strategies. A critical theme addressed is the translation of findings from these studies across basic, neurobiological, and treatment domains.

Behavioural Neuroscience

Behavioural Neuroscience Book
Author : Arjun Sahgal
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Behavioural Neuroscience book written by Arjun Sahgal, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.