Skip to main content

Stem Cell Innovation In Health Disease

In Order to Read Online or Download Stem Cell Innovation In Health Disease Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Stem Cell Innovation in Health Disease The Lung Volume 2

Stem Cell Innovation in Health   Disease  The Lung  Volume 2 Book
Author : Ahmed H.K. El-Hashash
Publisher : Academic Press
Release : 2021-06-01
ISBN : 0128212128
Language : En, Es, Fr & De

GET BOOK

Book Description :

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the lung

Stem Cell Innovation in Health Disease The Lung Volume 2

Stem Cell Innovation in Health   Disease  The Lung  Volume 2 Book
Author : Ahmed El-Hashash
Publisher : Academic Press
Release : 2021-06-10
ISBN : 0128212071
Language : En, Es, Fr & De

GET BOOK

Book Description :

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the lung

The Intestine

The Intestine Book
Author : Ahmed El-Hashash,Eiman Abdel Meguid
Publisher : Academic Press
Release : 2021-06-15
ISBN : 0128212713
Language : En, Es, Fr & De

GET BOOK

Book Description :

The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the intestine

Stem Cell Therapies

Stem Cell Therapies Book
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy
Publisher : National Academies Press
Release : 2014-06-18
ISBN : 0309303036
Language : En, Es, Fr & De

GET BOOK

Book Description :

Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson's disease, diabetes, and spinal cord injury. Clinical trials of stem cell treatments are under way in countries around the world, but the evidence base to support the medical use of stem cells remains limited. Despite this paucity of clinical evidence, consumer demand for treatments using stem cells has risen, driven in part by a lack of available treatment options for debilitating diseases as well as direct-to-consumer advertising and public portrayals of stem cell-based treatments. Clinics that offer stem cell therapies for a wide range of diseases and conditions have been established throughout the world, both in newly industrialized countries such as China, India, and Mexico and in developed countries such as the United States and various European nations. Though these therapies are often promoted as being established and effective, they generally have not received stringent regulatory oversight and have not been tested with rigorous trials designed to determine their safety and likely benefits. In the absence of substantiated claims, the potential for harm to patients - as well as to the field of stem cell research in general - may outweigh the potential benefits. To explore these issues, the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research held a workshop in November 2013. Stem Cell Therapies summarizes the workshop. Researchers, clinicians, patients, policy makers, and others from North America, Europe, and Asia met to examine the global pattern of treatments and products being offered, the range of patient experiences, and options to maximize the well-being of patients, either by protecting them from treatments that are dangerous or ineffective or by steering them toward treatments that are effective. This report discusses the current environment in which patients are receiving unregulated stem cell offerings, focusing on the treatments being offered and their risks and benefits. The report considers the evidence base for clinical application of stem cell technologies and ways to assure the quality of stem cell offerings.

Joint and Bone

Joint and Bone Book
Author : Deming Jiang
Publisher : Academic Press
Release : 2022-09-15
ISBN : 9780323919388
Language : En, Es, Fr & De

GET BOOK

Book Description :

Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside. Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases. Provides cutting-edge research needed to understand stem cell functions in joint and bone diseases Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in the joint and bone

The Delivery of Regenerative Medicines and Their Impact on Healthcare

The Delivery of Regenerative Medicines and Their Impact on Healthcare Book
Author : Catherine Prescott,Dame Julia Polak
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1439836078
Language : En, Es, Fr & De

GET BOOK

Book Description :

Now that prohibitions against stem cell research are relaxing, it is time for the field to move forward with the advances that promise to eliminate so much human suffering. However, it would be naïve to ignore the fact that regenerative medicines pose a whole new set of challenges to an industry sector that for decades has geared itself to the development and delivery of traditional pharmaceuticals. Still, significant strides are being made. Unique in its focus, The Delivery of Regenerative Medicines and Their Impact on Healthcare delves into material not included in other books. Edited by Dr. Catherine Prescott and Professor Dame Julia Polak, two of the most respected authorities in stem cell research and the business of regenerative medicine, this text presents original firsthand accounts of experts from around the globe. Professor Polak starts by summarizing the progress made and the challenges currently facing the field both as a science and an emerging industry. This is followed by topics relevant to regulators, insurers, and investors as well as pharmaceutical and biotech researchers. Offering innovative insight on topics rarely covered, this volume: Details various innovative investment models Offers a detailed overview of cell-based products and therapeutic stem cell technologies Examines concerns over safeguarding intellectual property Looks at evolving regulations in the U.S. and Europe Discusses insurance and risk management and the establishment of reimbursement parameters This book reaches out to inform a wide audience across government, industry, and academia. It goes beyond the usual discussions to help invigorate the dialogue and present solutions that must occur at the crossroads of technology and commerce for regenerative medicines to realize their promise.

