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Synapse Development And Maturation

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Synapse Development and Maturation

Synapse Development and Maturation Book
Author : Pasko Rakic,John Rubenstein,Bin Chen,Kenneth Y. Kwan
Publisher : Academic Press
Release : 2020-05-29
ISBN : 0128236736
Language : En, Es, Fr & De

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Book Description :

Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

From Neurons to Neighborhoods

From Neurons to Neighborhoods Book
Author : Division of Behavioral and Social Sciences and Education,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Publisher : National Academies Press
Release : 2000-11-13
ISBN : 0309069882
Language : En, Es, Fr & De

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Book Description :

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Discovering the Brain

Discovering the Brain Book
Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
Publisher : National Academies Press
Release : 1992-01-01
ISBN : 0309045290
Language : En, Es, Fr & De

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Book Description :

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brain--an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attention--and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniques--what various technologies can and cannot tell us--and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakers--and many scientists as well--with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Cellular Migration and Formation of Neuronal Connections

Cellular Migration and Formation of Neuronal Connections Book
Author : John Rubenstein,Pasko Rakic
Publisher : Unknown
Release : 2013
ISBN : 9780123972668
Language : En, Es, Fr & De

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Book Description :

This book offers the most thorough coverage and addresses all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms.

Encyclopedia of Neuroscience

Encyclopedia of Neuroscience Book
Author : Marc D. Binder,Nobutaka Hirokawa,Uwe Windhorst
Publisher : Springer
Release : 2008-10-13
ISBN : 9783540237358
Language : En, Es, Fr & De

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Book Description :

This 5000-page masterwork is literally the last word on the topic and will be an essential resource for many. Unique in its breadth and detail, this encyclopedia offers a comprehensive and highly readable guide to a complex and fast-expanding field. The five-volume reference work gathers more than 10,000 entries, including in-depth essays by internationally known experts, and short keynotes explaining essential terms and phrases. In addition, expert editors contribute detailed introductory chapters to each of 43 topic fields ranging from the fundamentals of neuroscience to fascinating developments in the new, inter-disciplinary fields of Computational Neuroscience and Neurophilosophy. Some 1,000 multi-color illustrations enhance and expand the writings.

Development of the Nervous System

Development of the Nervous System Book
Author : Dan H. Sanes,Thomas A. Reh,William A. Harris
Publisher : Elsevier
Release : 2005-11-02
ISBN : 9780080472492
Language : En, Es, Fr & De

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Book Description :

Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. Updates information including all the new developments made in the field since the first edition Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated

The Synapse

The Synapse Book
Author : Virginia M. Pickel,Menahem Segal
Publisher : Elsevier
Release : 2013-11-16
ISBN : 0124186823
Language : En, Es, Fr & De

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Book Description :

The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment

Molecular Mechanisms of Neural Development and Insights into Disease

Molecular Mechanisms of Neural Development and Insights into Disease Book
Author : Anonim
Publisher : Academic Press
Release : 2021-03-09
ISBN : 0128152826
Language : En, Es, Fr & De

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Book Description :

Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord, The role of astrocytes in synapse formation and maturation, Development of motor circuits, Molecular mechanisms that mediate dendrite morphogenesis, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series

The Fragile X Syndrome Where Do We Go

The Fragile X Syndrome     Where Do We Go  Book
Author : Regina Dahlhaus,Christian Gonzalez-Billault
Publisher : Frontiers Media SA
Release : 2021-12-22
ISBN : 288971845X
Language : En, Es, Fr & De

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Book Description :

Download The Fragile X Syndrome Where Do We Go book written by Regina Dahlhaus,Christian Gonzalez-Billault, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biology of the NMDA Receptor

Biology of the NMDA Receptor Book
Author : Antonius M. VanDongen
Publisher : CRC Press
Release : 2008-10-29
ISBN : 9781420044157
Language : En, Es, Fr & De

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Book Description :

The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.

The Dynamic Synapse

The Dynamic Synapse Book
Author : Josef T. Kittler,Stephen J. Moss
Publisher : CRC Press
Release : 2006-03-27
ISBN : 0203486285
Language : En, Es, Fr & De

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Book Description :

Exploring the diverse tools and technologies used to study synaptic processes, The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology delineates techniques, methods, and conceptual advances for studying neurotransmitter receptors and other synaptic proteins. It describes a broad range of molecular, biochemical, imaging, and electrophysiological approaches for studying the biology of synapses. Specific topics include the use of proteomics to study synaptic protein complexes, the development of phosphorylation state specific antibodies, post-genomic tools applied to the study of synapses and RNA interference in neurons. In addition, several chapters focus on methods for gene and protein delivery into neuronal tissue. The use of biochemical, electrophysiological and optical tagging techniques to study the movement and membrane trafficking of neurotransmitter receptors in the membrane of live nerve cells are also discussed. To complement these approaches, the application of approaches for achieving long-term alterations in the genetic complement of neurons in vivo using viral vectors or homologous recombination of ES cells are also described.

