Seldin And Giebischs The Kidney

Book Description :

A classic nephrology reference for over 20 years, Seldin & Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch’s The Kidney is your number one source for information. * Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic. * Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics. * Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.

Book Description :

A classic nephrology reference for over 25years, Seldin and Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch’s The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions

Book Description :

A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information. * Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic. * Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics. * Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.

Book Description :

This edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. It offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction.

Book Description :

Download Seldin and Giebisch s the Kidney Control of intracellular pH book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Download Seldin and Giebisch s the kidney physiology pathophysiology book written by Robert J. Alpern,Steven C. Herbert, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

A classic nephrology reference for over 25years, Seldin and Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch's The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions

Book Description :

This book first appeared in English in 1983, as a translation of the 20th Edition of the long-established German textbook Physi%gie des Menschen. In this new English edition the text has been fundamentally "rejuvenated", to bring it up to date with the rapid advances in many areas of physiology and to incorporate many helpful suggestions from both readers and colleagues. In its scope and didac tic goals, the book remains as we set forth in the Preface to the First Edition, which follows. First, the content was substantially reorganized. The general aspects of cell physiol ogy and intercellular communication, which underlie the functions of all organs, were extracted from the various chapters and brought together in a separate intro ductory section. We are most grateful to our colleague J. DUDEL for undertaking this task. The second step was to make the text more concise in several places (for instance, the motor and somatovisceral systems previously occupied two chapters and have now been condensed into one). By these processes of condensation and distillation of the passages on general cell physiology, space was made for the necessary addi tions and expansions, with only a slight change in the overall length of the book.

Book Description :

Download Physiologie des Menschen book written by R.F. Schmidt,G. Thews, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. Experts in the field present the principles and experimental approaches for the study of interactions between pharmacologic compounds in relation to specific target organs. Diuretic Agents contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines. Written by experts in the field Covers all aspects of diuretic agents Includes information on the mechanisms of action and application of diuretics

Book Description :

This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.

Book Description :

Berne & Levy Physiology has long been respected for its scientifically rigorous approach – one that leads to an in-depth understanding of the body’s dynamic processes. The long-awaited 7th Edition by Drs. Bruce M. Koeppen and Bruce A. Stanton, continues this tradition of excellence. With integrated coverage of biophysics and neurophysiology, key experimental observations and examples, and full-color design and artwork, this mid-size text is "just right" for a strong understanding of this complex field. A logical and intuitive organ-system-based approach clearly describes all of the mechanisms that control and regulate bodily function. Authored by experts with both science and medical backgrounds. More "In the Clinic" and "At the Molecular Level" boxes help readers better understand and apply what they’ve learned. New coverage includes expanded discussions of gut and lung microbiota,; the limbic system; the hypthalamus and control of food intake; cardiac and vascular function curves during exercise; new aspects of lipid absorption; GI and metabolic consequences of bariatric surgery, the role of innate lymphoid cells in defense of the respiratory system, molecular mechanisms in normal and pathological muscle contraction; arterial pulse changes with age and the ankle-brachial index; regulation of the blood-brain barrier and cerebral blood flow; the regulation of phosphate; and thyroid hormone mechanism of action. Each chapter begins with an all-new bulleted list of questions and ends with key concepts covered in that chapter.

Book Description :

The action of diuretics including cellular mechanisms of action, pharmacokinetics, and clinical usage, with much emphasis placed on the most recent findings on the pharmacodynamics of the respective drugs. During the past twenty-five years since volume 14 on Diuretica was published in the Handbook series, the cellular mechanisms of action of diuretics have slowly been unravelled. Today, the role of action within the target cells is known for most of the substances discussed. This has provided a new basis not only for the understanding of drug action but also for secondary effects and interactions. The book represents a comprehensive reference work on the diverse groups of diuretics which are among the most frequently prescribed medications.

Book Description :

Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and kidney disease. Genetic abnormalities are carefully presented within the appropriate physiologic context so that readers will understand not only which genes are linked to which diseases but also which pathways lead from a genetic “disturbance” to the systemic appearance of disease. * Lays the essential foundation of mammalian genetics principles for medical professionals with little or no background in genetics * Analyzes specific renal diseases – both monogenic disorders confined to the kidney and systemic diseases with renal involvement – and explains their genetic causes *World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension)

Book Description :

When the six of us gathered to start planning for what was to be the Third Edition of Physiology of Membrane Disorders, it was clear that since 1986, when the Second Edition appeared, the field had experienced the dawning of a new era dominated by a change in focus from phenomenology to underlying mechanisms propelled by the power of molecular biology. In 1985, detailed molecular information was available for only three membrane transporters: the lac permease, bacterial rhodopsin, and the acetylcholine receptor. During the decade that has since elapsed, almost all of the major ion channels and transport proteins have been cloned, sequenced, mutagenized, and expressed in homologous as well as heterologous cells. Few, if any, of the transporters that were identified during the previous era have escaped the probings of the new molecular technologies and, in many instances, considerable insight has been gained into their mechanisms of function in health and disease. Indeed, in some instances novel, unexpected transporters have emerged that have yet to have their functions identified. The decision to adopt the new title Molecular Biology of Membrane Transport Disorders was a natural outgrowth of these considerations.

Book Description :

Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.

Book Description :

Download The Kidney book written by Donald W. Seldin,Gerhard H. Giebisch, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Cells maintain uneven distribution of Na, K and Ca ions across the cell membrane and membranes of intracellular organellae. Cells exert their functions by allowing for some ion to cross the membrane through ion channels which either produces an electrical effect across the membrane or switches on a series of chemical or physicochemical reactions. This is a comprehensive book about these vitally important ion channels with detailed description of the molecular structure and function and especially of activators and inhibitors. All chapters are written by renowned specialists in their field.

Book Description :

Download The Kidney book written by Donald W. Seldin,Gerhard H. Giebisch, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.