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Spine Phenotypes

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Abnormal Skeletal Phenotypes

Abnormal Skeletal Phenotypes Book
Author : Alessandro Castriota-Scanderbeg,Bruno Dallapiccola
Publisher : Springer Science & Business Media
Release : 2006-03-20
ISBN : 9783540303619
Language : En, Es, Fr & De

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Book Description :

Taking a symptom-oriented approach, this book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. Its clear structure makes it an essential, practical guide for radiologists, geneticists, and pediatricians.

Dendritic spines from shape to function

Dendritic spines  from shape to function Book
Author : Nicolas Heck,Ruth Benavides-Piccione
Publisher : Frontiers Media SA
Release : 2016-02-03
ISBN : 2889197662
Language : En, Es, Fr & De

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Book Description :

One fundamental requisite for a comprehensive view on brain function and cognition is the understanding of the neuronal network activity of the brain. Neurons are organized into complex networks, interconnected through synapses. The main sites for excitatory synapses in the brain are thin protrusions called dendritic spines that emerge from dendrites. Dendritic spines have a distinct morphology with a specific molecular organization. They are considered as subcellular compartments that constrain diffusion and influence signal processing by the neuron and, hence, spines are functional integrative units for which morphology and function are tightly coupled. The density of spines along the dendrite reflects the levels of connectivity within the neuronal network. Furthermore, the relevance of studying dendritic spines is emphasized by the observation that their morphology changes with synaptic plasticity and is altered in many psychiatric disorders. The present Research Topic deals with some of the most recent findings concerning dendritic spine structure and function, showing that, in order to understand how brain neuronal activity operates, these two factors should be regarded as being intrinsically linked.

Atlas of Spinal Imaging

Atlas of Spinal Imaging Book
Author : Philip K. Louie, MD,Howard S. An, MD,Dino Samartzis
Publisher :
Release : 2021-02
ISBN : 9780323761116
Language : En, Es, Fr & De

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Book Description :

Spine-related pain is the world's leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging Phenotypes: Classifications and Radiographic Measurements is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. Helps readers better understanding spinal phenotypes and their imaging, and how today's knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. Includes validated classification systems that complement the phenotypes and radiographic measurements. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.

Rotifera IX

Rotifera IX Book
Author : La-orsri Sanoamuang
Publisher : Springer Science & Business Media
Release : 2001
ISBN : 9780792368700
Language : En, Es, Fr & De

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Book Description :

This volume is a record of the proceedings of the IXth International Rotifer Symposium, which was held in Khon Kaen, Thailand, on January 16-23, 2000. It contains reviews and research papers dealing with diverse aspects of scientific research related to Rotifera and their ecology. Some of the topics addressed are: taxonomy and zoogeography, ecology, phylogeny and evolution, physiology, biochemistry and population genetics, aquaculture, and ecotoxicology. This book contains a compilation of contemporary rotifer-related research, and is the eighth of a series of rotifer symposium proceedings published in Developments of Hydrobiology. This update of Rotifera studies should be of great interest to invertebrate zoologists, hydrobiologists, ecologists, and aquaculturists, particularly those interested in freshwater habitats.

Reelin Related Neurological Disorders and Animal Models

Reelin Related Neurological Disorders and Animal Models Book
Author : Laura Lossi,Adalberto Merighi,Gabriella D'Arcangelo
Publisher : Frontiers Media SA
Release : 2017-03-14
ISBN : 2889451119
Language : En, Es, Fr & De

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Book Description :

The Reeler mutation was so named because of the alterations in gait that characterize homozygous mice. Several decades after the description of the Reeler phenotype, the mutated protein was discovered and named Reelin (Reln). Reln controls a number of fundamental steps in embryonic and postnatal brain development. A prominent embryonic function is the control of radial neuronal migration. As a consequence, homozygous Reeler mutants show disrupted cell layering in cortical brain structures. Reln also promotes postnatal neuronal maturation. Heterozygous mutants exhibit defects in dendrite extension and synapse formation, correlating with behavioral and cognitive deficits that are detectable at adult ages. The Reln-encoding gene is highly conserved between mice and humans. In humans, homozygous RELN mutations cause lissencephaly with cerebellar hypoplasia, a severe neuronal migration disorder that is reminiscent of the Reeler phenotype. In addition, RELN deficiency or dysfunction is also correlated with psychiatric and cognitive disorders, such as schizophrenia, bipolar disorder and autism, as well as some forms of epilepsy and Alzheimer's disease. Despite the wealth of anatomical studies of the Reeler mouse brain, and the molecular dissection of Reln signaling mechanisms, the consequences of Reln deficiency on the development and function of the human brain are not yet completely understood. This Research Topic include reviews that summarize our current knowledge of the molecular aspects of Reln function, original articles that advance our understanding of its expression and function in different brain regions, and reviews that critically assess the potential role of Reln in human psychiatric and cognitive disorders.

