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Staphylococcus aureus

Staphylococcus aureus Book
Author : Fabio Bagnoli,Rino Rappuoli,Guido Grandi
Publisher : Springer
Release : 2018-01-24
ISBN : 3319720635
Language : En, Es, Fr & De

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Book Description :

This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens. It includes sixteen chapters that address the microbiology and immunology of S. aureus, the pathology of its key manifestations, and the current standard of care. Further, it reviews cutting-edge advances in alternative therapeutic and prophylactic approaches to antibiotics. All chapters were written by respected experts in the field – presenting recent findings on a diverse range of aspects, they are nonetheless interlinked. As such, the book is a must-read for all researchers, clinicians and technicians engaged in basic or applied science work involving S. aureus.

Staphylococcus aureus

Staphylococcus aureus Book
Author : Alexandra Fetsch
Publisher : Academic Press
Release : 2017-09-06
ISBN : 0128097973
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus provides information on food borne outbreaks of disease and their impact on human health. It is for anyone interested in the features of the pathogen, and its food safety aspects, as well as its prevalence and possible control and eradication options. This is a practical reference for those in the food industry, but also includes some theoretical information useful for advising. The book introduces detailed features and molecular biology of the pathogen, as well as selective methods of detection, prevention and eradication essential for research. It covers methicillin-resistant staphylococcus aureus for food related industries, information on genetic lineages, cell wall components, cell division machinery, molecular characterization, and capillary electrophoresis for detecting and characterizing staphylococcus aureus. Includes information on established and novel antibiotic agents for experimental studies and methods of control and eradication Presents use cases of outbreak studies in molecular and cell biology Provides summary points of detection methods and applicability of those methods to other foodborne pathogens Covers the Staphylococcus aureus’ mode of transmission, detection, biology and impact on foodborne illness

Oral Carriage Suffering of Staphylococcus Aureus

Oral Carriage   Suffering of Staphylococcus Aureus Book
Author : Biswajit Batabyal
Publisher : Educreation Publishing
Release : 2017-06-25
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The oral cavity carriage and antibiotic susceptibility patterns of Staphylococcus aureus in Dental hospital staff and healthy general population were determined. Oral cavity swabs were taken from 113 healthy general population and 90 health care workers. Antibiotic disc susceptibility testing was conducted following the CLSI method. Staphylococcus aureus carriage was noted in 28.3% of healthy general population and 38.9% of health care workers. Resistance to commonly used oral antibiotics of healthy general population & health care workers, ampicillin 93.8% & 97.2%, amoxicillin/clavulanic acid 84.4% & 77.2%, amoxicillin 43.8% & 57.2%, ciprofloxacin 53.2% & 57.2% and ofloxacin 37.5% & 42.9%, respectively. 5.7% methicillin resistant Staphylococcus aureus was detected among the hospital personnel from isolated strain. The MRSA isolates showed multiple drug resistance (MDR), except imipenem. Hospitals should assess the advantages and disadvantages of routinely culturing personnel, however, in outbreak situation hospital personnel especially young persons may be sources of nosocomial infection. Staphylococcus aureus is a well-recognized pathogen associated with a variety of clinical syndrome. The role of Staph. aureus in some types of oral disease may be more important than previously recognized. The present study was designed to investigate the prevalence of Staphylococcus aureus, MRSA and their rate of resistance to different anti staphylococcal antibiotics. For this study, Gurunanak Institute of Dental Science & Research (Kolkata), selected patients who were suffering from Staphylococcus aureus oral infection. Isolated Staphylococcus aureus was tested for Oxacillin (1 mcg) sensitivity and their antibiotic susceptibility was investigated by using eighteen antibiotics followed by Disk diffusion technique following CLSI method. Out of the 223 specimens collected, 109 (48.8%) were isolated. All the 109 (48.8%) specimens were studied in detail. 5.5% of the isolates were shown to be methicillin resistant Staph. aureus (MRSA). Percentage (%) of resistance in commonly used oral antibiotics are ampicillin98.1%, amoxycillin/clavulanic acid 73.3%, amoxycillin 44.9%, ofloxacin 48.6% and ciprofloxacin 41.2%. The MRSA isolates showed multiple drug resistance (MDR), except linezolid and imipenem. In line with more recent surveys, this retrospective study suggests that Staph. aureus may be more frequent isolate from the oral cavity than hitherto suspected. The role of Staph. aureus in several diseases of the oral mucosa merits further investigation. The problem of infection has been persistent in the surgical world even after the introduction of antibiotics. Pathogens that infect surgical site can be acquired from the hospital environment or other infected patients. A total of 66 pus samples from post-operative oral & maxillofacial surgical infections were received in the Department of Microbiology, Gurunanak Institute of Dental Science & Research, Panihati, Kolkata, over a period of one year. The isolates were identified using standard laboratory procedures. All the isolates were tested for susceptibility to various commonly used antibiotics and screened for oxacillin susceptibility according to CLSI guidelines. Out of 66 pus samples received, 34(51.5%) were culture positive for Staph. aureus. Methicillin resistance was documented in 14 (41.2%) of the Staph. aureus isolates. Highest efficacy was observed with linezolid (97.0%). All MRSA isolates were 100% sensitive to linezolid. The hospital acquired surgical site infection is alarming. Hospital disinfection and treatment protocols should be practiced.