Neurobehavioral Plasticity

Neurobehavioral Plasticity Book
Author : Norman E. Spear,Linda P. Spear,Michael L. Woodruff
Publisher : Psychology Press
Release : 2013-06-17
ISBN : 1134780850
Language : En, Es, Fr & De

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Book Description :

This book describes a unique combination of research programs based on a striking variety of hypotheses and procedures directed toward understanding the sources and consequences of neurobehavioral plasticity. This remarkable attribute of the nervous system -- to be pliable and capable of being shaped or formed by natural or artificial sources toward adaptation or maladaptation -- is considered in terms of the neurochemical forces and neuroanatomical structure that has been found to be pivotal for this function. The impetus for this volume was a symposium held to honor Robert L. Isaacson for his scientific and pedagogical achievements as well as his contributions to behavioral neuroscience. Corresponding to his three major research interests, the book is divided into three sections as follows: * the first explores the relationship between the limbic system and behavior, with an emphasis on learning and memory; * the second considers -- through a wide range of approaches -- issues of plasticity in behavior and brain; and * the third deals with neural and chemical determinants of normal and abnormal behavior. This volume is not only a fitting tribute to Isaacson, but also an unusual collection of new evidence, procedures, and theories destined to have significant influence on behavioral neuroscience.

Make Life Visible

Make Life Visible Book
Author : Yoshiaki Toyama,Atsushi Miyawaki,Masaya Nakamura,Masahiro Jinzaki
Publisher : Springer Nature
Release : 2019-10-02
ISBN : 9811379084
Language : En, Es, Fr & De

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Book Description :

This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.

Development Maturation and Senescence of Neuroendocrine Systems

Development  Maturation  and Senescence of Neuroendocrine Systems Book
Author : Colin Scanes
Publisher : Elsevier
Release : 2012-12-02
ISBN : 0323150128
Language : En, Es, Fr & De

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Book Description :

Development, Maturation, and Senescence of Neuroendocrine Systems: A Comparative Approach discusses the various phases of the aging continuum of neuroendocrine systems. This book explores the fundamental and physiological component of animals, which is an essential contributor to senescence. Organized into three parts encompassing 21 chapters, this volume starts with a discussion of the concept of neurosecretory neuron that was introduced by Ernst Scharrer in 1928. This book discusses the challenges in the study of the development of the neuroendocrine system in insects, with a focus on Lepidoptera. Other chapters consider the neuroendocrine mechanisms that control the physiological processes in crustaceans. The reader is then introduced to the major neurohemal structures in crustaceans, including the sinus gland, the pericardial organs, and the post-commissural organs. The final chapter discusses the two brain systems that show impact of endogenous steroids that account for subsets of senescent changes. This book is a valuable resource for neurobiologists, molecular biologists, and immunologists.

Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases

Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases Book
Author : Tuan Leng Tay,Giuseppe Locatelli,Gabriela Constantin,V. Wee Yong
Publisher : Frontiers Media SA
Release : 2022-05-03
ISBN : 2889760707
Language : En, Es, Fr & De

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Book Description :

Download Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases book written by Tuan Leng Tay,Giuseppe Locatelli,Gabriela Constantin,V. Wee Yong, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Developmental Neurobiology

Developmental Neurobiology Book
Author : Greg Lemke
Publisher : Academic Press
Release : 2010-05-22
ISBN : 9780123751676
Language : En, Es, Fr & De

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Book Description :

Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject. The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook information The 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the Encyclopedia of Neuroscience by one of the great developmental neuroscientists, Greg Lemke The best researchers in the field provide their conclusions in the context of the latest experimental results

Cell Type Diversity in the Nervous System From Genes to Function

Cell Type Diversity in the Nervous System  From Genes to Function Book
Author : Miao He,Giordano Lippi,Jiangteng Lu
Publisher : Frontiers Media SA
Release : 2022-02-04
ISBN : 2889743365
Language : En, Es, Fr & De

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Book Description :

Download Cell Type Diversity in the Nervous System From Genes to Function book written by Miao He,Giordano Lippi,Jiangteng Lu, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Intercellular Communication in the Nervous System

Intercellular Communication in the Nervous System Book
Author : Robert Malenka
Publisher : Academic Press
Release : 2010-05-22
ISBN : 0123785723
Language : En, Es, Fr & De

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Book Description :

Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/receptors, synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signaling controls neuroendocrinology, neuroimmunology and neuropharmacology. Intercellular Communication in the Nervous System provides a valuable desk reference for all scientists who consider signaling. * Chapters offer impressive scope with topics addressing neurotransmitters/receptors, synaptic structure and organization, neuropeptides, gap junctions, neuropharmacology and more * Richly illustrated in full color with over 200 figures * Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Development and Plasticity in Sensory Thalamus and Cortex

Development and Plasticity in Sensory Thalamus and Cortex Book
Author : Reha Erzurumlu,William Guido,Zoltan Molnar
Publisher : Springer Science & Business Media
Release : 2006-10-28
ISBN : 0387386076
Language : En, Es, Fr & De

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Book Description :

This volume provides an update on the multitude of technical and experimental approaches in understanding the development and plasticity of the mammalian sensory thalamus and neocortex. The focus is on visual and somatosensory thalamus and neocortex in rodents and carnivores, and functional imaging studies in developing and aging human neocortex. It further provides a synthetic theoretical framework for future studies.

Synaptic Assembly and Neural Circuit Development

Synaptic Assembly and Neural Circuit Development Book
Author : Jaewon Ko,Chen Zhang
Publisher : Frontiers Media SA
Release : 2018-11-02
ISBN : 2889456307
Language : En, Es, Fr & De

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Book Description :

Download Synaptic Assembly and Neural Circuit Development book written by Jaewon Ko,Chen Zhang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.