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Strategies For Curative Fluorescence Guided Surgery Of Cancer

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Strategies for Curative Fluorescence Guided Surgery of Cancer

Strategies for Curative Fluorescence Guided Surgery of Cancer Book
Author : Robert Hoffman,Michael Bouvet
Publisher : Academic Press
Release : 2020-05-27
ISBN : 0128126779
Language : En, Es, Fr & De

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Book Description :

Strategies for Curative Fluorescence-Guided Surgery of Cancer is the first book to discuss how fluorescence-guided surgery can be successfully used during surgeries with several tumor types. FGS is one of the most exciting emerging modalities of surgery, especially cancer surgery, as it potentially allows the surgeon to visualize the actual margin of the tumor, thus greatly increasing the possibility of curative resection. The book discusses the applicability of FGS for several types of cancer, such as pancreatic cancer, liver metastasis, soft-tissue sarcoma, glioma, melanoma, and breast and lung cancer. This book is a valuable resource for cancer surgeons, cancer researchers and members of several other areas in the biomedical field who are interested in understanding this powerful technique. Presents an overview of fluorescence-guided surgery Explains general strategies for curative fluorescence-guided surgery and their applicability for each major tumor type Discusses the current and future achievements of FGS as a precise technique for cancer surgeries

How Do Metabolism Angiogenesis and Hypoxia Modulate Resistance

How Do Metabolism  Angiogenesis  and Hypoxia Modulate Resistance  Book
Author : Matilde Esther LLeonart,Josep Castellvi,Hiroshi Kondoh
Publisher : Frontiers Media SA
Release : 2021-05-25
ISBN : 2889668010
Language : En, Es, Fr & De

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Book Description :

Download How Do Metabolism Angiogenesis and Hypoxia Modulate Resistance book written by Matilde Esther LLeonart,Josep Castellvi,Hiroshi Kondoh, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Patient Derived Tumor Xenograft Models

Patient Derived Tumor Xenograft Models Book
Author : Rajesh Uthamanthil,Peggy Tinkey,Elisa de Stanchina
Publisher : Academic Press
Release : 2016-10-13
ISBN : 0128040610
Language : En, Es, Fr & De

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Book Description :

Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry

Theranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer Book
Author : Ganji Purnachandra Nagaraju,Sarfraz Ahmad
Publisher : Academic Press
Release : 2019-08-19
ISBN : 0128194588
Language : En, Es, Fr & De

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Book Description :

Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer“/li> Discusses treatment options available currently and prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment

Hepatobiliary Surgery

Hepatobiliary Surgery Book
Author : Ronald S. Chamberlain
Publisher : CRC Press
Release : 2003-01-01
ISBN : 1498712940
Language : En, Es, Fr & De

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Book Description :

This book is written as a reference and guidebook for practicing surgeons, gastroenterologists, and interventional radiologists with an interest in hepatobiliary diseases. It presents a strategy to enhance surgeons practice and the care of patients.

Fluorescent Imaging

Fluorescent Imaging Book
Author : N. Kokudo,T. Ishizawa
Publisher : Karger Medical and Scientific Publishers
Release : 2013-09-10
ISBN : 3318022934
Language : En, Es, Fr & De

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Book Description :

Indocyanine green (ICG) fluorescence has been used for imaging purposes for more than half a century; First employed by ophthalmologists for visualizing the retinal artery in the late 1960s, the application of ICG fluorescence imaging has since been continuously expanded. Recently, advances in imaging technologies have led to renewed attention regarding the use of ICG in the field of hepatobiliary surgery, as a new tool for visualizing the biliary tree and liver tumors.

Molecular Probes for Pancreatic Cancer Imaging

Molecular Probes for Pancreatic Cancer Imaging Book
Author : Anonim
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Pancreatic ductal adenocarcinoma (PDAC) has the poorest five-year survival rate of any cancer. Currently, there are no effective diagnostics or chemotherapeutics. Surgical resection is the only curative therapy. However, most patients experience recurrence due largely to challenges in assessing tumor margin status in the operating room. Molecular probes that selectively highlight pancreatic cancer tissue, having the potential to improve PDAC margin assessment intraoperatively, are urgently needed. In this work, a series of red and near-infrared fluorescent probes is reported. Two were found to distribute to normal pancreas following systemic administration. One selectively accumulates in genetically modified mouse models of PDAC, providing cancer-specific fluorescence. In contrast to the small molecule probes reported previously, it possesses inherent affinity for PDAC cells and tissue, and thus does not require conjugation to targeting agents. Moreover, the probe exhibits intracellular accumulation and enables visualization of four levels of structure including the whole organ, tissue, individual cells and subcellular organelles. It can thus promote new strategies for precision image-guided surgery, pancreatic cancer detection, the monitoring of therapeutic outcomes and basic research.

