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Statistical Parametric Mapping

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Statistical Parametric Mapping The Analysis of Functional Brain Images

Statistical Parametric Mapping  The Analysis of Functional Brain Images Book
Author : William D. Penny,Karl J. Friston,John T. Ashburner,Stefan J. Kiebel,Thomas E. Nichols
Publisher : Elsevier
Release : 2011-04-28
ISBN : 0080466508
Language : En, Es, Fr & De

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Book Description :

In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. An essential reference and companion for users of the SPM software Provides a complete description of the concepts and procedures entailed by the analysis of brain images Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data Stands as a compendium of all the advances in neuroimaging data analysis over the past decade Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes Structured treatment of data analysis issues that links different modalities and models Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible

Statistical Parametric Mapping

Statistical Parametric Mapping Book
Author : Karl J. Friston
Publisher : Elsevier
Release : 2007
ISBN : 0123725607
Language : En, Es, Fr & De

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Book Description :

Provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development.

Empirical Validation of Statistical Parametric Mapping for Group Imaging of Fast Neural Activity Using Electrical Impedance Tomography

Empirical Validation of Statistical Parametric Mapping for Group Imaging of Fast Neural Activity Using Electrical Impedance Tomography Book
Author : N.A
Publisher :
Release : 2016
ISBN :
Language : En, Es, Fr & De

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Book Description :

Abstract: Electrical impedance tomography (EIT) allows for the reconstruction of internal conductivity from surface measurements. A change in conductivity occurs as ion channels open during neural activity, making EIT a potential tool for functional brain imaging. EIT images can have >10 000 voxels, which means statistical analysis of such images presents a substantial multiple testing problem. One way to optimally correct for these issues and still maintain the flexibility of complicated experimental designs is to use random field theory. This parametric method estimates the distribution of peaks one would expect by chance in a smooth random field of a given size. Random field theory has been used in several other neuroimaging techniques but never validated for EIT images of fast neural activity, such validation can be achieved using non-parametric techniques. Both parametric and non-parametric techniques were used to analyze a set of 22 images collected from 8 rats. Significant group activations were detected using both techniques (corrected p

Human Brain Function

Human Brain Function Book
Author : Karl J. Friston,Christopher D. Frith,Raymond J. Dolan,Cathy J. Price,Semir Zeki,John T. Ashburner,William D. Penny
Publisher : Elsevier
Release : 2004-01-26
ISBN : 9780080472959
Language : En, Es, Fr & De

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Book Description :

This updated second edition provides the state of the art perspective of the theory, practice and application of modern non-invasive imaging methods employed in exploring the structural and functional architecture of the normal and diseased human brain. Like the successful first edition, it is written by members of the Functional Imaging Laboratory - the Wellcome Trust funded London lab that has contributed much to the development of brain imaging methods and their application in the last decade. This book should excite and intrigue anyone interested in the new facts about the brain gained from neuroimaging and also those who wish to participate in this area of brain science. * Represents an almost entirely new book from 1st edition, covering the rapid advances in methods and in understanding of how human brains are organized * Reviews major advances in cognition, perception, emotion and action * Introduces novel experimental designs and analytical techniques made possible with fMRI, including event-related designs and non-linear analysis

The Oxford Handbook of Quantitative Methods Vol 2 Statistical Analysis

The Oxford Handbook of Quantitative Methods  Vol  2  Statistical Analysis Book
Author : Todd D. Little
Publisher : Oxford University Press
Release : 2013-02-01
ISBN : 0199934908
Language : En, Es, Fr & De

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Book Description :

Research today demands the application of sophisticated and powerful research tools. Fulfilling this need, The Oxford Handbook of Quantitative Methods is the complete tool box to deliver the most valid and generalizable answers to todays complex research questions. It is a one-stop source for learning and reviewing current best-practices in quantitative methods as practiced in the social, behavioral, and educational sciences. Comprising two volumes, this handbook covers a wealth of topics related to quantitative research methods. It begins with essential philosophical and ethical issues related to science and quantitative research. It then addresses core measurement topics before delving into the design of studies. Principal issues related to modern estimation and mathematical modeling are also detailed. Topics in the handbook then segway into the realm of statistical inference and modeling with chapters dedicated to classical approaches as well as modern latent variable approaches. Numerous chapters associated with longitudinal data and more specialized techniques round out this broad selection of topics. Comprehensive, authoritative, and user-friendly, this two-volume set will be an indispensable resource for serious researchers across the social, behavioral, and educational sciences.