Stem Cell Tourism and the Political Economy of Hope

Stem Cell Tourism and the Political Economy of Hope Book
Author : Alan Petersen,Megan Munsie,Claire Tanner,Casimir MacGregor,Jane Brophy
Publisher : Springer
Release : 2017-01-12
ISBN : 1137470437
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book provides a unique and innovative perspective on the controversial phenomenon of ‘stem cell tourism’. A growing number of patients are embarking on stem cell treatments that are clinically unproven and yet available in clinics and hospitals around the world. The authors offer a cutting-edge multi-dimensional perspective on this complex and rapidly changing phenomenon, including an analysis of the experiences of those who have undertaken or have contemplated undertaking a stem cell treatment, as well as examination of the views of those who undertake research or advise on or provide stem cell treatments. Developing the concept of ‘the political economy of hope’, and referencing case studies of the stem cell treatment market in China, Germany, and Australia, this book argues for a reframing of ‘stem cell tourism’ to understand why patients and families pursue these treatments and whether authorities’ concerns are justified and whether their responses are appropriate and proportionate to the alleged risks.

Gendered Innovation in Health and Medicine

Gendered Innovation in Health and Medicine Book
Author : Londa Schiebinger,Ineke Klinge
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Abstract: "'Gendered Innovations' integrates sex and gender analysis into all phases of biomedical and health research to assure excellence and quality in outcomes. This article reports on the interdisciplinary, international collaboration that produced: 1) state-of-the-art methods of sex and gender analysis for health and medicine; and 2) case studies to illustrate how gender analysis leads to discovery in biomedicine and better outcomes in health research: osteoporosis research in men, the genetics of sex determination, heart disease in women, stem cell research, animal research, nutrigenomics and degendering knee implants. The article concludes with a short review of policy at the Canadian, US, and European institutes of health, medical curricula, and policies for peer-reviewed journals in relation to reporting sex/gender analysis in research." (Autorenreferat)

Medical Innovation and Disease Burden

Medical Innovation and Disease Burden Book
Author : Sobin George
Publisher : Cambridge University Press
Release : 2021-02-28
ISBN : 1108968228
Language : En, Es, Fr & De

GET BOOK

Book Description :

Striking the right balance between public health priorities and health innovation is a critical policy challenge for India given their mutually conflicting nature and interests. India has a huge burden of diseases implicated by a gamut of health problems including the uneven distribution of demographic and epidemiological transition, threat of new infectious disease pandemic like COVID 19, increasing privatisation of healthcare, low affordability to life saving medicines and most importantly the escalating healthcare expenditure coupled with poor financial risk protection. The central question that the book addresses is whether health innovation in India is sensitive to the public health needs and priorities. It unearths the overriding issues related to responsiveness and equity in India's health innovation. The book highlights the need for a responsible innovation framework for India that balances the priorities of public health and the industry goals.

New Technologies in Health Care

New Technologies in Health Care Book
Author : A. Webster
Publisher : Springer
Release : 2006-07-25
ISBN : 0230506046
Language : En, Es, Fr & De

GET BOOK

Book Description :

The first detailed and comprehensive analysis of the implications of new health technologies for society, the delivery of health care, and the very meaning of health itself. It is based on new, critical social science research integrated according to core themes, making it accessible and engaging to both students and researchers.

Rapid Medical Countermeasure Response to Infectious Diseases

Rapid Medical Countermeasure Response to Infectious Diseases Book
Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Global Health,Board on Health Sciences Policy,Forum on Microbial Threats,Forum on Drug Discovery, Development, and Translation,Forum on Medical and Public Health Preparedness for Catastrophic Events
Publisher : National Academies Press
Release : 2016-03-12
ISBN : 0309378613
Language : En, Es, Fr & De

GET BOOK

Book Description :

Emerging infectious disease threats that may not have available treatments or vaccines can directly affect the security of the world's health since these diseases also know no boundaries and will easily cross borders. Sustaining public and private investment in the development of medical countermeasures (MCMs) before an emerging infectious disease becomes a public health emergency in the United States has been extremely challenging. Interest and momentum peak during a crisis and wane between events, and there is little interest in disease threats outside the United States until they impact people stateside. On March 26 and 27, 2015, the Institute of Medicine convened a workshop in Washington, DC to discuss how to achieve rapid and nimble MCM capability for new and emerging threats. Public- and private-sector stakeholders examined recent efforts to prepare for and respond to outbreaks of Ebola Virus Disease, pandemic influenza, and coronaviruses from policy, budget, and operational standpoints. Participants discussed the need for rapid access to MCM to ensure national security and considered strategies and business models that could enhance stakeholder interest and investment in sustainable response capabilities. This report summarizes the presentations and discussions from this workshop.

