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Supercritical Fluid Chromatography

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Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : Gérard Rossé
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2018-12-17
ISBN : 3110500779
Language : En, Es, Fr & De

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Book Description :

Supercritical Fluid Chromatography (SFC) provides a timely overview of SFC application areas which were unimaginable just a decade ago. This two-volume series opens with an overview of the history and expectant future of SFC and continues with recent applications in the pharmaceutical industry and other fascinating areas of science. SFC has found its place in the pharmaceutical industry with an increasing body of applications for chiral and achiral molecules in both the research and development phases of the drug discovery process. As illustrated in this two-volume series, the current interest in SFC extends well beyond the pharmaceutical industry. Chapters encompassing applications for polar and non-polar mixtures of importance are covering widely disparate areas in substance abuse, natural products including cannabinoids, bioactive lipids, flavor and fragrance. With its broad balance and coverage, this two-volume book constitutes a unique educational platform to students and scientists for many years to come. The major objective of this book editions is to inspire and stimulate readers to continue exploring the possibilities of exploiting supercritical fluids as a particular media for analysis, purifications and synthesis

Practical Supercritical Fluid Chromatography and Extraction

Practical Supercritical Fluid Chromatography and Extraction Book
Author : Thomas Caudell
Publisher : Routledge
Release : 2018-05-08
ISBN : 1351422502
Language : En, Es, Fr & De

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Book Description :

An exploration of fundamental as well as practical aspects of supercritical fluid chromatography and extraction. It addresses topics such as: packed columns in SFC; detection in SFC; supercritical fluid chromatography/mass spectroscopy; and evaporative light scattering detection in SFC.

Hyphenated Techniques in Supercritical Fluid Chromatography and Extraction

Hyphenated Techniques in Supercritical Fluid Chromatography and Extraction Book
Author : K. Jinno
Publisher : Elsevier
Release : 1992-07-21
ISBN : 9780080858616
Language : En, Es, Fr & De

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Book Description :

This is the first book to focus on the latest developments in hyphenated techniques using supercritical fluids. The advantages of SFC in hyphenation with various detection modes, such as FTIR, MS, MPD and ICP and others are clearly featured throughout the book. Special attention is paid to coupling of SFE with GC or SFC. In this edited volume, chapters are written by leading experts in the field. The book will be of interest to professionals in academia, as well as to those researchers working in an industrial environment, such as analytical instrumentation, pharmaceuticals, agriculture, food, petrochemicals and environmental.

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : Colin F. Poole
Publisher : Elsevier
Release : 2017-02-16
ISBN : 0128093676
Language : En, Es, Fr & De

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Book Description :

Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated. Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level. Edited and authored by world-leading chromatography experts Provides comprehensive coverage of SFC in a single source Extensive referencing facilitates identification of key research developments More than 200 figures and tables aid in the retention of key concepts

Supercritical Fluid Chromatography And Micro hplc

Supercritical Fluid Chromatography And Micro hplc Book
Author : M. Yoshioka
Publisher : VSP
Release : 1989
ISBN : 9789067641135
Language : En, Es, Fr & De

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Book Description :

Download Supercritical Fluid Chromatography And Micro hplc book written by M. Yoshioka, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Supercritical Fluid Chromatography with Patked Columns

Supercritical Fluid Chromatography with Patked Columns Book
Author : Klaus Anton,Claire Berger
Publisher : CRC Press
Release : 1997-09-19
ISBN : 9780824700133
Language : En, Es, Fr & De

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Book Description :

From the analytical to industrial preparative scale, this work provides a praxis-oriented overview of packed column supercritical fluid chromatography. It discusses and evaluates established applications and techniques, up-to-date and promising developments, and commercial instrumentation devices for use in industry. The book also reveals possibilities for problem solving and future innovations.

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : Smith
Publisher : RSC Chromatography Monographs
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Theory and principles of supercritical fluid cgromatography. The emergence and instrumentation of SFC. Selection of conditions for an SFC separation. Opens columns or pachked columns for supercritical fluid chromatography. HT-CGC and CSFC for the analysis of relatively high molecular weight compounds. Supercritical fluid chromatography mass spectrometry. SFC-MS in the pharmaceutical industry. Fractionation by coupled micro-supercritical fluid extraction and supercritical fluid chromatogrpahy.

