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Stem Cell Therapy For Osteoarthritis

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Stem Cell Therapy as an Alternative for Osteoarthritis of the Knee

Stem Cell Therapy as an Alternative for Osteoarthritis of the Knee Book
Author : Jessica Wornham
Publisher : Unknown
Release : 2020
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Stem Cell Therapy as an Alternative for Osteoarthritis of the Knee book written by Jessica Wornham, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Stem Cells for Osteoarthritis Volume 2

Stem Cells for Osteoarthritis Volume 2 Book
Author : Nathan Wei
Publisher : Unknown
Release : 2014-10-28
ISBN : 9781503017481
Language : En, Es, Fr & De

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Book Description :

Osteoarthritis is the most common form of arthritis... but like Rodney Dangerfield, it doesn't get much respect. The reason is that it is so hard to treat.The types of management techniques used haven't changed in almost forty years. Very few pharmaceutical and biotech companies are willing to tackle osteoarthritis because it is such a difficult task. The number of clinical trials involving new therapies for osteoarthritis is riddled with the bodies of the fallen.For those of us in clinical practice, it has been a frustrating experience... until now...The initial volume The Book On Stem Cells For Osteoarthritis was a compilation of articles I had written on the subject of mesenchymal stem cells in the earlier days of our experience with this technology. The impetus for the first volume was to provide readers instant access to all the articles I had written on the topic rather than having to click their way through the internet. While the first book- really a booklet- was received with a lot of enthusiasm, it was clear there was also a lot of repetitive information. Unfortunately, that is the nature of a compilation of articles... there is much repetitive information.I believe the key thing is that the information is good. It is understandable. And repetition is not necessarily a bad thing when it comes to understanding knee osteoarthritis and the options available for treatment. There have been new developments in our understanding of this condition, particularly when it comes to the knee. And that's exciting for those of us who are in the Boomer demographic.In this volume I also discuss other forms of knee pain that will shed light on how difficult the diagnosis can be in certain instances.I have also updated information on stem cell biology.As the reader might imagine, the science is constantly evolving. The same is true for the procedures themselves.If the goal is to delay or even eliminate the need for joint replacement, the optimal procedure for the application of stem cell therapy is going to go through a series of improvements with the passage of time.

Stem Cell Therapy for Osteoarthritis

Stem Cell Therapy for Osteoarthritis Book
Author : Yin Xiao
Publisher : Academic Press
Release : 2021-08-15
ISBN : 9780128219973
Language : En, Es, Fr & De

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Book Description :

Stem Cell Therapy for Osteoarthritis delivers state-of-the-art knowledge of current stem cell therapies for osteoarthritis. Current literature is dated or spread across many research articles. This volume will include different sources of adult stem cells, cell derived biological agents, stem cell derived exomes, secretion factors and more. In addition to covering current therapies and technologies, the authors summarize methodologies, applications and the inclusion/exclusion criteria. The authors are world-renown experts in the field and this book fills a gap in the market. Introduces the latest updates and technologies in stem cell therapy for osteoarthritis Covers mechanisms, stem cell-based products, clinical trials, current challenges and much more Written for academic researchers, to PhD students, medical doctors, including rheumatologists and orthopaedic surgeons, other physicians and nurses

Bone and Cartilage Regeneration

Bone and Cartilage Regeneration Book
Author : Phuc Van Pham
Publisher : Springer
Release : 2017-01-24
ISBN : 3319401440
Language : En, Es, Fr & De

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Book Description :

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Application of Stem Cells in Canine Osteoarthritis

Application of Stem Cells in Canine Osteoarthritis Book
Author : Shyamal Kanti Guha,Tarani Naskar
Publisher : LAP Lambert Academic Publishing
Release : 2015-04-14
ISBN : 9783659695612
Language : En, Es, Fr & De

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Book Description :

Stem cell therapy has emerged as a new direction in the field of regenerative medicine. Hundreds of workers throughout the world continue to refine and explore the role of bone marrow and cord blood stem cells for their regular use to solve hematological and immune mediated disorders since many years. Many of them are working to explore the uses of the different types of adult mesenchymal stem cells found in bone marrow and cord blood that could be corrected by replacing cells in the damaged tissues in their own lineages. In recent years stem cell research is being pursued in the hope of achieving major medical breakthroughs. Scientists are striving to create therapies that rebuild or replace damaged cells with tissues grown from stem cells and offer hope to people suffering from cancer, diabetes, cardiovascular disease, spinal-cord injuries, and many other neurodegenerative disorders. Both adult and embryonic stem cells may also provide a route for scientists to develop valuable new methods of drug discovery and testing.