The Health Information Workforce

The Health Information Workforce Book
Author : Kerryn Butler-Henderson,Karen Day,Kathleen Gray
Publisher : Springer Nature
Release : 2021-11-10
ISBN : 3030818500
Language : En, Es, Fr & De

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Book Description :

This book provides a detailed guide to the highly specialised but little known health information workforce - people who are health informaticians, digital health experts, and managers of health data, health information and health knowledge. It explains the basis of their unique functions within healthcare – their educational pathways and standards, professional qualifications and industry certifications, scholarly foundations and principles of good practice. It explores their challenges, including the rise of the health consumer movement, the drive to improve equity and quality in healthcare, new technologies such as artificial intelligence, and the COVID-19 infodemic. Case studies describe how practitioners in real-world roles around the world are addressing the digital transformation of health. The Health Information Workforce: Current and Future Developments offers insights into a skilled group of people who are essential for healthcare services to function, for care providers to practice at the top of their scope, for researchers to generate significant insights, and for care consumers to be empowered participants in health systems. This book offers new perspectives for anyone working or intending to work in the health sector. It is a critical resource for health workforce planners, employers and educators seeking guidance on the specialised capabilities needed for high performance in an increasingly information-intensive sector.

Brain Tumors

Brain Tumors Book
Author : Amit Agrawal,Luis Rafael Moscote-Salazar
Publisher : BoD – Books on Demand
Release : 2018-08-22
ISBN : 1789235561
Language : En, Es, Fr & De

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Book Description :

We all know that the field of neuro-oncology is heterogeneous and under continuous development with the addition of new knowledge and information on a regular basis. The present book "Brain Tumor - An Update" is an attempt to share the personal experiences of experts who are involved in neuro-oncology-related research. Through this book, the authors share their experiences and provide details about the pathophysiology, neuroimaging approaches, and management options, and how to go about decision-making in patients with brain tumors. We hope that the valuable contributions from the authors shall facilitate understanding about brain tumors. I am grateful to all the authors who have contributed their tremendous expertise, and I would like to acknowledge the outstanding support of Ms. Danijela Sakic, Author Service Manager, IntechOpen Science, who collaborated tirelessly in crafting this book.

Radioguided Surgery

Radioguided Surgery Book
Author : Giuliano Mariani,Armando E. Giuliano,H. William Strauss
Publisher : Springer Science & Business Media
Release : 2010-05-10
ISBN : 0387383271
Language : En, Es, Fr & De

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Book Description :

This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.

Experimental Microsurgery

Experimental Microsurgery Book
Author : Sun Lee
Publisher : Igaku-Shoin Medical Publishers
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Experimental Microsurgery book written by Sun Lee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Staging Laparoscopy

Staging Laparoscopy Book
Author : P. Hohenberger,K. Conlon
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642562906
Language : En, Es, Fr & De

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Book Description :

Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

Oral Cancer Detection

Oral Cancer Detection Book
Author : Prashanth Panta
Publisher : Springer
Release : 2019-01-04
ISBN : 3319612557
Language : En, Es, Fr & De

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Book Description :

This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Comprehensive Biomedical Physics

Comprehensive Biomedical Physics Book
Author : Anonim
Publisher : Newnes
Release : 2014-07-25
ISBN : 0444536337
Language : En, Es, Fr & De

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Book Description :

Comprehensive Biomedical Physics is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Video Atlas of Intraoperative Applications of Near Infrared Fluorescence Imaging

Video Atlas of Intraoperative Applications of Near Infrared Fluorescence Imaging Book
Author : Essa M. Aleassa,Kevin M. El-Hayek
Publisher : Springer Nature
Release : 2020-03-24
ISBN : 3030380920
Language : En, Es, Fr & De

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Book Description :

​This book represents a head-to-toe guide for clinicians who are interested in applying real-time near infrared (NIR) imaging for their patients. Expert surgeons from around the globe share their experience with NIR imaging, most commonly performed using indocyanine green (ICG) fluorescence. The chapters are structured to include a brief background, indications for use, followed by a technical description of the procedure. Each chapter is also accompanied by video examples and detailed information about necessary equipment, drug dosing, and alternative techniques. A pitfalls section serves as a “lessons learned” segment to bookend each chapter. Authors represent a comprehensive list of surgical subspecialties ranging from neurosurgery to plastic surgery. While it is not meant to serve as an exhaustive summary of ICG use in surgery, the goal is to highlight the successful use of this technology in a number of settings. As the technology and applications continue to expand, Video Atlas of Intraoperative Applications of Near Infrared Fluorescence Imaging serves as a foundation upon which to build.