Dendrites Advances in Research and Application 2011 Edition

Dendrites  Advances in Research and Application  2011 Edition Book
Author : N.A
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464951934
Language : En, Es, Fr & De

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Book Description :

Dendrites: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Dendrites in a compact format. The editors have built Dendrites: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Dendrites in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Dendrites: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Spine Imaging E Book

Spine Imaging E Book Book
Author : Efrat Saraf-Lavi
Publisher : Elsevier Health Sciences
Release : 2012-06-04
ISBN : 1455751367
Language : En, Es, Fr & De

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Book Description :

Spine Imaging, a title in the popular Case Review Series, helps you effectively prepare for certification, recertification, and practice in spine imaging with case studies that test your knowledge of all essential topics. This medical reference book will show you how to make confident, final diagnoses through accurate pattern recognition, clinical correlation, and differential diagnosis. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Prepare effectively by reviewing 160 spine imaging cases, organized by level of difficulty, that mimic the new format of radiology certification and recertification exams. Every case includes at least 3 images and 4 multiple-choice review questions, along with rationales that explain why each answer is correct or incorrect. Ensure your knowledge is up to date with the aid of new and updated spinal imaging case studies covering modalities such as Spinal MRA imaging, SWI, CINE CSF flow, MR myelography and peripheral nerve imaging. New cases include discal cyst, polymyalgia rheumatica, Gaucher disease, pigmented villonodular synovitis, ventriculus terminalis cyst, and much more.

The Comprehensive Treatment of the Aging Spine E Book

The Comprehensive Treatment of the Aging Spine E Book Book
Author : James J. Yue,Richard Guyer,J. Patrick Johnson,Larry T. Khoo,Stephen H. Hochschuler
Publisher : Elsevier Health Sciences
Release : 2010-12-03
ISBN : 1455700037
Language : En, Es, Fr & De

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Book Description :

The Comprehensive Treatment of the Aging Spine provides all the state-of-the-art coverage you need on both operative and non-operative treatments for different clinical pathologies of the aging spine. Dr James Yue and a team of talented, pioneering orthopedic surgeons and neurosurgeons cover hot topics like minimally invasive fusion, dynamic stabilization, state-of-the-art intraspinous and biologic devices, and more...in print and online. Search the full text and access a video library online at expertconsult.com. Master the very latest techniques and technologies through detailed step-by-step surgical instructions, tips, and pearls. Stay current on the state-of-the-art in intraspinous and biologic devices—such as Stent (Alphatec) and Optimesh Spineology; thoracic techniques—kyphoplasty, vertebroplasty, and spacers; and conservative treatment modalities—including injection therapies, acupuncture, and yoga. Make expert-guided decisions on techniques and device selection using the collective clinical experience of pioneering editors and contributors. Identify the advantages and disadvantages for the full range of available microsurgical and endoscopic techniques for management of cervical, thoracic, and lumbar spine pathology—minimally invasive fusion, reconstruction, decompression, and dynamic stabilization.

Magnetic Resonance Imaging of the Brain and Spine

Magnetic Resonance Imaging of the Brain and Spine Book
Author : Scott W. Atlas
Publisher : Lippincott Williams & Wilkins
Release : 2009
ISBN : 9780781769853
Language : En, Es, Fr & De

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Book Description :

Established as the leading textbook on imaging diagnosis of brain and spine disorders, Magnetic Resonance Imaging of the Brain and Spine is now in its Fourth Edition. This thoroughly updated two-volume reference delivers cutting-edge information on nearly every aspect of clinical neuroradiology. Expert neuroradiologists, innovative renowned MRI physicists, and experienced leading clinical neurospecialists from all over the world show how to generate state-of-the-art images and define diagnoses from crucial clinical/pathologic MR imaging correlations for neurologic, neurosurgical, and psychiatric diseases spanning fetal CNS anomalies to disorders of the aging brain. Highlights of this edition include over 6,800 images of remarkable quality, more color images, and new information using advanced techniques, including perfusion and diffusion MRI and functional MRI. A companion Website will offer the fully searchable text and an image bank.

Principles and Practice of Lifespan Developmental Neuropsychology

Principles and Practice of Lifespan Developmental Neuropsychology Book
Author : Jacobus Donders,Scott J. Hunter
Publisher : Cambridge University Press
Release : 2010-01-14
ISBN : 1139485644
Language : En, Es, Fr & De

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Book Description :

Lifespan developmental neuropsychology is the study of the systematic behavioral, cognitive, and psychosocial changes and growth that occur across infancy, adolescence, adulthood and later life. This book provides insight into how brain-behavior relationships change over time, how disorders differ in presentation across the lifespan, and what longer-term outcomes look like. Providing practical guidance in a succinct and accessible format, this book covers the most common neurodevelopmental, behavioral and cognitive disorders, including but not limited to ADHD, cerebral palsy, traumatic brain injury, and epilepsy. Key points concerning the practice of developmental neuropsychology are emphasized in order to aid understanding of neuropsychological development and its impact on behavior, emotion, cognition, and social integration. This will be essential reading for advanced graduate students and early career professionals in the fields of neuropsychology, pediatric psychology, clinical psychology, school psychology, and rehabilitation psychology, as well as practitioners in the allied fields that interact with neuropsychology.

