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Stem Cell Therapy

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Stem Cells and Cell Therapy

Stem Cells and Cell Therapy Book
Author : Mohamed Al-Rubeai,Mariam Naciri
Publisher : Springer Science & Business Media
Release : 2013-10-01
ISBN : 9400771967
Language : En, Es, Fr & De

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Book Description :

With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Stem Cell Therapy

Stem Cell Therapy Book
Author : Erik V. Greer
Publisher : Nova Publishers
Release : 2006
ISBN : 9781594548482
Language : En, Es, Fr & De

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Book Description :

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book brings together leading research from throughout the world in this frontier field.

Stem Cell Therapy for Diabetes

Stem Cell Therapy for Diabetes Book
Author : Shimon Efrat
Publisher : Springer Science & Business Media
Release : 2009-12-01
ISBN : 9781607613664
Language : En, Es, Fr & De

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Book Description :

Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

Stem Cell Repair and Regeneration

Stem Cell Repair and Regeneration Book
Author : Nataša Levičar,Nagy A Habib,Myrtle Y Gordon,Ioannis Dimarakis
Publisher : World Scientific
Release : 2008-04-29
ISBN : 190897902X
Language : En, Es, Fr & De

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Book Description :

Stem cells have generated considerable interest recently in the scientific, clinical, and public arenas. The third book in the Stem Cell Repair and Regeneration series offers contributions from numerous areas bridging medicine and the life sciences. Significant research activities in the tissue engineering or regenerative medicine (the term recently used) field started in the 1970s, and there is currently great excitement over the possibility of replacing damaged body parts through regenerative medicine. Potential strategies to replace, repair and restore the function of damaged tissues or organs include stem cell transplantation, transplantation of tissues engineered in the laboratory, and the induction of regeneration by the body's own cells. It is believed that novel cellular therapeutics outperform any medical device, recombinant protein or chemical compound. This volume explores novel stem cell therapeutic strategies for myriad diseases, including renal failure, retinal disease and myocardial infarction. Contents:The Biology of Human Mesenchymal Stem Cells (C Westwood & M O Clements)Mesenchymal Stem Cells: From Culture to Clinic (C A Gregory)Stem Cell Bioprocessing for Clinical Applications of Regenerative Medicine (A Mantalaris et al.)Defining and Overcoming the Immunological Barriers to Stem Cell Therapies (N J Robertson et al.)Activation of the Immune System: A Corollary of Transplantation with ES Cell-Derived Tissues (A S Boyd et al.)Suppression of HLA Expression by Lentivirus-Mediated Gene Transfer of siRNA Cassettes (N Kasahara)Cord Blood Cells for Myocardial Regeneration (C Stamm & M Nan)Clinical Trials in Cardiac Stem Cell Therapy: An Update (R Kam & I Dimarakis)Stem Cell Therapy in Neurodegenerative Disease (C T Flores & M Y Gordon)Adult Human Stem Cell Therapy for Ischemic Stroke (D Williamson et al.)Cell Therapy in Renal Disease (H D Humes)Regenerative Medicine of the Eye: A Short Review (D T Harris et al.)A Clearer View of Stem Cells in Retinal Disease (M D Hodges et al.)Limbal Epithelial Stem Cells: Biology and Therapeutic Potential (M Notara et al.)The Use of Mesenchymal Stem Cells for Bone and Cartilage Repair (R Behan et al.) Readership: Life science scientists; biomedical researchers; academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals. Keywords:Stem Cell;Cardiac;Renal;RetinalKey Features:Comprehensive and up-to-date overview for clinicians and scientistsContains chapters by the field's leading scientists from some of the world's top research institutions and universitiesChapters cover basic stem cell science and topics related to many areas of translational “from bench to bedside” stem cell researchInformation presented in a form accessible to all interested students, clinicians and scientists

Biomaterials for Stem Cell Therapy

Biomaterials for Stem Cell Therapy Book
Author : Loredana De Bartolo,Augustinus Bader
Publisher : CRC Press
Release : 2013-01-28
ISBN : 1466576405
Language : En, Es, Fr & De

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Book Description :

Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair and cardiovascular therapy. Developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view. The book will be a valuable tool for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells. It will also be a source of reference for students in biotechnology, biomedical engineering, biology, biochemistry, materials sciences, pharmaceuticals, and veterinary and human medicine.