Applications of Supercritical Fluids in Industrial Analysis

Applications of Supercritical Fluids in Industrial Analysis Book
Author : J.R. Dean
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 940112146X
Language : En, Es, Fr & De

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Book Description :

The continued search for rapid, efficient and cost-effective means of analytical measurement has introduced supercritical fluids into the field of analytical chemistry. Two areas are common: supercritical fluid chroma tography and supercritical fluid extraction. Both seek to exploit the unique properties of a gas at temperatures and pressures above the critical point. The most common supercritical fluid is carbon dioxide, employed because of its low critical temperature (31 °C), inertness, purity, non-toxicity and cheapness. Alternative supercritical fluids are also used and often in conjunction with modifiers. The combined gas-like mass transfer and liquid-like solvating characteristics have been used for improved chroma tographic separation and faster sample preparation. Supercritical fluid chromatography (SFC) is complementary to gas chro matography ( GC) and high performance liquid chromatography (HPLC), providing higher efficiency than HPLC, together with the ability to analyse thermally labile and high molecular weight analytes. Both packed and open tubular columns can be employed, providing the capability to analyse a wide range of sample types. In addition, flame ionization detection can be used, thus providing 'universal' detection.

Modern Supercritical Fluid Chromatography

Modern Supercritical Fluid Chromatography Book
Author : Larry M. Miller,J. David Pinkston,Larry T. Taylor
Publisher : John Wiley & Sons
Release : 2019-11-05
ISBN : 1119625998
Language : En, Es, Fr & De

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Book Description :

Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.

Modern Supercritical Fluid Chromatography

Modern Supercritical Fluid Chromatography Book
Author : Curt M. White
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Modern Supercritical Fluid Chromatography book written by Curt M. White, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : Gregory K. Webster
Publisher : CRC Press
Release : 2014-02-04
ISBN : 9814463019
Language : En, Es, Fr & De

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Book Description :

Analytical chemists in the pharmaceutical industry are always looking for more-efficient techniques to meet the analytical challenges of today’s pharmaceutical industry. One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by providing efficient and selective testing capabilities on the analytical and preparative scale. The supercritical fluid mobile phase, consisting mainly of CO2, facilitates cost reduction costs and helps the industry in meeting green chemistry standards. This book provides a comprehensive overview of the use of SFC in pharmaceutical analysis. Supercritical Fluid Chromatography reviews the use of SFC in drug-discovery applications and describes its application in drug development. When a drug is developed and brought to market, it is tested many times for impurities and degradants, enantiomeric purity, and analytical and preparative isolations—it is tested during discovery and development and for under-regulated and unregulated methodologies. The book describes the use of SFC for each of these applications and discusses more in-depth topics, such as the use of SFC in mass spectrometric and polarographic detection. The book also sheds light on the role of SFC in drug development from natural products and the advancement of SFC with new technologies and its use in pilot-scale operations as a chromatographic technique.

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : The Open The Open Courses Library
Publisher : Unknown
Release : 2019-12-02
ISBN : 9781670679260
Language : En, Es, Fr & De

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Book Description :

Supercritical Fluid Chromatography Physical Methods in Chemistry and Nano Science Supercritical fluid chromatography (SFC) begins its history in 1962 under the name "high pressure gas chromatography". It started off slow and was quickly overshadowed by the development of high performance liquid chromatography (HPLC) and the already developed gas chromatography. SFC was not a popular method of chromatography until the late 1980s, when more publications began exemplifying its uses and techniques. Chapter Outline: Supercritical fluids The instrument Advantages of supercritical fluid chromatography Applications The Open Courses Library introduces you to the best Open Source Courses.

Application of Supercritical Fluid Chromatography SFC for On line Analysis

Application of Supercritical Fluid Chromatography  SFC  for On line Analysis Book
Author : D. Upnmoor,G. Brunner
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Application of Supercritical Fluid Chromatography SFC for On line Analysis book written by D. Upnmoor,G. Brunner, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Analysis with Supercritical Fluids

Analysis with Supercritical Fluids Book
Author : Bernd Wenclawiak
Publisher : Springer Verlag
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Analysis with Supercritical Fluids book written by Bernd Wenclawiak, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Significance of CO2 Compressibility in Supercritical Fluid Chromatography

Significance of CO2 Compressibility in Supercritical Fluid Chromatography Book
Author : Charles Kerry Huston
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Significance of CO2 Compressibility in Supercritical Fluid Chromatography book written by Charles Kerry Huston, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : Larry T. Taylor
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Supercritical Fluid Chromatography book written by Larry T. Taylor, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.