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Sex Gender And Epigenetics

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Sex Gender and Epigenetics

Sex  Gender  and Epigenetics Book
Author : Marianne J. Legato
Publisher : Academic Press
Release : 2023-03-01
ISBN : 9780128239377
Language : En, Es, Fr & De

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Book Description :

Sex, Gender, and Epigenetics: From Molecule to Bedside explores the complex interplay of sex and gender-based influences on gene expression via epigenetic mechanisms. This volume provides an overview of the field and evidence gathered to-date, followed by a discussion of epigenetic pathways by which biological sex and the impact of the environment collaborate to regulate genetic function. The book also analyzes the impact of ancestors' environmental experience on subsequent generations, and describes the nature of sex-specific transmission of environmentally induced epigenetic modifications. Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics. In all chapters, authors tie basic biological findings to possible applications in the clinic, drug discovery, and reproductive medicine.

Bridging Gaps Between Sex and Gender in Neurosciences

Bridging Gaps Between Sex and Gender in Neurosciences Book
Author : Annie Duchesne,Meng-Chuan Lai,Gillian Einstein,Belinda Pletzer,Marina A. Pavlova
Publisher : Frontiers Media SA
Release : 2020-07-14
ISBN : 2889638650
Language : En, Es, Fr & De

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Book Description :

Download Bridging Gaps Between Sex and Gender in Neurosciences book written by Annie Duchesne,Meng-Chuan Lai,Gillian Einstein,Belinda Pletzer,Marina A. Pavlova, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Challenges of Interdisciplinary Research in the Field of Critical Sex Gender Neuroscience

Challenges of Interdisciplinary Research in the Field of Critical  Sex  Gender  Neuroscience Book
Author : Hannah Fitsch,Flora Lysen,Suparna Choudhury
Publisher : Frontiers Media SA
Release : 2022-02-17
ISBN : 2889742865
Language : En, Es, Fr & De

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Book Description :

Download Challenges of Interdisciplinary Research in the Field of Critical Sex Gender Neuroscience book written by Hannah Fitsch,Flora Lysen,Suparna Choudhury, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Gender Medicine

Gender Medicine Book
Author : Marek Glezerman
Publisher : Duckworth Overlook
Release : 2017-09-21
ISBN : 9780715652244
Language : En, Es, Fr & De

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Book Description :

Despite the fact that cultural differences between genders are becoming obsolete, the differences between male and female bodies are nevertheless very real, and go well beyond the obvious sexual and reproductive variances: men and women absorb medication, feel pain, and even display early symptoms of heart attacks differently. And yet the medical establishment treats male and female patients as though their needs were identical. In fact, medical research is still done predominately on men, and the results applied to the treatment of women. This is clearly problematic, and Gender Medicine calls for the reform of attitudes and practices, for all of us: GP and surgeon, researcher and patient.

Sex Differences in Neurology and Psychiatry

Sex Differences in Neurology and Psychiatry Book
Author : Anonim
Publisher : Elsevier
Release : 2020-09-30
ISBN : 0444641246
Language : En, Es, Fr & De

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Book Description :

Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Temperature Dependent Sex Determination in Vertebrates

Temperature Dependent Sex Determination in Vertebrates Book
Author : Nicole Valenzuela,Valentine A. Lance
Publisher : Smithsonian Institution Scholarly Press
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Edited by the world's foremost authorities on the subject, with essays by leading scholars in the field, this work shows how the sex of reptiles and many fish is determined not by the chromosomes they inherit but by the temperature at which incubation takes place.

Sex and Gender Differences in Pharmacology

Sex and Gender Differences in Pharmacology Book
Author : Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
Release : 2012-10-02
ISBN : 3642307264
Language : En, Es, Fr & De

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Book Description :

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Handbook of Epigenetics

Handbook of Epigenetics Book
Author : Trygve Tollefsbol
Publisher : Academic Press
Release : 2010-11-21
ISBN : 9780123757104
Language : En, Es, Fr & De

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Book Description :

Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and imprinting diseases are on the horizon. This comprehensive collection of reviews written by leaders in the field of epigenetics provides a broad view of this important and evolving topic. From molecular mechanisms and epigenetic technology to discoveries in human disease and clinical epigenetics, the nature and applications of the science will be presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders. Contributions by leading international investigators involved in molecular research and clinical and therapeutic applications Integrates methods and biological topics with basic and clinical discoveries Includes coverage of new topics in epigenetics such as prions, regulation of long-term memory by epigenetics, metabolic aspects of epigenetics, and epigenetics of neuronal disorders

The Maternal Imprint

The Maternal Imprint Book
Author : Sarah S. Richardson
Publisher : University of Chicago Press
Release : 2021-11-08
ISBN : 022680707X
Language : En, Es, Fr & De

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Book Description :