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy Book
Author : Lucas G. Chase,Mohan C Vemuri
Publisher : Springer Science & Business Media
Release : 2012-12-12
ISBN : 1627032002
Language : En, Es, Fr & De

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Book Description :

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Handbook of Cardiac Stem Cell Therapy

Handbook of Cardiac Stem Cell Therapy Book
Author : Ioannis Dimarakis
Publisher : World Scientific
Release : 2009
ISBN : 1848162561
Language : En, Es, Fr & De

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Book Description :

This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals. So, beyond being excellent as an overall update for scientists in the field of cardiac stem cell therapy, this book will likely prove an indispensable tool for every budding scientist considering a research project within this field.

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair Book
Author : Nabil Dib,Doris A. Taylor
Publisher : Springer Science & Business Media
Release : 2006
ISBN : 9780387257884
Language : En, Es, Fr & De

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Book Description :

With insights from world authorities, including scientists and regulatory authorities, this book presents a review of stem cell therapy for the treatment of cardiovascular disease. The contributions in basic science, pre-clinical and clinical experience, assure a rapid course of translational research and clinical trials.

Stem Cell Therapy for Autoimmune Disease

Stem Cell Therapy for Autoimmune Disease Book
Author : Richard K. Burt
Publisher : CRC Press
Release : 2019-11-11
ISBN : 1000724670
Language : En, Es, Fr & De

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Book Description :

Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.

Stem Cells

Stem Cells Book
Author : Mariusz Z. Ratajczak
Publisher : Springer Nature
Release : 2020-01-02
ISBN : 3030312062
Language : En, Es, Fr & De

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Book Description :

Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.

Regenerative Medicine and Cell Therapy

Regenerative Medicine and Cell Therapy Book
Author : Hossein Baharvand,Nasser Aghdami
Publisher : Springer Science & Business Media
Release : 2012-08-09
ISBN : 1627030980
Language : En, Es, Fr & De

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Book Description :

Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Umbilical Cord Stem Cell Therapy

Umbilical Cord Stem Cell Therapy Book
Author : David A. Steenblock,Anthony G. Payne
Publisher : Basic Health Publications, Inc.
Release : 2006
ISBN : 9781591201250
Language : En, Es, Fr & De

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Book Description :

Examines the potential for stem cells gleaned from umbilical cords to generate a wealth of new therapy and healing medicines for neurological conditions and blood problems.

Advances in Stem Cell Research

Advances in Stem Cell Research Book
Author : Hossein Baharvand,Nasser Aghdami
Publisher : Springer Science & Business Media
Release : 2012-05-26
ISBN : 1617799408
Language : En, Es, Fr & De

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Book Description :

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

The Stem Cell Cure

The Stem Cell Cure Book
Author : Gaurav K. Goswami, MD,Kerry Johnson MBA PhD
Publisher : Humanix Books
Release : 2020-03-31
ISBN : 1630061190
Language : En, Es, Fr & De

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Book Description :

The 150+ year lifespan of our ancient ancestors can be achieved once again by harnessing the power of our own cells with The Stem Cell Cure! Renowned regenerative and restorative sports medicine doctor Gaurav Goswami, M.D. provides advanced minimally invasive, non-surgical treatments to help his patients get back to peak performance levels – no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of Stem Cell Therapy – the biggest revolution in medicine since the discovery of penicillin, and a wave of the future. Co-authored by bestselling author and popular keynote speaker Kerry Johnson MBA PhD, The Stem Cell Cure provides specific ways for readers to boost their health and vitality for a lifetime by recovering, regenerating, and repairing injuries and disease.

