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Signal Transduction In Physiology Pathophysiology And Drug Discovery

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Signal Transduction in the Cardiovascular System in Health and Disease

Signal Transduction in the Cardiovascular System in Health and Disease Book
Author : Ashok K. Srivastava,Madhu B. Anand-Srivastava
Publisher : Springer
Release : 2014-10-31
ISBN : 9781489998569
Language : En, Es, Fr & De

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Book Description :

Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Signal Transduction in the Cardiovascular System in Health and Disease

Signal Transduction in the Cardiovascular System in Health and Disease Book
Author : Ashok K. Srivastava,Madhu B. Anand-Srivastava
Publisher : Springer Science & Business Media
Release : 2008-09-20
ISBN : 0387095527
Language : En, Es, Fr & De

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Book Description :

Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Signal Transduction in the Cardiovascular System in Health and Disease

Signal Transduction in the Cardiovascular System in Health and Disease Book
Author : Ashok K. Srivastava,Madhu B. Anand-Srivastava
Publisher : Springer
Release : 2008-09-20
ISBN : 9780387095523
Language : En, Es, Fr & De

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Book Description :

Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Tau Rings and Wreath Product Representations

Tau Rings and Wreath Product Representations Book
Author : Peter Hoffman
Publisher : Springer
Release : 2006-11-15
ISBN : 3540348603
Language : En, Es, Fr & De

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Book Description :

Download Tau Rings and Wreath Product Representations book written by Peter Hoffman, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

RGS Protein Physiology and Pathophysiology

RGS Protein Physiology and Pathophysiology Book
Author : Anonim
Publisher : Academic Press
Release : 2015-06-23
ISBN : 0128029544
Language : En, Es, Fr & De

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Book Description :

RGS Protein Physiology and Pathophysiology describes the current, state-of-the-art research occurring in the laboratories of leaders in the RGS protein field that utilize genetic mouse models to interrogate the function of RGS proteins in vivo. Each chapter describes the elucidated role of a specific RGS protein or family of RGS proteins in normal physiology and/or disease with particular emphasis on how these discoveries inform healthcare and drug discovery. The work is a timely reference as drugs targeting G protein coupled receptors represent 40% of currently marketed therapeutics. Brings together information on the current state of the RGS protein field Contains comprehensive descriptions of the known pathophysiological and physiological functions of RGS proteins, the first such undertaking Gives particular emphasis to the ways these discoveries inform healthcare and drug discovery

Receptor Receptor Interactions

Receptor Receptor Interactions Book
Author : P. Michael Conn
Publisher : Academic Press
Release : 2013-10-18
ISBN : 0124104703
Language : En, Es, Fr & De

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Book Description :

This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come. Covers sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes Chapters are written by experts in the field Cutting-edge material

Pulmonary Vasculature Redox Signaling in Health and Disease

Pulmonary Vasculature Redox Signaling in Health and Disease Book
Author : Yong-Xiao Wang
Publisher : Springer
Release : 2017-10-18
ISBN : 3319632450
Language : En, Es, Fr & De

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Book Description :

The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature. Content from outstanding investigators with unique expertise and skills of molecular and cell biology, biochemistry, physiology, pharmacology, biophysics, biotechnology and medicine will update our current out-of-date concepts with new knowledge. Rapidly increasing scientific studies have gathered a large volume of novel and important information on redox signaling in healthy and diseased pulmonary vasculature. This volume covers the need for a cohesive book to display state-of-the-art advances in the field. The second major aim of this book is to help direct future research. Redox signaling is a major molecular process involved in almost every physiologic cellular response in the pulmonary vasculature including energy metabolism, host defense, gene expression, contraction, proliferation, and migration. Aberrancy in this important signaling pathway leads to a critical role in the development of nearly all pulmonary diseases, such as pulmonary hypertension, cor pulmonale, pulmonary edema, and vasculitis, among others.

