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Side Reactions In Peptide Synthesis

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Side Reactions in Peptide Synthesis

Side Reactions in Peptide Synthesis Book
Author : Yi Yang
Publisher : Academic Press
Release : 2015-09-01
ISBN : 0128011815
Language : En, Es, Fr & De

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Book Description :

Side Reactions in Peptide Synthesis, based on the author’s academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis. This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development. While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay. Each chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction. Provides a systematic examination on how to troubleshoot and minimize the most frequent side reactions in peptide synthesis Gives chemists the background information and the practical tools they need to successfully troubleshoot and improve results Includes optimization-oriented analysis of side reactions in peptide synthesis for improved industrial process development in peptidyl API (active pharmaceutical ingredient) production Answers the growing, global need for improved, replicable processes to avoid impurities and maintain the integrity of the end product. Presents a thorough discussion of critical factors in peptide synthesis which are often neglected or underestimated by chemists Covers solid phase and solution phase methodologies, and provides abundant references for further exploration

Principles of Peptide Synthesis

Principles of Peptide Synthesis Book
Author : Miklos Bodanszky
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642780563
Language : En, Es, Fr & De

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Book Description :

Principles of Peptide Synthesis is a very successful book by one of the pioneers of contemporary bioorganic synthesis. Its first edition proved a valuable source that is kept close to the work bench for frequent consulting. Any researcher planning the formation of the peptide bond, be it for the synthesis of a peptide chain or a cyclic peptide, benefits from the author's experience. The concise and critical treatment of the steps involved: protection, activation and bond formation require careful planning to avoid racemization and undesired side reactions. The second edition has been completely revised and updated. New procedures that have been developed since the first edition was published and that did not fit into the original are added in a separate chapter. This separation of old and new make it possible to assess new ideas and discern novel trends.

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Psychopharmacology Bulletin

Psychopharmacology Bulletin Book
Author : Anonim
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Psychopharmacology Bulletin book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Peptides

The Peptides Book
Author : Sidney Udenfriend,Johannes Meienhofer
Publisher : Unknown
Release : 1987-11
ISBN : 9780123042095
Language : En, Es, Fr & De

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Book Description :

Download The Peptides book written by Sidney Udenfriend,Johannes Meienhofer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins Book
Author : Daniel R. Marshak,Darrell T. Liu,Teh-Yung Liu
Publisher : Cold Spring Harbor Laboratory Press
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Therapeutic Peptides and Proteins book written by Daniel R. Marshak,Darrell T. Liu,Teh-Yung Liu, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Peptides

The Peptides Book
Author : Erhard Gross,Johannes Meienhofer
Publisher : Unknown
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Peptides book written by Erhard Gross,Johannes Meienhofer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Major Methods of Peptide Bond Formation

Major Methods of Peptide Bond Formation Book
Author : Erhard Gross,Johannes Meienhofer
Publisher : Elsevier
Release : 2014-05-10
ISBN : 1483217965
Language : En, Es, Fr & De

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Book Description :

The Peptides: Analysis, Synthesis, Biology, Volume 1: Major Methods of Peptide Bond Formation provides comprehensive and critical reviews of important developments in three major areas of peptide research—analysis, synthesis, and biology. This book discusses the nature of the peptide bond, coupling between amino acid residues, and catalysis of active ester reactions. The formation of hydrazides, reactions of carbodiimides with amines, and mixed carbonic anhydride method of peptide synthesis are also elaborated. This publication likewise covers the control of racemization during peptide synthesis, strategies for minimizing racemization during amide-forming steps, and assays for chiral purity. This volume is suitable for students, specialists, and scientists from a broad range of disciplines concerned with peptides.

Banbury Report

Banbury Report Book
Author : Banbury Center
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Banbury Report book written by Banbury Center, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Peptides Protection of functional groups in peptide synthesis

The Peptides  Protection of functional groups in peptide synthesis Book
Author : Erhard Gross,Johannes Meienhofer
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Peptides Protection of functional groups in peptide synthesis book written by Erhard Gross,Johannes Meienhofer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Amino Acid and Peptide Synthesis

Amino Acid and Peptide Synthesis Book
Author : John H. Jones,John Jones
Publisher : Oxford University Press, USA
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The principal methods for the synthesis of amino acids and peptides are outlined in this concise introduction. With its emphasis on chemical principles and strategies, the book should be of value to all undergraduate chemistry students.

Amino acid Peptide Protein Abstracts

Amino acid  Peptide   Protein Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1979-07
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Amino acid Peptide Protein Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

I Stereoselective N glycosylation by Staudinger Ligation

I  Stereoselective N glycosylation by Staudinger Ligation Book
Author : Yi He
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download I Stereoselective N glycosylation by Staudinger Ligation book written by Yi He, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Russian Journal of Bioorganic Chemistry

Russian Journal of Bioorganic Chemistry Book
Author : Anonim
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Russian Journal of Bioorganic Chemistry book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Design Synthesis and Characterization of Beta sheet Peptides and Proteins

Design  Synthesis  and Characterization of Beta sheet Peptides and Proteins Book
Author : Natàlia Carulla Casanovas
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Design Synthesis and Characterization of Beta sheet Peptides and Proteins book written by Natàlia Carulla Casanovas, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Use and Standardization of Chemically Defined Antigens

Use and Standardization of Chemically Defined Antigens Book
Author : Girish N. Vyas,W. Hennessen
Publisher : S Karger Ag
Release : 1986
ISBN : 9783805542807
Language : En, Es, Fr & De

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Book Description :

Download Use and Standardization of Chemically Defined Antigens book written by Girish N. Vyas,W. Hennessen, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Peptides Methods of peptide synthesis v 2 Synthesis occurence and action of biologically active polypeptides

The Peptides  Methods of peptide synthesis  v  2  Synthesis  occurence  and action of biologically active polypeptides Book
Author : Eberhard Schröder,Klaus Lübke
Publisher : Unknown
Release : 1965
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Peptides Methods of peptide synthesis v 2 Synthesis occurence and action of biologically active polypeptides book written by Eberhard Schröder,Klaus Lübke, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biochemical and Organic Compounds for Research and Diagnostic Clinical Reagents

Biochemical and Organic Compounds for Research and Diagnostic Clinical Reagents Book
Author : Sigma Chemical Company
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biochemical and Organic Compounds for Research and Diagnostic Clinical Reagents book written by Sigma Chemical Company, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Peptides Synthesis occurrence and action of biologically active polypeptides

The Peptides  Synthesis  occurrence  and action of biologically active polypeptides Book
Author : Eberhard Schröder,Klaus Lübke
Publisher : Unknown
Release : 1965
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Peptides Synthesis occurrence and action of biologically active polypeptides book written by Eberhard Schröder,Klaus Lübke, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.