Cardiovascular Regeneration and Stem Cell Therapy

Cardiovascular Regeneration and Stem Cell Therapy Book
Author : Annarosa Leri,Piero Anversa,William H. Frishman
Publisher : John Wiley & Sons
Release : 2008-04-15
ISBN : 0470994304
Language : En, Es, Fr & De

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Book Description :

This book is the definitive reference on two of the most exciting areas of cardiovascular research – myocardial regeneration and stem cell therapy – for the treatment of disease. Edited by pioneers in the area, with contributions from every major investigator worldwide, it covers: The biology of stem cells The actions of stem cells from the bone marrow, the heart, and embryos on the normal restorative and repair functions of the heart and blood vessels How stem cells could contribute to myocardial recovery in the face of injury and aging How adjuvant therapy with growth factors might enhance stem cell activity in regeneration and repair Clinical applications and clinical experiences This fully referenced publication presents the current state of knowledge in both basic science and clinical practice, and is an essential reference for scientists, students, and clinicians.

Stem Cells

Stem Cells Book
Author : Eapen Cherian,Cherian Eapen,G. Nandhini,Nandhini G,Kurian Anil
Publisher : JP Medical Ltd
Release : 2011-07
ISBN : 9789350250600
Language : En, Es, Fr & De

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Book Description :

Beginning with a basic introduction to the field, this book provides a comprehensive review of the properties and potential uses of stem cells, including stem cells in tissue engineering, cancer, gene therapy and in dental tissues. Stem Cells compares two key types of mammalian stem cell - embryonic and adult. Different stem cell systems are discussed, as well as potential obstacles in the use of human stem cells.

The Future of Brain Repair

The Future of Brain Repair Book
Author : Jack Price
Publisher : MIT Press
Release : 2020-03-24
ISBN : 0262357909
Language : En, Es, Fr & De

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Book Description :

A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer's disease, and Parkinson's disease. Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In this book, neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer's disease, Parkinson's disease, and spinal cord injuries. Certainly brain disorders are in need of effective treatments. These disorders don't just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells—and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinson's and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body. New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair?

Stem Cell Therapy A Rising Tide How Stem Cells Are Disrupting Medicine and Transforming Lives

Stem Cell Therapy  A Rising Tide  How Stem Cells Are Disrupting Medicine and Transforming Lives Book
Author : Neil H. Riordan
Publisher : Neil H Riordan
Release : 2017-06-20
ISBN : 9780999045305
Language : En, Es, Fr & De

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Book Description :

Stem cells are the repair cells of your body. When there aren't enough of them, or they aren't working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine's Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they're the wave of the future.

Stem Cell Transplantation

Stem Cell Transplantation Book
Author : Carlos López-Larrea,Antonio López Vázquez,Beatriz Suárez Álvarez
Publisher : Springer Science & Business Media
Release : 2012-03-28
ISBN : 1461420989
Language : En, Es, Fr & De

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Book Description :

Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

Stem Cells and the Stem Cell Therapy

Stem Cells and the Stem Cell Therapy  Book
Author : Harmony Owen
Publisher : Unknown
Release : 2019-11-06
ISBN : 9781706102014
Language : En, Es, Fr & De

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Book Description :

STEM CELLS AND THE STEM CELL THERAPY.It's contemporary benefits.The term "stem cell" is a general word used for describing the cells that possess the will power for an unending self-reproduction and still retaining its own original properties. This self-renewal ability must be in a regulated manner. These cells are like "mother cells" from which other cells are regenerated from. They have the ability to regenerate & repair damaged tissues in the body. These other cells that are re-generated aren't just the normal cells, but rather they are specialized kind of cells. Some quotas calls these regenerated cells 'daughter cells'.Stem cell therapy or treatment which is also known as the regenerative therapy (that is the generation of healthy cells to replace damaged or dead cells), is one that enhances the refurbishment or restoration of dysfunctional or damaged tissues so that they become more useful to the body, with the help of the stem cells. This book will enlighten you on the basics & rudiments of the stem cell therapeutic procedures, with all its contemporary benefits.