AO Spine Manual Books and DVD

AO Spine Manual  Books and DVD Book
Author : Max Aebi,Vincent Arlet
Publisher : Thieme
Release : 2007-04-05
ISBN : 3131650419
Language : En, Es, Fr & De

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Book Description :

Based on the successful format of AO courses, this two-volume reference is a comprehensive manual for the latest AO spine techniques. Principles and Techniques begins with a complete review of basic science concepts, helping the reader understand the biomechanics, biology, and the surgical anatomy of the spine. This volume provides a systematic overview of spinal instrumentation, computer-assisted surgery, and anesthesia considerations. Clinical Applications presents a compilation of clinical cases addressing the most common spinal problems, such as spinal trauma, tumors, infections, inflammatory processes, deformities, degenerative spinal diseases, and metabolic bone disease. For each case, the book guides the reader from case presentation, through rationale for surgical treatment, and to non-operative treatment options. The authors describe potential complications in spine surgery and outcomes. Throughout both volumes, high-quality photographs and drawings illustrate surgical techniques step-by-step and demonstrate key concepts of management. Clear, easy-to-reference bulleted lists and shaded text boxes facilitate rapid review of important learning points.

Spine Surgery in an Aging Population

Spine Surgery in an Aging Population Book
Author : Nathaniel P. Brooks,Andrea L. Strayer
Publisher : Thieme
Release : 2019-10-28
ISBN : 1626239150
Language : En, Es, Fr & De

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Book Description :

An invaluable primer on the surgical and nonsurgical treatment of aging patients with spine conditions The growing population of people aged 65 and older has significant implications for health care systems and spine care providers. Older patients today demand interventions that enable them to return to a functional lifestyle. Treatment of degenerative spine disease in aging adults requires in-depth understanding of changes in physiology, biomechanics, function, and modifiable risk factors. Equally important, providers need to listen to patients, diagnose thoughtfully, learn about the person's goals, and teach them in plain language about the risks, alternatives, and expectations of treatment options. This foundation is critical to developing informed patient-centered treatment plans to improve outcomes. Spine Surgery in an Aging Population by Nathaniel Brooks, Andrea Strayer, and a cadre of global contributors reflects a rich array of expertise. With multidisciplinary contributions from renowned specialists in neurosurgery, orthopaedic surgery, geriatrics, and rehabilitation, the book provides invaluable insights on caring for aging adults with degenerative spine disease. Throughout 21 chapters, readers are provided with key concepts, expert knowledge, and effective management strategies to avoid complications and improve outcomes for older adult spine patients. Key Highlights Diagnosis and treatment of osteoporosis to help prevent fractures and optimize treatment approaches prior to elective surgery Management of common pathologies of the aging spine such as cervical spondylosis, lumbar stenosis, spondylolisthesis, degenerative scoliosis and trauma Special topics include value-based care, nonsurgical management of spinal pain, vertebral augmentation, minimally invasive surgery, and instrumentation considerations This one-stop compendium is essential reading for orthopaedic and neurosurgical residents and fellows, as well as veteran surgeons and allied health providers who care for older adults with spine conditions.

Clinical Anatomy of the Spine Spinal Cord and ANS E Book

Clinical Anatomy of the Spine  Spinal Cord  and ANS   E Book Book
Author : Gregory D. Cramer,Susan A. Darby
Publisher : Elsevier Health Sciences
Release : 2017-04-05
ISBN : 0323082319
Language : En, Es, Fr & De

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Book Description :

This one-of-a-kind text describes the specific anatomy and neuromusculoskeletal relationships of the human spine, with special emphasis on structures affected by manual spinal techniques. A comprehensive review of the literature explores current research of spinal anatomy and neuroanatomy, bringing practical applications to basic science. A full chapter on surface anatomy includes tables for identifying vertebral levels of deeper anatomic structures, designed to assist with physical diagnosis and treatment of pathologies of the spine, as well as evaluation of MRI and CT scans. High-quality, full-color illustrations show fine anatomic detail. Red lines in the margins draw attention to items of clinical relevance, clearly relating anatomy to clinical care. Spinal dissection photographs, as well as MRIs and CTs, reinforce important anatomy concepts in a clinical context. Revisions to all chapters reflect an extensive review of current literature. New chapter on the pediatric spine discusses the unique anatomic changes that take place in the spine from birth through adulthood, as well as important clinical ramifications. Over 170 additional illustrations and photos enhance and support the new information covered in this edition.