Skip to main content

Systems Biomedicine

In Order to Read Online or Download Systems Biomedicine Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Systems Biomedicine

Systems Biomedicine Book
Author : Edison T. Liu,Douglas A. Lauffenburger
Publisher : Academic Press
Release : 2009-09-17
ISBN : 9780080919836
Language : En, Es, Fr & De

GET BOOK

Book Description :

Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable Includes a thorough discussion of the applications of quantitative principles to biomedical problems

Comprehensive Systems Biomedicine

Comprehensive Systems Biomedicine Book
Author : Pietro Lio,Enrico Capobianco
Publisher : Frontiers E-books
Release : 2014-12-03
ISBN : 2889193748
Language : En, Es, Fr & De

GET BOOK

Book Description :

Systems Biomedicine is a field in perpetual development. By definition a translational discipline, it emphasizes the role of quantitative systems approaches in biomedicine and aims to offer solutions to many emerging problems characterized by levels and types of complexity and uncertainty unmet before. Many factors, including technological and societal ones, need to be considered. In particular, new technologies are providing researchers with the data deluge whose management and exploitation requires a reinvention of cross-disciplinary team efforts. The advent of “omics” and high-content imaging are examples of advances de facto establishing the necessity of systems approaches. Hypothesis-driven models and in silico validation tools in support to all the varieties of experimental applications call for a profound revision. The focus on phases like mining and assimilating the data has substantially increased so to allow for interpretable knowledge to be inferred. Notably, to be able to tackle the newly generated data dimensionality, heterogeneity and complexity, model-free and data-driven intensive applications are increasingly shaping the computational pipelines and architectures that quant specialists set aside of the high-throughput genomics, transcriptomics, proteomics platforms. As for the societal aspects, in many advanced societies health care needs now more than in the past to address the problem of managing ageing populations and their complex morbidity patterns. In parallel, there is a growing research interest on the impact that cross-disciplinary clinical, epidemiological and quantitative modelling studies can have in relation to outcomes potentially affecting the quality of life of many people. Complex systems, including those characterizing biomedicine, are assessed in both their functionality and stability, and also relatively to the capacity of generating information from diversity, variation, and complexity. Due to the combined interactions and effects, such systems embed prediction power available for instance in both target identification or marker discovery, or more generally for conducting inference about patients’ pathological states, i.e. normal versus disease, diagnostic or prognostic analysis, and preventive assessment (e.g., risk evaluation). The ultimate goal, personalized medicine, will be achieved based on the confluence of the system’s predictive power to patient-specific profiling.

New Challenges for Cancer Systems Biomedicine

New Challenges for Cancer Systems Biomedicine Book
Author : Alberto D'Onofrio,Paola Cerrai,Alberto Gandolfi
Publisher : Springer Science & Business Media
Release : 2013-01-25
ISBN : 8847025710
Language : En, Es, Fr & De

GET BOOK

Book Description :

The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include, not only bioinformatics and modern applied statistics, as is unanimously agreed, but also other interdisciplinary fields of science, notably, Mathematical Oncology, Systems Biology and Theoretical Biophysics.

Complex Systems in Biomedicine

Complex Systems in Biomedicine Book
Author : A. Quarteroni,L. Formaggia,A. Veneziani
Publisher : Springer Science & Business Media
Release : 2007-03-20
ISBN : 8847003962
Language : En, Es, Fr & De

GET BOOK

Book Description :

Mathematicalmodelingofhumanphysiopathologyisatremendouslyambitioustask. It encompasses the modeling of most diverse compartments such as the cardiovas- lar,respiratory,skeletalandnervoussystems,aswellasthemechanicalandbioch- ical interaction between blood ?ow and arterial walls, and electrocardiac processes and electric conduction in biological tissues. Mathematical models can be set up to simulate both vasculogenesis (the aggregation and organization of endothelial cells dispersed in a given environment) and angiogenesis (the formation of new vessels sprouting from an existing vessel) that are relevant to the formation of vascular networks, and in particular to the description of tumor growth. The integration of models aimed at simulating the cooperation and interrelation of different systems is an even more dif?cult task. It calls for the setting up of, for instance, interaction models for the integrated cardio-vascular system and the interplay between the central circulation and peripheral compartments, models for the mid-to-long range cardiovascular adjustments to pathological conditions (e.g., to account for surgical interventions, congenital malformations, or tumor growth), models for integration among circulation, tissue perfusion, biochemical and thermal regulation, models for parameter identi?cation and sensitivity analysis to parameter changes or data uncertainty – and many others.