Staphylococcus aureus

Staphylococcus aureus Book
Author : Fabio Bagnoli,Rino Rappuoli,Guido Grandi
Publisher : Springer
Release : 2018-02-01
ISBN : 9783319720616
Language : En, Es, Fr & De

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Book Description :

This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens. It includes sixteen chapters that address the microbiology and immunology of S. aureus, the pathology of its key manifestations, and the current standard of care. Further, it reviews cutting-edge advances in alternative therapeutic and prophylactic approaches to antibiotics. All chapters were written by respected experts in the field – presenting recent findings on a diverse range of aspects, they are nonetheless interlinked. As such, the book is a must-read for all researchers, clinicians and technicians engaged in basic or applied science work involving S. aureus.

Staphylococcus aureus Infection and Disease

Staphylococcus aureus Infection and Disease Book
Author : Allen Honeyman,Herman Friedman,Mauro Bendinelli
Publisher : Springer Science & Business Media
Release : 2006-04-11
ISBN : 0306468484
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but can be rapidly invasive, spreading through the tissues, invading bone, and seeding the bloodstream to produce a fulminant picture of septic shock, disseminated intravascular coagulation, and rapid death. Moreover, most strains of staph infections are becoming resistant to most antibiotics, thus posing a significant problem for hospitals and health care facilities. This book, a volume in the Infectious Agents and Pathogenesis series, presents chapters by the major researchers in the field.

Staphylococcus Aureus Infections

Staphylococcus Aureus Infections Book
Author : Lisa Freeman-Cook,Kevin D. Freeman-Cook,I. Edward Alcamo,David L. Heymann
Publisher : Infobase Publishing
Release : 2006
ISBN : 1438101686
Language : En, Es, Fr & De

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Book Description :

Discusses staphylococcus aureus bacteria and the infections they can cause, their diagnosis, treatment, and more.

Staphylococcus aureus Toxins

Staphylococcus aureus Toxins Book
Author : William R. Schwan
Publisher : MDPI
Release : 2019-08-20
ISBN : 303921425X
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus is a common inhabitant of the human body with which we co-exist. However, this species can also cause disease in humans when an appropriate opportunity arises, such as a cut or some other breakdown in our body’s defenses. S. aureus is able to initiate infections due, in part, to the diverse group of toxins that they secrete. The exotoxins produced by S. aureus can cause direct damage, thwart our own body’s defenses, or trigger massive amounts of cytokines that lead to indirect damage within the human body. In this book are 12 research articles that deal with different aspects of staphylococcal exotoxins. Some of the work gives an overview about how the toxins contribute to the disease process. Other articles discuss different aspects of several exotoxins, and two articles are centered on countermeasures against S. aureus infections. Overall, this book will give the reader a good overview of how staphylococcal exotoxins contribute to initiating and sustaining infections in humans.

