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Spine Phenotypes

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Spine Phenotypes

Spine Phenotypes Book
Author : Dino Samartzis,Jaro I. Karppinen,Frances M.K. Williams
Publisher : Academic Press
Release : 2022-07-08
ISBN : 0128227796
Language : En, Es, Fr & De

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Book Description :

The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry. Book chapters devoted to specific imaging phenotypes with discussion of their clinical correlates Imaging phenotypes provided with examples of established phenotypic measurements and a range of normal and pathologic images Multiauthor, multidisciplinary contributions comprising world leaders in the field of spine imaging, research, and clinical practice

Atlas of Spinal Imaging Phenotypes

Atlas of Spinal Imaging Phenotypes Book
Author : Philip Louie,Howard S. An,Dino Samartzis
Publisher : Elsevier Health Sciences
Release : 2021-03-23
ISBN : 0323761127
Language : En, Es, Fr & De

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Book Description :

Spine-related pain is the world’s leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging Phenotypes: Classifications and Radiographic Measurements is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. Helps readers better understanding spinal phenotypes and their imaging, and how today’s knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. Includes validated classification systems that complement the phenotypes and radiographic measurements. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.

Abnormal Skeletal Phenotypes

Abnormal Skeletal Phenotypes Book
Author : Alessandro Castriota-Scanderbeg,Bruno Dallapiccola
Publisher : Springer Science & Business Media
Release : 2006-03-20
ISBN : 3540303618
Language : En, Es, Fr & De

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Book Description :

Taking a symptom-oriented approach, this book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. Its clear structure makes it an essential, practical guide for radiologists, geneticists, and pediatricians.

Dendritic spines from shape to function

Dendritic spines  from shape to function Book
Author : Nicolas Heck,Ruth Benavides-Piccione
Publisher : Frontiers Media SA
Release : 2016-02-03
ISBN : 2889197662
Language : En, Es, Fr & De

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Book Description :

One fundamental requisite for a comprehensive view on brain function and cognition is the understanding of the neuronal network activity of the brain. Neurons are organized into complex networks, interconnected through synapses. The main sites for excitatory synapses in the brain are thin protrusions called dendritic spines that emerge from dendrites. Dendritic spines have a distinct morphology with a specific molecular organization. They are considered as subcellular compartments that constrain diffusion and influence signal processing by the neuron and, hence, spines are functional integrative units for which morphology and function are tightly coupled. The density of spines along the dendrite reflects the levels of connectivity within the neuronal network. Furthermore, the relevance of studying dendritic spines is emphasized by the observation that their morphology changes with synaptic plasticity and is altered in many psychiatric disorders. The present Research Topic deals with some of the most recent findings concerning dendritic spine structure and function, showing that, in order to understand how brain neuronal activity operates, these two factors should be regarded as being intrinsically linked.

Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancers and Diseases

Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancers and Diseases Book
Author : Liang Cheng,Lei Deng,Chuan-Xing Li,Mingxiang Teng,Yan Zhang
Publisher : Frontiers Media SA
Release : 2022-02-16
ISBN : 2889718069
Language : En, Es, Fr & De

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Book Description :

Download Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancers and Diseases book written by Liang Cheng,Lei Deng,Chuan-Xing Li,Mingxiang Teng,Yan Zhang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Growing Spine

The Growing Spine Book
Author : Behrooz A. Akbarnia,Muharrem Yazici,George H. Thompson
Publisher : Springer
Release : 2015-11-02
ISBN : 3662482843
Language : En, Es, Fr & De

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Book Description :

The second edition of The Growing Spine has been extensively revised to cover recent advances in knowledge and management. The book is intended as a comprehensive, one-stop reference for specialists and health professionals who care for young children with spinal deformities. In addition, it will effectively help to standardize the care of these patients. Depending on the etiology, children with spinal deformities are often cared for by multiple specialists, including pediatricians, pediatric orthopaedists or orthopaedic spine surgeons, neurologists, pediatric surgeons, pediatric neurosurgeons, oncologists, and pulmonologists. The multidisciplinary nature of care is reflected in The Growing Spine, which will be of value for all involved practitioners rather than just orthopaedic specialists. It will also be an ideal reference for nurses, physical therapists, and healthcare professionals in training, who are usually unfamiliar with spinal deformities in children.