Complex Systems Science in Biomedicine

Complex Systems Science in Biomedicine Book
Author : Thomas Deisboeck,J. Yasha Kresh
Publisher : Springer Science & Business Media
Release : 2007-06-13
ISBN : 9780387335322
Language : En, Es, Fr & De

GET BOOK

Book Description :

Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Systems Biology in Cancer Research and Drug Discovery

Systems Biology in Cancer Research and Drug Discovery Book
Author : Asfar S Azmi
Publisher : Springer Science & Business Media
Release : 2012-09-29
ISBN : 9400748191
Language : En, Es, Fr & De

GET BOOK

Book Description :

Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer.

A Systems Approach to Biomedicine

A Systems Approach to Biomedicine Book
Author : William B. Blesser
Publisher : Unknown
Release : 1969
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download A Systems Approach to Biomedicine book written by William B. Blesser, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomedicine and Alternative Healing Systems in America

Biomedicine and Alternative Healing Systems in America Book
Author : Hans A. Baer
Publisher : Univ of Wisconsin Press
Release : 2001
ISBN : 9780299166946
Language : En, Es, Fr & De

GET BOOK

Book Description :

Examining medical pluralism in the United States from the Revolutionary War period through the end of the twentieth century, Hans Baer brings together in one convenient reference a vast array of information on healing systems as diverse as Christian Science, osteopathy, acupuncture, evangelical faith healing, Santeria, southern Appalachian herbalism, and Navajo healing. In a country where the dominant paradigm of biomedicine (medical schools, research hospitals, clinics staffed by M.D.s and R.N.s) has been long established and supported by laws and regulations, the continuing appeal of other medical systems and subsystems bears careful consideration. Distinctions of class, Baer emphasizes, as well as differences in race, ethnicity, and gender, are fundamental to the diversity of beliefs, techniques, and social organizations represented in the phenomenon of medical pluralism. Baer traces the simultaneous emergence in the nineteenth century of formalized biomedicine and of homeopathy, botanic medicine, hydropathy, Christian Science, osteopathy, and chiropractic. He examines present-day osteopathic medicine as a system parallel to biomedicine; chiropractic, naturopathy, and acupunctur

Contaminated Sediments

Contaminated Sediments Book
Author : Ulrich Förstner
Publisher : Springer
Release : 1989-04-12
ISBN : 9783540510765
Language : En, Es, Fr & De

GET BOOK

Book Description :

Sediments are increasingly recognized as both a carrier and a possible source of contaminants in aquatic systems, and they may also affect groundwater quality and agricultural products when disposed on land. Four aspects are covered reflecting the development of knowledge in particle-associated pollutants during the past twenty-five years: - the identification, surveillance, monitoring and control of sources and distribution of pollutants, - the evaluation of solid/solution relations of contaminants in surface waters, - the study of in-situ processes and mechanisms of pollutant transfer in various compartments of the aquatic ecosystems, - the assessment of the environmental impact of particle-bound contaminants, i.e. the development of sediment quality criteria. A final chapter focusses on practical aspects concerning contaminated sediments.

Mathematical Modelling in Biomedicine

Mathematical Modelling in Biomedicine Book
Author : Y. Cherruault
Publisher : Springer Science & Business Media
Release : 1986-02-28
ISBN : 9789027721495
Language : En, Es, Fr & De

GET BOOK

Book Description :

Approach your problems from the right It isn't that they can't see the solution. It end and begin with the answers. Then is that they can't see the problem. one day, perhaps you will find the final question. G.K. Chesterton. The Scandal of Father Brown 'The point of a Pin'. 'The Hermit Clad in Crane Feathers' in R. van Gulik's The Chinese Maze Murders. Growing specialization and diversification have brought a host of monographs and textbooks on increasingly specialized topics. However, the "tree" of knowledge of mathematics and related fields does not grow only by putting forth new branches. It also happens, quite often in fact, that branches which were thought to be completely disparate are suddenly seen to be related. Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; algebraic geometry interacts with physics; the Minkowsky lemma, cod ing theory and the structure of water meet one another in packing and covering theory; quantum fields, crystal defects and mathematical pro gramming profit from homotopy theory; Lie algebras are relevant to filtering; and prediction and electrical engineering can use Stein spaces.

Computer Techniques in Biomedicine and Medicine

Computer Techniques in Biomedicine and Medicine Book
Author : Enoch Haga
Publisher : Unknown
Release : 1973
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Computer Techniques in Biomedicine and Medicine book written by Enoch Haga, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Basic Feedback Controls in Biomedicine

Basic Feedback Controls in Biomedicine Book
Author : Charles S. Lessard
Publisher : Morgan & Claypool Publishers
Release : 2009
ISBN : 1598299506
Language : En, Es, Fr & De

GET BOOK

Book Description :