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus Book
Author : Shymaa Enany,Laura Crotty Alexander
Publisher : BoD – Books on Demand
Release : 2017-03-08
ISBN : 953512983X
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus S. aureus is a growing issue both within hospitals and community because of its virulence determinants and the continuing emergence of new strains resistant to antimicrobiotics. In this book, we present the state of the art of S. aureus virulence mechanisms and antibiotic-resistance profiles, providing an unprecedented and comprehensive collection of up-to-date research about the evolution, dissemination, and mechanisms of different staphylococcal antimicrobial resistance patterns alongside bacterial virulence determinants and their impact in the medical field. We include several review chapters to allow readers to better understand the mechanisms of methicillin resistance, glycopeptide resistance, and horizontal gene transfer and the effects of alterations in S. aureus membranes and cell walls on drug resistance. In addition, we include chapters dedicated to unveiling S. aureus pathogenicity with the most current research available on S. aureus exfoliative toxins, enterotoxins, surface proteins, biofilm, and defensive responses of S. aureus to antibiotic treatment.

Staphylococcus Aureus

Staphylococcus Aureus Book
Author : D A Aldeen,K Hiramatsu
Publisher : Elsevier
Release : 2004-05-01
ISBN : 0857099906
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus is resident in skin and nasal membranes with a formidable pathogenic potential to cause a variety of community and hospital acquired infections. This authoritative survey covers the impact of genome sequences into our understanding of MRSA and MSSA pathogenesis. World specialists from America, Germany, Japan, Sweden and the UK contribute knowledge and experience which will be welcome to researchers, practitioners and postgraduate students of immunology, microbiology, bacteriology and pharmacology worldwide. An authoritative survey that covers the impact of genome sequences into the understanding of MRSA and MSSA pathogenesis World specialists from America, Germany, Japan, Sweden and the UK contribute knowledge and experience

Frontiers in Staphylococcus aureus

Frontiers in Staphylococcus aureus Book
Author : Shymaa Enany,Laura Crotty Alexander
Publisher : BoD – Books on Demand
Release : 2017-03-08
ISBN : 9535129813
Language : En, Es, Fr & De

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Book Description :

Staphylococcus was first recognized as a human pathogen in 1880 and was named for its grape cluster-like appearance. In 1884, Staphylococcus aureus was identified and named for its vibrant golden color, which was later found to be the result of golden toxin production. Here, experts examine in-depth patterns of S. aureus colonization and exposures in humans, mammals, and birds that have led to the development of various clinical diseases. The mode of transmission of S. aureus and different methods for its detection in different samples are defined. Conventional antibiotic options to treat this aggressive, multifaceted, and readily adaptable pathogen are becoming limited. Alternative, novel chemotherapeutics to target S. aureus are discussed in the pages within, including herbal medicines, bee products, and modes of delivery.

Methicillin Resistant Staphylococcus Aureus MRSA Protocols

Methicillin Resistant Staphylococcus Aureus  MRSA  Protocols Book
Author : Yinduo Ji
Publisher : Humana Press
Release : 2016-08-23
ISBN : 9781493960569
Language : En, Es, Fr & De

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Book Description :

Presenting the most up-to-date techniques for the detection, genotyping, and investigation of methicillin-resistant S. aureus (MRSA), this second edition of Methicillin-Resistant Staphylococcus aureus (MRSA) Protocols collects chapters that utilize the power of complete genomic sequences and advanced high-throughput technologies that have pushed this field to its present state. These enable the development of specific and rapid diagnosis methods, the investigation and elucidation of mechanisms of bacterial evolution to antibiotic resistance and pathogenicity, and the identification of novel targets to develop more potent therapeutic and/or preventive agents. Written for the Methods in Molecular Biology series, numerous chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, Methicillin-Resistant Staphylococcus aureus (MRSA) Protocols, Second Edition serves as a key reference for researchers attempting to set up a new method to study MRSA or even for technicians and scientists working on other pathogens.