The Medicine of Light

The Medicine of Light Book
Author : Andrei V. Reshetnickov,M. Nathaniel Mead
Publisher : Unknown
Release : 2014
ISBN : 9789082333206
Language : En, Es, Fr & De

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Book Description :

Download The Medicine of Light book written by Andrei V. Reshetnickov,M. Nathaniel Mead, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Radioguided Surgery

Radioguided Surgery Book
Author : Ken Herrmann,Omgo Nieweg,Stephen P. Povoski
Publisher : Springer
Release : 2016-03-04
ISBN : 3319260510
Language : En, Es, Fr & De

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Book Description :

This book offers a comprehensive overview of the state of the art in the practice of radioguided surgery. The opening section is devoted to the basic physics principles for detection and imaging, radiation detection device technology, principles of surgical navigation, radionuclides and radiopharmaceuticals, and radiation safety. A series of chapters then address the clinical application of radioguided surgery for a variety of malignancies, including breast cancer, melanoma and other cutaneous malignancies, gynecologic malignancies, head and neck malignancies, thyroid cancer, urologic malignancies, colon cancer, gastroesophageal cancer, lung cancer, bone tumors, parathyroid adenomas, and neuroendocrine tumors. For each application, the recommended methodological approaches are discussed and the available cumulative clinical experiences of investigators from across the globe are reviewed. A conscious effort is made to highlight recent developments and innovative multidisciplinary approaches within each clinical area. Interesting issues and novel approaches are further explored through a collection of selected case reports at the end of the book. The contributing authors are all experts in their own fields, ensuring that the book will hold wide appeal for surgeons, surgical technologists, nuclear medicine physicians, nuclear medicine technologists, and various trainees.

Surgery of the Thyroid and Parathyroid Glands E Book

Surgery of the Thyroid and Parathyroid Glands E Book Book
Author : Gregory W. Randolph
Publisher : Elsevier Health Sciences
Release : 2020-03-14
ISBN : 0323661289
Language : En, Es, Fr & De

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Book Description :

Bringing together more than over 120 expert contributors from otolaryngology, general surgery, endocrinology, and pathology, Surgery of the Thyroid and Parathyroid Glands, 3rd Edition, presents an interdisciplinary approach to surgical management and treatment of benign and malignant disease. This renowned text/atlas is an ideal resource at all levels of surgical experience: for residents and junior surgeons, it clearly provides all relevant anatomy, surgical procedures, and workup; for experienced surgeons, it details the management of difficult cases, including revision surgery. Highly illustrated and accompanied by dozens of videos, this edition brings you up to date with the full continuum of care in thyroid and parathyroid surgery. Easy-to-follow, templated chapters cover preoperative evaluation, surgical anatomy, intraoperative techniques, and postoperative management, for a full range of disorders of the thyroid and parathyroid glands. More than 30 procedural videos walk you step by step through minimally invasive thyroid surgery, surgical anatomy and monitoring of the recurrent laryngeal nerve, surgery for locally advanced thyroid cancer and nodal disease, and more; plus 23 chapter guide videos from the authors with Surgical Text Video Editor-in-Chief Gregory W. Randolph, Jr . Coverage of cutting-edge topics includes recurrent laryngeal nerve monitoring, minimally invasive surgery and the role of PET in staging and surgical planning. Expert guidance on thyroid cancer, including multiple chapters on PTC, MTC and HCC, ATC and NIFTP. New chapters cover medical oncology and TKI therapy. Extensive coverage of key topics such as FNA mutational analysis, transoral and minimally invasive surgery, recurrent laryngeal nerve monitoring, management of RLN paralysis, all aspects of parathyroid disease, ethics, malpractice, and more.

Breast Disease

Breast Disease Book
Author : Adnan Aydiner,Abdullah İgci,Atilla Soran
Publisher : Springer
Release : 2016-05-09
ISBN : 331926012X
Language : En, Es, Fr & De

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Book Description :

This second volume of the handbook on breast disease provides a comprehensive overview of its clinical management and current therapies. It brings readers up to speed with the latest guidelines and therapeutic regimens in breast cancer and provides and in-depth account of current and new therapeutic approaches. Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget’s disease and phyllodes tumors, and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must- have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

ICG Fluorescence Imaging and Navigation Surgery

ICG Fluorescence Imaging and Navigation Surgery Book
Author : Mitsuo Kusano,Norihiro Kokudo,Masakazu Toi,Masaki Kaibori
Publisher : Springer
Release : 2016-03-11
ISBN : 4431555285
Language : En, Es, Fr & De

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Book Description :

This book presents a comprehensive overview and outlook for the future of indocyanine green (ICG) fluorescence navigation surgery, which is attracting clinical interest as a safe and less invasive procedure not only in detecting cerebral vessels, coronary arteries, and biliary trees, but also in identifying sentinel lymph nodes in cancer. The book starts with the characteristics of ICG and photodynamic cameras/endoscopes, followed by detailed descriptions of the applications of ICG fluorescence imaging in various areas such as ocular surgery, neurosurgery, cardiovascular surgery, and plastic surgery. It also covers identifying sentinel lymph nodes in breast cancer as well as cancers of the gastrointestinal tract, and provides valuable information for hepato-biliary-pancreatic surgeons, such as identifying tattooing of liver segments and bile leakage. Written entirely by experts in their respective areas, ICG Fluorescence Imaging and Navigation Surgery offers an essential resource for surgeons operating on cancers and vascular disorders in the brain and cardiovascular systems and in plastic surgery.