This textbook is intended for undergraduate students (juniors or seniors) in Biomedical Engineering, with the main goal of helping these students learn about classical control theory and its application in physiological systems. In addition, students should be able to apply the Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW) Controls and Simulation Modules to mammalian physiology. The first four chapters review previous work on differential equations for electrical and mechanical systems. Chapters 5 through 8 present the general types and characteristics of feedback control systems and foot locus, frequency response, and analysis of stability and margins. Chapters 9 through 12 cover basic LabVIEW programming, the control module with its pallets, and the simulation module with its pallets. Chapters 13 through 17 present various physiological models with several LabVIEW control analyses. These chapters cover control of the heart (heart rate, stroke volume, and cardiac output), the vestibular system and its role in governing equilibrium and perceived orientation, vestibulo-ocular reflex in stabilizing an image on the surface of the retina during head movement, mechanical control models of human gait (walking movement), and the respiratory control model. The latter chapters (Chapters 13-17) combine details from my class lecture notes in regard to the application of LabVIEW control programming by the class to produce the control virtual instruments and graphical displays (root locus, Bode plots, and Nyquist plot). This textbook was developed in cooperation with National Instruments personnel. Table of Contents: Electrical System Equations / Mechanical Translation Systems / Mechanical Rotational Systems / Thermal Systems and Systems Representation / Characteristics and Types of Feedback Control Systems / Root Locus / Frequency Response Analysis / Stability and Margins / Introduction to LabVIEW / Control Design in LabVIEW / Simulation in LabVIEW / LabVIEW Control Design and Simulation Exercise / Cardiac Control / Vestibular Control System / Vestibulo-Ocular Control System / Gait and Stance Control System / Respiratory Control System

Mirror for Humanity

Mirror for Humanity Book
Author : Conrad Phillip Kottak
Publisher : Unknown
Release : 2003
ISBN : 9780072414875
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Mirror for Humanity book written by Conrad Phillip Kottak, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Health and Healing in Comparative Perspective

Health and Healing in Comparative Perspective Book
Author : Elizabeth Dixon Whitaker
Publisher : Pearson College Division
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

This reader provides both fascinating comparative ethnographic detail and a theoretical framework for organizing and interpreting information about health. While there are many health-related fields represented in this book, its core discipline is medical anthropology and its main focus is the comparative approach. Cross-cultural comparison gives anthropological analysis breadth while the evolutionary time scale gives it depth. These two features have always been fundamental to anthropology and continue to distinguish it among the social sciences. A third feature is the in-depth knowledge of culture produced by anthropological methods such as participant-observation, involving long-term presence in and research among a study population.The first part of the book explores healing systems in different cultures; the second and third provide a strong grounding in evolutionary and culture-oriented analysis, making clear the connections between biology and culture as they affect health; the final part emphasizes case studies that apply the theoretical principles presented earlier to particular health topics.For medical anthropology, medical sociology, public health, nursing, and medical training professionals.

NMR Imaging in Biomedicine

NMR Imaging in Biomedicine Book
Author : P Mansfield
Publisher : Elsevier
Release : 1982-04-28
ISBN : 0323154069
Language : En, Es, Fr & De

GET BOOK

Book Description :

NMR Imaging in Biomedicine: Advances in Magnetic Resonance discusses significant advances in NMR imaging and its application to the field of biomedicine. This book is organized into 10 chapters that cover the classification, methods, imaging regimes, and the potential use of NMR imaging in medicine. After discussing the basic theoretical ideas of NMR and its application to NMR imaging, this book presents mathematical analyses of the various NMR techniques, focusing primarily on the comparison in terms of imaging speed and data-acquisition rate. It also covers a number of practical ranges or imaging regimes in terms of sensitivity, sample size, and operating frequency. Significant topics on potential application of NMR imaging in medicine, apparatus requirements in the instrumentation of NMR imaging machines, and the principles of biomagnetic effects are discussed in other chapters. The considered biomagnetic effects are categorized into three main groups: the effects of static magnetic fields, the effects of relatively slow varying time-dependent fields, and radio-frequency magnetic fields. This book is of great value to radiologists, medical physicists, neuroradiologists, anatomists, physiologists, and postgraduate students of NMR imaging.

Science in Brazil

Science in Brazil Book
Author : Academia Brasileira de Ciências
Publisher : Unknown
Release : 2002
ISBN : 9788585761233
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Science in Brazil book written by Academia Brasileira de Ciências, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fundamentals of Complementary and Integrative Medicine

Fundamentals of Complementary and Integrative Medicine Book
Author : Marc S. Micozzi
Publisher : Saunders
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

This resource lays the groundwork for a solid understanding of complementary and integrative therapy. It provides insight into the historical context of alternative healing systems, as well as the most up-to-date scientific research and clinical applications for integrative medicine. Focusing on therapies best supported by clinical trials and evidence, it describes key concepts of the most prevalent complementary and alternative therapies in use today. This edition features many new chapters and a new appendix, with thorough updates and references throughout.

Biomedicine

Biomedicine Book
Author : Anonim
Publisher : Unknown
Release : 1973
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Biomedicine book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Hearings

Hearings Book
Author : Anonim
Publisher : Unknown
Release : 1963
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Hearings book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.