Diagnostic Imaging Spine E Book

Diagnostic Imaging  Spine E Book Book
Author : Jeffrey S. Ross,Kevin R. Moore
Publisher : Elsevier Health Sciences
Release : 2015-08-21
ISBN : 0323400604
Language : En, Es, Fr & De

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Book Description :

With constant improvements to MR image quality, it's important to have a resource reflecting the most recent developments. Diagnostic Imaging: Spine, now in its third edition, showcases the latest cutting-edge research from Dr. Jeffrey Ross and his team of experts in the field. Expanding upon the core of the highly popular second edition, this updated reference is fully revised to provide the best spine-related diagnostic support available. Covers the latest advancements in imaging the postoperative spine, including bone morphogenetic protein (BMP) utilization Includes additional genetic information, such as OMIM entry numbers, where appropriate Highlights updates to new classification and grading schemes Hundreds of full-color pathology images are carefully annotated to help pinpoint the most relevant factors New references direct you to additional trustworthy resources Bulleted lists provide guidance through the intricacies of the spine Presents brand new images and cases to keep you at the forefront of your field Medicine eBook is accessible on a variety of devices

Diagnostic Imaging Spine E Book

Diagnostic Imaging  Spine   E Book Book
Author : Jeffrey S. Ross,Kevin R. Moore
Publisher : Elsevier Health Sciences
Release : 2020-11-16
ISBN : 0323794009
Language : En, Es, Fr & De

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Book Description :

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Spine, fourth edition, is an invaluable resource for general radiologists, neuroradiologists, and trainees—anyone who requires an easily accessible, highly visual reference on today’s spinal imaging. Drs. Jeffrey Ross, Kevin Moore, and their team of highly regarded experts provide updated information on disease identification and imaging techniques to help you make informed decisions at the point of care. The text is lavishly illustrated, delineated, and referenced, making it a useful learning tool as well as a handy reference for daily practice. Serves as a one-stop resource for key concepts and information on radiologic imaging and interpretation of spine, spinal cord, and bony vertebral conditions Features more than 2,600 full-color illustrations, including radiologic, pathologic, and clinical images Contains new chapters on recent surgery protocols such as spine instability neoplastic scoring (SINS) and epidural spinal cord compression scale (ESSC) Features updates from cover to cover including revisions in accordance with new information on inflammatory and autoimmune disorders and systemic manifestations of diseases Provides expanded imaging details for metastatic diseases to accommodate recent significant changes, including new categories of oncologic surgery driven by the use of proton beam radiotherapy, PET MR as a diagnostic modality, and new FDA-approved hardware Includes new information on areas of demyelinating diseases related to better understanding of MS, neuromyelitis optica spectrum disorder, and anti-MOG disorders; a variety of spinal CSF leak pathologies that cause intracranial hypotension; genetic and disease information on schwannomatosis; and much more Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care

Phenotypic Plasticity Evolution

Phenotypic Plasticity   Evolution Book
Author : David W. Pfennig
Publisher : CRC Press
Release : 2021-06-04
ISBN : 1000387585
Language : En, Es, Fr & De

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Book Description :

Phenotypic plasticity – the ability of an individual organism to alter its features in direct response to a change in its environment – is ubiquitous. Understanding how and why this phenomenon exists is crucial because it unites all levels of biological inquiry. This book brings together researchers who approach plasticity from diverse perspectives to explore new ideas and recent findings about the causes and consequences of plasticity. Contributors also discuss such controversial topics as how plasticity shapes ecological and evolutionary processes; whether specific plastic responses can be passed to offspring; and whether plasticity has left an important imprint on the history of life. Importantly, each chapter highlights key questions for future research. Drawing on numerous studies of plasticity in natural populations of plants and animals, this book aims to foster greater appreciation for this important, but frequently misunderstood phenomenon. Key Features Written in an accessible style with numerous illustrations, including many in color Reviews the history of the study of plasticity, including Darwin’s views Most chapters conclude with recommendations for future research