Encyclopedia of Stem Cell Research

Encyclopedia of Stem Cell Research Book
Author : Anonim
Publisher : SAGE
Release : 2008
ISBN : 141295908X
Language : En, Es, Fr & De

GET BOOK

Book Description :

"Provides an understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field"--From publisher description.

Mesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases Book
Author : Ahmed H.K. El-Hashash
Publisher : Academic Press
Release : 2020-01-07
ISBN : 0128205334
Language : En, Es, Fr & De

GET BOOK

Book Description :

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Stem Cells

Stem Cells Book
Author : Nicole Arrighi
Publisher : Elsevier
Release : 2018-03-27
ISBN : 0081025882
Language : En, Es, Fr & De

GET BOOK

Book Description :

Stem Cells: Therapeutic Innovations under Control traces the discovery of stem cells and induced pluripotent cells. It establishes the link between knowledge about cell development and tissue engineering, and presents perspectives in regenerative medicine. Cell proliferation and tissue architecture open up unexpected applications in tissue engineering, with the development of tissues or organs. In this context emerges the need to address the issue of bioethics and regulatory considerations. Because stem cells can multiply and differentiate into cells specific to a particular tissue or organ, they represent vast potential in the health field. Traces the discovery of stem cells to link knowledge of cell development with tissue engineering Presents prospects in regenerative medicine Establishes the link between knowledge about cell development and tissue engineering

Safety Ethics and Regulations

Safety  Ethics and Regulations Book
Author : Phuc Van Pham,Achim Rosemann
Publisher : Springer
Release : 2017-08-12
ISBN : 3319591657
Language : En, Es, Fr & De

GET BOOK

Book Description :

This invaluable resource discusses the saftey, ethics, and regulations of developing stem cell clinical applications. Each chapter is contributed by a preeminent scientist in the field and covers such topics as clinical safety of stem cell gene therapy, the patentability of hESC technologies, international guidelines, challenges to international stem cell clinical trials, worldwide regulations including in emerging markets like China and Taiwan. Saftey, Ethics, and Regulations and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Stem Cell Research and the Collaborative Regulation of Innovation

Stem Cell Research and the Collaborative Regulation of Innovation Book
Author : Sarah Devaney
Publisher : Routledge
Release : 2013-12-13
ISBN : 1136014403
Language : En, Es, Fr & De

GET BOOK

Book Description :

Hopes are high that stem cell (SC) research will lead to treatments and cures for some of the most serious diseases affecting humankind today. SC science has been used in a treatment setting in the replacement of patients’ windpipes and in restoring sight to patients who were blind in one eye and in future it is hoped that when the body is injured it will be able to be stimulated to produce those types of SCs necessary to repair the particular damage caused. In the meantime, research into specific treatments for a wide range of serious conditions is being undertaken including Alzheimer’s disease, cancer, and diabetes. The book considers the regulatory governance of stem cell research, setting out a readily understandable account of the science and the challenges it poses for regulators as the research is increasingly being clinically applied. It provides a critical account of those elements of a regulatory system which will be required for any jurisdiction aiming to facilitate innovative and productive SC research while maintaining appropriate ethical and legal controls. The book addresses the specific failings in the current regulatory approach to SC research in the UK and goes on to look at the regulatory approaches in the US. The book systematically analyses the roles and responsibilities of the three key participants who collaborate in this process: regulators, scientists and tissue providers, arguing that a regulatory system which fails to recognise and facilitate the vital role which each of these three groups plays runs the risk of impairing the chances of the hopes for SC research being realised. The book places a particular emphasis on ensuring that those who contribute their bodily tissues to this endeavour are treated fairly, involving a recognition that their tissues are their property.

