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Stem Cells In Organs

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Stem Cell Transplantation

Stem Cell Transplantation Book
Author : Carlos López-Larrea,Antonio López Vázquez,Beatriz Suárez Álvarez
Publisher : Springer Science & Business Media
Release : 2012-03-28
ISBN : 1461420989
Language : En, Es, Fr & De

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Book Description :

Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

Principles of Tissue Engineering

Principles of Tissue Engineering Book
Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
Publisher : Academic Press
Release : 2011-10-13
ISBN : 9780080548845
Language : En, Es, Fr & De

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Book Description :

First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike. New to this edition: *Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves *Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems

Essentials of Stem Cell Biology

Essentials of Stem Cell Biology Book
Author : Robert Lanza,Anthony Atala
Publisher : Academic Press
Release : 2013-08-31
ISBN : 0124104274
Language : En, Es, Fr & De

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Book Description :

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners, and students embracing the latest advances in stem cells. Representing the combined effort of 7 editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to the application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with a glossary, highlighted terms, and bibliographic entries replacing references

Stem Cell Repair and Regeneration

Stem Cell Repair and Regeneration Book
Author : Nataša Levičar,Nagy A Habib,Myrtle Y Gordon,Ioannis Dimarakis
Publisher : World Scientific
Release : 2008-04-29
ISBN : 190897902X
Language : En, Es, Fr & De

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Book Description :

Stem cells have generated considerable interest recently in the scientific, clinical, and public arenas. The third book in the Stem Cell Repair and Regeneration series offers contributions from numerous areas bridging medicine and the life sciences. Significant research activities in the tissue engineering or regenerative medicine (the term recently used) field started in the 1970s, and there is currently great excitement over the possibility of replacing damaged body parts through regenerative medicine. Potential strategies to replace, repair and restore the function of damaged tissues or organs include stem cell transplantation, transplantation of tissues engineered in the laboratory, and the induction of regeneration by the body's own cells. It is believed that novel cellular therapeutics outperform any medical device, recombinant protein or chemical compound. This volume explores novel stem cell therapeutic strategies for myriad diseases, including renal failure, retinal disease and myocardial infarction. Contents:The Biology of Human Mesenchymal Stem Cells (C Westwood & M O Clements)Mesenchymal Stem Cells: From Culture to Clinic (C A Gregory)Stem Cell Bioprocessing for Clinical Applications of Regenerative Medicine (A Mantalaris et al.)Defining and Overcoming the Immunological Barriers to Stem Cell Therapies (N J Robertson et al.)Activation of the Immune System: A Corollary of Transplantation with ES Cell-Derived Tissues (A S Boyd et al.)Suppression of HLA Expression by Lentivirus-Mediated Gene Transfer of siRNA Cassettes (N Kasahara)Cord Blood Cells for Myocardial Regeneration (C Stamm & M Nan)Clinical Trials in Cardiac Stem Cell Therapy: An Update (R Kam & I Dimarakis)Stem Cell Therapy in Neurodegenerative Disease (C T Flores & M Y Gordon)Adult Human Stem Cell Therapy for Ischemic Stroke (D Williamson et al.)Cell Therapy in Renal Disease (H D Humes)Regenerative Medicine of the Eye: A Short Review (D T Harris et al.)A Clearer View of Stem Cells in Retinal Disease (M D Hodges et al.)Limbal Epithelial Stem Cells: Biology and Therapeutic Potential (M Notara et al.)The Use of Mesenchymal Stem Cells for Bone and Cartilage Repair (R Behan et al.) Readership: Life science scientists; biomedical researchers; academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals. Keywords:Stem Cell;Cardiac;Renal;RetinalKey Features:Comprehensive and up-to-date overview for clinicians and scientistsContains chapters by the field's leading scientists from some of the world's top research institutions and universitiesChapters cover basic stem cell science and topics related to many areas of translational “from bench to bedside” stem cell researchInformation presented in a form accessible to all interested students, clinicians and scientists

Ethical Issues in Human Stem Cell Research Commissioned papers

Ethical Issues in Human Stem Cell Research  Commissioned papers Book
Author : United States. National Bioethics Advisory Commission
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Ethical Issues in Human Stem Cell Research Commissioned papers book written by United States. National Bioethics Advisory Commission, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Laser Manipulation of Cells and Tissues