Atlas of Spinal Imaging

Atlas of Spinal Imaging Book
Author : Philip K. Louie, MD,Howard S. An, MD,Dino Samartzis
Publisher : Unknown
Release : 2021-02
ISBN : 9780323761116
Language : En, Es, Fr & De

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Book Description :

Spine-related pain is the world's leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging Phenotypes: Classifications and Radiographic Measurements is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. Helps readers better understanding spinal phenotypes and their imaging, and how today's knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. Includes validated classification systems that complement the phenotypes and radiographic measurements. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.

Canadian Journal of Zoology

Canadian Journal of Zoology Book
Author : Anonim
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Canadian Journal of Zoology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Behavioural Phenotypes in Clinical Practice

Behavioural Phenotypes in Clinical Practice Book
Author : Gregory O'Brien
Publisher : Cambridge University Press
Release : 2002-01-21
ISBN : 9781898683278
Language : En, Es, Fr & De

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Book Description :

Clinics in Developmental Medicine No. 157 Clinicians, educators and other specialists who work with young people with intellectual disabilities are increasingly aware of the extent to which their clients' behaviours are shaped by the respective causal syndrome. This book is a practical response to the need for interventions and ongoing care programmes to take account of this within the context of coordinated multimodal case planning. An international team of experts drawn from child health, special education, psychology, psychiatry and related disciplines explores general principles of case management, in addition to giving consideration to a large number of individual syndromes, resulting in a comprehensive review of the subject. All of the authors have been involved in original research on the themes explored, and in the development of coherent service responses to the challenges posed by behavioural phenotypes. This will be essential reading for all professionals engaged in the care and management of people with intellectual disabilities.

Issues in Biological and Life Sciences Research 2013 Edition

Issues in Biological and Life Sciences Research  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-05-01
ISBN : 1490108688
Language : En, Es, Fr & De

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Book Description :

Issues in Biological and Life Sciences Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Issues in Biological and Life Sciences Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Modulating Glial Cells Phenotype New Findings and Therapies

Modulating Glial Cells Phenotype  New Findings and Therapies Book
Author : Alberto Javier Ramos,Yolanda Diz-Chaves,Maria Jose Bellini
Publisher : Frontiers Media SA
Release : 2020-12-21
ISBN : 2889661830
Language : En, Es, Fr & De

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Book Description :

Download Modulating Glial Cells Phenotype New Findings and Therapies book written by Alberto Javier Ramos,Yolanda Diz-Chaves,Maria Jose Bellini, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neural Stem Cells for Brain and Spinal Cord Repair

Neural Stem Cells for Brain and Spinal Cord Repair Book
Author : Tanja Zigova
Publisher : Springer Science & Business Media
Release : 2002-11-05
ISBN : 1592592988
Language : En, Es, Fr & De

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Book Description :

Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.

Some Effects of the White Spine Uniform Color and Gynoecious Alleles on Quality and Certain Other Characters in the Cucumber Variety Wisconsin SMR 18

Some Effects of the White Spine  Uniform Color and Gynoecious Alleles on Quality and Certain Other Characters in the Cucumber Variety Wisconsin SMR 18 Book
Author : Benjamin Franklin George
Publisher : Unknown
Release : 1971
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Some Effects of the White Spine Uniform Color and Gynoecious Alleles on Quality and Certain Other Characters in the Cucumber Variety Wisconsin SMR 18 book written by Benjamin Franklin George, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Epidemiology of Brain and Spinal Tumors

Epidemiology of Brain and Spinal Tumors Book
Author : Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Publisher : Academic Press
Release : 2021-04-16
ISBN : 0128217553
Language : En, Es, Fr & De