Staphylococcus Aureus

Staphylococcus Aureus Book
Author : Hassan Hemeg,Hani Ozbak,Farhat Afrin
Publisher : Unknown
Release : 2019
ISBN : 1789845920
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus strains are an important medical infectious agent that causes a wide range of pathogeneses starting from colonization of the skin and mucosal surface to severe pathogenic effects such as septicemia. The mortality and morbidity from this pathogen are challenging issues for the healthcare premises. Methicillin Resistant Staphylococcus aureus strains (MRSA) are causing severe infections due to the genes that are resistant to several antibiotics including methicillin, aminoglycosides, and others. Recently, there have been several reports related to failure of treatment plans caused by MRSA that led to Vancomycin Intermediate Staphylococcus aureus strains (VISA) or, in sporadic cases, resistance to the drug of choice. This book highlights the new areas for the treatment of MRSA using natural products. The implementation of specific products produced by this organism can help the scientist to obtain a new window for treatments such as anticancer chemotherapy, antioxidants, etc.

Staphylococcus Aureus

Staphylococcus Aureus Book
Author : Maluda
Publisher : Unknown
Release : 2017
ISBN : 9781634859738
Language : En, Es, Fr & De

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Book Description :

Author Biography: Maria de Lourdes Ribeiro de Souza da Cunha, MD in Science and Technology of the Food (1992), PhD in Tropical Diseases (1998); is biologist with main research interests in Microbiology, focusing on Bacteriology, acting on the following subjects: Staphylococcus aureus, Coagulase-Negative Staphylococci (CoNS), epidemiology, virulence factors, biofilms, enterotoxins and antimicrobial resistance. She is professor and researcher at the Department of Microbiology and Immunology of the Bioscience Institute, S�o Paulo State University (UNESP), Botucatu, SP, Brazil; Scholarship in Research Productivity of the National Council for Scientific and Technological Development (CNPq), an agency linked to the Ministry of Science and Tecnology (MCT), dedicated to the promotion of scientific and technological research and to the formation of human resources for research in the Brazil. Professor and mentor master''s, doctoral and postdoctoral studies at the graduate program in Tropical Diseases, Faculty of Medicine of Botucatu and the Post-graduation in General Biology and Applied, Biosciences Institute, UNESP, Botucatu, SP, Brazil. She is involved in research projects as a scientific reference in Staphylococcus supported for the S�o Paulo Research Foundation - FAPESP - public foundation with the mission to foster research and the scientific and technological development of the State of S�o Paulo, Brazil. She is the author of more than 80 papers in international peer reviewed journals and books, and referee for about 20 journals. Book Description: This book provides an overview of the different topics of staphylococcal research in recent years. Severe infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become a global health problem in the twenty-first century. Chapter One discusses MRSA as a major cause of healthcare or hospital-associated infections (HA-MRSA) in burn patients, indicated as a high-risk group for invasive staphylococcal infection. Types of MRSA, which have traditionally been tackled as exclusive agents of healthcare-associated infections, are now recognized as the causative agents of severe disease acquired in the community. The second chapter discusses these infections as they occur mainly in "special populations". For example, we may cite people living with HIV/AIDS, older adults living in long-term care facilities and patients with chronic diseases, notably diabetes mellitus. In Chapter Three, a third epidemiological form of MRSA is discussed, which is known as livestock-associated MRSA (LA-MRSA). Chapter Four emphasizes the current scenario of highly adaptable clonal complexes. Among these strains, LA-MRSA belonging to clonal complex (CC) 398 are particularly important, and nosocomial infections caused by strains of CC398 are frequently reported. Confirmation of the presence of microorganisms in blood cultures is one of the most important roles of clinical microbiology laboratories. Blood culture testing - the gold standard for the diagnosis of sepsis - is able to elucidate the etiology of infection and to establish appropriate antibiotic treatment in order to improve the prognosis of septic patients and, consequently, to reduce morbidity and mortality; this is the subject discussed in Chapter Five. Nosocomial infections manifest more intensely and more frequently in newborns when compared to children or adults. Staphylococcus aureus infections in newborns is discussed in Chapter Six. Staphylococcus spp. are an important cause of peritonitis in peritoneal dialysis (PD), frequently requiring change of the dialysis technique and causing an important impact on the mortality of PD patients, another matter of great importance which is discussed in Chapter Seven. Finally, the epidemiology and experimental evidence that S. aureus and its products, the superantigens, are directly related to the development or exacerbation of autoimmune diseases, which are discussed in Chapter Eight. This book provides an excellent overview of the different applications of staphylococcal research for clinicians, researchers and students who intend to address these issues, and permits continued high-quality research involving these important pathogens. Target Audience: The book provides an excellent overview in the different applicative fields staphylococcal research for clinicians, researchers and students.