Laser Manipulation of Cells and Tissues Book
Author : Michael W. Berns,Karl Otto Greulich
Publisher : Academic Press
Release : 2007-07-04
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The use of laser-based manipulation tools has literally exploded on the cell biology and molecular pathology scene, resulting in as many different laser micromanipulation systems as there are people using them. Laser Manipulation of Cells and Tissues ties all these systems and studies together, describing all of the different kinds of research and practical/analytical applications of laser manipulation. It also provides the reader with the basic information needed to actually build one's own laser micro-manipulation system. The combination of imaging and molecular probe technology with laser micromanipulation greatly extends the use of this technology in molecular, cellular, developmental and patho-biology/medicine. This book should be valuable to scientists, clinicians, and students in the fields of cell and developmental biology, cell physiology, cancer biology, pathology, and stem cell biology. Devotes four chapters to laser catapulting and capture of DNA and other cellular material for biochemical analysis - a major use of this technology that has been adapted for molecular pathology both in clinical medicine and research Discusses the theory of laser tweezers (optical tweezers) and its application to novel problems in biology Covers topics on optoporation (getting things into cells), uncaging of molecules, and the ability to collect and analyze nanomolar amounts of cell material by an array of biochemical/physical tools of particular interest to cell biologists and drug discovery researchers

Adult Stem Cells

Adult Stem Cells Book
Author : Kursad Turksen
Publisher : Springer Science & Business
Release : 2014-04-16
ISBN : 1461495695
Language : En, Es, Fr & De

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Book Description :

Adult Stem Cells, second edition, takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult stem cells, and more specifically tissue-specific adult stem cells, has advanced tremendously. And an increased interest in regenerative medicine and potential stem cell applications has driven a quest for better understanding of stem cell biology. In turn, this has spawned much activity on generation and utilization of more and better reagents to identify and isolate stem cells and stem cell-like subpopulations, and on assays elucidating their developmental or differentiation potential and functional integration with host tissues and organs. In this fully updated new edition, chapters cover topics ranging from signaling pathways maintaining stemness in hematopoietic cells to regeneration after injury and endocrine mechanisms underlying the stem cell theory of aging. Other chapters cover stem cells by organ or system including pituitary, cardiac, epithelial, teeth, lung, ovary, prostate, liver, and many more. Importantly, the authors of the chapters have not only summarized their successes, but have also summarized some of the difficulties that each particular field is still facing with respect to maximizing the utility of stem cells in clinical settings. Collectively, they impart both the excitement and challenges facing stem cell utilization for repair and regeneration making this book essential reading for those involved in stem cell research as well as those involved in clinical assays.

Handbook of Stem Cells

Handbook of Stem Cells Book
Author : Anthony Atala,Robert Lanza
Publisher : Academic Press
Release : 2012-12-31
ISBN : 0123859433
Language : En, Es, Fr & De

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Book Description :

New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world’s experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system. Provides comprehensive coverage on this highly topical subject Contains contributions by the foremost authorities and premiere names in the field of stem cell research Companion website - http://booksite.elsevier.com/9780123859426/ - contains over 250 color figures in presentation format

Stem Cell and Tissue Engineering

Stem Cell and Tissue Engineering Book
Author : Song Li,Nicolas L'Heureux,Jennifer H. Elisseeff
Publisher : World Scientific
Release : 2011
ISBN : 9814317055
Language : En, Es, Fr & De

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Book Description :

Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.

Stem Cells

Stem Cells Book
Author : Norman M. Ford,Michael Herbert
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Reviews the scientific, medical, legal, therapeutic and ethical aspects of stem cell research and technology needed to form considered views about this rapidly developing field from a Christian perspective.

Effects of the Local Organ and Systemic Environments on Stem Cell Aging

Effects of the Local Organ and Systemic Environments on Stem Cell Aging Book
Author : Morgan Erik Carlson
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This work uncovers mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans, and affect both embryonic and adult stem cells. Specifically, the effects of aged muscle and systemic niches on key molecular identifiers of regenerative potential of human embryonic stem cells (hESCs) and postnatal muscle stem cells (satellite cells) were examined. Results reveal that aged differentiated niches dominantly inhibit the expression of Oct4 in hESC and Myf-5 in activated satellite cells, and reduce proliferation and myogenic differentiation of both embryonic and tissue specific adult stem cells (ASCs). Therefore, the ability of hESCs, and the more differentiated myogenic ASCs to contribute to tissue repair in the old will be restricted, due to the conserved inhibitory influence of aged differentiated niches. Additionally, this work establishes that hESC-derived factors enhance the regenerative potential of both young and importantly, aged muscle stem cells in vitro and in vivo; thus, suggesting that the regenerative outcome of stem cell-based replacement therapies will be determined by a balance between negative influences of aged tissues on transplanted cells and positive effects of embryonic cells on the endogenous regenerative capacity.