Brain Mapping The Methods

Brain Mapping  The Methods Book
Author : Arthur W. Toga,John C. Mazziotta
Publisher : Academic Press
Release : 2002-10-09
ISBN : 9780126930191
Language : En, Es, Fr & De

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Book Description :

The number of scientists and laboratories involved with brain mapping is increasing exponentially; and the second edition of this comprehensive reference has also grown much larger than the first (published in 1996), including, for example, five chapters on structural and functional MRI where the fi

Neuroscience Databases

Neuroscience Databases Book
Author : Rolf Kötter
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461510791
Language : En, Es, Fr & De

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Book Description :

Neuroscience Databases: A Practical Guide is the first book providing a comprehensive overview of these increasingly important databases. This volume makes the results of the Human Genome Project and other recent large-scale initiatives in the neurosciences available to a wider community. It extends the scope of bioinformatics from the molecular to the cellular, microcircuitry and systems levels, dealing for the first time with complex neuroscientific issues and leading the way to a new culture of data sharing and data mining necessary to successfully tackle neuroscience questions. Aimed at the novice user who wants to access the data, it provides clear and concise instructions on how to download the available data sets and how to use the software with a minimum of technical detail with most chapters written by the database creators themselves.

Computing Brain Activity Maps from FMRI Time Series Images

Computing Brain Activity Maps from FMRI Time Series Images Book
Author : Gordon E. Sarty
Publisher : Cambridge University Press
Release : 2007
ISBN : 9780521868266
Language : En, Es, Fr & De

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Book Description :

A review of the methods used for analyzing fMRI data, with mathematical outlines of how each method works, and the software available for developing the data. Aimed at graduate students and research investigators.

Explorative Analysis of IPA SPECT Data Through Statistical Inference for an Automated Diagnosis of Glioma Tumor

Explorative Analysis of IPA   SPECT Data Through Statistical Inference for an Automated Diagnosis of Glioma Tumor Book
Author : N.A
Publisher :
Release : 2018
ISBN :
Language : En, Es, Fr & De

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Book Description :

Abstract : Purpose: The identification of a brain tumor imaged with PET or SPECT is usually performed with visual inspection of an expert medical clinician. However an automated diagnostic of such images hasn't been established or applied. In this study, we explored the possibility of establishing an automated statistical analysis for the diagnosis of glioma by means of IPA‐SPECT data. Methods: On the basis of a dataset of 100 patients that have undergone MRI and IPA‐SPECT acquisition, in this work, we identify an automated workflow. Three different approaches were explored: I. statistical non‐parametric mapping analysis (SnPM), II. statistical non‐parametric analysis with an increased number of permutations due to sign‐flipping function (PALM) and III. statistical parametric analysis (SPM). The automated methods were compared with the visual inspection. Results: The study proved PALM and SPM approaches to have a high diagnostic power. Compared to the parametric methods, the non‐parametric method is the mathematically correct approach for the problem in question. If we take the high resolution structural MRI information into account, the diagnostic power of PALM was not significantly inferior to the visual inspection ( P =0.5150), showing an area under the ROC curve (AUC) smaller only by less than 3%. Conclusions: The automated diagnostic method based on statistical inference, here applied to diagnose glioma tumors in IPA‐SPECT data, seems to be a promising tool that can support the visual investigation in nuclear medicine. Moreover in the foreseeable future, the presented methodology has a big potential in various application like localization of active tumor tissues in surgical resection or stereotactic radiosurgery.