An Evaluation of Staphylococcus Aureus Knowledge and Information Processing for Herd and Cow Level Decision making

An Evaluation of Staphylococcus Aureus Knowledge and Information Processing for Herd and Cow Level Decision making Book
Author : Sandra Swindell Costello
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download An Evaluation of Staphylococcus Aureus Knowledge and Information Processing for Herd and Cow Level Decision making book written by Sandra Swindell Costello, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Staphylococcus aureus

Staphylococcus aureus Book
Author : Kelly C. Rice
Publisher : Humana
Release : 2021-07-08
ISBN : 9781071615492
Language : En, Es, Fr & De

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Book Description :

This volume details the phenotypic characterization of Staphylococcus aureus, with a focus on in vitro and ex vivo methodologies. The chapters in this book cover topics such as in vitro assessment of classical S. aureus virulence attributes; quantifying promoter activity using a S. aureus codon-optimized lacZ plasmid; biologically-relevant growth environments; metabolic and stress resistance assays; and in vivo and ex vivo models of host-pathogen interaction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Staphylococcus aureus: Methods and Protocols is a valuable resource for anyone interested in this fascinating and developing field.

Exploring the Molecular Basis of Host Specialisation in Staphylococcus Aureus

Exploring the Molecular Basis of Host Specialisation in Staphylococcus Aureus Book
Author : Tingli Yang
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Staphylococcus aureus, more commonly known as the 'superbug' MRSA (multi-resistant S. aureus), colonises a wide variety of mammals and is one of the most common causes of hospital and community infections. Progress in the field has been hampered by the lack of mouse models which closely mimic the clinical situation. A unique mouse-adapted S. aureus strain JSNZ was recently isolated from C57BL/6J mice with preputial gland infections in the animal facility at University of Auckland. JSNZ has been demonstrated to be a good experimental tool for understanding host - S. aureus interactions using mice. JSNZ carries a unique gene (jep) encoding a putative serine protease (JEP), which is missing from all other sequenced strains of S. aureus. The overall aim of this study is to explore the role of JEP in the virulence of S. aureus. To achieve this aim, we constructed a JEP mutant in the mouse-adapted strain JSNZ, by knocking out jep. Then in order to explore whether JEP has a function in the resistance of JSNZ to clearance by the innate immune system, we compared the survival ability of wild-type and mutant JSNZ in mouse and human whole blood killing assays, in comparison to a human-adapted S. aureus strain Newman. While no significant difference was found between wild-type and mutant JSNZ both in mouse blood or human blood, we found that mouse-adapted strains can grow after 3 h incubation in mouse blood but not in human blood. In contrast, Newman did not grow in mouse or human blood. We also compared the in vivo virulence of wild-type and mutant JSNZ in the Galleria mellonella larvae virulence assay; however no difference was found between these two strains. While the role of JEP in the virulence of S. aureus JSNZ remains unclear, the jep knockout JSNZ strain constructed during this work should prove useful in future studies.