Tissue and Organ Regeneration

Tissue and Organ Regeneration Book
Author : Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster
Publisher : CRC Press
Release : 2014-05-15
ISBN : 9814411671
Language : En, Es, Fr & De

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Book Description :

Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell–based techniques is that current therapies lack controlled environments that are crucial for regulating stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro- and nanotechnology hold great potential to fabricate biomimetic spatiotemporally controlled scaffolds as well as control stem cell behavior and fate by micro- and nanoscale cues. This book presents the latest micro- and nanotechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano- and microfabrication techniques and biomaterials for the regeneration of various tissues and organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, cardiac, and vascular tissues.

Ethical Issues in Human Stem Cell Research

Ethical Issues in Human Stem Cell Research Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Ethical Issues in Human Stem Cell Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Principles of Regenerative Medicine

Principles of Regenerative Medicine Book
Author : Anthony Atala,Robert Lanza,Robert Nerem,James A. Thomson
Publisher : Academic Press
Release : 2011-04-28
ISBN : 9780080555959
Language : En, Es, Fr & De

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Book Description :

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. * Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology * The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine * New discoveries from leading researchers on restoration of diseased tissues and organs

Stem Cells Heterogeneity in Different Organs

Stem Cells Heterogeneity in Different Organs Book
Author : Alexander Birbrair
Publisher : Springer Nature
Release : 2019-09-05
ISBN : 3030241084
Language : En, Es, Fr & De

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Book Description :

This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue. As the functions of these stem cells vary, this is very important for the application of stem cells in cell therapy. This book describes the many recent developments that have revealed completely different roles of distinct stem cells within the same organ. Stem Cells Heterogeneity in Different Organs provides a timely update on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. Taken with its companion volumes, Stem Cells Heterogeneity: Novel Concepts and Stem Cells Heterogeneity in Cancer, this book is essential reading for advanced cell biology students as well as researchers and clinicians working with stem cells.

Stem Cell Biology and Tissue Engineering in Dental Sciences

Stem Cell Biology and Tissue Engineering in Dental Sciences Book
Author : Ajaykumar Vishwakarma,Paul Sharpe,Songtao Shi,Murugan Ramalingam
Publisher : Academic Press
Release : 2014-11-05
ISBN : 0123977789
Language : En, Es, Fr & De

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Book Description :

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color

Stem Cell Applications in Diseases

Stem Cell Applications in Diseases Book
Author : Mikkel L. Sorensen
Publisher : Nova Publishers
Release : 2008
ISBN : 9781604562415
Language : En, Es, Fr & De

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Book Description :

Stem cells are the foundation cells for every organ, tissue and cell in the body. They are like a blank microchip that can ultimately be programmed to perform any number of specialised tasks. Stem cells are undifferentiated, "blank" cells that do not yet have a specific function. Under proper conditions, stem cells begin to develop into specialised tissues and organs. Additionally, stem cells are self-sustaining and can replicate themselves for long periods of time. These unique characteristics make stem cells very promising for supplying cells to treat debilitating diseases like Alzheimer's disease, cancer, Parkinson's disease, type-1 diabetes, spinal cord injury, stroke, burns, heart disease, osteoarthritis and rheumatoid arthritis. This new book presents the latest research in the field from around the world.

Stem Cells Handbook

Stem Cells Handbook Book
Author : Humana Press
Publisher : Springer Science & Business Media
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

An encyclopedic reference on stem cells, this text covers stem cell biology in regard to basic biological functions including morphogenesis and regeneration, isolation and characterization and stem cells in tissues.

Stem Cell Research

Stem Cell Research Book
Author : Nancy E. Snow
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This timely volume brings together essays by an internationally distinguished and diverse group of scholars. Contributors thoughtfully explore the ethical, public policy, and scientific implications of embryonic and adult stem cell research. Part one of the book offers a variety of scientific and public policy perspectives, including essays on stem cell plasticity and using umbilical cord blood as an alternative source of pluripotent stem cells. Part two vigorously examines the ethics of stem cell research and considers issues of social justice, morality, and public policy. Scientific alternatives, a natural law perspective regarding federal funding, and a discussion of the possible moral complicity of Catholic researchers are among the distinctive contributions made to the stem cell research debate by this collection. The objective and balanced discussions contained in this volume serve as an accessible introduction to the bioethical questions, issues, and problems surrounding stem cell research.

Stem Cells Heterogeneity in Cancer

Stem Cells Heterogeneity in Cancer Book
Author : Alexander Birbrair
Publisher : Springer
Release : 2020-10-02
ISBN : 9783030143688
Language : En, Es, Fr & De

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Book Description :

This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ. Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity – Novel Concepts, and Stem Cells Heterogeneity in Different Organs, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.