The Oxford Handbook of Quantitative Methods in Psychology Vol 2

The Oxford Handbook of Quantitative Methods in Psychology  Vol  2 Book
Author : Todd D. Little
Publisher : Oxford University Press
Release : 2013-03-21
ISBN : 0199934894
Language : En, Es, Fr & De

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Book Description :

The Oxford Handbook of Quantitative Methods in Psychology provides an accessible and comprehensive review of the current state-of-the-science and a one-stop source for learning and reviewing current best-practices in a quantitative methods across the social, behavioral, and educational sciences.

The Asymmetrical Brain

The Asymmetrical Brain Book
Author : Kenneth Hugdahl,Richard J. Davidson
Publisher : MIT Press
Release : 2004
ISBN : 9780262582544
Language : En, Es, Fr & De

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Book Description :

Research on brain asymmetry, with particular emphasis on findings made possible by recent advances in neuroimaging.

Oxygen Transport to Tissue XXXI

Oxygen Transport to Tissue XXXI Book
Author : Eiji Takahashi,Duane F. Bruley
Publisher : Springer Science & Business Media
Release : 2010-03-10
ISBN : 9781441912411
Language : En, Es, Fr & De

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Book Description :

The International Society on Oxygen Transport to Tissue (ISOTT, www. isott. info) is an interdisciplinary society comprising about 250 members worldwide. Its purpose is to further the understanding of all aspects of the processes involved in the transport of oxygen from the air to its ultimate consumption in the cells of the various organs of the body. The annual meeting brings together scientists, engineers, clinicians and mathematicians in a unique int- national forum for the exchange of information and knowledge, the updating of participants on latest developments and techniques, and the discussion of controversial issues within the field of oxygen transport to tissue. Founded in 1973, the society has been the leading platform for the presentation of many of the technological and conceptual developments within the field both at the meetings themselves and in the proceedings of the society. These have been published first by Plenum Publishing (1973), then by Kluwer Academic/Plenum Publishers and presently by Springer Publishing, all in the Advances In Expe- mental Medicine and Biology Series. The 36th Annual ISOTT conference was held in Sapporo, Japan during August 3–7, 2008. It was the second occasion that the ISOTT meeting was held in Japan; the first one was held in the same place in 1987 organized by Professor Masaji Mochizuki.

NeuroPET

NeuroPET Book
Author : K. Herholz,P. Herscovitch,W.-D. Heiss
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642187668
Language : En, Es, Fr & De

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Book Description :

- Authors are all experts in the field; Herscovitch is head of PET Imaging at NIH. - PET is becoming dominant technology for diagnosis in Neurology; books have not caught up. NeuroPET is ahead of the curve.

Clinical Applications of Functional MRI An Issue of Neuroimaging Clinics

Clinical Applications of Functional MRI  An Issue of Neuroimaging Clinics  Book
Author : Jay J. Pillai
Publisher : Elsevier Health Sciences
Release : 2014-11-13
ISBN : 0323323847
Language : En, Es, Fr & De

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Book Description :

Editor Jay J. Pillai and authors review important areas in Clinical Applications of Functional MRI. Articles will include: Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging for Presurgical Planning; Visual Mapping Using Blood Oxygen Level Dependent Functional MRI; Applications of BOLD fMRI and DTI in Epilepsy; Pretherapeutic fMRI in Children; BOLD fMRI for Presurgical Planning; Brain Tensor Imaging for Brain Malformations: Does it Help?; Technical Considerations for fMRI Analysis; Special Considerations/Technical Limitations of BOLD fMRI; The Economics of Functional MRI: Clinical and Research; Memory Assessment in the Clinical Context Using fMRI: A Critical Look at the State of the Field; Resting State BOLD fMRI for Pre-surgical Planning, and more!