New Scientist

New Scientist Book
Author : Anonim
Publisher : Unknown
Release : 2007-10
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download New Scientist book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development Book
Author : Ali S. Faqi
Publisher : Academic Press
Release : 2012-10-18
ISBN : 0123878160
Language : En, Es, Fr & De

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Book Description :

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. Chapters written by world-renowned contributors who are experts in their fields Includes the latest research in preclinical drug testing and international guidelines Covers preclinical toxicology in small molecules and biologics in one single source

Physiology and Pathophysiology of the Heart

Physiology and Pathophysiology of the Heart Book
Author : Nick Sperelakis,Nicholas Sperelakis
Publisher : Springer
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The third edition includes 14 new chapters covering topics that were not covered in the second edition. These include two new chapters on the molecular structure of ion channels and several new chapters on the ionic channels of myocardial cells, vascular smooth muscle cells, and endothelial cells. New chapters are also included on release of Ca[superscript 2+] from the SR, and on the action of phospholipids released during ischemia on ion channels and production of disrhythmias. These new additions make Physiology and Pathophysiology of the Heart, Third Edition substantially more complete and up-to-date with respect to recent developments in cardiovascular science.

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chaperokine Activity of Heat Shock Proteins

Chaperokine Activity of Heat Shock Proteins Book
Author : Alexzander A. A. Asea,Punit Kaur
Publisher : Springer
Release : 2019-02-01
ISBN : 3030022544
Language : En, Es, Fr & De

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Book Description :

Chaperokine, is a term that describes the unique function of extracellular heat shock protein (eHsp) as both chaperone and cytokine. The cellular consequence of binding and signaling of eHsp is the stimulation of a potent and long lasting immune response. eHsp induces a plethora of immune responses including the release of bioactive mediators like cytokines, chemokines, nitric oxide, apotogenic mediator, stimulation of the innate and adaptive immune response, migration and maturation of dendritic cells (DC) and the enhancement of natural killer cell-mediated cellular cytotoxicity. The book Chaperokine Activity of Heat Shock Proteins provides the most comprehensive review on contemporary knowledge on the chaperokine activity of heat shock proteins (HSP) in biology and medicine. Using an integrative approach to understanding the chaperokine activity of HSP, the contributors provide a synopsis of novel mechanisms, signal transduction pathways and how the principles of the chaperokine activity of HSP has been harnessed for therapeutic gain. To enhance the ease of reading and comprehension this book has been subdivided into various section, including; Section I, reviews current progress on our understanding of Immunological and Inflammatory Responses; Section II, evaluates the role of Physiological Responses and Section III, focuses the reader on the Therapeutic Approach. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychologists, Human Physiology, Zoologists, Botanists, Biotechnology, Molecular Medicine, Infectious Diseases Experts, Pathologists, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

European Research Centres A N

European Research Centres  A N Book
Author : Anonim
Publisher : Stockton Press
Release : 1994-11
ISBN : 9781561591176
Language : En, Es, Fr & De

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Book Description :

Download European Research Centres A N book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Kyoto University Bulletin

Kyoto University Bulletin Book
Author : Kyōto Daigaku
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Kyoto University Bulletin book written by Kyōto Daigaku, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Directory of Graduate Studies

The Directory of Graduate Studies Book
Author : Anonim
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Directory of Graduate Studies book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The FASEB Journal

The FASEB Journal Book
Author : Anonim
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The FASEB Journal book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Program Abstracts 10th International Congress of Endocrinology ICE 96

Program   Abstracts  10th International Congress of Endocrinology  ICE 96  Book
Author : Anonim
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Program Abstracts 10th International Congress of Endocrinology ICE 96 book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

White Paper on Education Culture Sports Science and Technology

White Paper on Education  Culture  Sports  Science and Technology Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download White Paper on Education Culture Sports Science and Technology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Science

Science Book
Author : John Michels
Publisher : Unknown
Release : 2001-06
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Science book written by John Michels, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.