Occurrence and Health Significance of Staphylococcus Aureus in a Pig Slaughter Line

Occurrence and Health Significance of Staphylococcus Aureus in a Pig Slaughter Line Book
Author : Urszula Janina Narucka
Publisher : Taylor & Francis
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Occurrence and Health Significance of Staphylococcus Aureus in a Pig Slaughter Line book written by Urszula Janina Narucka, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Growth of Staphylococcus Aureus in a Null Magnetic Field Environment

Growth of Staphylococcus Aureus in a Null Magnetic Field Environment Book
Author : Dietrich E. Beischer,Glenda S. Cowart
Publisher : Unknown
Release : 1970
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

No significant differences were observed between the growth of S. aureaus in the geomagnetic field and in a magnetic field with a field strength reduced by a factor of 1000. Pigmentation, mannitol fermentation, gelatinase activity, coagulase production, and catalase activity were also not influenced by the low magnetic field. (Author).

Staphylococcus aureus contamination levels in selected local herbal medicines sold in Kampala Uganda

 Staphylococcus aureus  contamination levels in selected local herbal medicines sold in Kampala  Uganda Book
Author : Derick Niyonshima
Publisher : GRIN Verlag
Release : 2018-06-06
ISBN : 3668719144
Language : En, Es, Fr & De

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Book Description :

Bachelor Thesis from the year 2016 in the subject Medicine - Public Health, grade: 75.0, Makerere University, course: Biomedical Laboratory Technology, language: English, abstract: Herbal medicine use in Uganda and the world at large is at its peak because of the documented efficacy, effectiveness, cheap cost and less side effects. The estimates of herbal medicine users in the world is 80% and 60% in Uganda, yet with all this demand, less effort has been put to ensure that they are free from bacterial contamination. The study therefore aimed at determining Staphylococcus aureus contamination of selected liquid herbal medicines sold in Kampala, Uganda with the following specific objectives; to provide an update on the different local herbal medicines sold in Kampala, Uganda and the conditions they treat; to determine Staphylococcus aureus contamination levels of selected liquid local herbal medicines sold in Kampala, Uganda; and to establish the antibacterial susceptibility patterns of isolated Staphylococcus aureus. A questionnaire was used to collect data on the different local herbal medicines sold in Kampala, Uganda. To determine levels of Staphylococcus aureus contamination, microbial culture was performed on 30 selected liquid herbal medicine samples. In addition Staphylococcus aureus susceptibility patterns were determined by subjecting isolated Staphylococcus aureus species to gentamicin 10μg, chloramphenicol 30 30μg ampicillin 10μg, penicillin 10U and tetracycline 30μg. A total of one hundred and seventy local herbal medicines were identified and classified into twenty five categories basing on conditions they treat. I therefore recommend that herbal medicines should be tested for bacterial quality by regulatory bodies before being sold to patients to avoid Staphylococcus aureus infection hence avoiding treatment costs. In addition, herbal medicine practitioners should embark on good manufacturing practices to avoid contamination of herbal medicines.

Effects of Coliform Bacteria on Growth of Staphylococcus Aureus

Effects of Coliform Bacteria on Growth of Staphylococcus Aureus Book
Author : Joseph Vincent Di Giacinto
Publisher : Unknown
Release : 1964
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Effects of Coliform Bacteria on Growth of Staphylococcus Aureus book written by Joseph Vincent Di Giacinto, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.