Leading gender and science scholar Sarah S. Richardson charts the untold history of the idea that a woman's health and behavior during pregnancy can have long-term effects on her descendants' health and welfare. The idea that a woman may leave a biological trace on her gestating offspring has long been a commonplace folk intuition and a matter of scientific intrigue, but the form of that idea has changed dramatically over time. Beginning with the advent of modern genetics at the turn of the twentieth century, biomedical scientists dismissed any notion that a mother—except in cases of extreme deprivation or injury—could alter her offspring’s traits. Consensus asserted that a child’s fate was set by a combination of its genes and post-birth upbringing. Over the last fifty years, however, this consensus was dismantled, and today, research on the intrauterine environment and its effects on the fetus is emerging as a robust program of study in medicine, public health, psychology, evolutionary biology, and genomics. Collectively, these sciences argue that a woman’s experiences, behaviors, and physiology can have life-altering effects on offspring development. Tracing a genealogy of ideas about heredity and maternal-fetal effects, this book offers a critical analysis of conceptual and ethical issues—in particular, the staggering implications for maternal well-being and reproductive autonomy—provoked by the striking rise of epigenetics and fetal origins science in postgenomic biology today.

Pharmacoepigenetics

Pharmacoepigenetics Book
Author : Anonim
Publisher : Academic Press
Release : 2019-06-04
ISBN : 0128139404
Language : En, Es, Fr & De

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Book Description :

Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine. Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine

Why Men Never Remember and Women Never Forget

Why Men Never Remember and Women Never Forget Book
Author : Marianne J. Legato
Publisher : Rodale
Release : 2006-09-05
ISBN : 1594865272
Language : En, Es, Fr & De

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Book Description :

Why won't he ask for directions? Why does she always want to talk about the relationship? Why is it so hard for men and women to understand each other . . . and what can we do about it? These are the kinds of questions that are resolved at last in this fascinating book from the founder of gender medicine. Dr. Marianne Legato not only confirms that men and women are different, but she uncovers the neuroscientific reasons behind the age-old disputes between the sexes, while providing a groundbreaking, authoritative, and reader-friendly guide to resolving them.

Principles of Gender Specific Medicine

Principles of Gender Specific Medicine Book
Author : Marianne J. Legato
Publisher : Academic Press
Release : 2022-08-01
ISBN : 0323958273
Language : En, Es, Fr & De

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Book Description :

Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans. We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine. Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human’s physiology

Gender Sex and Children s Play

Gender  Sex and Children s Play Book
Author : Jacky Kilvington,Ali Wood
Publisher : Bloomsbury Publishing
Release : 2016-08-11
ISBN : 1472523563
Language : En, Es, Fr & De

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Book Description :

Does gender, sex and sexuality influence children's play, and their learning? Can/should professionals try to influence children's gender and sexual concepts? Can/should professionals try to prevent gender stereotyping? These and other questions are explored in a lively and thought-provoking text that looks at why and how children inhabit or develop their gender and sexuality. Written in an approachable way and illustrated with case studies and linked to current research and theory, the book helps students, teachers and playworkers understand the debates about biology versus culture and social learning and how these impact on children's expression of gender and sexuality. Engaging the reader in a thorough reflection of their own views and approaches to the genderized and sexualized behaviour of children at play, this text is an invaluable guide for all those interested in the importance of play, gender and sexuality and how they relate to children's lives. Topics include: play and the behaviour of boys and girls within particular social contexts; play and girls' and boys' sexual behaviour and their associated feelings; play and children's self-concepts and expectations; the professional adult workers' role and the manifestation of genderized and/or sexualized play behaviour both in and outside a setting.

Sex Control in Aquaculture

Sex Control in Aquaculture Book
Author : Hanping Wang,Francesc Piferrer,Songlin Chen,Zhi-Gang Shen
Publisher : John Wiley & Sons
Release : 2018-11-08
ISBN : 1119127289
Language : En, Es, Fr & De

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Book Description :

A comprehensive resource that covers all the aspects of sex control in aquaculture written by internationally-acclaimed scientists Comprehensive in scope, Sex Control in Aquaculture first explains the concepts and rationale for sex control in aquaculture, which serves different purposes. The most important are: to produce monosex stocks to rear only the fastest-growing sex in some species, to prevent precocious or uncontrolled reproduction in other species and to aid in broodstock management. The application of sex ratio manipulation for population control and invasive species management is also included. Next, this book provides detailed and updated information on the underlying genetic, epigenetic, endocrine and environmental mechanisms responsible for the establishment of the sexes, and explains chromosome set manipulation techniques, hybridization and the latest gene knockout approaches. Furthermore, the book offers detailed protocols and key summarizing information on how sex control is practiced worldwide in 35 major aquaculture species or groups, including fish and crustaceans, and puts the focus on its application in the aquaculture industry. With contributions from an international panel of leading scientists, Sex Control in Aquaculture will appeal to a large audience: aquaculture/fisheries professionals and students, scientists or biologists working with basic aspects of fish/shrimp biology, growth and reproductive endocrinology, genetics, molecular biology, evolutionary biology, and R&D managers and administrators. This text explores sex control technologies and monosex production of commercially-farmed fish and crustacean species that are highly in demand for aquaculture, to improve feed utilization efficiency, reduce energy consumption for reproduction and eliminate a series of problems caused by mixed sex rearing. Thus, this book: Contains contributions from an international panel of leading scientists and professionals in the field Provides comprehensive coverage of both established and new technologies to control sex ratios that are becoming more necessary to increase productivity in aquaculture Includes detailed coverage of the most effective sex control techniques used in the world's most important commercially-farmed species Sex Control in Aquaculture is the comprehensive resource for understanding the biological rationale, scientific principles and real-world practices in this exciting and expanding field.