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Book Description :

Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Phenotypic Variation

Phenotypic Variation Book
Author : Moyra Smith M.D., Ph.D., MFA
Publisher : Oxford University Press
Release : 2011-01-10
ISBN : 0199702047
Language : En, Es, Fr & De

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Book Description :

During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles, physiological systems and phenotype. The goal of this book is to present steps in the pathways of exploration to connect genotype to phenotype and to consider how alterations in genomes impact disease. In this book the author reviews published research in functional genomics carried out primarily since 2006 that sheds light on aspects of phenotypic variation. The goal of functional genomics is to gain insight into mechanisms through which specific changes in genome transcripts and regulation induce changes in proteins, pathways, organelles, cellular and tissue functions, morphology and ultimately in phenotype. Topics reviewed include investigations in genome architecture, gene structure, gene regulation epigenetic modifications and function of organelles including mitochondria, and the endosome lysosome system. New insights into neurodevelopment and neurobehavioral disorders gained through functional genomic research are presented. Aspects of genomic studies in complex common diseases are reviewed. Molecular genetic variations and aberrations in cellular mechanisms involved in protein quality surveillance play a role in late onset diseases and one chapter deals with this topic. Molecular analyses of genes and proteins continue to shed light on the pathogenesis of malformation syndromes and specific examples of such studies are presented. There is growing evidence that late onset disorders such as Parkinson disease, are frequently the end result of defects in functioning of components in different pathways and examples of these are discussed. There is evidence that genetic variation determines differences in response to environmental insults. Genetic variations in complement factor genes are an example of this and are discussed in the context of macular degeneration and pathogenesis of hemolytic uremic syndrome in response exposure to E coli Shiga toxin. In the final chapter the author briefly summarizes key features of the cascade of events that constitute functional genomics.

Diagnostic Imaging Pediatric Neuroradiology E Book

Diagnostic Imaging  Pediatric Neuroradiology E Book Book
Author : Kevin R. Moore
Publisher : Elsevier Health Sciences
Release : 2014-11-06
ISBN : 032337543X
Language : En, Es, Fr & De

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Book Description :

From training to practice, Diagnostic Imaging: Pediatric Neuroradiology is a must have reference for all health professionals who order, perform, or interpret imaging studies of the brain, head, neck, spinal column, and spinal cord in children. This meticulously updated second edition offers the latest knowledge in the diagnosis of all common and many uncommon pediatric nervous system disorders. Each diagnosis includes clinical presentation(s) of affected patients, the best sequences for imaging analysis, expected imaging sequences (in both common and uncommon presentations), and imaging examples of key features. Additional information is included concerning the pathophysiology and pathology of the disorders being discussed as well as basic information concerning the causative genes (when appropriate). Introductory chapters in multiple sections provide background on basic embryology, anatomy, and physiology as well as typical imaging features of normal structures. Highly visual and to-the-point, Diagnostic Imaging: Pediatric Neuroradiology is written in classic Amirsys style–both print and electronic content is viewable in easy-to-read bulleted lists supported by clearly described images. Meticulous updates throughout reflect advances in our understanding, reclassifications, and discoveries of entirely new disorders and groups of disorders Comprehensive discussions of common and uncommon disorders of the pediatric nervous system Hot topics covered include genetics and molecular pathways and common and uncommon disorders affecting the brain, head, neck, and/or spine of children Heavily illustrated along with hundreds of annotated images Bulleted and succinct text format distills essential information for fast and easy comprehension

Synaptic Assembly and Neural Circuit Development

Synaptic Assembly and Neural Circuit Development Book
Author : Jaewon Ko,Chen Zhang
Publisher : Frontiers Media SA
Release : 2018-11-02
ISBN : 2889456307
Language : En, Es, Fr & De

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Book Description :

Download Synaptic Assembly and Neural Circuit Development book written by Jaewon Ko,Chen Zhang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.