Public Private Partnerships as Drivers of Innovation in Healthcare 2nd Edition

Public Private Partnerships as Drivers of Innovation in Healthcare  2nd Edition Book
Author : Hilde Stevens,Michel Goldman
Publisher : Frontiers Media SA
Release : 2020-08-04
ISBN : 2889639452
Language : En, Es, Fr & De

GET BOOK

Book Description :

Multi-stakeholder collaborations involving partners from public and private sectors are essential to address global health challenges and to move precision medicine forward. This eBook assembles a collection of papers which either illustrate recent achievements or discuss new perspectives offered by public-private partnerships in healthcare. Publisher’s note: In this 2nd edition, the following article has been added: Laverty H and Meulien P (2019) The Innovative Medicines Initiative −10 Years of Public-Private Collaboration. Front. Med. 6:275. doi: 10.3389/fmed.2019.00275

Science Technology on Public Health in China A Roadmap to 2050

Science   Technology on Public Health in China  A Roadmap to 2050 Book
Author : Kaixian Chen,Qishui Lin,Jiarui Wu
Publisher : Springer Science & Business Media
Release : 2010-08-09
ISBN : 3642053386
Language : En, Es, Fr & De

GET BOOK

Book Description :

As one of the eighteen field-specific reports comprising the comprehensive scope of the strategic general report of the Chinese Academy of Sciences, this sub-report addresses long-range planning for developing science and technology in the field of public health. They each craft a roadmap for their sphere of development to 2050. In their entirety, the general and sub-group reports analyze the evolution and laws governing the development of science and technology, describe the decisive impact of science and technology on the modernization process, predict that the world is on the eve of an impending S&T revolution, and call for China to be fully prepared for this new round of S&T advancement. Based on the detailed study of the demands on S&T innovation in China's modernization, the reports draw a framework for eight basic and strategic systems of socio-economic development with the support of science and technology, work out China's S&T roadmaps for the relevant eight basic and strategic systems in line with China's reality, further detail S&T initiatives of strategic importance to China's modernization, and provide S&T decision-makers with comprehensive consultations for the development of S&T innovation consistent with China's reality. Supported by illustrations and tables of data, the reports provide researchers, government officials and entrepreneurs with guidance concerning research directions, the planning process, and investment. Founded in 1949, the Chinese Academy of Sciences is the nation's highest academic institution in natural sciences. Its major responsibilities are to conduct research in basic and technological sciences, to undertake nationwide integrated surveys on natural resources and ecological environment, to provide the country with scientific data and consultations for government's decision-making, to undertake government-assigned projects with regard to key S&T problems in the process of socio-economic development, to initiate personnel training, and to promote China's high-tech enterprises through its active engagement in these areas.

Opportunities and Challenges in Digital Healthcare Innovation

Opportunities and Challenges in Digital Healthcare Innovation Book
Author : Sandhu, Kamaljeet
Publisher : IGI Global
Release : 2020-06-26
ISBN : 1799832759
Language : En, Es, Fr & De

GET BOOK

Book Description :

Digital health has faced obstacles from poor IT systems implementation to lack of consumer acceptance. Very little is known about the management, development, and design of digital health projects, the level of IT adoption, and the role of digital leadership that is needed to successfully drive health projects. Digital health, if successfully implemented, offers tremendous opportunities in health data analytics for consumers of health services and service providers that include health information portability, personalization of health information by consumers, easy access and usefulness of health information, and better management of electronic data records by health institutions and the government. Research suggests that despite assurances provided to consumers, digital information security and digital health innovation have been a challenge and are only slowly being accepted. Opportunities and Challenges in Digital Healthcare Innovation is an innovative research publication that identifies digital health innovation opportunities and obstacles and proposes frameworks and conceptual models for digital health innovation that empowers consumers of digital health to use the information to make informed decisions and choices. Highlighting topics such as data analytics, health regulations, and telehealth, this book is ideal for IT consultants, medical software developers, data scientists, hospital administrators, medical practitioners, policymakers, academicians, researchers, and students.

Global Perspectives on Stem Cell Technologies

Global Perspectives on Stem Cell Technologies Book
Author : Aditya Bharadwaj
Publisher : Springer
Release : 2017-10-30
ISBN : 3319637878
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book takes as its point of departure a humble cell lying on the intersection of ideas as diverse and yet interlaced as life, knowledge, commerce, governance, and ethics. It seeks to deepen the understanding of stem cell entities and the concerns, hopes, and aspirations that shape and make them viable therapeutic entities in the context of rapid globalization. Several key intersections between individual, group, and institutional relationships have become central to locating and debating the production of stem cells today. This edited collection addresses three overarching concerns: regenerating the notion of ethics, the emerging therapeutic horizons, and the position of the patient. As a whole this book seeks to explain how stem cells are accommodated, contested, and used in contemporary India and around the globe through an informed unpacking of issues underpinning contestation and promotion bestriding these technological developments. The authors offer a truly multi-disciplinary perspective, stimulating conversation between the social sciences, biological sciences and the patient. The concerns expressed and highlighted by these conversations are embedded in a vast geo-political expanse stretching from India to Euro-America and will be of great interest to academics and practitioners across fields including science technology studies, medicine and international development.