Biopolitics and Gender

Biopolitics and Gender Book
Author : Meredith W Watts Jr
Publisher : Routledge
Release : 2012-12-06
ISBN : 1136548912
Language : En, Es, Fr & De

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Book Description :

Here is an important book for social scientists interested in the influence of gender on certain types of behavior. Several perspectives are presented on the general topic of biopolitics and gender, including the points of view of brain science, endocrinology, ethology, psychophysiology, and such conventional interests as political attitudes, socialization, participation, social structure, and political hierarchy. The varied and provocative ideas explored in this volume will broaden discussions of gender beyond an exclusive focus on sex links to oppression and discrimination.

Gender Dysphoria and Disorders of Sex Development

Gender Dysphoria and Disorders of Sex Development Book
Author : Baudewijntje P.C. Kreukels,Thomas D. Steensma,Annelou L.C. de Vries
Publisher : Springer Science & Business Media
Release : 2013-07-01
ISBN : 1461474418
Language : En, Es, Fr & De

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Book Description :

This book provides a state of the art review on the care and treatment of and current scientific knowledge on gender dysphoria (GD) and disorders of sex development (DSD). The book elucidates the history, the present situation, and the newest developments and future perspectives in both research on GD and DSD and the clinical management of individuals with GD and DSD of all ages. With contributions from a selection of leading scientists and established clinicians in the field of GD and DSD, this is a unique and comprehensive book focusing on the etiology and developmental trajectories of GD and DSD regarding gender identity development, psychiatric comorbidity, classification dilemmas, ethical dilemmas in treatment, influences of societal stigmatization, and discussion of the medical and psychological implications and outcomes of treatment, and providing treatment guidelines for individuals with GD and DSD (distinct guidelines each for children, adolescents, and adults). By presenting not only an historic overview and the current state of the art, but also challenges for the future, the book aims to demonstrate the need for further research and to stimulate the development and improvement of the clinical care of individuals with GD and DSD.​

Genetics of Cardiovascular Disease

Genetics of Cardiovascular Disease Book
Author : Anonim
Publisher : Academic Press
Release : 2014-04-18
ISBN : 0123869498
Language : En, Es, Fr & De

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Book Description :

This volume of the esteemed Progress in Molecular Biology and Translational Science series focuses on cutting-edge research related to the genetics of cardiovascular disease. Written by top experts in the field, this volume covers a range of topics, including: Genetic models of atherosclerosis MicroRNAs in cardiovascular disease The role of the transcription factor KLF2 in vascular development and disease Zebrafish as models of cardiovascular disease and hematopoietic development Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. The authors are all experts in the field The reviews are in themselves comprehensive Each topic has the potential to lead to advances in therapy of cardiovascular disease

Epigenetic Mechanisms of Gene Regulation

Epigenetic Mechanisms of Gene Regulation Book
Author : Vincenzo E. A. Russo,Robert A. Martienssen,Arthur D. Riggs
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide Book
Author : Yogesh Dwivedi
Publisher : CRC Press
Release : 2012-06-25
ISBN : 143983881X
Language : En, Es, Fr & De

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Book Description :

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Females Are Mosaics

Females Are Mosaics Book
Author : Barbara Migeon
Publisher : Oxford University Press
Release : 2007-03-15
ISBN : 9780199720064
Language : En, Es, Fr & De

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Book Description :

Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome (inherited from their mother), females have two X chromosomes in every cell (one from each parent). The fathers copy works in some cells, while the mothers copy works in others. These two X chromosomes often function differently, especially if one carries a defective gene. Much has been written about the Y chromosome and its role in inducing maleness. This will be the first book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. Barbara Migeon, from the renowned McKusick-Nathan Institute at Johns Hopkins, is a major figure in clinical genetics and is eminently qualified to write this book, and she writes clearly and effectively. She describes both the underlying molecular mechanisms and the remarkable genetic consequences of X inactivation and its role in determining the biological concepts characteristic of women. Females are Mosaics will be valuable to geneticists, biologists, and all health professionals interested in women's health.