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Spontaneous Pathology Of The Laboratory Non Human Primate

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Spontaneous Pathology of the Laboratory Non human Primate

Spontaneous Pathology of the Laboratory Non human Primate Book
Author : Alys E Bradley,Jennifer Chilton
Publisher : Academic Press
Release : 2019-06-15
ISBN : 9780128130889
Language : En, Es, Fr & De

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Book Description :

Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. By providing that background information, this text solves that problem. This book serves as a "go to" text for all pathologists working on primates in safety assessment studies, and to help diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these species in zoological collections. Primate species included are rhesus and cynomolgus macaques, and marmosets. Multi-authored chapters are arranged by organ system. Comprehensive text that describes the spontaneous pathology seen in the common laboratory primate species: rhesus and cynomolgus macaques, and marmosets Color illustrations depict the most common lesions to augment the descriptions Descriptions are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP), and currently utilized in rodent manuscripts published in the Japanese Journal of Toxicological Pathology and the Journal of Toxicologic Pathology Provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines

The Baboon in Biomedical Research

The Baboon in Biomedical Research Book
Author : John L. VandeBerg,Sarah Williams-Blangero,Suzette D. Tardif
Publisher : Springer Science & Business Media
Release : 2009-06-04
ISBN : 9780387759913
Language : En, Es, Fr & De

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Book Description :

Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.

CRC Handbook of Laboratory Animal Science

CRC Handbook of Laboratory Animal Science Book
Author : Edward C. Melby,Norman H. Altman
Publisher : Unknown
Release : 1974
ISBN : 9780878193448
Language : En, Es, Fr & De

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Book Description :

Download CRC Handbook of Laboratory Animal Science book written by Edward C. Melby,Norman H. Altman, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pathology of Laboratory Animals

Pathology of Laboratory Animals Book
Author : Kurt Benirschke,F.M. Garner,T.C. Jones
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 146129942X
Language : En, Es, Fr & De

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Book Description :

Laboratory Animal Medicine has made enor We deeply appreciate the efforts of each of the mous strides in the 47 years since R. Jaffe published authors and co-authors of the 23 chapters in this his "Anatomy and Pathology of Spontaneous Dis two volume work. In some instances the reader will eases of Small Laboratory Animals" in 1931. So note what appears to be repetition in certain chap ters. This repetition was allowed to stand in some much new information had accumulated that in a cases because different approaches seemed useful, new edition in 1958, Jaffe, aided by Cohrs and Meessen, needed the assistance of 46 colleagues to although efforts were made to delete most of the do the subject justice. Like its predecessor, this two redundancy which inevitably arises in a venture of volume comprehensive treatise on "Pathologie der this kind. We will be grateful if our colleagues point out errors and send us specific and general Laboratoriumstiere" was written in German and criticism of this work to allow corrections in the thus not readily available to the widening circle of event of reprinting or a next edition. veterinarians and pathologists who now are inter One objective has been to assemble current in ested in laboratory animals. Aside from the need to have a comprehensive formation in the pathologic aspects of diseases of review of laboratory animal pathology in English, laboratory animals.

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : Anonim
Publisher : Elsevier
Release : 1998-07-24
ISBN : 9780080537634
Language : En, Es, Fr & De

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Book Description :

This volume and its companion Nonhuman Primates in Biomedical Research: Biology and Management represent the most comprehensive publications of their type on nonhuman primates. This volume addresses the diseases of nonhuman primates with an emphasis on the etiological factors, clinical signs, diagnostic pathology, therapy, and management. Its companion volume serves as a general reference for those who provide care for these animals and for those who use them in biomedical research.

Nonhuman Primates

Nonhuman Primates Book
Author : Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642849245
Language : En, Es, Fr & De

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Book Description :

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The M on ographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stud ies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book on nonhuman primate pathology is the 12th volume of a set of monographs prepared under the sponsorship of the International Life Sciences Institute (ILSI).

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publisher : Academic Press
Release : 2012-04-12
ISBN : 0123813662
Language : En, Es, Fr & De

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Book Description :

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment Book
Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
Publisher : Academic Press
Release : 2015-03-13
ISBN : 012417146X
Language : En, Es, Fr & De

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Book Description :

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

Background Lesions in Laboratory Animals E Book

Background Lesions in Laboratory Animals E Book Book
Author : Elizabeth Fiona McInnes
Publisher : Elsevier Health Sciences
Release : 2011-10-24
ISBN : 0702049247
Language : En, Es, Fr & De

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Book Description :

Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

Nonhuman Primates I

Nonhuman Primates I Book
Author : Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642849067
Language : En, Es, Fr & De

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Book Description :

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The Mo nographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stu dies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors -strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on Nonhuman Primates, is the eleventh volume of a set pre pared under the sponsorship of the International Life Sciences Institute (ILSI).

Laboratory Animal Science

Laboratory Animal Science Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Laboratory Animal Science book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Spontaneous and External Radiation Related Tumors in Nonhuman Primates A Survey

Spontaneous and External Radiation Related Tumors in Nonhuman Primates  A Survey Book
Author : Anonim
Publisher : Unknown
Release : 1972
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A survey was made of the occurrence of spontaneous and external radiation-related tumors in primates. More than 30 tumors related to irradiation exposure and more than 270 spontaneous tumors were found. The 137 literature references concerning these tumors are listed, in two comprehensive tables, according to the location and type of tumor, as well as to the species, sex, and age of the respective primates. (Author).

Laboratory Primate Newsletter

Laboratory Primate Newsletter Book
Author : Anonim
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Laboratory Primate Newsletter book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nonhuman Primate Models For Human Diseases

Nonhuman Primate Models For Human Diseases Book
Author : W. Richard Dukelow
Publisher : CRC Press
Release : 2018-02-06
ISBN : 135109193X
Language : En, Es, Fr & De

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Book Description :

While research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of human medical research that are under intensive research study today. Authors were then selected based on their expertise at using nonhuman primates as models for the human condition. Each was asked to use as comparative an approach as models for the human condition. Each was asked to use a comparative an approach as possible, to provide the reader with knowledge relating to the usefulness of various nonhuman primate species to each specific research area.

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : B. Taylor Bennett,Christian R. Abee,Roy Henrickson
Publisher : Unknown
Release : 1998
ISBN : 0120886650
Language : En, Es, Fr & De

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Book Description :

This volume addresses the diseases of nonhuman primates with an emphasis on the etiological factors, clinical signs, diagnostic pathology, therapy, and management.

Gann the Japanese journal of cancer research

Gann   the Japanese journal of cancer research Book
Author : Anonim
Publisher : Unknown
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Gann the Japanese journal of cancer research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Primate Report

Primate Report Book
Author : Anonim
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Primate Report book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pathology for Toxicologists

Pathology for Toxicologists Book
Author : Elizabeth McInnes
Publisher : John Wiley & Sons
Release : 2017-03-16
ISBN : 1118755316
Language : En, Es, Fr & De

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Book Description :

Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary

AIDS Research and Human Retroviruses

AIDS Research and Human Retroviruses Book
Author : Anonim
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download AIDS Research and Human Retroviruses book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Non human Primate Models for Study of Human Reproduction

Non human Primate Models for Study of Human Reproduction Book
Author : T. C. Anand Kumar
Publisher : S Karger Ag
Release : 1980
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Non human Primate Models for Study of Human Reproduction book written by T. C. Anand Kumar, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.