Regenerative Medicine and Cell Therapy

Regenerative Medicine and Cell Therapy Book
Author : J. F. Stoltz
Publisher : IOS Press
Release : 2012
ISBN : 1614990751
Language : En, Es, Fr & De

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Book Description :

Most human tissues do not regenerate spontaneously. Cell therapy and tissue engineering, which involve collecting cells from either the patient or a donor and introducing them into injured tissues or organs, sometimes after modifying their properties, offer promising solutions for regenerative medicine. Indeed, so promising are these therapies that current research has shifted from organ growth to cell therapy. The range of therapeutic applications is wide, including cardiac insufficiency, atherosclerosis, cartilage defects, bone repair, burns, diabetes and liver or bladder regeneration.This book, whilst not covering all aspects

PRP standardisation cells therapies

PRP standardisation cells therapies Book
Author : Collectif
Publisher : Favre
Release : 2018-03-01
ISBN : 2828912086
Language : En, Es, Fr & De

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Book Description :

Une monographie (en anglais) consacrée au PRP (Plasma Riche en Plaquettes) et thérapies cellulaires : les applications médicales, la fabrication, le fonctionnement, la standardisation et les études menées à ce jour avec les résultats. La médecine régénérative englobe un large éventail de techniques ayant pour but de réparer, voire remplacer, les tissus endommagés ou âgés. Le plasma riche en plaquettes (PRP) autologue représente l'approche de médecine régénérative la plus simple. Cette technique est basée sur les capacités intrinsèques du corps humain à réparer une lésion tissulaire. L'intérêt croissant qu'elle suscite s'explique à la fois par le fait qu'elle représente une alternative sûre et naturelle à d'autres formes de traitement plus invasives et par les résultats prometteurs qu'elle a démontrés jusqu'à maintenant pour un grand nombre d'indications. Le plasma riche en plaquettes (abréviation PRP), ou plasma riche en facteurs de croissance (abréviation PRGF) est du plasma sanguin enrichi en plaquettes par une centrifugation. Le PRP est une source concentrée de plaquettes autologues. Il contient et relâche par dégranulation différents facteurs de croissance et cytokines capables de stimuler la régénération de certains tissus. Il est ainsi utilisé dans de nombreuses indications médicales et esthétiques. Si le PRP est en train de devenir un acteur incontournable dans le monde médical, certaines limitations liées à un manque de procédure standardisée pour sa préparation rendent difficile la comparaison entre les données cliniques disponibles. La technologie développée par Regen Lab SA s'impose actuellement comme la seule capable d'apporter une solution à ce défi de standardisation des préparations de cellules fraîches. Sur la base d'une expérience de plus de 10 ans, ce livre a été conçu par Regen Lab SA afin d'aider les professionnels impliqués dans la médecine régénérative à mieux comprendre et utiliser le PRP. Il est en en premier lieu destiné aux médecins qui exercent et conduisent des recherches dans des disciplines où les thérapies avec le PRP représentent une option thérapeutique, mais il s'adresse également à quiconque recherchant des informations fiables et à jour sur cette technologie. ----- In the 60's, a scientist called Doctor Leonard Hayflick (Wistar Institute, Philadelphia) carefully characterized the serial cultivation of primary human fibroblast cell by demonstrating that primary human cell strains have a limited replicative lifespan or "doubling potential", restricted to 40-50 divisions. This finding led to the hypothesis that oxidative damage could be partially responsible for limiting in vitro lifespan, consistent with the free radical hypothesis of aging. We now know that senescence in response to repeated passage occurs because of critical shortening of the telomeres. The Hayflick theory has been greatly reconsidered by the observations from the INSERM group of Dr Barlovatz-Meimon published in 2003 in Paris regarding in vivo (i.e. on the patient himself) cell growth. These studies hypothesized that the fibroblasts may reach a 2 to 3 log growth, meaning that they could potentially undergo up to 500 to 5'000 cell divisions. Our GMP class II and III medical devices fully guarantee the patient's safety because they are non-pyrogenic. Moreover, our manufacture process respects a full compliance with the new European Medical Device Regulation (MDR) June 2017, FDA (USA), and CFDA Regulations. For all these reasons, we believe that we bring to the medical community a powerful and reliable tool to standardize PRP preparations and thus future cell therapy clinical outcomes.