Foundational Issues in Human Brain Mapping

Foundational Issues in Human Brain Mapping Book
Author : Stephen José Hanson,Martin Bunzl
Publisher : MIT Press
Release : 2010
ISBN : 0262014025
Language : En, Es, Fr & De

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Book Description :

Neuroimagers and philosophers of mind explore critical issues and controversies that have arisen from the use of brain mapping in cognitive neuroscience and cognitive science.

Whiplash Injury

Whiplash Injury Book
Author : Andreas Otte
Publisher : Springer Science & Business Media
Release : 2012-04-13
ISBN : 3642283551
Language : En, Es, Fr & De

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Book Description :

In the past two decades much has been published on whiplash injury, yet both the confusion regarding the condition and the medicolegal discussion surrounding it have increased. In this scenario, a guide to recent and current international research in the field is more necessary than ever. Especially functional imaging methods – such as single-photon emission tomography, positron emission tomography, functional MRI, and hybrid techniques – have demonstrated a variety of significant brain alterations. This book accordingly offers a critical approach to the challenging interpretation of the new research data obtained using functional neuroimaging in whiplash injury. It covers all aspects, including the imaging tools themselves and the different methods of image analysis. Whiplash Injury: New Methods of Functional Neuroimaging will hopefully help patients, their relatives and friends, physicians, and others to understand this condition as a disease.

Brain Mapping

Brain Mapping Book
Author : Arthur W. Toga,John C. Mazziotta
Publisher :
Release : 1996
ISBN : 9780126925401
Language : En, Es, Fr & De

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Book Description :

A methodological volume with a comprehensive view of all approaches used to map the brain. The book discusses assumptions, limitations and advantages of various methods and techniques, and integrates the information collected by using them all.

Imaging in Neurodegenerative Disorders

Imaging in Neurodegenerative Disorders Book
Author : Luca Saba
Publisher : OUP Oxford
Release : 2015-01-08
ISBN : 0191651400
Language : En, Es, Fr & De

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Book Description :

Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Multimodal Brain Image Analysis

Multimodal Brain Image Analysis Book
Author : Pew-Thian Yap,Tianming Liu,Dinggang Shen,Carl-Fredrik Westin,Li Shen
Publisher : Springer
Release : 2012-09-18
ISBN : 3642335306
Language : En, Es, Fr & De

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Book Description :

This book constitutes the refereed proceedings of the Second International Workshop on Multimodal Brain Image Analysis, held in conjunction with MICCAI 2012, in Nice, France, in October 2012. The 19 revised full papers presented were carefully reviewed and selected from numerous submissions. The objective of this workshop is to forward the state of the art in analysis methodologies, algorithms, software systems, validation approaches, benchmark datasets, neuroscience, and clinical applications.

Exploration of Cortical Function

Exploration of Cortical Function Book
Author : M. Stetter
Publisher : Springer Science & Business Media
Release : 2002-01-31
ISBN : 9781402004360
Language : En, Es, Fr & De

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Book Description :

Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing strategies. Topics include optical detection techniques of population activity in the sub-millimeter range, advanced methods for the statistical analysis of these data, and biologically inspired neuronal modeling techniques for population activities in the frameworks of optimal coding, statistical learning theory, and mean-field recurrent networks. Exploration of Cortical Function is unique in that it covers one complete branch of population-based brain research ranging from techniques for data acquisition over data analysis up to modeling techniques for the quantification of functional principles. The volume covers an area which is of great current interest to researchers working on cerebral cortex. The combination of models and image analysis techniques to examine the activity of large cohorts of neurons is especially intriguing and prone to considerable error and debate. The intended readership is students and researchers from many disciplines, including neuroscience, biology, physics, and computer science, interested in how an interdisciplinary framework from biology advanced statistics and computational neuroscience can be used to gather a quantitative understanding of cortical function. Experimentalists may gain insight into statistical and neuronal modeling techniques, whereas theoreticians will find an introductory treatment of neuroanatomy, neurophysiology, and measurement techniques.