Towards Cell Therapy for Osteoarthritis

Towards Cell Therapy for Osteoarthritis Book
Author : Anonim
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Towards Cell Therapy for Osteoarthritis book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Current Therapy in Equine Medicine

Current Therapy in Equine Medicine Book
Author : Norman Edward Robinson,Kim A. Sprayberry
Publisher : Elsevier Health Sciences
Release : 2009
ISBN : 1416054758
Language : En, Es, Fr & De

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Book Description :

Stay up-to-date on the latest advances and current issues in equine medicine with this handy reference for the busy equine practitioner, large animal veterinarian, or student. This edition of Current Therapy in Equine Medicine brings you thorough coverage and expert advice on selected topics in areas that have seen significant advances in the last 5 years. Content emphasizes the practical aspects of diagnosis and treatment and provides details for therapeutic regimens. Arranged primarily by body system, the text also features sections on infectious diseases, foal diseases, nutrition, and toxicology. With this cutting-edge information all in one reliable source, you'll increase your awareness of key therapies in less time. Focuses on the latest therapy for equine diseases, emphasizing detailed discussions and the most reliable and current information. Organized approach to important problems brings you up-to-date, practical information organized by organ system. Concise, easy-to-read format saves you time; most articles provide essential information in 2 to 5 pages. Renowned group of contributors share their expertise on the timely topics you need to know about. Photos enhance information. Line drawings illustrate important concepts. NEW! Emerging topics include issues such as disinfection in equine hospitals; complimentary modalities to traditional medicine; chemotherapy for oncological diseases; and protecting yourself with medical records. Each section has NEW topics including medical management of critically ill foals in the field; oral cavity masses; radiology of sinuses and teeth; biochemical tests for myocardial injury; protozoal myeloencephalitis update; management of bladder uroliths; skin grafting; managing the high-risk pregnancy; shock wave therapy; and more!

Stem Cell Transplantation for Autoimmune Diseases and Inflammation

Stem Cell Transplantation for Autoimmune Diseases and Inflammation Book
Author : Phuc Van Pham
Publisher : Springer
Release : 2019-08-13
ISBN : 3030234215
Language : En, Es, Fr & De

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Book Description :

This book introduces many new technologies and clinical applications of hematopoietic stem cells and mesenchymal stem cell transplantation for the treatment of autoimmune diseases and inflammatory diseases. Presented in two parts, Part 1 focuses on stem cell therapies for autoimmune disease treatment; Part 2 focuses on stem cell therapies and their application in the treatment of common inflammatory diseases, including chronic knee osteoarthritis, chronic obstructive pulmonary disease, liver cirrhosis, Crohn's Disease, Multiple Sclerosis, and more. This book is an essential source for all advanced students and researchers involved with these diseases, stem cells, or both. Stem Cell Transplantation for Autoimmune Diseases and Inflammation and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine, or tissue engineering as well as cancer or genetics research.

Stem Cells

Stem Cells Book
Author : Rex Turner
Publisher : Unknown
Release : 2016-07-27
ISBN : 9781632414120
Language : En, Es, Fr & De

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Book Description :

Stem cells are found in multicellular organisms. They have two broad categories - embryonic stem cells and adult stem cells. They are generally found in undifferentiated form and can be transformed into specialized cells. In adults, they act as a repair system of the body. These cells are frequently used in medical therapies such as bone marrow transplant, etc. The viability of stem cell therapy is being investigated to treat diseases such as cancer, diabetes, rheumatoid arthritis, osteoarthritis, vision impairment, parkinson's disease, impaired hearing, etc. This book covers in detail some existent theories and innovative concepts revolving around developments in the field of stem cell research. It is an upcoming field of medical science that has undergone rapid development over the past few decades. This text aims to bring forth studies related to all the significant aspects of stem cells along with technological progress that will have future implications. For all those who are interested in this area of study, this book can prove to be an essential guide.

Controversies in Rheumatology An Issue of Rheumatic Disease Clinics of North America

Controversies in Rheumatology An Issue of Rheumatic Disease Clinics of North America Book
Author : Jonathan Kay,Sergio Schwartzman
Publisher : Elsevier Health Sciences
Release : 2019-07-16
ISBN : 0323698298
Language : En, Es, Fr & De

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Book Description :

Guest edited by Drs. Jonathan Kay and Sergio Schwartzman, this issue of Rheumatic Disease Clinics will cover Controversies in Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles explore several questions, including, but not limited to: Is triple therapy or methotrexate plus a biologic the initial treatment of choice for RA patients; Is hypo or hyper-uricemia a risk requiring treatment for cardiac morbidity and mortality; Are there benefits and risks to biosimilars from a patient perspective; Should platelet-rich plasma be used to treat osteoarthritis; Is there a role for stem cell therapy to treat cartilage defects in osteoarthritis; Should any rheumatology patient, today, be treated with bone marrow ablation and stem cell transplantation; Is there effective prevention, prophylaxis, or treatment for CPPD arthritis; Is fibromyalgia a psychiatric disease or a pain syndrome; Should cyclophosphamide still be used to treat ANCA-associated vasculitis; Does methotrexate have a place in the treatment of psoriatic arthritis; Should hydroxychloroquine dosing be limited because of potential ocular toxicity; and Should generalized immunosuppression or targeted organ treatment be the best principle for overall management of SLE.

Update on Mesenchymal and Induced Pluripotent Stem Cells

Update on Mesenchymal and Induced Pluripotent Stem Cells Book
Author : Khalid Ahmed Al-Anazi
Publisher : BoD – Books on Demand
Release : 2020-04-22
ISBN : 1789238072
Language : En, Es, Fr & De

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Book Description :

This book represents an updated overview on selected topics related to mesenchymal stem cells as well as induced pluripotent stem cells. The book is divided into three main sections that cover several topics including: sources of both stem cell types, their preparation and general properties, as well as their therapeutic indications and clinical utilization with particular attention given to their use in infectious diseases, osteoarthritis, as well as immunological disorders.

Early Osteoarthritis

Early Osteoarthritis Book
Author : Christian Lattermann,Henning Madry,Norimasa Nakamura,Elizaveta Kon
Publisher : Springer Nature
Release : 2021-10-09
ISBN : 3030794857
Language : En, Es, Fr & De

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Book Description :

Early osteoarthritis is novel topic for orthopedic surgeons and its process begins immediately after joint injury. The mechanical restoration of the joint surface or ligamentous stability is not sufficient to restore the homeostatic environment in the joint, and this leads to osteoarthritis, despite mechanical stability and alignment. This book sheds light on the various mechanisms and systems involved in the gradual decline of the injured joint toward manifest osteoarthritis. Published in collaboration with ISAKOS, this volume appeals to all stakeholders in surgical orthopaedics and sports medicine.

Stem Cell Processing

Stem Cell Processing Book
Author : Phuc Van Pham
Publisher : Springer
Release : 2016-10-18
ISBN : 3319400738
Language : En, Es, Fr & De

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Book Description :

This invaluable resource delineates procedures for development and use of stem cells in the laboratory and explores the potential for clinical applications. The text discusses mesenchymal stem cell isolation, isolation of adipose derived stem cells, new trends of induced pluripotent stem cells in disease treatment, cord blood banking, future directions of the discussed therapies and much more. The chapters are contributed by preeminent scientists in the field and present a comprehensive picture of stem cell processes, from development in the laboratory to effects and side-effects of clinical application. Stem Cell Processing and the other books in the Stem Cells in Clinical Applications series, edited by Dr. Phuc Van Pham, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Stem Cell Dependent Therapies

Stem Cell Dependent Therapies Book
Author : Gerhard Gross,Thomas Häupl
Publisher : Walter de Gruyter
Release : 2013-10-29
ISBN : 3110298309
Language : En, Es, Fr & De

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Book Description :

Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.

Advances in Stem Cells

Advances in Stem Cells Book
Author : Ashton Silk
Publisher : Unknown
Release : 2020-09-08
ISBN : 9781632418678
Language : En, Es, Fr & De

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Book Description :

Stem cells are the cells that differentiate into other cells and divide upon self-renewal to produce more stem cells. There are two types of stem cells, embryonic stem cells and adult stem cells. Progenitor cells and stem cells serve as a repair system by replenishing adult tissues. In the developing embryo, stem cells differentiate into specialized cells- endoderm, ectoderm and mesoderm, and also maintain the normal turnover of regenerative organs like skin, blood and intestinal tissues. Embryonic stem cells are a theoretically potential source for the development of regenerative medicine and tissue replacement. Adult stem cells can be acquired from adipose tissue, blood and bone marrow, as well as from the blood of the umbilical cord after birth. They are used in medical therapies such as in bone marrow transplantation. They can also be artificially grown and differentiated into specialized cells. Stem cell therapy helps to treat and prevent diseases or conditions. Some of the diseases where stem cell treatment holds potential include Parkinson's disease, diabetes, osteoarthritis, spinal cord injury repair, rheumatoid arthritis, cancer, amyotrophic lateral sclerosis, etc. This book is a valuable compilation of topics, ranging from the basic to the most complex advances in stem cells. It explores all the important aspects of stem cell therapy in the present day scenario. Scientists and students actively engaged in this field will find this book full of crucial and unexplored concepts.

Orthopedic Stem Cell Surgery

Orthopedic Stem Cell Surgery Book
Author : Jeffrey N. Weiss
Publisher : Springer Nature
Release : 2021
ISBN : 3030732991
Language : En, Es, Fr & De

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Book Description :

This book is a concise guide that provides an easy to follow template for other physicians to develop similar stem cell based treatments within their specialty. It identifies and summarizes the current world-wide orthopedic stem cell trials. Organized into three sections, Orthopedic Stem Cell Surgery presents clinical studies that examine the procedures for setting up and implementing stem cell surgery within the specialty of orthopedics. Chapters maintain an accessible narrative while also addressing complex studies related to orthopedic stem cell surgery. A sister text to the recently published, Retinal and Optic Nerve Stem Cell Surgery, and Neurologic Stem Cell Surgery this expertly written book examines critical Institutional Review Board (IRB) approved studies.

The Regeneration Promise The Facts behind Stem Cell Therapies

The Regeneration Promise  The Facts behind Stem Cell Therapies Book
Author : Peter Hollands
Publisher : Bentham Science Publishers
Release : 2020-12-03
ISBN : 981148211X
Language : En, Es, Fr & De

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Book Description :

The Regeneration Promise is a reader-friendly guide to the world of regenerative medicine and stem cell technology. It covers the history of stem cell technology as a general introduction to the subject and then continues with a description of the many known types of stem cells and how these can potentially be used to treat disease. The author explains the pros and cons of using stem cell technology to treat patients in simple and factual terms throughout the book while clarifying many stem cell myths. There is valuable advice for people considering undergoing stem cell therapy and also for those who are considering stem cell storage such as umbilical cord blood storage at the birth of a baby. The book also covers information on current research in stem cell technology and how this may be useful in the clinic, as promising regenerative medicine treatments emerge in the near future. The simple use of language with a clear explanation of scientific terms, where applicable, makes this book an accessible source of information for anyone interested in enhancing their general knowledge about regenerative medicine when considering such treatment options and understanding the debate surrounding stem cell technology and its use in disease therapy.

Orthobiologics

Orthobiologics Book
Author : Giuseppe Filardo,Bert R. Mandelbaum,George F. Muschler,Scott A. Rodeo,Norimasa Nakamura
Publisher : Springer Nature
Release : 2021-12-02
ISBN : 3030847446
Language : En, Es, Fr & De

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Book Description :

This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.